Published in Microbiology on September 01, 2008
Bacterial virulence in the moonlight: multitasking bacterial moonlighting proteins are virulence determinants in infectious disease. Infect Immun (2011) 1.99
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives. Appl Microbiol Biotechnol (2011) 1.85
Dynamic dissociating homo-oligomers and the control of protein function. Arch Biochem Biophys (2011) 1.06
Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosis. PLoS One (2013) 0.94
Computational characterization of moonlighting proteins. Biochem Soc Trans (2014) 0.85
Rhomboid homologs in mycobacteria: insights from phylogeny and genomic analysis. BMC Microbiol (2010) 0.82
Investigation of the essentiality of glutamate racemase in Mycobacterium smegmatis. J Bacteriol (2014) 0.78
Moonlighting role of a poly-gamma-glutamate synthetase component from Bacillus subtilis: insight into novel extrachromosomal DNA maintenance. Appl Environ Microbiol (2011) 0.75
Tracing the Repertoire of Promiscuous Enzymes along the Metabolic Pathways in Archaeal Organisms. Life (Basel) (2017) 0.75
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Res (2003) 7.56
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily. Nucleic Acids Res (2004) 1.73
Quantitative quality control in microarray experiments and the application in data filtering, normalization and false positive rate prediction. Bioinformatics (2003) 1.73
Conserved economics of transcription termination in eubacteria. Nucleic Acids Res (2002) 1.59
Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J Immunol (2008) 1.43
A comparison between SNaPshot, pyrosequencing, and biplex invader SNP genotyping methods: accuracy, cost, and throughput. J Biochem Biophys Methods (2004) 1.38
Genetic analysis of autoimmune type 1 diabetes mellitus in mice. 1991. J Immunol (2014) 1.37
DNA gyrase genes in Mycobacterium tuberculosis: a single operon driven by multiple promoters. J Bacteriol (2002) 1.35
Diverse functions of restriction-modification systems in addition to cellular defense. Microbiol Mol Biol Rev (2013) 1.32
Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility. Nucleic Acids Res (2003) 1.25
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood (2008) 1.19
Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation. PLoS One (2009) 1.19
Three color cDNA microarrays: quantitative assessment through the use of fluorescein-labeled probes. Nucleic Acids Res (2003) 1.18
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction. PLoS One (2007) 1.15
WebGeSTer DB--a transcription terminator database. Nucleic Acids Res (2010) 1.14
Transcriptional characterizations of differences between eutopic and ectopic endometrium. Endocrinology (2005) 1.11
Invited review: the mitochondrion in osteoarthritis. Mitochondrion (2002) 1.07
Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of genetic association studies. Am J Epidemiol (2006) 1.07
LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. J Cell Sci (2012) 1.05
Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death. Mol Biol Cell (2011) 1.05
GyrI: a counter-defensive strategy against proteinaceous inhibitors of DNA gyrase. EMBO Rep (2002) 1.04
The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression. Eur J Immunol (2009) 1.02
PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer. J Cell Sci (2011) 1.00
High levels of catalytic antibodies correlate with favorable outcome in sepsis. Proc Natl Acad Sci U S A (2005) 0.99
Promiscuous restriction is a cellular defense strategy that confers fitness advantage to bacteria. Proc Natl Acad Sci U S A (2012) 0.99
Chromosomally encoded gyrase inhibitor GyrI protects Escherichia coli against DNA-damaging agents. Arch Microbiol (2003) 0.99
Investigating the role of islet cytoarchitecture in its oscillation using a new beta-cell cluster model. PLoS One (2007) 0.98
Occurrence, divergence and evolution of intrinsic terminators across eubacteria. Genomics (2009) 0.98
Implications of high level pseudogene transcription in Mycobacterium leprae. BMC Genomics (2009) 0.98
Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella typhimurium and Salmonella typhi. J Antimicrob Chemother (2012) 0.97
Involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the BioBreeding rat. J Immunol (2004) 0.96
Ca(2+)-mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease. J Biol Chem (2004) 0.95
Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans. BMC Med Genet (2012) 0.95
YacG from Escherichia coli is a specific endogenous inhibitor of DNA gyrase. Nucleic Acids Res (2008) 0.92
Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. J Immunol (2006) 0.92
R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+. Nucleic Acids Res (2007) 0.91
Immune response against therapeutic factor VIII in hemophilia A patients--a survey of probable risk factors. Immunol Lett (2007) 0.91
Conditional silencing of topoisomerase I gene of Mycobacterium tuberculosis validates its essentiality for cell survival. FEMS Microbiol Lett (2014) 0.91
A novel approach for high-quality microarray processing using third-dye array visualization technology. IEEE Trans Nanobioscience (2003) 0.90
Carboxyl terminal domain basic amino acids of mycobacterial topoisomerase I bind DNA to promote strand passage. Nucleic Acids Res (2013) 0.90
Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity. J Neurochem (2011) 0.90
Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls. Cell Tissue Res (2010) 0.88
Comparison of promoter-specific events during transcription initiation in mycobacteria. Microbiology (2010) 0.87
Deciphering the distinct role for the metal coordination motif in the catalytic activity of Mycobacterium smegmatis topoisomerase I. J Mol Biol (2009) 0.87
Kinetic and catalytic properties of dimeric KpnI DNA methyltransferase. J Biol Chem (2002) 0.87
Indispensable, functionally complementing N and C-terminal domains constitute site-specific topoisomerase I. J Mol Biol (2006) 0.87
Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by cDNA microarrays. BMC Bioinformatics (2006) 0.86
KpnI restriction endonuclease and methyltransferase exhibit contrasting mode of sequence recognition. Nucleic Acids Res (2004) 0.86
Tardive oculogyric crisis associated with quetiapine use. J Clin Psychopharmacol (2013) 0.85
Evolution of sequence specificity in a restriction endonuclease by a point mutation. Proc Natl Acad Sci U S A (2008) 0.85
Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects. Immunogenetics (2009) 0.85
Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease. J Biol Chem (2007) 0.85
Distinct properties of hexameric but functionally conserved Mycobacterium tuberculosis transcription-repair coupling factor. PLoS One (2011) 0.85
Purification of RNA polymerase from mycobacteria for optimized promoter-polymerase interactions. Protein Expr Purif (2009) 0.84
Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding. Nucleic Acids Res (2006) 0.84
A hairpin near the 5' end stabilises the DNA gyrase mRNA in Mycobacterium smegmatis. Nucleic Acids Res (2002) 0.83
Dual role for transactivator protein C in activation of mom promoter of bacteriophage Mu. J Biol Chem (2006) 0.83
Novel insertion and deletion mutants of RpoB that render Mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription. Microbiology (2010) 0.83
Distinct and contrasting transcription initiation patterns at Mycobacterium tuberculosis promoters. PLoS One (2012) 0.83
Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase. Biol Chem (2006) 0.83
Regulation of lipid biosynthesis, sliding motility, and biofilm formation by a membrane-anchored nucleoid-associated protein of Mycobacterium tuberculosis. J Bacteriol (2013) 0.82
Increasing cleavage specificity and activity of restriction endonuclease KpnI. Nucleic Acids Res (2013) 0.82
Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII. J Immunol (2006) 0.82
Capacity planning for batch and perfusion bioprocesses across multiple biopharmaceutical facilities. Biotechnol Prog (2014) 0.82
Dimensional analysis of MINMOD leads to definition of the disposition index of glucose regulation and improved simulation algorithm. Biomed Eng Online (2006) 0.82
An atypical type II topoisomerase from Mycobacterium smegmatis with positive supercoiling activity. Mol Microbiol (2005) 0.82
Inhibition of DNA gyrase activity by Mycobacterium smegmatis MurI. FEMS Microbiol Lett (2008) 0.81
Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2-a]quinoline-6-carboxylic acid. Bioorg Med Chem (2007) 0.81
Mutations in β' subunit of Escherichia coli RNA polymerase perturb the activator polymerase functional interaction required for promoter clearance. Mol Microbiol (2011) 0.81
Molecular basis for the differential quinolone susceptibility of mycobacterial DNA gyrase. Antimicrob Agents Chemother (2014) 0.81
A transcript cleavage factor of Mycobacterium tuberculosis important for its survival. PLoS One (2011) 0.80
A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease. BMC Syst Biol (2014) 0.80
The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. Cell Immunol (2004) 0.80
Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells. Ann N Y Acad Sci (2003) 0.79
Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity. Arch Biochem Biophys (2012) 0.79
Pathophysiology of catalytic antibodies. Immunol Lett (2005) 0.79
Novel bis(indolyl)hydrazide-hydrazones as potent cytotoxic agents. Bioorg Med Chem Lett (2011) 0.79
The type of responder T-cell has a significant impact in a human in vitro suppression assay. PLoS One (2010) 0.79
A joint association test for multiple SNPs in genetic case-control studies. Genet Epidemiol (2009) 0.79
A monoclonal antibody that inhibits mycobacterial DNA gyrase by a novel mechanism. Nucleic Acids Res (2005) 0.79
Allosteric transition induced by Mg²⁺ ion in a transactivator monitored by SERS. J Phys Chem B (2014) 0.78
Inhibition of Mycobacterium tuberculosis RNA polymerase by binding of a Gre factor homolog to the secondary channel. J Bacteriol (2011) 0.78
Investigation of the age-at-onset heterogeneity in type 1 diabetes through mathematical modeling. Math Biosci (2006) 0.78
Type IA topoisomerase inhibition by clamp closure. FASEB J (2013) 0.78
Generation of a manganese specific restriction endonuclease with nicking activity. Biochemistry (2010) 0.78
Prognostic factors in haemotoxic viper bite: analysis of data from a referral hospital. J Indian Med Assoc (2009) 0.78
A complex of DNA gyrase and RNA polymerase fosters transcription in Mycobacterium smegmatis. Biochem Biophys Res Commun (2006) 0.78
High-throughput assessment of mitochondrial membrane potential in situ using fluorescence resonance energy transfer. Mitochondrion (2002) 0.78
Co-evolution of specific amino acid in sigma 1.2 region and nucleotide base in the discriminator to act as sensors of small molecule effectors of transcription initiation in mycobacteria. Mol Microbiol (2013) 0.78
Bacteriophage Mu C protein is a new member of unusual leucine zipper-HTH class of proteins. Protein Eng Des Sel (2007) 0.77
Binding of two DNA molecules by type II topoisomerases for decatenation. Nucleic Acids Res (2012) 0.77
Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation. Bioorg Med Chem Lett (2007) 0.77
Synthesis & biological evaluation of PYY(3-36) analogs substituted with alanine. Adv Exp Med Biol (2009) 0.77
Silencing of toxic gene expression by Fis. Nucleic Acids Res (2012) 0.77
Endonuclease active site plasticity allows DNA cleavage with diverse alkaline Earth and transition metal ions. ACS Chem Biol (2011) 0.77
Synthesis, antimycobacterial activities and phototoxic evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic acid derivatives. Med Chem (2008) 0.77
Ca(2+) binding to the ExDxD motif regulates the DNA cleavage specificity of a promiscuous endonuclease. Biochemistry (2012) 0.77