Published in J Immunol on November 15, 2006
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Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes. J Endocrinol (2013) 0.77
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Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease. Genet Med (2011) 9.03
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
The Rat Genome Database, update 2007--easing the path from disease to data and back again. Nucleic Acids Res (2006) 4.80
Accuracy and predictive value of classification schemes for ketosis-prone diabetes. Diabetes Care (2006) 4.53
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity (2011) 3.76
An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N Engl J Med (2009) 3.56
Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem (2011) 2.82
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Ketosis-prone diabetes: dissection of a heterogeneous syndrome using an immunogenetic and beta-cell functional classification, prospective analysis, and clinical outcomes. J Clin Endocrinol Metab (2003) 2.58
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes (2004) 2.46
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Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Res (2002) 2.45
The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants. Pediatr Diabetes (2011) 2.44
Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet (2002) 2.44
Physiogenomic resources for rat models of heart, lung and blood disorders. Nat Genet (2006) 2.05
Autoantibodies in diabetes. Diabetes (2005) 1.96
Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays. Genome Biol (2003) 1.94
Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes (2002) 1.89
GAD2 on chromosome 10p12 is a candidate gene for human obesity. PLoS Biol (2003) 1.83
Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease. Blood (2009) 1.80
Quantitative quality control in microarray experiments and the application in data filtering, normalization and false positive rate prediction. Bioinformatics (2003) 1.73
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Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies. Pediatr Diabetes (2010) 1.70
Gene targeting in NOD mouse embryos using zinc-finger nucleases. Diabetes (2013) 1.52
Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. Am J Hum Genet (2006) 1.50
A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2. Diabetes Care (2008) 1.50
Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J Immunol (2008) 1.43
Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY. Diabetes Metab Res Rev (2013) 1.43
Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. J Diabetes Complications (2005) 1.42
Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. J Clin Invest (2010) 1.41
Tissue transglutaminase immunoglobulin isotypes in children with untreated and treated celiac disease. J Pediatr Gastroenterol Nutr (2003) 1.41
TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial. Ann N Y Acad Sci (2006) 1.40
A comparison between SNaPshot, pyrosequencing, and biplex invader SNP genotyping methods: accuracy, cost, and throughput. J Biochem Biophys Methods (2004) 1.38
Genetic analysis of autoimmune type 1 diabetes mellitus in mice. 1991. J Immunol (2014) 1.37
Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37
Impact of genomics on research in the rat. Genome Res (2005) 1.37
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Systematic screening of potential beta-cell imaging agents. Biochem Biophys Res Commun (2004) 1.30
Annual screening detects celiac disease in children with type 1 diabetes. Pediatr Diabetes (2008) 1.26
Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate. J Pharmacol Exp Ther (2007) 1.25
Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility. Nucleic Acids Res (2003) 1.25
Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol (2007) 1.24
Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease. Blood (2008) 1.24
Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data. Genome Res (2004) 1.21
Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. Physiol Genomics (2008) 1.21
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood (2008) 1.19
Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation. PLoS One (2009) 1.19
Three color cDNA microarrays: quantitative assessment through the use of fluorescein-labeled probes. Nucleic Acids Res (2003) 1.18
Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11. Genomics (2004) 1.17
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction. PLoS One (2007) 1.15
Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity. Diabetes (2005) 1.13
Transcriptional characterizations of differences between eutopic and ectopic endometrium. Endocrinology (2005) 1.11
IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy. J Immunol (2012) 1.11
HLA class II alleles specify phenotypes of ketosis-prone diabetes. Diabetes Care (2008) 1.11
Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta. Diabetes Care (2010) 1.10
Utilization of a labeled tracking oligonucleotide for visualization and quality control of spotted 70-mer arrays. BMC Genomics (2004) 1.10
Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the lyon hypertensive rat. Hypertension (2004) 1.09
Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity (2005) 1.09
Early, selective, and marked loss of sympathetic nerves from the islets of BioBreeder diabetic rats. Diabetes (2002) 1.08
Effect of high glucose on gene expression in mesangial cells: upregulation of the thiol pathway is an adaptational response. Physiol Genomics (2004) 1.08
Invited review: the mitochondrion in osteoarthritis. Mitochondrion (2002) 1.07
Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mamm Genome (2009) 1.07
Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of genetic association studies. Am J Epidemiol (2006) 1.07
Immobilized probe and glass surface chemistry as variables in microarray fabrication. BMC Genomics (2004) 1.07
Genetic and perinatal factors as risk for childhood type 1 diabetes. Diabetes Metab Res Rev (2004) 1.06
Non-invasive imaging of beta cell mass: a quantitative analysis. Diabetes Technol Ther (2004) 1.06
Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens. Clin Immunol (2008) 1.06
LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. J Cell Sci (2012) 1.05
Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death. Mol Biol Cell (2011) 1.05
Genetic determinants of obesity-related lipid traits. J Lipid Res (2004) 1.04
Tools and strategies for physiological genomics: the Rat Genome Database. Physiol Genomics (2005) 1.04
Dynamic perifusion to maintain and assess isolated pancreatic islets. Diabetes Technol Ther (2002) 1.04
Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. J Autoimmun (2012) 1.03
Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. Am J Physiol Cell Physiol (2006) 1.03
A high prevalence of organ-specific autoimmunity in patients with bipolar disorder. Biol Psychiatry (2004) 1.03
The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression. Eur J Immunol (2009) 1.02
PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer. J Cell Sci (2011) 1.00
Type 1 diabetes in Swedish bank voles (Clethrionomys glareolus): signs of disease in both colonized and wild cyclic populations at peak density. Ann N Y Acad Sci (2003) 1.00
Factor V Leiden: a genetic risk factor for thrombotic microangiopathy in patients with normal von Willebrand factor-cleaving protease activity. Blood (2002) 1.00
TAPPA: topological analysis of pathway phenotype association. Bioinformatics (2007) 0.99
Comparative genomics for detecting human disease genes. Adv Genet (2008) 0.98