Published in J Clin Endocrinol Metab on September 02, 2008
Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Sci Transl Med (2013) 4.15
Acute effects of gastric bypass versus gastric restrictive surgery on beta-cell function and insulinotropic hormones in severely obese patients with type 2 diabetes. Int J Obes (Lond) (2009) 2.70
Metabolic effects of bariatric surgery in patients with moderate obesity and type 2 diabetes: analysis of a randomized control trial comparing surgery with intensive medical treatment. Diabetes Care (2013) 1.83
Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of weight lost. J Gastrointest Surg (2009) 1.56
Bariatric surgery for type 2 diabetes: weighing the impact for obese patients. Cleve Clin J Med (2010) 1.54
Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery. J Diabetes (2010) 1.46
Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. PLoS One (2010) 1.38
Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials. Can J Surg (2013) 1.15
Diabetes: have we got it all wrong? Hyperinsulinism as the culprit: surgery provides the evidence. Diabetes Care (2012) 1.12
Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat. Am J Physiol Gastrointest Liver Physiol (2010) 1.07
Severe obesity: evidence for a deranged metabolic program in skeletal muscle? Exerc Sport Sci Rev (2012) 0.99
Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/Jng. J Endocrinol (2009) 0.96
Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment. Am J Physiol Regul Integr Comp Physiol (2010) 0.95
Gastric bypass surgery is associated with near-normal insulin suppression of lipolysis in nondiabetic individuals. Am J Physiol Endocrinol Metab (2011) 0.90
Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report. Diabetes Metab Syndr Obes (2010) 0.89
Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity. J Clin Invest (2014) 0.88
Transient receptor potential channels as targets for phytochemicals. ACS Chem Neurosci (2014) 0.88
Bariatric surgery in old age: a comparative study of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in an Asia centre of excellence. J Biomed Res (2015) 0.87
Is there a metabolic program in the skeletal muscle of obese individuals? J Obes (2011) 0.87
Metformin Improves Insulin Signaling in Obese Rats via Reduced IKKbeta Action in a Fiber-Type Specific Manner. J Obes (2010) 0.86
What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant? Curr Opin Lipidol (2013) 0.86
AICAR inhibits ceramide biosynthesis in skeletal muscle. Diabetol Metab Syndr (2012) 0.84
Dual mechanism for type-2 diabetes resolution after Roux-en-Y gastric bypass. Am Surg (2009) 0.81
The effect of duodenal-jejunal bypass on glucose-dependent insulinotropic polypeptide secretion in Wistar rats. Obes Surg (2010) 0.81
Tissue-specific effects of bariatric surgery including mitochondrial function. J Obes (2011) 0.79
Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. Obesity (Silver Spring) (2015) 0.79
Bariatric surgery and T2DM improvement mechanisms: a mathematical model. Theor Biol Med Model (2012) 0.78
The effects of an amino acid supplement on glucose homeostasis, inflammatory markers, and incretins after laparoscopic gastric bypass. J Am Coll Surg (2011) 0.78
Restoration of glycemic control in patients with type 2 diabetes mellitus after bariatric surgery is associated with reduction in microparticles. Surg Obes Relat Dis (2011) 0.76
A prospective evaluation of the influence of three bariatric procedures on insulin resistance improvement. Should the extent of undiluted bile transit be considered a key postoperative factor altering glucose metabolism? Wideochir Inne Tech Maloinwazyjne (2015) 0.75
The Impact of Bariatric Surgery on Type 2 Diabetes Mellitus and the Management of Hypoglycemic Events. Front Endocrinol (Lausanne) (2017) 0.75
Bariatric surgery: a systematic review and meta-analysis. JAMA (2004) 23.34
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med (2001) 16.51
Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. JAMA (2008) 13.69
IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med (2005) 12.07
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science (2001) 11.56
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med (2005) 10.88
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem (2002) 9.76
Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw (2006) 7.19
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes (2002) 7.17
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature (1998) 6.69
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes (2006) 4.95
Prevention of fat-induced insulin resistance by salicylate. J Clin Invest (2001) 4.74
Assessment of insulin sensitivity in vivo. Endocr Rev (1985) 4.21
Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes. J Clin Endocrinol Metab (2008) 4.19
Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex. J Biol Chem (2002) 3.83
The relation of body fat mass and distribution to markers of chronic inflammation. Int J Obes Relat Metab Disord (2001) 3.39
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects. J Clin Invest (1988) 2.86
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension (2006) 2.42
Is type 2 diabetes an operable intestinal disease? A provocative yet reasonable hypothesis. Diabetes Care (2008) 2.10
Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes (2002) 2.06
Body composition, dietary intake, and energy expenditure after laparoscopic Roux-en-Y gastric bypass and laparoscopic vertical banded gastroplasty: a randomized clinical trial. Ann Surg (2006) 1.97
AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun (2004) 1.89
Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites. J Appl Physiol (1985) (2005) 1.88
Macrophage-secreted factors induce adipocyte inflammation and insulin resistance. Biochem Biophys Res Commun (2006) 1.74
Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner. J Biol Chem (2004) 1.69
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest (1992) 1.69
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells. FASEB J (2001) 1.40
Suppression of nuclear factor-kappaB and stimulation of inhibitor kappaB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese. J Clin Endocrinol Metab (2001) 1.37
Protein kinase C and lipid-induced insulin resistance in skeletal muscle. Ann N Y Acad Sci (2002) 1.29
Effect of weight loss on muscle lipid content in morbidly obese subjects. Am J Physiol Endocrinol Metab (2002) 1.27
NF-kappaB: a stress-regulated switch for cell survival. Antioxid Redox Signal (2006) 1.19
Is type II diabetes mellitus (NIDDM) a surgical disease? Ann Surg (1992) 1.17
Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling. Am J Physiol Endocrinol Metab (2007) 1.15
Food intake patterns of gastric bypass patients. J Am Diet Assoc (1982) 1.14
Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells. FASEB J (2007) 1.13
Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance. Am J Physiol Endocrinol Metab (2006) 1.11
Low-grade inflammation and the metabolic syndrome in children and adolescents. Curr Opin Lipidol (2008) 1.10
Skeletal muscle GLUT4 protein concentration and aging in humans. Diabetes (1995) 1.06
Modulation of the inflammatory response in cardiovascular disease. Hypertension (2004) 1.06
Why Does the Gastric Bypass Control Type 2 Diabetes Mellitus? Obes Surg (1992) 0.97
Dephosphorylation increases insulin-stimulated receptor kinase activity in skeletal muscle of obese Zucker rats. Mol Cell Biochem (1999) 0.93
Effect of moderate obesity on glucose transport in human muscle. Horm Metab Res (1994) 0.85
Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med (2009) 13.91
Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med (2009) 8.06
Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med (2002) 7.34
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest (2009) 5.66
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell (2013) 3.83
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care (2009) 3.69
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery. Surg Obes Relat Dis (2007) 3.67
Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA (2013) 3.57
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab (2005) 3.47
Effects of the amount of exercise on body weight, body composition, and measures of central obesity: STRRIDE--a randomized controlled study. Arch Intern Med (2004) 3.30
Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol (1985) (2003) 3.18
Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics (2013) 2.44
Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol (1985) (2005) 2.38
Muscle fiber type is associated with obesity and weight loss. Am J Physiol Endocrinol Metab (2002) 2.38
Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise - STRRIDE-AT/RT). Am J Cardiol (2011) 2.28
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem (2002) 2.25
Exercise training amount and intensity effects on metabolic syndrome (from Studies of a Targeted Risk Reduction Intervention through Defined Exercise). Am J Cardiol (2007) 2.14
Skeletal muscle lipid metabolism with obesity. Am J Physiol Endocrinol Metab (2002) 2.13
Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol (1985) (2007) 2.11
Prevalence of alcohol use disorders before and after bariatric surgery. JAMA (2012) 2.02
Effects of exercise training intensity on pancreatic beta-cell function. Diabetes Care (2009) 1.93
Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. Am J Physiol Endocrinol Metab (2011) 1.91
Renal cell carcinoma with renal vein and inferior vena caval involvement: clinicopathological features, surgical techniques and outcomes. J Urol (2005) 1.89
Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance. Am J Physiol Endocrinol Metab (2007) 1.81
Antibodies to MHC class I induce autoimmunity: role in the pathogenesis of chronic rejection. J Immunol (2009) 1.74
Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells. Diabetes (2002) 1.73
Baseline characteristics of participants in the Longitudinal Assessment of Bariatric Surgery-2 (LABS-2) study. Surg Obes Relat Dis (2013) 1.70
GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle. Physiol Genomics (2006) 1.67
Relationship between surgeon volume and adverse outcomes after RYGB in Longitudinal Assessment of Bariatric Surgery (LABS) study. Surg Obes Relat Dis (2009) 1.63
Mitochondrial respiratory capacity and content are normal in young insulin-resistant obese humans. Diabetes (2013) 1.55
Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. Diabetes (2008) 1.51
Body mass index and outcomes in critically injured blunt trauma patients: weighing the impact. J Am Coll Surg (2007) 1.49
Ethnic differences in adiponectin levels. Metabolism (2004) 1.45
Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance. Diabetes (2003) 1.42
Relationship of body mass index with demographic and clinical characteristics in the Longitudinal Assessment of Bariatric Surgery (LABS). Surg Obes Relat Dis (2008) 1.41
Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects. Diabetes (2002) 1.40
Scientific data from clinical trials: investigators' responsibilities and rights. Surg Endosc (2002) 1.39
Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle. Mol Cell (2005) 1.39
The ASBS Bariatric Surgery Centers of Excellence program: a blueprint for quality improvement. Surg Obes Relat Dis (2006) 1.37
Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability. Cancer Res (2002) 1.36
Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. Am J Physiol Cell Physiol (2005) 1.36
Intramuscular lipid metabolism, insulin action, and obesity. IUBMB Life (2009) 1.33
Effects of exercise training amount and intensity on peak oxygen consumption in middle-age men and women at risk for cardiovascular disease. Chest (2005) 1.30
Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function. Endocrinology (2006) 1.29
Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise. Am J Physiol Endocrinol Metab (2008) 1.29
Effect of weight loss on muscle lipid content in morbidly obese subjects. Am J Physiol Endocrinol Metab (2002) 1.27
Gender and racial differences in lipoprotein subclass distributions: the STRRIDE study. Atherosclerosis (2004) 1.26
The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening. AIDS (2010) 1.25
Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. Am J Physiol Endocrinol Metab (2002) 1.24
Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med (2011) 1.24
Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation. J Appl Physiol (1985) (2009) 1.21
Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. Am J Physiol Cell Physiol (2006) 1.21
Impaired plasma fatty acid oxidation in extremely obese women. Am J Physiol Endocrinol Metab (2004) 1.21
Adiponectin is not altered with exercise training despite enhanced insulin action. Am J Physiol Endocrinol Metab (2002) 1.21
Pre- to postoperative changes in physical activity: report from the longitudinal assessment of bariatric surgery-2 (LABS-2). Surg Obes Relat Dis (2011) 1.19
Exercise, abdominal obesity, skeletal muscle, and metabolic risk: evidence for a dose response. Obesity (Silver Spring) (2009) 1.19
Proteome analysis of skeletal muscle from obese and morbidly obese women. Diabetes (2005) 1.18
Modest exercise prevents the progressive disease associated with physical inactivity. Exerc Sport Sci Rev (2007) 1.16
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. Diabetes (2010) 1.15
Skeletal muscle fat oxidation is increased in African-American and white women after 10 days of endurance exercise training. Obesity (Silver Spring) (2006) 1.14
The molecular mechanism linking muscle fat accumulation to insulin resistance. Proc Nutr Soc (2004) 1.14
GLP-1 response to a mixed meal: what happens 10 years after Roux-en-Y gastric bypass (RYGB)? Obes Surg (2012) 1.13
Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance. Am J Physiol Endocrinol Metab (2007) 1.12
Diabetes: have we got it all wrong? Hyperinsulinism as the culprit: surgery provides the evidence. Diabetes Care (2012) 1.12
Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes. J Clin Endocrinol Metab (2011) 1.10