Published in Autophagy on November 20, 2008
Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo. J Virol (2010) 1.38
Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. J Clin Invest (2013) 1.17
Autophagy in pancreatic cancer pathogenesis and treatment. Am J Cancer Res (2012) 1.07
Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis. Front Physiol (2012) 0.93
Central role of neutrophil in the pathogenesis of severe acute pancreatitis. J Cell Mol Med (2015) 0.85
Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotype. Am J Physiol Gastrointest Liver Physiol (2010) 0.81
Ascitic fluid and serum from rats with acute pancreatitis injure rat pancreatic tissues and alter the expression of heat shock protein 60. Cell Stress Chaperones (2010) 0.79
Down-regulation of HSP60 expression by RNAi increases lipopolysaccharide- and cerulein-induced damages on isolated rat pancreatic tissues. Cell Stress Chaperones (2010) 0.79
Interleukin-1β induces autophagy by affecting calcium homeostasis and trypsinogen activation in pancreatic acinar cells. Int J Clin Exp Pathol (2014) 0.78
Heat shock proteins and autophagy in rats with cerulein-induced acute pancreatitis. Gut Liver (2011) 0.77
Extensive molecular analysis suggested the strong genetic heterogeneity of idiopathic chronic pancreatitis. Mol Med (2016) 0.76
Hydrogen sulphide exacerbates acute pancreatitis by over-activating autophagy via AMPK/mTOR pathway. J Cell Mol Med (2016) 0.76
Long-lasting effect of infant rats endotoxemia on heat shock protein 60 in the pancreatic acinar cells: involvement of toll-like receptor 4. Int J Inflam (2012) 0.75
The fusion of autophagosome with lysosome is impaired in L-arginine-induced acute pancreatitis. Int J Clin Exp Pathol (2015) 0.75
Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis. Saudi J Gastroenterol (2015) 0.75
Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats. Mediators Inflamm (2016) 0.75
Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol. Leukemia (2016) 0.75
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development (2002) 2.59
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest (2011) 2.13
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J Cell Biol (2008) 1.85
Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest. Am J Physiol Heart Circ Physiol (2009) 1.66
Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites. Nucleic Acids Res (2002) 1.54
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nat Commun (2012) 1.36
Methyl-beta-cyclodextrin improves fertilizing ability of C57BL/6 mouse sperm after freezing and thawing by facilitating cholesterol efflux from the cells. Biol Reprod (2007) 1.34
Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice. Dev Dyn (2009) 1.30
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev Growth Differ (2005) 1.28
LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice. Biol Reprod (2006) 1.27
Region-specific gastrointestinal Hox code during murine embryonal gut development. Dev Growth Differ (2002) 1.19
Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells. Cell Rep (2013) 1.12
Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells. Blood (2002) 1.09
Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice. Hum Mol Genet (2006) 1.09
Abnormal migration and distribution of neural crest cells in Pax6 heterozygous mutant eye, a model for human eye diseases. Genes Cells (2006) 1.06
A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc. Genetics (2005) 1.06
Enhanced trypsin activity in pancreatic acinar cells deficient for serine protease inhibitor kazal type 3. Pancreas (2006) 1.03
Expression of Hqk encoding a KH RNA binding protein is altered in human glioma. Jpn J Cancer Res (2002) 1.03
HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer. Am J Pathol (2009) 1.01
International Gene Trap Project: towards gene-driven saturation mutagenesis in mice. Curr Pharm Biotechnol (2009) 1.01
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Mol Cell Biol (2010) 0.95
Proteome profiling reveals gender differences in the composition of human serum. Proteomics (2010) 0.95
Rad18 is required for long-term maintenance of spermatogenesis in mouse testes. Mech Dev (2008) 0.93
Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene. Biochem Biophys Res Commun (2005) 0.92
Essential roles of androgen signaling in Wolffian duct stabilization and epididymal cell differentiation. Endocrinology (2011) 0.92
Comparative analysis of right element mutant lox sites on recombination efficiency in embryonic stem cells. BMC Biotechnol (2010) 0.90
Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells. Proc Natl Acad Sci U S A (2014) 0.90
Meltrin beta expressed in cardiac neural crest cells is required for ventricular septum formation of the heart. Dev Biol (2006) 0.90
Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases. Exp Anim (2011) 0.90
Establishment of an efficient BAC transgenesis protocol and its application to functional characterization of the mouse Brachyury locus. Exp Anim (2004) 0.89
Role of ornithine decarboxylase antizyme inhibitor in vivo. Genes Cells (2008) 0.89
Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins. Proc Natl Acad Sci U S A (2009) 0.88
Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet (2013) 0.88
Expression pattern of serine protease inhibitor kazal type 3 (Spink3) during mouse embryonic development. Histochem Cell Biol (2008) 0.88
Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy. Hum Mol Genet (2003) 0.88
Relationship of strain-dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression. Lab Invest (2010) 0.87
IGSF4 is a novel TCR ζ-chain-interacting protein that enhances TCR-mediated signaling. J Exp Med (2011) 0.87
Immunization in familial amyloidotic polyneuropathy: counteracting deposition by immunization with a Y78F TTR mutant. Lab Invest (2006) 0.85
The floor plate is sufficient for development of the sclerotome and spine without the notochord. Mech Dev (2010) 0.85
Inconsistency between hepatic expression and serum concentration of transthyretin in mice humanized at the transthyretin locus. Genes Cells (2008) 0.84
Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene. Biochem Biophys Res Commun (2009) 0.83
NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. Nucleic Acids Res (2011) 0.83
Reduced bone morphogenetic protein receptor type 1A signaling in neural-crest-derived cells causes facial dysmorphism. Dis Model Mech (2012) 0.83
Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain. Mamm Genome (2008) 0.82
Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque. Biochem Biophys Res Commun (2007) 0.82
The Skt gene, required for anorectal development, is a candidate for a molecular marker of the cloacal plate. Pediatr Surg Int (2011) 0.82
Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells. Biochem Biophys Res Commun (2012) 0.81
The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic stem cells and mature lineage progenitors by protecting from genotoxic stress. Cancer Sci (2011) 0.81
Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotype. Am J Physiol Gastrointest Liver Physiol (2010) 0.81
Database for exchangeable gene trap clones: pathway and gene ontology analysis of exchangeable gene trap clone mouse lines. Dev Growth Differ (2014) 0.81
Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet. Exp Anim (2010) 0.81
Negative selection with the Diphtheria toxin A fragment gene improves frequency of Cre-mediated cassette exchange in ES cells. J Biochem (2006) 0.81
Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates. BMC Biol (2014) 0.80
Draxin, an axon guidance protein, affects chick trunk neural crest migration. Dev Growth Differ (2009) 0.80
Changes in liver gene expression of Azin1 knock-out mice. Z Naturforsch C (2010) 0.80
Effect of the intestinal flora on amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy. Exp Anim (2002) 0.79
Enhanced expression of human cDNA by phosphoglycerate kinase promoter-puromycin cassette in the mouse transthyretin locus. Transgenic Res (2010) 0.79
Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo. Amyloid (2004) 0.79
Impaired expression of importin/karyopherin beta1 leads to post-implantation lethality. Biochem Biophys Res Commun (2006) 0.78
Inhibitory effects of cigarette smoke extract on neural crest migration occur through suppression of R-spondin1 expression via aryl hydrocarbon receptor. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.78
Multi-modal effects of BMP signaling on Nodal expression in the lateral plate mesoderm during left-right axis formation in the chick embryo. Dev Biol (2012) 0.78
Effect of low-molecular weight trypsin inhibitor, nafamostat mesilate, on trypsin activity using the pancreatic acinar cells. Pancreas (2009) 0.75
Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome (2013) 0.75
Strain-dependency of chromosomal abnormalities in lymphomas developed in E(mu)-myc transgenic mice. Jpn J Cancer Res (2002) 0.75
Cloning and expression analysis of a murine novel gene, Ayu17-449. Yi Chuan Xue Bao (2006) 0.75
Survey of live laboratory animals reared in Japan (2009). Exp Anim (2010) 0.75
Mammalian mutant resources for therapeutic challenges. Curr Pharm Biotechnol (2009) 0.75