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1
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SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
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Cell Metab
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2008
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6.60
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2
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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.
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Cancer Cell
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2005
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5.47
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3
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PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.
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Oncogene
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2005
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2.77
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4
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Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies.
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J Natl Cancer Inst
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2006
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1.83
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5
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Combined metabolomic and proteomic analysis of human atrial fibrillation.
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J Am Coll Cardiol
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2008
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1.38
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6
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Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice.
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Am J Physiol Heart Circ Physiol
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2004
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1.34
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7
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Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
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Hum Mol Genet
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2010
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1.33
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8
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Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
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Cancer Res
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2006
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1.29
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9
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Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism.
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Arterioscler Thromb Vasc Biol
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2005
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1.23
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10
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Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.
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Cancer Res
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2002
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1.21
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11
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Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data.
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PLoS One
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2013
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1.15
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12
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Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts.
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J Oncol
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2010
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1.14
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13
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Glucose homeostasis across human airway epithelial cell monolayers: role of diffusion, transport and metabolism.
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Pflugers Arch
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2008
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1.12
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14
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Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.
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Cancer Chemother Pharmacol
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2007
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1.11
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15
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Loss of PKC-delta alters cardiac metabolism.
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Am J Physiol Heart Circ Physiol
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2004
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1.10
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16
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Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.
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Cancer Res
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2010
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1.05
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17
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A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe.
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Proteomics
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2006
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1.04
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18
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Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.
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Circ Res
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2008
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1.00
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19
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Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure.
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J Mol Cell Cardiol
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2010
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0.99
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20
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Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta.
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Circ Res
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2004
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0.92
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21
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Vascular proteomics: linking proteomic and metabolomic changes.
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Proteomics
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2004
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0.91
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22
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Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.
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Cancer Res
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2011
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0.89
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23
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Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy.
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Clin Cancer Res
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2005
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0.86
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24
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Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate.
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Ann N Y Acad Sci
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2006
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0.82
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25
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Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
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BMC Cancer
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2011
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0.81
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26
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Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.
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BMC Res Notes
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2012
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0.79
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27
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Microdissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis.
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BMC Infect Dis
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2004
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0.79
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28
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Molecular and metabolic consequences following E6 transfection in an isogenic ovarian cell line (A2780) pair.
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Cell Physiol Biochem
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2013
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0.79
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