Published in Pflugers Arch on September 10, 2008
Development of Pneumonia Due to Alveolar Glucose Levels in Systemic Hyperglycemia | NCT03577964
Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J Clin Invest (2014) 1.42
Glucose depletion in the airway surface liquid is essential for sterility of the airways. PLoS One (2011) 1.26
Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose. Thorax (2013) 1.12
Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth. PLoS One (2013) 0.94
Proinflammatory mediators disrupt glucose homeostasis in airway surface liquid. J Immunol (2012) 0.93
Pulmonary function reduction in diabetes with and without chronic obstructive pulmonary disease. Diabetes Care (2013) 0.89
Bitter and sweet taste receptors in the respiratory epithelium in health and disease. J Mol Med (Berl) (2014) 0.87
Taste receptors in innate immunity. Cell Mol Life Sci (2014) 0.86
Role of glucose in the expression of Cryptococcus neoformans antiphagocytic protein 1, App1. Eukaryot Cell (2011) 0.84
Glucose transporter/T1R3-expressing cells in rat tracheal epithelium. J Anat (2012) 0.83
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. Cell Mol Life Sci (2014) 0.82
Bacterial respiratory tract infections are promoted by systemic hyperglycemia after severe burn injury in pediatric patients. Burns (2013) 0.81
The Role of Bitter and Sweet Taste Receptors in Upper Airway Immunity. Curr Allergy Asthma Rep (2015) 0.78
Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth. J Cell Mol Med (2016) 0.78
Increased airway glucose increases airway bacterial load in hyperglycaemia. Sci Rep (2016) 0.77
A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration. Biochem J (2014) 0.77
SGLT1 activity in lung alveolar cells of diabetic rats modulates airway surface liquid glucose concentration and bacterial proliferation. Sci Rep (2016) 0.77
Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence. Sci Rep (2016) 0.76
Taste Receptors Mediate Sinonasal Immunity and Respiratory Disease. Int J Mol Sci (2017) 0.75
A role for airway taste receptor modulation in the treatment of upper respiratory infections. Expert Rev Respir Med (2016) 0.75
Pulmonary Predictors of Incident Diabetes in Smokers. Chronic Obstr Pulm Dis (2016) 0.75
Molecules implicated in glucose homeostasis are differentially expressed in the trachea of lean and obese Zucker rats. Eur J Histochem (2016) 0.75
Taste Receptors: Regulators of Sinonasal Innate Immunity. Laryngoscope Investig Otolaryngol (2016) 0.75
Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells. Sci Signal (2017) 0.75
Passage of molecules through capillary wals. Physiol Rev (1953) 12.78
Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability. Am J Physiol (1951) 10.63
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch (2003) 3.81
The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J (2000) 2.59
Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures. J Physiol (1988) 2.10
Luminal glucose concentrations in the gut under normal conditions. Am J Physiol (1990) 1.85
Monocarboxylate transport in erythrocytes. J Membr Biol (1982) 1.81
Glucose in bronchial aspirates increases the risk of respiratory MRSA in intubated patients. Thorax (2005) 1.78
Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis. J Appl Physiol (1985) (2007) 1.62
On the coupling of membrane digestion with intestinal absorption of sugars and amino acids. Am J Physiol (1993) 1.46
Lung epithelial cell lines in coculture with human pulmonary microvascular endothelial cells: development of an alveolo-capillary barrier in vitro. Lab Invest (2004) 1.41
The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147. Am J Pathol (2002) 1.30
A study of some effects of phlorizon on the metabolism of kidney tissue in vitro. J Biol Chem (1956) 1.28
Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells. J Physiol (2005) 1.26
cAMP-induced changes of apical membrane potentials of confluent H441 monolayers. Am J Physiol Lung Cell Mol Physiol (2003) 1.25
Lung cancer: a comparative study of metabolism related protein expression in cancer cells and tumor associated stroma. Cancer Biol Ther (2007) 1.18
Determination of synthesis, recycling and body mass of glucose in rats and rabbits in vivo 3H-and 14C-labelled glucose. Biochem J (1974) 1.17
Effect of hyperglycaemia on glucose concentration of human nasal secretions. Clin Sci (Lond) (2004) 1.16
Development of intercellular junctions in the pulmonary epithelium of the foetal lamb. J Cell Sci (1978) 1.07
cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1. Am J Physiol Lung Cell Mol Physiol (2004) 1.06
Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monolayers. J Pharm Sci (1994) 1.05
Stress and glucocorticoid inhibit apical GLUT2-trafficking and intestinal glucose absorption in rat small intestine. J Physiol (2004) 1.04
Isolation and air-liquid interface culture of human large airway and bronchiolar epithelial cells. J Cyst Fibros (2004) 1.02
Apical and basolateral localisation of GLUT2 transporters in human lung epithelial cells. Pflugers Arch (2008) 1.01
Pulmonary glucose transport in the fetal sheep. J Physiol (1989) 0.98
Glucose transport and equilibrium across alveolar-airway barrier of rat. Am J Physiol (1996) 0.96
Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells. Br J Pharmacol (2007) 0.95
Metabolic response to carbon monoxide by isolated rat lungs. Am J Physiol (1976) 0.92
The cell biology of ion pumps: sorting and regulation. Eur J Cell Biol (2000) 0.90
Characterization of ion and fluid transport in human bronchioles. Am J Respir Cell Mol Biol (2002) 0.88
High glucose concentration in isotonic media alters caco-2 cell permeability. AAPS PharmSci (2003) 0.87
Effect of changes in paracellular permeability on airspace liquid clearance: role of glucose transport. Am J Physiol (1996) 0.87
Basal-lateral transport and transcellular flux of methyl alpha-D-glucoside across LLC-PK1 renal epithelial cells. Biochim Biophys Acta (1986) 0.86
Cultured retinal neuronal cells and Müller cells both show net production of lactate. Neurochem Int (2004) 0.86
Effect of hypoxia on incorporation of glucose carbons into lipids by isolated rat lung. Am J Physiol (1974) 0.85
D- and L-glucose transport across the pulmonary epithelium. J Appl Physiol Respir Environ Exerc Physiol (1984) 0.84
Ultrastructure of airway epithelial cell membranes among patients with cystic fibrosis. Hum Pathol (1990) 0.82
Monocarboxylate transporter 1 (MCT1) plays a direct role in short-chain fatty acids absorption in caprine rumen. J Physiol (2006) 0.82
Effects of phloretin and dextran-linked phloretin on pancreatic islet metabolism and insulin release. Biochim Biophys Acta (1978) 0.81
Pulmonary epithelial permeability in bronchiectasis. Br J Dis Chest (1988) 0.80
A review of metabolism of labeled glucoses for use in measuring glucose recycling. J Dairy Sci (1990) 0.77
Determination of monosaccharides and sugar alcohols in tissues from diabetic rats by high-performance liquid chromatography with pulsed amperometric detection. Anal Biochem (1992) 0.76
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab (2008) 6.60
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell (2005) 5.47
Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum. Lancet (2006) 2.96
PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene (2005) 2.77
Making medicines evergreen. BMJ (2012) 2.74
A novel and accurate diagnostic test for human African trypanosomiasis. Lancet (2004) 2.22
Structural basis for complement factor H linked age-related macular degeneration. J Exp Med (2007) 2.02
Sugar absorption in the intestine: the role of GLUT2. Annu Rev Nutr (2008) 1.88
Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies. J Natl Cancer Inst (2006) 1.83
Factors determining the appearance of glucose in upper and lower respiratory tract secretions. Intensive Care Med (2003) 1.71
Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis. J Appl Physiol (1985) (2007) 1.62
Combined metabolomic and proteomic analysis of human atrial fibrillation. J Am Coll Cardiol (2008) 1.38
Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice. Am J Physiol Heart Circ Physiol (2004) 1.34
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. Hum Mol Genet (2010) 1.33
Airway glucose concentrations and effect on growth of respiratory pathogens in cystic fibrosis. J Cyst Fibros (2006) 1.30
Identification of a second lipopolysaccharide in Porphyromonas gingivalis W50. J Bacteriol (2008) 1.30
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models. Cancer Res (2006) 1.29
Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells. J Physiol (2005) 1.26
Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism. Arterioscler Thromb Vasc Biol (2005) 1.23
Clinical importance of cystic fibrosis-related diabetes. J Cyst Fibros (2004) 1.18
Effect of hyperglycaemia on glucose concentration of human nasal secretions. Clin Sci (Lond) (2004) 1.16
Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data. PLoS One (2013) 1.15
Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. J Oncol (2010) 1.14
Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose. Thorax (2013) 1.12
Apical GLUT2 and Cav1.3: regulation of rat intestinal glucose and calcium absorption. J Physiol (2007) 1.12
Clinical review: Biomarkers of acute kidney injury: where are we now? Crit Care (2012) 1.12
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies. Cancer Chemother Pharmacol (2007) 1.11
Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue. PLoS Negl Trop Dis (2010) 1.11
Loss of PKC-delta alters cardiac metabolism. Am J Physiol Heart Circ Physiol (2004) 1.10
Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. Cancer Res (2010) 1.05
Stress and glucocorticoid inhibit apical GLUT2-trafficking and intestinal glucose absorption in rat small intestine. J Physiol (2004) 1.04
A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe. Proteomics (2006) 1.04
Temperature-dependent modulation of Porphyromonas gingivalis lipid A structure and interaction with the innate host defenses. Infect Immun (2011) 1.02
Sweet talk: insights into the nature and importance of glucose transport in lung epithelium. Eur Respir J (2012) 1.02
Apical and basolateral localisation of GLUT2 transporters in human lung epithelial cells. Pflugers Arch (2008) 1.01
Serum alpha 2-HS glycoprotein predicts survival in patients with glioblastoma. Clin Chem (2008) 1.01
Estrogen and progesterone regulate alpha, beta, and gammaENaC subunit mRNA levels in female rat kidney. Kidney Int (2004) 1.01
The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes. J Cell Sci (2013) 1.01
Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice. Circ Res (2008) 1.00
Hyperglycaemia and pulmonary infection. Proc Nutr Soc (2006) 0.99
Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure. J Mol Cell Cardiol (2010) 0.99
Relationship between glycosylated haemoglobin and mean plasma glucose concentration in cystic fibrosis. J Cyst Fibros (2005) 0.96
Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers. J Biol Chem (2005) 0.94
Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth. PLoS One (2013) 0.94
Proinflammatory mediators disrupt glucose homeostasis in airway surface liquid. J Immunol (2012) 0.93
Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta. Circ Res (2004) 0.92
Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na⁺ transport in response to apical fluid volume expansion in human H441 airway epithelial cells. Pflugers Arch (2011) 0.91
AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells. J Physiol (2008) 0.91
Vascular proteomics: linking proteomic and metabolomic changes. Proteomics (2004) 0.91
Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers. Cancer Res (2011) 0.89
Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.89
COPD-related bronchiectasis; independent impact on disease course and outcomes. COPD (2014) 0.87
Glycoform composition profiling of O-glycopeptides derived from human serum IgA1 by matrix-assisted laser desorption ionization-time of flight-mass spectrometry. Anal Biochem (2004) 0.86
Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy. Clin Cancer Res (2005) 0.86
Proteomic analysis of fast and slow muscles from normal and kyphoscoliotic mice using protein arrays, 2-DE and MS. Proteomics (2006) 0.83
Proteomic dataset of mouse aortic smooth muscle cells. Proteomics (2005) 0.83
Evaluation of an integrated strategy for proteomic profiling of skeletal muscle. Proteomics (2004) 0.83
Functional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing. J Biomed Graph Comput (2013) 0.83
Blood glucose: of emerging importance in COPD exacerbations. Thorax (2009) 0.82
Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate. Ann N Y Acad Sci (2006) 0.82
Immunoglobulin A multiple myeloma presenting with Henoch-Schönlein purpura associated with reduced sialylation of IgA1. Br J Haematol (2003) 0.82
Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. Cell Mol Life Sci (2014) 0.82
Integrated membrane protein analysis of mature and embryonic stem cell-derived smooth muscle cells using a novel combination of CyDye/biotin labeling. Mol Cell Proteomics (2007) 0.82
Using midazolam to monitor changes in hepatic drug metabolism in critically ill patients. Intensive Care Med (2009) 0.81
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas. BMC Cancer (2011) 0.81
Safety of Metformin in Patients with Chronic Obstructive Pulmonary Disease and Type 2 Diabetes Mellitus. COPD (2014) 0.80
Microdissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis. BMC Infect Dis (2004) 0.79
Phase II study of tight glycaemic control in COPD patients with exacerbations admitted to the acute medical unit. BMJ Open (2011) 0.79
Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy. BMC Res Notes (2012) 0.79
TGF-beta activates ERK5 in human renal epithelial cells. Biochem Biophys Res Commun (2008) 0.79
Molecular and metabolic consequences following E6 transfection in an isogenic ovarian cell line (A2780) pair. Cell Physiol Biochem (2013) 0.79
Renohepatic crosstalk: does acute kidney injury cause liver dysfunction? Nephrol Dial Transplant (2013) 0.78
Hyperglycaemia in the acute care setting. Clin Med (2012) 0.78
Role played by disabled-2 in albumin induced MAP Kinase signalling. Biochem Biophys Res Commun (2007) 0.78
Proteomic dataset of Sca-1+ progenitor cells. Proteomics (2005) 0.77
End-of-life care in patients with end-stage renal disease. Nephrol Dial Transplant (2012) 0.76
Understanding and managing medication in elderly people. Best Pract Res Clin Obstet Gynaecol (2013) 0.76
Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. Crit Care Res Pract (2013) 0.75
Safety of metformin in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus. COPD (2015) 0.75
Using tramadol to measure CYP2D6 metabolism in critically ill adults. Intensive Care Med (2014) 0.75
A double-blind, randomized, placebo-controlled study to explore the efficacy of a dietary plant-derived polysaccharide supplement in patients with rheumatoid arthritis. Rheumatology (Oxford) (2011) 0.75