Published in Curr Drug Targets on September 01, 2008
Antibacterial activities of selected Cameroonian spices and their synergistic effects with antibiotics against multidrug-resistant phenotypes. BMC Complement Altern Med (2011) 1.35
PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. PLoS Comput Biol (2009) 1.35
Assembly and transport mechanism of tripartite drug efflux systems. Biochim Biophys Acta (2009) 1.31
Functional rotation of the transporter AcrB: insights into drug extrusion from simulations. PLoS Comput Biol (2010) 1.15
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli. J Biol Eng (2009) 1.05
Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Mol Microbiol (2013) 0.95
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa. Front Microbiol (2015) 0.94
Study of the multidrug membrane transporter of single living Pseudomonas aeruginosa cells using size-dependent plasmonic nanoparticle optical probes. Biochemistry (2010) 0.94
Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3. J Biol Chem (2011) 0.92
Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner. J Biol Chem (2010) 0.86
pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli: protection during its passage and eventual colonization of the colon. PLoS One (2009) 0.83
An inducible fusaric acid tripartite efflux pump contributes to the fusaric acid resistance in Stenotrophomonas maltophilia. PLoS One (2012) 0.80
Design and study of the efflux function of the EGFP fused MexAB-OprM membrane transporter in Pseudomonas aeruginosa using fluorescence spectroscopy. Analyst (2014) 0.78
In vitro antibacterial activities of p-toluenesulfonyl-hydrazinothiazoles and hydrazinoselenazoles against multi-drug resistant Gram-negative phenotypes. BMC Pharmacol Toxicol (2016) 0.75
Hfq and its constellation of RNA. Nat Rev Microbiol (2011) 4.94
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures. Nucleic Acids Res (2012) 3.36
Extending CATH: increasing coverage of the protein structure universe and linking structure with function. Nucleic Acids Res (2010) 2.93
Is one solution good enough? Nat Struct Mol Biol (2006) 2.91
Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover. Nature (2005) 2.58
The RNase E of Escherichia coli is a membrane-binding protein. Mol Microbiol (2008) 2.46
A molecular switch and proton wire synchronize the active sites in thiamine enzymes. Science (2004) 2.17
Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46. Structure (2008) 1.98
Running rings around RNA: a superfamily of phosphate-dependent RNases. Trends Biochem Sci (2002) 1.93
Endonucleolytic initiation of mRNA decay in Escherichia coli. Prog Mol Biol Transl Sci (2009) 1.87
Assembly and channel opening in a bacterial drug efflux machine. Mol Cell (2008) 1.74
Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E. J Mol Biol (2004) 1.60
Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions. Nat Methods (2009) 1.51
The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E. Mol Cell (2012) 1.49
A model of a transmembrane drug-efflux pump from Gram-negative bacteria. FEBS Lett (2004) 1.47
Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids Res (2012) 1.40
Structural basis of dynamic glycine receptor clustering by gephyrin. EMBO J (2004) 1.39
The RNA degradosome: life in the fast lane of adaptive molecular evolution. Trends Biochem Sci (2006) 1.38
The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition. Biochemistry (2006) 1.35
Assembly and transport mechanism of tripartite drug efflux systems. Biochim Biophys Acta (2009) 1.31
Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome. J Mol Biol (2008) 1.29
The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 A resolution. J Biol Chem (2005) 1.27
The conformations of polypeptide chains where the main-chain parts of successive residues are enantiomeric. Their occurrence in cation and anion-binding regions of proteins. J Mol Biol (2002) 1.27
Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly. J Mol Biol (2009) 1.26
A processed noncoding RNA regulates an altruistic bacterial antiviral system. Nat Struct Mol Biol (2011) 1.24
Recognition of enolase in the Escherichia coli RNA degradosome. J Mol Biol (2006) 1.22
Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxin-antitoxin partners. Curr Opin Struct Biol (2011) 1.20
Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. DNA Repair (Amst) (2006) 1.18
The crystal structure of the Escherichia coli RNase E apoprotein and a mechanism for RNA degradation. Structure (2008) 1.17
MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. J Biol Chem (2008) 1.16
Conformer generation under restraints. Curr Opin Struct Biol (2006) 1.16
The molecular origins of specificity in the assembly of a multienzyme complex. Structure (2005) 1.14
From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome. Q Rev Biophys (2011) 1.12
Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation. J Mol Biol (2006) 1.09
Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain. Biochemistry (2003) 1.09
Ion mobility mass spectrometry of two tetrameric membrane protein complexes reveals compact structures and differences in stability and packing. J Am Chem Soc (2010) 1.07
Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry. Structure (2010) 1.06
Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly. Open Biol (2012) 1.05
Nanopore-based identification of individual nucleotides for direct RNA sequencing. Nano Lett (2013) 1.04
Recognition and cooperation between the ATP-dependent RNA helicase RhlB and ribonuclease RNase E. J Mol Biol (2006) 1.03
An RNA degradosome assembly in Caulobacter crescentus. Nucleic Acids Res (2010) 1.03
Licensing and due process in the turnover of bacterial RNA. RNA Biol (2013) 1.02
The social fabric of the RNA degradosome. Biochim Biophys Acta (2013) 1.02
The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome. RNA (2010) 1.02
Mimicry by asx- and ST-turns of the four main types of beta-turn in proteins. Protein Sci (2004) 1.02
Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. J Mol Biol (2005) 1.01
Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli. J Biol Chem (2011) 1.00
Recognition of the 70S ribosome and polysome by the RNA degradosome in Escherichia coli. Nucleic Acids Res (2012) 0.97
Model-building strategies for low-resolution X-ray crystallographic data. Acta Crystallogr D Biol Crystallogr (2009) 0.96
"Zn-link": a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E. Biochemistry (2005) 0.96
Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification. J Mol Biol (2005) 0.95
Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Mol Microbiol (2013) 0.95
Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex. J Mol Biol (2007) 0.94
Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics. J Biol Chem (2003) 0.94
Towards genome-scale structure prediction for transmembrane proteins. Philos Trans R Soc Lond B Biol Sci (2006) 0.93
Structural basis for inhibition of homologous recombination by the RecX protein. EMBO J (2008) 0.92
Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3. J Biol Chem (2011) 0.92
Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis. Open Biol (2014) 0.92
Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains. J Biol Chem (2010) 0.92
Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot. Proc Natl Acad Sci U S A (2012) 0.91
Molecular recognition between Escherichia coli enolase and ribonuclease E. Acta Crystallogr D Biol Crystallogr (2010) 0.90
Modulation of heme redox potential in the cytochrome c6 family. J Am Chem Soc (2007) 0.90
Allosteric activation of the ATPase activity of the Escherichia coli RhlB RNA helicase. J Biol Chem (2007) 0.89
Folding and fibril formation of the cell cycle protein Cks1. J Biol Chem (2006) 0.89
Information available at cut rates: structure and mechanism of ribonucleases. Curr Opin Struct Biol (2006) 0.87
Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner. J Biol Chem (2010) 0.86
Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control. RNA Biol (2012) 0.86
Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity. Proc Natl Acad Sci U S A (2010) 0.86
On the antiquity of metalloenzymes and their substrates in bioenergetics. Biochim Biophys Acta (2013) 0.85
A novel main chain motif in proteins bridged by cationic groups: the niche. J Mol Biol (2008) 0.85
Genetic assessment of the role of AcrB β-hairpins in the assembly of the TolC-AcrAB multidrug efflux pump of Escherichia coli. Mol Microbiol (2014) 0.85
A synthetic hexapeptide designed to resemble a proteinaceous P-loop nest is shown to bind inorganic phosphate. Proteins (2012) 0.84
Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. J Mol Biol (2011) 0.84
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis . Biochemistry (2010) 0.84
Control of KirBac3.1 potassium channel gating at the interface between cytoplasmic domains. J Biol Chem (2013) 0.83
Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo. Mol Microbiol (2012) 0.83
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex. Structure (2008) 0.82
Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor. J Mol Graph Model (2007) 0.82
Motivated proteins: a web application for studying small three-dimensional protein motifs. BMC Bioinformatics (2009) 0.82
A potential molecular switch in an alpha-helical coiled coil. Proteins (2008) 0.82
The geometry of alpha-sheet: Implications for its possible function as amyloid precursor in proteins. Proteins (2008) 0.81
Unconventional interactions between water and heterocyclic nitrogens in protein structures. Proteins (2004) 0.81
In silico study of human aquaporin AQP11 and AQP12 channels. Protein Sci (2013) 0.81
The assembly and distribution in vivo of the Escherichia coli RNA degradosome. Biochimie (2013) 0.81
Water and CO₂ permeability of SsAqpZ, the cyanobacterium Synechococcus sp. PCC7942 aquaporin. Biol Cell (2013) 0.80
Neuronal nicotinic acetylcholine receptor agonists: pharmacophores, evolutionary QSAR and 3D-QSAR models. Curr Top Med Chem (2004) 0.79
Off-pathway, oxygen-dependent thiamine radical in the Krebs cycle. J Am Chem Soc (2008) 0.79
Structure of cytochrome c6A, a novel dithio-cytochrome of Arabidopsis thaliana, and its reactivity with plastocyanin: implications for function. J Mol Biol (2006) 0.79
PoreLogo: a new tool to analyse, visualize and compare channels in transmembrane proteins. Bioinformatics (2009) 0.79
Potential regulatory interactions of Escherichia coli RraA protein with DEAD-box helicases. J Biol Chem (2013) 0.78
Mutations at key pore-lining positions differentiate the water permeability of fish lens aquaporin from other vertebrates. FEBS Lett (2010) 0.78
Bridging of anions by hydrogen bonds in nest motifs and its significance for Schellman loops and other larger motifs within proteins. Proteins (2014) 0.78
Simulation of the β- to α-sheet transition results in a twisted sheet for antiparallel and an α-nanotube for parallel strands: implications for amyloid formation. Proteins (2011) 0.78
An ancient anion-binding structural module in RNA and DNA helicases. Proteins (2010) 0.77
The structure of the ends of α-helices in globular proteins: effect of additional hydrogen bonds and implications for helix formation. Proteins (2011) 0.77
Rings and ribbons in protein structures: Characterization using helical parameters and Ramachandran plots for repeating dipeptides. Proteins (2013) 0.77
Purification and characterization of the Caenorhabditis elegans HCF protein and domains of human HCF. Biochemistry (2005) 0.77