Published in Genomics on October 01, 2008
The nonessentiality of essential genes in yeast provides therapeutic insights into a human disease. Genome Res (2016) 1.40
Defining the role of essential genes in human disease. PLoS One (2011) 1.17
Molecular foundations of reproductive lethality in Arabidopsis thaliana. PLoS One (2011) 1.16
Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex. Nat Cell Biol (2010) 1.02
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts. Nucleic Acids Res (2015) 0.88
High-throughput capturing and characterization of mutations in essential genes of Caenorhabditis elegans. BMC Genomics (2014) 0.82
Effects of different kinds of essentiality on sequence evolution of human testis proteins. Sci Rep (2017) 0.75
Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells. Crit Rev Biochem Mol Biol (2015) 0.75
Mixture models for gene expression experiments with two species. Hum Genomics (2014) 0.75
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One (2017) 0.75
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med (2004) 41.02
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet (2009) 7.65
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
Comparative study of the linkage disequilibrium of an ENCODE region, chromosome 7p15, in Korean, Japanese, and Han Chinese samples. Genomics (2006) 2.15
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (2006) 2.08
Longitudinal data analysis in pedigree studies. Genet Epidemiol (2003) 2.06
Th9 cells promote antitumor immune responses in vivo. J Clin Invest (2012) 1.80
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity. Nat Genet (2004) 1.71
The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens. Nat Biotechnol (2004) 1.64
Identification of novel reference genes using multiplatform expression data and their validation for quantitative gene expression analysis. PLoS One (2009) 1.55
Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population. BMC Infect Dis (2006) 1.53
Identification of 15 loci influencing height in a Korean population. J Hum Genet (2009) 1.52
Whole blood manganese correlates with high signal intensities on T1-weighted MRI in patients with liver cirrhosis. Neurotoxicology (2003) 1.52
Joint identification of multiple genetic variants via elastic-net variable selection in a genome-wide association analysis. Ann Hum Genet (2010) 1.51
Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. Hum Mol Genet (2004) 1.46
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (2007) 1.44
Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer. BMC Genomics (2015) 1.44
Risk analysis of aseptic meningitis after measles-mumps-rubella vaccination in Korean children by using a case-crossover design. Am J Epidemiol (2003) 1.43
arrayQCplot: software for checking the quality of microarray data. Bioinformatics (2006) 1.41
Shiftwork and metabolic risk factors of cardiovascular disease. J Occup Health (2005) 1.38
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
The epidemiology of acute pyelonephritis in South Korea, 1997-1999. Am J Epidemiol (2004) 1.29
Elastic-net regularization approaches for genome-wide association studies of rheumatoid arthritis. BMC Proc (2009) 1.26
Diagnostic application of targeted resequencing for familial nonsyndromic hearing loss. PLoS One (2013) 1.24
The validity and reliability of the second korean working conditions survey. Saf Health Work (2013) 1.22
Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population. PLoS One (2010) 1.21
Transglutaminase 2: a multi-functional protein in multiple subcellular compartments. Amino Acids (2010) 1.20
New evaluation measures for multifactor dimensionality reduction classifiers in gene-gene interaction analysis. Bioinformatics (2009) 1.20
Staufen1-mediated mRNA decay functions in adipogenesis. Mol Cell (2012) 1.20
Comparative analyses of DNA methylation and sequence evolution using Nasonia genomes. Mol Biol Evol (2011) 1.20
Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence. Hum Genet (2011) 1.19
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks. BMC Bioinformatics (2007) 1.19
Cancer mortality and incidence in korean semiconductor workers. Saf Health Work (2011) 1.19
Auxin stimulates DWARF4 expression and brassinosteroid biosynthesis in Arabidopsis. Plant J (2011) 1.14
DNA methylation and transcriptional noise. Epigenetics Chromatin (2013) 1.09
A novel method to identify high order gene-gene interactions in genome-wide association studies: gene-based MDR. BMC Bioinformatics (2012) 1.06
Expression breadth and expression abundance behave differently in correlations with evolutionary rates. BMC Evol Biol (2010) 1.03
Identification of differentially expressed subnetworks based on multivariate ANOVA. BMC Bioinformatics (2009) 1.01
The Magnitude of Mortality from Ischemic Heart Disease Attributed to Occupational Factors in Korea - Attributable Fraction Estimation Using Meta-analysis. Saf Health Work (2011) 1.01
Identification of gene-gene interactions in the presence of missing data using the multifactor dimensionality reduction method. Genet Epidemiol (2009) 1.00
Gene-gene interaction analysis for the survival phenotype based on the Cox model. Bioinformatics (2012) 1.00
SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay. Nucleic Acids Res (2012) 0.98
Identification of multiple gene-gene interactions for ordinal phenotypes. BMC Med Genomics (2013) 0.96
What are the determinants of gene expression levels and breadths in the human genome? Hum Mol Genet (2011) 0.96
Multiphasic analysis of whole exome sequencing data identifies a novel mutation of ACTG1 in a nonsyndromic hearing loss family. BMC Genomics (2013) 0.93
Outbreak of sudden cardiac deaths in a tire manufacturing facility: can it be caused by nanoparticles? Saf Health Work (2012) 0.93
Meta-analysis of homogeneous subgroups reveals association between PDE4D gene variants and ischemic stroke. Neuroepidemiology (2011) 0.93
Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture. Exp Mol Med (2012) 0.92
-759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry (2007) 0.92
A modified entropy-based approach for identifying gene-gene interactions in case-control study. PLoS One (2013) 0.92
Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling. BMC Bioinformatics (2007) 0.91
Effect of manganese exposure on MPTP neurotoxicities. Neurotoxicology (2003) 0.90
Age-related distributions of anti-Müllerian hormone level and anti-Müllerian hormone models. Acta Obstet Gynecol Scand (2012) 0.90
Pathway-based evaluation in early onset colorectal cancer suggests focal adhesion and immunosuppression along with epithelial-mesenchymal transition. PLoS One (2012) 0.90
High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: roles of adipocytes and M2-macrophages. Int J Cancer (2014) 0.89
The recognition of occupational diseases attributed to heavy workloads: experiences in Japan, Korea, and Taiwan. Int Arch Occup Environ Health (2011) 0.88
Dye-manufacturing workers and bladder cancer in South Korea. Arch Toxicol (2006) 0.88
Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics-induced obsessive-compulsive symptoms. Arch Gen Psychiatry (2009) 0.88
Robust imputation method for missing values in microarray data. BMC Bioinformatics (2007) 0.87
Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals. BMC Genomics (2014) 0.87
An integrated approach to infer causal associations among gene expression, genotype variation, and disease. Genomics (2009) 0.87
cuGWAM: Genome-wide association multifactor dimensionality reduction using CUDA-enabled high-performance graphics processing unit. Int J Data Min Bioinform (2012) 0.86
Multiple pathway-based genetic variations associated with tobacco related multiple primary neoplasms. PLoS One (2012) 0.86
IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis. BMC Med Genomics (2014) 0.85
DRAK2 participates in a negative feedback loop to control TGF-β/Smads signaling by binding to type I TGF-β receptor. Cell Rep (2012) 0.85
Family history of diabetes and risk of atherosclerotic cardiovascular disease in Korean men and women. Atherosclerosis (2007) 0.85
Genome-wide analysis of haplotype interaction for the data from the North American Rheumatoid Arthritis Consortium. BMC Proc (2009) 0.85
Dropout rate and associated factors in patients with bipolar disorders. J Affect Disord (2012) 0.84
Cognitive profiles of healthy siblings of schizophrenia patients: application of the cognitive domains of the MATRICS consensus battery. World J Biol Psychiatry (2009) 0.84
Multivariate generalized multifactor dimensionality reduction to detect gene-gene interactions. BMC Syst Biol (2013) 0.84
Association tests based on the principal-component analysis. BMC Proc (2007) 0.84
Two-stage normalization using background intensities in cDNA microarray data. BMC Bioinformatics (2004) 0.83
A prognostic model for lymph node-negative breast cancer patients based on the integration of proliferation and immunity. Breast Cancer Res Treat (2011) 0.83
Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against Streptococcus pneumoniae infection. J Infect Dis (2012) 0.83
Lineage-specific variation in slow- and fast-X evolution in primates. Evolution (2012) 0.83
Inference of large-scale gene regulatory networks using regression-based network approach. J Bioinform Comput Biol (2009) 0.83
The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun (2009) 0.83
Network graph analysis of gene-gene interactions in genome-wide association study data. Genomics Inform (2012) 0.82
Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky. Genet Epidemiol (2007) 0.82
Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms. Am J Med Genet B Neuropsychiatr Genet (2011) 0.82
A set of stage-specific gene transcripts identified in EK stage X and HH stage 3 chick embryos. BMC Dev Biol (2007) 0.82
A Bayesian hierarchical model for categorical data with nonignorable nonresponse. Biometrics (2003) 0.82
Response projected clustering for direct association with physiological and clinical response data. BMC Bioinformatics (2008) 0.82
Association analysis of sphingomyelinase 2 polymorphisms for the extrinsic type of atopic dermatitis in Koreans. J Dermatol Sci (2007) 0.82
CDNA array analysis of gene expression profiles in brain of mice exposed to manganese. Ind Health (2004) 0.82
Growth hormone-releasing hormone (GHRH) polymorphisms associated with carcass traits of meat in Korean cattle. BMC Genet (2006) 0.81
An integrative assessment of the psychophysiologic alterations in young women with recurrent major depressive disorder. Psychosom Med (2012) 0.81
Phenotype prediction from genome-wide association studies: application to smoking behaviors. BMC Syst Biol (2012) 0.81
Autophagy-mediated anti-tumoral activity of imiquimod in Caco-2 cells. Biochem Biophys Res Commun (2009) 0.81
Darkness and gulliver2/phyB mutation decrease the abundance of phosphorylated BZR1 to activate brassinosteroid signaling in Arabidopsis. Plant J (2014) 0.81
Evolutionary design principles of modules that control cellular differentiation: consequences for hysteresis and multistationarity. Bioinformatics (2008) 0.81
Practical issues in genome-wide association studies for physical activity. Ann N Y Acad Sci (2011) 0.80
Patterns of cardiorespiratory coordination in young women with recurrent major depressive disorder treated with escitalopram or venlafaxine. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.80