Published in Nucleic Acids Res on September 12, 2008
Surpassing specificity limits of nucleic acid probes via cooperativity. J Mol Diagn (2010) 0.75
Molecular beacons: probes that fluoresce upon hybridization. Nat Biotechnol (1996) 21.49
Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc Natl Acad Sci U S A (1988) 18.72
Production of single-stranded DNA templates by exonuclease digestion following the polymerase chain reaction. Nucleic Acids Res (1989) 4.70
Thermodynamic basis of the enhanced specificity of structured DNA probes. Proc Natl Acad Sci U S A (1999) 4.46
Efficiencies of fluorescence resonance energy transfer and contact-mediated quenching in oligonucleotide probes. Nucleic Acids Res (2002) 2.65
Synthetic multivalent ligands in the exploration of cell-surface interactions. Curr Opin Chem Biol (2000) 2.57
Fluorescein-labeled oligonucleotides for real-time pcr: using the inherent quenching of deoxyguanosine nucleotides. Anal Biochem (2001) 2.23
A novel method to map transcripts: evidence for homology between an adenovirus mRNA and discrete multiple regions of the viral genome. Cell (1977) 1.93
Sandwich hybridization as a convenient method for the detection of nucleic acids in crude samples. Gene (1983) 1.89
Hybridization kinetics and thermodynamics of molecular beacons. Nucleic Acids Res (2003) 1.88
Hitting multiple targets with multimeric ligands. Expert Opin Ther Targets (2004) 1.86
Hybridization of single-stranded DNA targets to immobilized complementary DNA probes: comparison of hairpin versus linear capture probes. Nucleic Acids Res (2001) 1.42
Design and evaluation of oligonucleotide-microarray method for the detection of human intestinal bacteria in fecal samples. FEMS Microbiol Lett (2002) 1.35
A simple method for generating single-stranded DNA probes labeled to high activities. Nucleic Acids Res (1990) 1.32
Targeting drugs to combinations of receptors: a modeling analysis of potential specificity. Ann Biomed Eng (2005) 1.31
Monolithic porous polymer for on-chip solid-phase extraction and preconcentration prepared by photoinitiated in situ polymerization within a microfluidic device. Anal Chem (2001) 1.30
Time-resolved fluorometry: a sensitive method to quantify DNA-hybrids. Nucleic Acids Res (1986) 1.19
Chemiluminescence detection for hybridization assays on the flow-thru chip, a three-dimensional microchannel biochip. Anal Chem (2001) 1.05
Electrochromatography in microchips: reversed-phase separation of peptides and amino acids using photopatterned rigid polymer monoliths. Anal Chem (2002) 1.04
Molecular beacon DNA probes and their bioanalytical applications. Appl Spectrosc (2004) 1.02
Microfluidic chip for high efficiency DNA extraction. Lab Chip (2004) 0.96
Microfluidic purification and preconcentration of mRNA by flow-through polymeric monolith. Anal Chem (2007) 0.90
Characterization of an inexpensive, nontoxic, and highly sensitive microarray substrate. Biotechniques (2004) 0.89
Tentacle Probes: differentiation of difficult single-nucleotide polymorphisms and deletions by presence or absence of a signal in real-time PCR. Clin Chem (2007) 0.87
Tentacle probes: eliminating false positives without sacrificing sensitivity. Nucleic Acids Res (2007) 0.86
Reversed-phase electrochromatography of amino acids and peptides using porous polymer monoliths. J Chromatogr A (2001) 0.85
Conduct-as-cast polymer monoliths as separation media for capillary electrochromatography. Anal Chem (2001) 0.81
DNA probes on beads arrayed in a capillary, 'Bead-array', exhibited high hybridization performance. Nucleic Acids Res (2002) 0.80
A novel sandwich assay with molecular beacon as report probe for nucleic acids detection on one-dimensional microfluidic beads array. Anal Chim Acta (2007) 0.79
Effects of linker length and flexibility on multivalent targeting. Biomacromolecules (2008) 1.02
Heterobivalent ligands target cell-surface receptor combinations in vivo. Proc Natl Acad Sci U S A (2012) 0.94
Two-step synthesis of multivalent cancer-targeting constructs. Biomacromolecules (2010) 0.91
Microfluidic purification and preconcentration of mRNA by flow-through polymeric monolith. Anal Chem (2007) 0.90
Specificity and mobility of biomacromolecular, multivalent constructs for cellular targeting. Biomacromolecules (2007) 0.89
Tentacle Probes: differentiation of difficult single-nucleotide polymorphisms and deletions by presence or absence of a signal in real-time PCR. Clin Chem (2007) 0.87
Tentacle probes: eliminating false positives without sacrificing sensitivity. Nucleic Acids Res (2007) 0.86
Targeted drug delivery for treatment and imaging of glioblastoma multiforme. Expert Opin Drug Deliv (2009) 0.86
Hand-held microanalytical instrument for chip-based electrophoretic separations of proteins. Anal Chem (2005) 0.85
Microchip separations of protein biotoxins using an integrated hand-held device. Electrophoresis (2005) 0.83
Antimicrobial distribution from local delivery depends on dose : a pilot study with MRI. Clin Orthop Relat Res (2014) 0.83
Simplified synthesis and relaxometry of magnetoferritin for magnetic resonance imaging. Magn Reson Med (2010) 0.82
High glucose-mediated loss of cell surface heparan sulfate proteoglycan impairs the endothelial shear stress response. Cytoskeleton (Hoboken) (2010) 0.82
Bioactive surface for neural electrodes: decreasing astrocyte proliferation via transforming growth factor-beta1. J Biomed Mater Res A (2007) 0.81
Optimizing delivery of multivalent targeting constructs for detection of secondary tumors. Ann Biomed Eng (2008) 0.81
Standardized methods to quantify thrombogenicity of blood-contacting materials via thromboelastography. J Biomed Mater Res B Appl Biomater (2011) 0.80
Spatiotemporal quantification of local drug delivery using MRI. Comput Math Methods Med (2013) 0.80
A completely automated sample preparation instrument and consumable device for isolation and purification of nucleic acids. J Lab Autom (2011) 0.80
Jeannette Wilkins Award: Can locally delivered gadolinium be visualized on MRI? A pilot study. Clin Orthop Relat Res (2012) 0.80
Pyridoxine restores endothelial cell function in high glucose. Metab Syndr Relat Disord (2010) 0.77
An ultra-high temperature flow-through capillary device for bacterial spore lysis. Electrophoresis (2010) 0.77
Temporal differences in Erk1/2 activity distinguish among combinations of extracellular matrix components. Acta Biomater (2011) 0.76
Temporal and spatial control of neural effects following intracerebral microinfusion. J Drug Target (2008) 0.76
Distribution of molecules locally delivered from bone cement. J Biomed Mater Res B Appl Biomater (2013) 0.75
Surpassing specificity limits of nucleic acid probes via cooperativity. J Mol Diagn (2010) 0.75
Glioblastoma targeting via integrins is concentration dependent. Biotechnol Bioeng (2009) 0.75
Intracellular signaling controls endothelial cell prostacyclin secretion and regulation of blood clotting time. J Biomed Mater Res A (2012) 0.75
Michael-type addition reactions in NIPAAm-cysteamine copolymers follow second order rate laws with steric hindrance. Ann Biomed Eng (2009) 0.75