Published in Chem Rev on September 19, 2008
Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation. Acta Biomater (2010) 1.00
Chondrogenic ATDC5 cells: an optimised model for rapid and physiological matrix mineralisation. Int J Mol Med (2012) 0.95
Calcium orthophosphates: occurrence, properties, biomineralization, pathological calcification and biomimetic applications. Biomatter (2013) 0.94
Accelerated osteoblast mineralization on a conductive substrate by multiple electrical stimulation. J Bone Miner Metab (2011) 0.90
Developmental-like bone regeneration by human embryonic stem cell-derived mesenchymal cells. Tissue Eng Part A (2013) 0.89
Osteoinduction and proliferation of bone-marrow stromal cells in three-dimensional poly (ε-caprolactone)/ hydroxyapatite/collagen scaffolds. J Transl Med (2015) 0.83
The Phosphate Source Influences Gene Expression and Quality of Mineralization during In Vitro Osteogenic Differentiation of Human Mesenchymal Stem Cells. PLoS One (2013) 0.81
Collagen osteoid-like model allows kinetic gene expression studies of non-collagenous proteins in relation with mineral development to understand bone biomineralization. PLoS One (2013) 0.81
Design and characterization of calcium phosphate ceramic scaffolds for bone tissue engineering. Dent Mater (2015) 0.80
Endochondral ossification for enhancing bone regeneration: converging native extracellular matrix biomaterials and developmental engineering in vivo. Tissue Eng Part B Rev (2014) 0.78
Calcium orthophosphates (CaPO4): occurrence and properties. Prog Biomater (2015) 0.78
Rediscovering Hydrogel-Based Double-Diffusion Systems for Studying Biomineralization. CrystEngComm (2012) 0.77
Biomineralization Guided by Paper Templates. Sci Rep (2016) 0.77
Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films. Int J Nanomedicine (2015) 0.76
Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification. J Vis Exp (2016) 0.75
Secretory pathway Ca(2+) -ATPases promote in vitro microcalcifications in breast cancer cells. Mol Carcinog (2017) 0.75
Tissue engineering. Science (1993) 19.65
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell (2002) 15.20
Mesenchymal stem cells as trophic mediators. J Cell Biochem (2006) 9.38
Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell (1982) 6.61
In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol (1983) 5.39
Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J Bone Miner Res (1999) 4.68
Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res (1973) 4.54
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. J Exp Med (2004) 3.88
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation. FASEB J (2005) 3.61
Osteoclasts: what do they do and how do they do it? Am J Pathol (2007) 2.93
Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation. Proc Natl Acad Sci U S A (2005) 2.88
Endochondral ossification: how cartilage is converted into bone in the developing skeleton. Int J Biochem Cell Biol (2007) 2.81
Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res (1988) 2.74
Role of macromolecular assembly of enamel matrix proteins in enamel formation. J Dent Res (2006) 2.69
Establishment of an osteocyte-like cell line, MLO-Y4. J Bone Miner Res (1997) 2.55
Sea urchin spine calcite forms via a transient amorphous calcium carbonate phase. Science (2004) 2.45
The effect of recombinant mouse amelogenins on the formation and organization of hydroxyapatite crystals in vitro. J Struct Biol (2005) 2.43
Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene. Bone (2004) 2.35
Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo. J Cell Biol (2003) 2.31
FT-IR imaging of native and tissue-engineered bone and cartilage. Biomaterials (2006) 2.27
Application of vibrational spectroscopy to the study of mineralized tissues (review). J Biomed Opt (2000) 2.21
Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. J Orthop Res (2002) 2.18
Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res (1999) 2.11
Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation. J Orthop Res (1997) 2.11
Growth of embryonic avian and mammalian tibiae on a relatively simple chemically defined medium. Exp Cell Res (1961) 2.11
Dentin matrix protein 1 is predominantly expressed in chicken and rat osteocytes but not in osteoblasts. J Bone Miner Res (2001) 2.06
Cultivation in vitro of cells derived from a human osteosarcoma. Cancer (1971) 2.06
Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties. Cancer Res (1987) 2.03
Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity. J Biol Chem (2007) 2.03
A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ Dev (1990) 2.00
Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells. J Bone Miner Res (1992) 1.98
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol Cell Biol (2006) 1.98
Development and characterization of a conditionally immortalized human fetal osteoblastic cell line. J Bone Miner Res (1995) 1.97
The serum protein alpha2-HS glycoprotein/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells. A possible role in mineralization and calcium homeostasis. J Biol Chem (1996) 1.94
von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Calcif Tissue Int (2003) 1.92
Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin Orthop Relat Res (1980) 1.91
The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem Biophys Res Commun (1990) 1.88
Stage-related capacity for limb chondrogenesis in cell culture. Dev Biol (1977) 1.87
Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP). J Biol Chem (1995) 1.86
Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1. Proc Natl Acad Sci U S A (2001) 1.85
Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells. Am J Physiol Cell Physiol (2005) 1.76
HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway. Autophagy (2007) 1.73
Dentinogenesis. Crit Rev Oral Biol Med (1993) 1.72
Self-assembly of a recombinant amelogenin protein generates supramolecular structures. J Struct Biol (1994) 1.71
In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells (2003) 1.67
In vitro differentiation of embryonic stem cells into mineralized osteoblasts. Differentiation (2003) 1.65
Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? J Dent Res (2005) 1.65
Establishment of an osteoid preosteocyte-like cell MLO-A5 that spontaneously mineralizes in culture. J Bone Miner Res (2001) 1.64
Amelotin--a Novel Secreted, Ameloblast-specific Protein. J Dent Res (2005) 1.59
In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation. J Bone Miner Res (2003) 1.57
Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J Biol Chem (2005) 1.57
The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex. J Biol Chem (2003) 1.56
Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures. Calcif Tissue Int (2002) 1.53
Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures. Differentiation (1999) 1.52
Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes. J Biol Chem (2000) 1.52
Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells. J Cell Physiol (1990) 1.50
Amelogenin-guided crystal growth on fluoroapatite glass-ceramics. J Dent Res (2004) 1.49
Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling. J Cell Biochem (2002) 1.49
Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate. Bone Miner (1991) 1.48
Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro. J Bone Miner Res (1997) 1.46
3. Protein-protein interactions of the developing enamel matrix. Curr Top Dev Biol (2006) 1.46
Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro. Bone (2007) 1.45
Mechanism by which MLO-A5 late osteoblasts/early osteocytes mineralize in culture: similarities with mineralization of lamellar bone. Calcif Tissue Int (2006) 1.44
Examination of mineralized nodule formation in living osteoblastic cultures using fluorescent dyes. Biotechnol Prog (2006) 1.43
Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification. J Biol Chem (2006) 1.41
Mineralization of developing mouse calvaria as revealed by Raman microspectroscopy. J Bone Miner Res (2002) 1.41
Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells. Proc Natl Acad Sci U S A (2003) 1.40
Self-assembly of synthetic hydroxyapatite nanorods into an enamel prism-like structure. J Colloid Interface Sci (2005) 1.38
Dentin matrix protein 4, a novel secretory calcium-binding protein that modulates odontoblast differentiation. J Biol Chem (2007) 1.38
Comparison of the action of transient and continuous PTH on primary osteoblast cultures expressing differentiation stage-specific GFP. J Bone Miner Res (2004) 1.36
Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice. J Bone Miner Res (2000) 1.35
Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes. J Bone Miner Metab (2007) 1.34
Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice. Endocrinology (1996) 1.32
Antisense inhibition of AMEL translation demonstrates supramolecular controls for enamel HAP crystal growth during embryonic mouse molar development. Development (1993) 1.30
In vivo bone formation by human bone marrow stromal cells: reconstruction of the mouse calvarium and mandible. Stem Cells (2006) 1.29
Expression of mineralization markers in dental pulp cells. J Endod (2007) 1.29
New insights into extracellular matrix assembly and reorganization from dynamic imaging of extracellular matrix proteins in living osteoblasts. J Cell Sci (2006) 1.28
Gap-junctional communication is required for the maturation process of osteoblastic cells in culture. Bone (2001) 1.28
Osteocyte shape is dependent on actin filaments and osteocyte processes are unique actin-rich projections. J Bone Miner Res (1998) 1.28
Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Adv Dent Res (1999) 1.28
Expression of bone-specific genes by hypertrophic chondrocytes: implication of the complex functions of the hypertrophic chondrocyte during endochondral bone development. J Cell Biochem (1996) 1.26
Encapsulation of adult human mesenchymal stem cells within collagen-agarose microenvironments. Biotechnol Bioeng (2005) 1.25
Hypertrophic chondrocytes undergo further differentiation in culture. J Cell Biol (1992) 1.25
The derivation of mesenchymal stem cells from human embryonic stem cells. Cells Tissues Organs (2008) 1.24
Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organ. Arch Oral Biol (1992) 1.24
Isolation, proliferation and differentiation of osteoblastic cells to study cell/biomaterial interactions: comparison of different isolation techniques and source. Biomaterials (2004) 1.24
Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes. Osteoarthritis Cartilage (2005) 1.23
Substrate dependent differences in morphology and elasticity of living osteoblasts investigated by atomic force microscopy. Colloids Surf B Biointerfaces (2000) 1.23
Transient precursor strategy in mineral formation of bone. Bone (2006) 1.23
Acidosis inhibits bone formation by osteoblasts in vitro by preventing mineralization. Calcif Tissue Int (2005) 1.22
Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells. Biomaterials (2006) 1.22
Wnt10a regulates dentin sialophosphoprotein mRNA expression and possibly links odontoblast differentiation and tooth morphogenesis. Differentiation (2007) 1.22
Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. J Bone Miner Res (2002) 1.21
Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb. J Cell Biol (1999) 1.18
Establishment and characterization of an osteocyte-like cell line, MLO-Y4. J Bone Miner Metab (1999) 1.17
Bone acidic glycoprotein-75 delineates the extracellular sites of future bone sialoprotein accumulation and apatite nucleation in osteoblastic cultures. J Biol Chem (2004) 1.17
Temperature sensitive simian virus 40 large T antigen immortalization of murine odontoblast cell cultures: establishment of clonal odontoblast cell line. Connect Tissue Res (1995) 1.16
MEPE is downregulated as dental pulp stem cells differentiate. Arch Oral Biol (2005) 1.16
Calcification as an indicator of osteoinductive capacity of biomaterials in osteoblastic cell cultures. Biomaterials (2005) 1.15
Fetal bovine serum: a multivariate standard. Proc Soc Exp Biol Med (1975) 1.15
Modulation of extracellular matrix protein phosphorylation alters mineralization in differentiating chick limb-bud mesenchymal cell micromass cultures. Bone (2008) 0.89
Changes in matrix protein gene expression associated with mineralization in the differentiating chick limb-bud micromass culture system. J Cell Biochem (2011) 0.78