Published in J Biol Chem on February 22, 2005
Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One (2008) 2.96
Identification of differentially expressed genes between osteoblasts and osteocytes. Bone (2009) 1.97
Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. Bone (2011) 1.96
The osteocyte: an endocrine cell ... and more. Endocr Rev (2013) 1.84
Osteocyte apoptosis. Bone (2012) 1.73
Mechanosensation and Transduction in Osteocytes. Bonekey Osteovision (2006) 1.50
Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol (2011) 1.50
Osteocyte RANKL: new insights into the control of bone remodeling. J Bone Miner Res (2012) 1.29
Isolation and culture of primary osteocytes from the long bones of skeletally mature and aged mice. Biotechniques (2012) 1.26
Central role of pyrophosphate in acellular cementum formation. PLoS One (2012) 1.14
Periodontal breakdown in the Dmp1 null mouse model of hypophosphatemic rickets. J Dent Res (2008) 1.14
The progressive ankylosis protein regulates cementum apposition and extracellular matrix composition. Cells Tissues Organs (2011) 1.11
Genetic mouse models for bone studies--strengths and limitations. Bone (2011) 1.10
In vitro and in vivo approaches to study osteocyte biology. Bone (2012) 1.09
Loss of dentin sialophosphoprotein leads to periodontal diseases in mice. J Periodontal Res (2012) 1.05
Osteocyte signaling in bone. Curr Osteoporos Rep (2012) 1.04
Expression and function of Dlx genes in the osteoblast lineage. Dev Biol (2008) 1.04
Gene expression signatures of a fibroblastoid preosteoblast and cuboidal osteoblast cell model compared to the MLO-Y4 osteocyte cell model. Bone (2008) 0.99
DMP1 and MEPE expression are elevated in osteocytes after mechanical loading in vivo: theoretical role in controlling mineral quality in the perilacunar matrix. J Musculoskelet Neuronal Interact (2007) 0.99
Time lapse imaging techniques for comparison of mineralization dynamics in primary murine osteoblasts and the late osteoblast/early osteocyte-like cell line MLO-A5. Cells Tissues Organs (2008) 0.98
Cell culture systems for studies of bone and tooth mineralization. Chem Rev (2008) 0.94
Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity. J Cell Biochem (2009) 0.94
Immunolocalization of sibling and RUNX2 proteins during vertical distraction osteogenesis in the human mandible. J Histochem Cytochem (2007) 0.93
Connexin 43 channels are essential for normal bone structure and osteocyte viability. J Bone Miner Res (2015) 0.91
Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption-formation cycles? Osteoporos Int (2014) 0.90
Identification of secretory odontoblasts using DMP1-GFP transgenic mice. Bone (2010) 0.87
Load/strain distribution between ulna and radius in the mouse forearm compression loading model. Med Eng Phys (2011) 0.86
Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam). Eur J Oral Sci (2008) 0.85
Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts. PLoS One (2013) 0.85
Bone's responses to mechanical loading are impaired in type 1 diabetes. Bone (2015) 0.83
Do osteocytes contribute to phosphate homeostasis? Curr Opin Nephrol Hypertens (2009) 0.82
Novel approaches for two and three dimensional multiplexed imaging of osteocytes. Bone (2015) 0.79
Characterization of Fam20C expression in odontogenesis and osteogenesis using transgenic mice. Int J Oral Sci (2015) 0.79
Identifying promoter elements necessary for enamelin tissue-specific expression. Cells Tissues Organs (2008) 0.78
Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia. J Bone Miner Res (2016) 0.78
The Role of the Osteocyte in Bone and Nonbone Disease. Endocrinol Metab Clin North Am (2016) 0.78
Histological evidence that metformin reverses the adverse effects of diabetes on orthodontic tooth movement in rats. J Mol Histol (2016) 0.77
Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis. Oncogene (2016) 0.77
Visual reporters for study of the osteoblast lineage. Bone (2016) 0.75
Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes. Cell Biochem Funct (2017) 0.75
Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet (2006) 7.53
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature (2008) 6.61
CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res (2006) 6.35
Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med (2011) 5.66
Lrp5 functions in bone to regulate bone mass. Nat Med (2011) 5.33
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem (2005) 5.33
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem (2007) 4.74
Bone loss and bone size after menopause. N Engl J Med (2003) 4.64
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood (2004) 4.56
Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab (2006) 3.57
Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng (2006) 3.46
Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21
The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem (2006) 3.04
Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One (2008) 2.96
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol (2005) 2.94
Genetics of osteoporosis. Endocr Rev (2002) 2.91
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol (2010) 2.85
Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Mol Biol Cell (2005) 2.75
Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70
Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation. J Bone Miner Res (2012) 2.53
DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J Bone Miner Res (2005) 2.46
Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice. J Bone Miner Res (2005) 2.41
Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res (2002) 2.36
Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2. J Bone Miner Res (2013) 2.25
Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A (2011) 2.24
Bioactive glass in tissue engineering. Acta Biomater (2011) 2.23
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Proc Natl Acad Sci U S A (2010) 2.20
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genet (2012) 2.19
Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway. PLoS One (2011) 2.10
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet (2005) 2.10
Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest (2012) 2.10
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells (2006) 2.09
Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts. J Bone Miner Res (2002) 2.08
Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology (2004) 2.02
Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Dev Biol (2006) 2.00
Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts. J Bone Miner Res (2007) 1.99
Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix. J Biol Chem (2002) 1.99
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol Cell Biol (2006) 1.98
Identification of differentially expressed genes between osteoblasts and osteocytes. Bone (2009) 1.97
Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. Bone (2011) 1.96
Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome. Sci Transl Med (2013) 1.90
Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation. J Cell Biol (2002) 1.88
Histological analysis of GFP expression in murine bone. J Histochem Cytochem (2005) 1.87
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
The osteocyte: an endocrine cell ... and more. Endocr Rev (2013) 1.84
Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem (2005) 1.83
Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood (2012) 1.83
The effects of dynamic axial loading on the rat growth plate. J Bone Miner Res (2002) 1.82
The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem (2005) 1.81
Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo. J Biol Chem (2003) 1.81
Designing exercise regimens to increase bone strength. Exerc Sport Sci Rev (2003) 1.80
Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J (2011) 1.74
Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression. J Biol Chem (2006) 1.68
Mechanical loading stimulates dentin matrix protein 1 (DMP1) expression in osteocytes in vivo. J Bone Miner Res (2003) 1.66
Analysis of αSMA-labeled progenitor cell commitment identifies notch signaling as an important pathway in fracture healing. J Bone Miner Res (2014) 1.66
Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms. Am J Physiol Cell Physiol (2009) 1.64
Local communication on and within bone controls bone remodeling. Bone (2009) 1.59
Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Bone (2008) 1.59
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem (2007) 1.55
Pathogenic role of Fgf23 in Dmp1-null mice. Am J Physiol Endocrinol Metab (2008) 1.55
Effects of raloxifene on bone density, biomarkers, and histomorphometric and biomechanical measures in ovariectomized cynomolgus monkeys. Menopause (2002) 1.55
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54
Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading. J Biol Chem (2008) 1.52
Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age. J Bone Miner Res (2014) 1.52
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52
Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol (2011) 1.50
Osteocyte lacunae tissue strain in cortical bone. J Biomech (2005) 1.49
Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways. J Bone Miner Res (2010) 1.47
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Mol Cell Biol (2006) 1.45
A model for mechanotransduction in bone cells: the load-bearing mechanosomes. J Cell Biochem (2003) 1.45
In vivo fate mapping identifies mesenchymal progenitor cells. Stem Cells (2012) 1.44