Zhongcong Xie

Author PubWeight™ 55.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology 2011 2.41
2 2-deoxy-D-glucose enhances anesthetic effects in mice. Anesth Analg 2015 1.99
3 Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology 2013 1.93
4 The effects of isoflurane and desflurane on cognitive function in humans. Anesth Analg 2011 1.88
5 Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol 2012 1.76
6 Perioperative cognitive decline in the aging population. Mayo Clin Proc 2011 1.66
7 The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem 2009 1.64
8 The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β. Neurobiol Aging 2010 1.62
9 The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol 2009 1.56
10 Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease. Anesth Analg 2009 1.55
11 Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci 2008 1.44
12 Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology 2010 1.38
13 Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res 2009 1.37
14 The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem 2008 1.31
15 Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion. J Biol Chem 2006 1.26
16 Career National Institutes of Health funding and scholarship of chairpersons of academic departments of anesthesiology and surgery. Anesthesiology 2007 1.18
17 Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels. Anesthesiology 2009 1.17
18 Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice. Anesthesiology 2013 1.16
19 Brief review: anesthetic neurotoxicity in the elderly, cognitive dysfunction and Alzheimer's disease. Can J Anaesth 2010 1.10
20 Isoflurane decreases self-renewal capacity of rat cultured neural stem cells. Anesthesiology 2011 1.06
21 Academic productivity of directors of ACGME-accredited residency programs in surgery and anesthesiology. Anesth Analg 2014 1.06
22 Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in mice. J Neurosci 2013 1.01
23 The potential dual effects of anesthetic isoflurane on Aβ-induced apoptosis. Curr Alzheimer Res 2011 0.98
24 Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization. PLoS One 2011 0.98
25 Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice. Anesthesiology 2014 0.97
26 Sleep disturbance induces neuroinflammation and impairment of learning and memory. Neurobiol Dis 2012 0.96
27 Spatial memory is intact in aged rats after propofol anesthesia. Anesth Analg 2008 0.95
28 Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation. PLoS One 2012 0.95
29 The potential dual effects of anesthetic isoflurane on hypoxia-induced caspase-3 activation and increases in β-site amyloid precursor protein-cleaving enzyme levels. Anesth Analg 2011 0.94
30 General anesthetic-induced neurotoxicity: an emerging problem for the young and old? Curr Opin Anaesthesiol 2007 0.93
31 Altered hippocampal gene expression 2 days after general anesthesia in rats. Eur J Pharmacol 2006 0.92
32 Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet 2007 0.89
33 Epigenetic enhancement of brain-derived neurotrophic factor signaling pathway improves cognitive impairments induced by isoflurane exposure in aged rats. Mol Neurobiol 2014 0.88
34 Neurotoxicity of general anesthetics: an update. Curr Pharm Des 2012 0.88
35 2-Deoxy-D-glucose attenuates isoflurane-induced cytotoxicity in an in vitro cell culture model of H4 human neuroglioma cells. Anesth Analg 2011 0.86
36 Propofol and magnesium attenuate isoflurane-induced caspase-3 activation via inhibiting mitochondrial permeability transition pore. Med Gas Res 2012 0.82
37 Sevoflurane induces tau phosphorylation and glycogen synthase kinase 3β activation in young mice. Anesthesiology 2014 0.82
38 RNA interference-mediated silencing of BACE and APP attenuates the isoflurane-induced caspase activation. Med Gas Res 2011 0.81
39 Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats. Neurol Res 2012 0.81
40 Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochem Res 2012 0.81
41 Anesthetic sevoflurane reduces levels of hippocalcin and postsynaptic density protein 95. Mol Neurobiol 2014 0.79
42 Effects of anesthetic isoflurane and desflurane on human cerebrospinal fluid Aβ and τ level. Anesthesiology 2013 0.79
43 Inflammatory pain may induce cognitive impairment through an interlukin-6-dependent and postsynaptic density-95-associated mechanism. Anesth Analg 2014 0.79
44 Glucose may attenuate isoflurane-induced caspase-3 activation in H4 human neuroglioma cells. Anesth Analg 2014 0.79
45 Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density. J Alzheimers Dis 2010 0.78
46 Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study. Plast Reconstr Surg 2005 0.78
47 Preoperative Cognitive Stratification of Older Elective Surgical Patients: A Cross-Sectional Study. Anesth Analg 2016 0.78
48 Neuronal vulnerability to anesthesia neurotoxicity depends on age of neurons. Ann Neurol 2013 0.77
49 Propofol Enhances Hemoglobin-Induced Cytotoxicity in Neurons. Anesth Analg 2016 0.77
50 Cancer prognosis: can anesthesia play a role? Anesthesiology 2013 0.75
51 Sevoflurane Acts on Ubiquitination-Proteasome Pathway to Reduce Postsynaptic Density 95 Protein Levels in Young Mice. Anesthesiology 2017 0.75
52 Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol 2012 0.75
53 Correction to Direct Tracking of Amyloid and Tau Dynamics in Neuroblastoma Cells Using Nanoplasmonic Fiber Tip Probes. Nano Lett 2016 0.75
54 Artefactual effects of lipid-based cell transfection reagents on AbetaPP processing and Abeta production. Amyloid 2006 0.75
55 Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice. Anesthesiology 2020 0.75
56 Differential changes of alveolar gas concentrations during anesthetic induction of a patient with an absent right pulmonary artery. Anesth Analg 2006 0.75