Published in Anesth Analg on October 01, 2008
Risk of dementia after anaesthesia and surgery. Br J Psychiatry (2013) 3.46
Perioperative cognitive decline in the aging population. Mayo Clin Proc (2011) 1.66
Neurotoxicity of general anesthetics: cause for concern? Anesthesiology (2009) 1.13
Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization. PLoS One (2011) 0.98
A retrospective cohort-matched comparison of conscious sedation versus general anesthesia for supratentorial glioma resection. Clinical article. J Neurosurg (2010) 0.96
Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats. J Anesth (2011) 0.89
Lasting impact of general anaesthesia on the brain: mechanisms and relevance. Nat Rev Neurosci (2016) 0.83
Propofol prevents electroconvulsive-shock-induced memory impairment through regulation of hippocampal synaptic plasticity in a rat model of depression. Neuropsychiatr Dis Treat (2014) 0.77
Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro. PLoS One (2016) 0.77
Intranasal Insulin Prevents Anesthesia-Induced Cognitive Impairment and Chronic Neurobehavioral Changes. Front Aging Neurosci (2017) 0.75
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet (2007) 12.13
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Sci Transl Med (2012) 6.27
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci U S A (2003) 5.44
The genetics of Alzheimer disease: back to the future. Neuron (2010) 4.91
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat Rev Neurosci (2008) 4.64
Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med (2005) 4.34
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron (2009) 4.12
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron (2007) 3.98
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol (2003) 3.58
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta. Neuron (2013) 3.43
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol (2004) 3.24
Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet (2003) 3.00
Alzheimer's disease: the cholesterol connection. Nat Neurosci (2003) 2.99
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide. PLoS One (2010) 2.78
The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat Rev Neurosci (2012) 2.76
Frontal cortex subregions play distinct roles in choices between actions and stimuli. J Neurosci (2008) 2.71
The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg (2003) 2.69
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (2011) 2.66
The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol (2008) 2.54
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell (2010) 2.46
Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats. Anesthesiology (2004) 2.45
The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation. J Neurosci (2007) 2.42
Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology (2011) 2.41
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron (2008) 2.30
Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. J Neurosci (2011) 2.29
The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology (2006) 2.26
Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease. Neuron (2010) 2.20
Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats. Learn Mem (2002) 2.13
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
The genetic epidemiology of neurodegenerative disease. J Clin Invest (2005) 2.08
An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. J Biol Chem (2002) 2.00
2-deoxy-D-glucose enhances anesthetic effects in mice. Anesth Analg (2015) 1.99
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). J Biol Chem (2002) 1.99
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology (2013) 1.93
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet (2003) 1.91
General anesthesia--minding the mind during surgery. N Engl J Med (2011) 1.89
The effects of isoflurane and desflurane on cognitive function in humans. Anesth Analg (2011) 1.88
Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci (2006) 1.83
Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol (2012) 1.76
Genome-wide association studies in Alzheimer's disease. Hum Mol Genet (2009) 1.70
The synaptic Abeta hypothesis of Alzheimer disease. Nat Neurosci (2005) 1.68
Perioperative cognitive decline in the aging population. Mayo Clin Proc (2011) 1.66
The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem (2009) 1.64
The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β. Neurobiol Aging (2010) 1.62
Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol (2008) 1.60
Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg (2004) 1.60
Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. J Neurosci (2010) 1.58
Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics (2008) 1.58
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. J Alzheimers Dis (2010) 1.57
The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol (2009) 1.56
Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease. Anesth Analg (2009) 1.55
The current status of Alzheimer's disease genetics: what do we tell the patients? Pharmacol Res (2004) 1.53
BACE is degraded via the lysosomal pathway. J Biol Chem (2005) 1.53
A 20-year longitudinal study of body weight, dieting, and eating disorder symptoms. J Abnorm Psychol (2007) 1.51
Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity. Anesthesiology (2015) 1.48
Alzheimer's disease: one disorder, too many genes? Hum Mol Genet (2004) 1.48
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum Mol Genet (2009) 1.46
Serum biomarkers for delirium. J Gerontol A Biol Sci Med Sci (2006) 1.45
Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (2013) 1.45
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation. J Neurosci (2005) 1.41
Alzheimer's disease and post-operative cognitive dysfunction. Exp Gerontol (2006) 1.41
Application of a latent class analysis to empirically define eating disorder phenotypes. Arch Gen Psychiatry (2004) 1.39
Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology (2010) 1.38
Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res (2009) 1.37