Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMC 2707263)

Published in Exerc Sport Sci Rev on October 01, 2008

Authors

Deborah J Good1, Christopher A Coyle, Dana L Fox

Author Affiliations

1: Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA, USA. goodd@vt.edu

Articles citing this

The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives. J Exp Biol (2011) 2.34

SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive. Cell (2011) 1.86

Genetic variation in the pleiotropic association between physical activity and body weight in mice. Genet Sel Evol (2009) 1.05

Heritability of objectively assessed daily physical activity and sedentary behavior. Am J Clin Nutr (2013) 1.02

Current understanding of the genetic basis for physical activity. J Nutr (2011) 0.99

Genetic determinants of voluntary exercise. Trends Genet (2013) 0.90

Genetic variation for body weight change in mice in response to physical exercise. BMC Genet (2009) 0.90

Deletion of Nhlh2 results in a defective torpor response and reduced Beta adrenergic receptor expression in adipose tissue. PLoS One (2010) 0.80

Driven to be inactive? The genetics of physical activity. Prog Mol Biol Transl Sci (2010) 0.79

Leptin signaling regulates hypothalamic expression of nescient helix-loop-helix 2 (Nhlh2) through signal transducer and activator 3 (Stat3). Mol Cell Endocrinol (2014) 0.77

Comparison of gene and protein expressions in rats residing in standard cages with those having access to an exercise wheel. Biomed Res Int (2014) 0.77

Differential gene expression in high- and low-active inbred mice. Biomed Res Int (2014) 0.76

NHLH2: at the intersection of obesity and fertility. Trends Endocrinol Metab (2013) 0.76

Articles cited by this

The human obesity gene map: the 2005 update. Obesity (Silver Spring) (2006) 7.17

Genetics of obesity in humans. Endocr Rev (2006) 5.42

Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies. J Am Coll Cardiol (2006) 2.73

Autosomal recessive catecholamine- or exercise-induced polymorphic ventricular tachycardia: clinical features and assignment of the disease gene to chromosome 1p13-21. Circulation (2001) 1.56

A two-base deletion -439delGC in the melanocortin-4 receptor promoter associated with early-onset obesity. Horm Res (2006) 1.52

A quantitative trait locus on chromosome 18q for physical activity and dietary intake in Hispanic children. Obesity (Silver Spring) (2006) 1.44

The human gene map for performance and health-related fitness phenotypes: the 2005 update. Med Sci Sports Exerc (2006) 1.42

Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet (1997) 1.41

The critical role of the melanocortin system in the control of energy balance. Annu Rev Nutr (2004) 1.19

Reduced voluntary activity precedes adult-onset obesity in Nhlh2 knockout mice. Physiol Behav (2002) 1.15

Melanocortin-4 receptor gene and physical activity in the Québec Family Study. Int J Obes (Lond) (2005) 1.15

The central melanocortin system and the regulation of energy balance. Front Biosci (2007) 1.11

hnRNP-U enhances the expression of specific genes by stabilizing mRNA. FEBS Lett (2006) 1.04

Contribution of different mechanisms to compensation for energy restriction in the mouse. Obes Res (2005) 1.00

Energy balance pathways converging on the Nhlh2 transcription factor. Front Biosci (2007) 0.89