Published in Trends Genet on January 23, 2013
Wheel running in the wild. Proc Biol Sci (2014) 1.08
Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int (2015) 0.78
Quantitative genomics of voluntary exercise in mice: transcriptional analysis and mapping of expression QTL in muscle. Physiol Genomics (2014) 0.77
Maternal exercise before and during pregnancy does not impact offspring exercise or body composition in mice. J Negat Results Biomed (2015) 0.77
Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity. J Dev Orig Health Dis (2015) 0.77
Long-term exercise in mice has sex-dependent benefits on body composition and metabolism during aging. Physiol Rep (2016) 0.75
Maternal exercise during pregnancy promotes physical activity in adult offspring. FASEB J (2016) 0.75
Childhood temperament predictors of adolescent physical activity. BMC Public Health (2017) 0.75
Running from Disease: Molecular Mechanisms Associating Dopamine and Leptin Signaling in the Brain with Physical Inactivity, Obesity, and Type 2 Diabetes. Front Endocrinol (Lausanne) (2017) 0.75
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature (2012) 14.67
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Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol (2012) 4.87
Evidence for prescribing exercise as therapy in chronic disease. Scand J Med Sci Sports (2006) 4.80
Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science (2005) 4.76
Endurance running and the evolution of Homo. Nature (2004) 4.10
The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics (2012) 3.84
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Physical activity levels among children aged 9-13 years--United States, 2002. MMWR Morb Mortal Wkly Rep (2003) 3.04
How many steps/day are enough? For adults. Int J Behav Nutr Phys Act (2011) 2.92
Time use and physical activity: a shift away from movement across the globe. Obes Rev (2012) 2.83
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Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab (2012) 2.46
The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives. J Exp Biol (2011) 2.34
The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc (2009) 2.30
Physical activity energy expenditure has not declined since the 1980s and matches energy expenditures of wild mammals. Int J Obes (Lond) (2008) 2.17
Changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women. PLoS One (2009) 2.08
A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. J Appl Physiol (1985) (2010) 2.07
Muscles and their myokines. J Exp Biol (2011) 2.07
Artificial selection for increased wheel-running behavior in house mice. Behav Genet (1998) 2.03
Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol (1985) (2010) 1.88
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J Biol Chem (2007) 1.85
Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One (2012) 1.84
The use of a running wheel to measure activity in rodents: relationship to energy balance, general activity, and reward. Neurosci Biobehav Rev (2012) 1.45
Quantitative trait loci for physical activity traits in mice. Physiol Genomics (2008) 1.45
A quantitative trait locus on chromosome 18q for physical activity and dietary intake in Hispanic children. Obesity (Silver Spring) (2006) 1.44
Genetic analysis of physical activity in twins. Am J Clin Nutr (2005) 1.40
A strategy for the integration of QTL, gene expression, and sequence analyses. Mamm Genome (2003) 1.38
Epigenetics and lifestyle. Epigenomics (2011) 1.34
Physical activity and global genomic DNA methylation in a cancer-free population. Epigenetics (2011) 1.32
Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics (2010) 1.30
Minireview: Epigenetics of obesity and diabetes in humans. Endocrinology (2012) 1.25
Phenotypic plasticity and experimental evolution. J Exp Biol (2006) 1.24
Do big-brained animals play more? Comparative analyses of play and relative brain size in mammals. J Comp Psychol (2001) 1.23
Genome-wide association study of exercise behavior in Dutch and American adults. Med Sci Sports Exerc (2009) 1.22
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
An epistatic genetic basis for physical activity traits in mice. J Hered (2008) 1.19
Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study. Diabetologia (2012) 1.17
Aerobic exercise is the critical variable in an enriched environment that increases hippocampal neurogenesis and water maze learning in male C57BL/6J mice. Neuroscience (2012) 1.17
Melanocortin-4 receptor gene and physical activity in the Québec Family Study. Int J Obes (Lond) (2005) 1.15
Rgs 2 gene polymorphisms as modulators of anxiety in humans? J Neural Transm (Vienna) (2006) 1.14
Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity. Behav Brain Res (2010) 1.14
QTL underlying voluntary exercise in mice: interactions with the "mini muscle" locus and sex. J Hered (2009) 1.12
Can we modify the intrauterine environment to halt the intergenerational cycle of obesity? Int J Environ Res Public Health (2012) 1.11
Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiol Genomics (2011) 1.10
Integration of feeding and spontaneous physical activity: role for orexin. Physiol Behav (2006) 1.09
Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk. FASEB J (2010) 1.09
Endurance factors improve hippocampal neurogenesis and spatial memory in mice. Learn Mem (2011) 1.07
Genetic factors in physical activity and the equal environment assumption-- the Swedish young male twins study. Behav Genet (2006) 1.07
Complex genetics of obesity in mouse models. Annu Rev Nutr (2008) 1.06
Genetic variation in the pleiotropic association between physical activity and body weight in mice. Genet Sel Evol (2009) 1.05
Heritable germline epimutation is not the same as transgenerational epigenetic inheritance. Nat Genet (2007) 1.04
The evolution of marathon running : capabilities in humans. Sports Med (2007) 1.03
Genomic predictors of trainability. Exp Physiol (2011) 1.02
Differences in muscle and adipose tissue gene expression and cardio-metabolic risk factors in the members of physical activity discordant twin pairs. PLoS One (2010) 1.02
Genetics of physical activity and physical inactivity in humans. Behav Genet (2012) 1.02
Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02
Phenotypic and evolutionary plasticity of organ masses in response to voluntary exercise in house mice. Integr Comp Biol (2005) 1.01
Colorectal cancer survivorship: movement matters. Cancer Prev Res (Phila) (2011) 1.01
Physical activity levels of high school students --- United States, 2010. MMWR Morb Mortal Wkly Rep (2011) 0.99
Two new behavioral QTLs, Emo4 and Reb1, map to mouse Chromosome 1: Congenic strains and candidate gene identification studies. Mamm Genome (2006) 0.97
Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity. Exerc Sport Sci Rev (2008) 0.97
Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM. J Hum Genet (2005) 0.97
Advances in exercise, fitness, and performance genomics in 2011. Med Sci Sports Exerc (2012) 0.97
Serious limitations of the QTL/microarray approach for QTL gene discovery. BMC Biol (2010) 0.95
Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year. Arch Gerontol Geriatr (2012) 0.95
Physical activity in the prevention and treatment of stroke. ISRN Neurol (2011) 0.94
Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain. Genetics (2012) 0.93
Genome-wide linkage scan for exercise participation in Dutch sibling pairs. Eur J Hum Genet (2007) 0.91
Sex hormone effects on physical activity levels: why doesn't Jane run as much as Dick? Sports Med (2011) 0.90
QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains. Mamm Genome (2010) 0.90
Genetic variation for body weight change in mice in response to physical exercise. BMC Genet (2009) 0.90
Evidence for epigenetic interactions for loci on mouse chromosome 1 regulating open field activity. Behav Genet (2008) 0.89
Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture. Physiol Genomics (2010) 0.89
A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice. BMC Genet (2010) 0.88
Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits. Genes Brain Behav (2011) 0.88
Leptin levels and body composition of mice selectively bred for high voluntary locomotor activity. Physiol Biochem Zool (2007) 0.88
Erythropoietin elevates VO2,max but not voluntary wheel running in mice. J Exp Biol (2010) 0.87
A muscular twist on the fate of fat. N Engl J Med (2012) 0.86
Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance. Endocrinology (2005) 0.86
Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program. Nutr Metab (Lond) (2011) 0.83
Plasma adiponectin is increased in mice selectively bred for high wheel-running activity, but not by wheel running per sé. Horm Metab Res (2007) 0.83
Exercise and the cardiovascular system. Cardiol Res Pract (2012) 0.83
Effect of hyperthyroidism on spontaneous physical activity and energy expenditure in rats. J Appl Physiol (1985) (2003) 0.81
High-resolution mapping of a novel genetic locus regulating voluntary physical activity in mice. Genes Brain Behav (2011) 0.79
Primary prevention of CVD: physical activity. BMJ Clin Evid (2009) 0.76
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors. Proc Natl Acad Sci U S A (2010) 6.10
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
Collateral density, remodeling, and VEGF-A expression differ widely between mouse strains. Physiol Genomics (2007) 2.46
Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol (1985) (2010) 1.88
An efficient Bayesian model selection approach for interacting quantitative trait loci models with many effects. Genetics (2007) 1.82
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease. Genome Biol (2009) 1.77
Pleiotropy of quantitative trait loci for organ weights and limb bone lengths in mice. Physiol Genomics (2002) 1.57
Quantitative trait loci for physical activity traits in mice. Physiol Genomics (2008) 1.45
A large-sample QTL study in mice: I. Growth. Mamm Genome (2004) 1.43
Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice. Bone (2013) 1.40
A large-sample QTL study in mice: II. Body composition. Mamm Genome (2004) 1.31
Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics (2010) 1.30
Bayesian analyses of multiple epistatic QTL models for body weight and body composition in mice. Genet Res (2006) 1.24
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2. Physiol Genomics (2005) 1.19
An epistatic genetic basis for physical activity traits in mice. J Hered (2008) 1.19
Bayesian mapping of genomewide interacting quantitative trait loci for ordinal traits. Genetics (2007) 1.17
Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity. Behav Brain Res (2010) 1.14
QTL underlying voluntary exercise in mice: interactions with the "mini muscle" locus and sex. J Hered (2009) 1.12
Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice. Genome Biol (2014) 1.10
The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice. Evol Dev (2006) 1.10
A large-sample QTL study in mice: III. Reproduction. Mamm Genome (2004) 1.08
Genomic mapping of direct and correlated responses to long-term selection for rapid growth rate in mice. Genetics (2005) 1.08
Importance of randomization in microarray experimental designs with Illumina platforms. Nucleic Acids Res (2009) 1.06
Genetic variation in the pleiotropic association between physical activity and body weight in mice. Genet Sel Evol (2009) 1.05
Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02
Voluntary exercise and its effects on body composition depend on genetic selection history. Obesity (Silver Spring) (2009) 0.99
EST-based gene discovery in pig: virtual expression patterns and comparative mapping to human. Mamm Genome (2003) 0.98
Characterization of QTL with major effects on fatness and growth on mouse chromosome 2. Obes Res (2004) 0.96
Fine mapping of "mini-muscle," a recessive mutation causing reduced hindlimb muscle mass in mice. J Hered (2008) 0.95
The M16 mouse: an outbred animal model of early onset polygenic obesity and diabesity. Obes Res (2004) 0.95
Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain. Genetics (2012) 0.93
The use of plasmodes as a supplement to simulations: A simple example evaluating individual admixture estimation methodologies. Comput Stat Data Anal (2009) 0.92
Phenotypic effects of the "mini-muscle" allele in a large HR x C57BL/6J mouse backcross. J Hered (2008) 0.91
Genetic variation for body weight change in mice in response to physical exercise. BMC Genet (2009) 0.90
Genotype X diet interactions in mice predisposed to mammary cancer. I. Body weight and fat. Mamm Genome (2008) 0.89
Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture. Physiol Genomics (2010) 0.89
A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice. BMC Genet (2010) 0.88
Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression. Clin Exp Metastasis (2010) 0.88
Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis. Mamm Genome (2008) 0.87
Exercise and diet affect quantitative trait loci for body weight and composition traits in an advanced intercross population of mice. Physiol Genomics (2012) 0.86
Microarray profiling for differential gene expression in ovaries and ovarian follicles of pigs selected for increased ovulation rate. Genetics (2004) 0.86
Evaluation of hypothalamic gene expression in mice divergently selected for heat loss. Physiol Genomics (2003) 0.85
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis. Clin Exp Metastasis (2010) 0.85
Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. Environ Health Perspect (2009) 0.84
Generation and sequence characterization of a normalized cDNA library from swine ovarian follicles. Mamm Genome (2003) 0.84
High-resolution comparative mapping of pig Chromosome 4, emphasizing the FAT1 region. Mamm Genome (2004) 0.84
Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice. Front Genet (2011) 0.84
Advances in comparative genetics: influence of genetics on obesity. Br J Nutr (2011) 0.83
Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology. J Bone Miner Res (2011) 0.83
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. Am J Physiol Endocrinol Metab (2008) 0.82
Genomic mapping of social behavior traits in a F2 cross derived from mice selectively bred for high aggression. BMC Genet (2010) 0.81
Epistatic interactions of genes influence within-individual variation of physical activity traits in mice. Genetica (2011) 0.80
Fine mapping of mouse QTLs for fatness using SNP data. OMICS (2007) 0.78
The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype. Trends Endocrinol Metab (2015) 0.78
Genetic variance and covariance patterns for body weight and energy balance characters in an advanced intercross population of mice. Genet Sel Evol (2005) 0.78
Patterns of cellular gene expression in cells infected with cytopathic or non-cytopathic bovine viral diarrhea virus. Anim Biotechnol (2003) 0.77
Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data. BMC Genomics (2012) 0.77
Rescue of the mouse DDK syndrome by parent-of-origin-dependent modifiers. Biol Reprod (2006) 0.77
Mapping interacting QTL for count phenotypes using hierarchical Poisson and binomial models: an application to reproductive traits in mice. Genet Res (Camb) (2010) 0.76
QTL analysis in livestock. Methods Mol Biol (2002) 0.75
Differential expression of NAT1 translational repressor during development of bovine intramuscular adipocytes. Physiol Genomics (2002) 0.75