PubRank

Denis C Shields

Author PubWeight™ 76.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SLiMFinder: a probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins. PLoS One 2007 2.55
2 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet 2012 2.53
3 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2010 2.15
4 Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet 2009 2.04
5 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet 2012 1.96
6 CompariMotif: quick and easy comparisons of sequence motifs. Bioinformatics 2008 1.82
7 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
8 Bioinformatic discovery of novel bioactive peptides. Nat Chem Biol 2007 1.72
9 SLiMDisc: short, linear motif discovery, correcting for common evolutionary descent. Nucleic Acids Res 2006 1.61
10 Blood pressure loci identified with a gene-centric array. Am J Hum Genet 2011 1.44
11 A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet 2011 1.43
12 SLiMSearch 2.0: biological context for short linear motifs in proteins. Nucleic Acids Res 2011 1.23
13 Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin Cell Dev Biol 2012 1.19
14 Wrapping up BLAST and other applications for use on Unix clusters. Bioinformatics 2003 1.17
15 Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery. Bioinformatics 2009 1.17
16 Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). J Lipid Res 2012 1.17
17 Tandem repeat copy-number variation in protein-coding regions of human genes. Genome Biol 2005 1.16
18 The SLiMDisc server: short, linear motif discovery in proteins. Nucleic Acids Res 2007 1.16
19 Significantly different patterns of amino acid replacement after gene duplication as compared to after speciation. Mol Biol Evol 2003 1.16
20 Prediction of short linear protein binding regions. J Mol Biol 2011 1.14
21 Human tissue profiling with multidimensional protein identification technology. J Proteome Res 2005 1.07
22 SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions. Nucleic Acids Res 2012 1.04
23 Interactome-wide prediction of short, disordered protein interaction motifs in humans. Mol Biosyst 2011 1.03
24 SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs. Nucleic Acids Res 2010 1.02
25 GASP: Gapped Ancestral Sequence Prediction for proteins. BMC Bioinformatics 2004 1.01
26 A genome-wide association study of recipient genotype and medium-term kidney allograft function. Clin Transplant 2013 1.00
27 Computational identification and analysis of protein short linear motifs. Front Biosci (Landmark Ed) 2010 1.00
28 Approved drug mimics of short peptide ligands from protein interaction motifs. J Chem Inf Model 2008 0.98
29 Insider access: pepducin symposium explores a new approach to GPCR modulation. Ann N Y Acad Sci 2009 0.96
30 Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins. BMC Bioinformatics 2010 0.95
31 Predicting the important enzymes in human breast milk digestion. J Agric Food Chem 2014 0.92
32 BADASP: predicting functional specificity in protein families using ancestral sequences. Bioinformatics 2005 0.91
33 Optimal stepwise experimental design for pairwise functional interaction studies. Bioinformatics 2008 0.90
34 Towards the improved discovery and design of functional peptides: common features of diverse classes permit generalized prediction of bioactivity. PLoS One 2012 0.89
35 Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians. BMC Med Genet 2005 0.88
36 Meta-analysis to test the association of HIV-1 nef amino acid differences and deletions with disease progression. J Virol 2010 0.88
37 Predicting binding within disordered protein regions to structurally characterised peptide-binding domains. PLoS One 2013 0.87
38 EnzymePredictor: a tool for predicting and visualizing enzymatic cleavages of digested proteins. J Proteome Res 2012 0.85
39 Tools for the identification of variable and potentially variable tandem repeats. BMC Genomics 2006 0.84
40 Marked variability in the extent of protein disorder within and between viral families. PLoS One 2013 0.84
41 Profile-based short linear protein motif discovery. BMC Bioinformatics 2012 0.83
42 Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins. PLoS One 2012 0.83
43 Evolution of the isoelectric point of mammalian proteins as a consequence of indels and adaptive evolution. Proteins 2011 0.83
44 Peptide-binding domains: are limp handshakes safest? Sci Signal 2012 0.83
45 Platelet glycoprotein Ib alpha receptor polymorphisms and recurrent ischaemic events in acute coronary syndrome patients. J Thromb Thrombolysis 2002 0.82
46 Following the digestion of milk proteins from mother to baby. J Proteome Res 2014 0.82
47 Genetic stratification of pathogen-response-related and other variants within a homogeneous Caucasian Irish population. Eur J Hum Genet 2005 0.82
48 Discovery of small molecule inhibitors of protein-protein interactions using combined ligand and target score normalization. J Chem Inf Model 2009 0.81
49 The impact of genetic variation in the region of the GPIIIa gene, on Pl expression bias and GPIIb/IIIa receptor density in platelets. Br J Haematol 2006 0.81
50 CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids. J Chem Inf Model 2011 0.81
51 Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes. BMC Med Genet 2004 0.81
52 Uroplakin III is not a major candidate gene for primary vesicoureteral reflux. Eur J Hum Genet 2005 0.81
53 CPPpred: prediction of cell penetrating peptides. Bioinformatics 2013 0.81
54 Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif. ACS Chem Biol 2009 0.81
55 Evaluation of whether accelerated protein evolution in chordates has occurred before, after, or simultaneously with gene duplication. Mol Biol Evol 2006 0.80
56 Molecular evolution of CXC chemokines and receptors. Trends Immunol 2003 0.80
57 Absolute net charge and the biological activity of oligopeptides. J Chem Inf Model 2006 0.79
58 Platelet signalling networks: pathway perturbation demonstrates differential sensitivity of ADP secretion and fibrinogen binding. Platelets 2011 0.79
59 A polymorphism in ACE2 is associated with a lower risk for fatal cardiovascular events in females: the MORGAM project. J Renin Angiotensin Aldosterone Syst 2011 0.79
60 SCL-Epred: a generalised de novo eukaryotic protein subcellular localisation predictor. Amino Acids 2013 0.79
61 Shift in the isoelectric-point of milk proteins as a consequence of adaptive divergence between the milks of mammalian species. Biol Direct 2011 0.78
62 Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides. Food Chem 2013 0.78
63 SLiMScape: a protein short linear motif analysis plugin for Cytoscape. BMC Bioinformatics 2013 0.78
64 Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients. Transplantation 2007 0.78
65 Improved database searches for orthologous sequences by conditioning on outgroup sequences. Bioinformatics 2002 0.78
66 Marked variation in predicted and observed variability of tandem repeat loci across the human genome. BMC Genomics 2008 0.78
67 Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations. Eur J Hum Genet 2005 0.77
68 PeptideLocator: prediction of bioactive peptides in protein sequences. Bioinformatics 2013 0.77
69 Differences in the number of intrinsically disordered regions between yeast duplicated proteins, and their relationship with functional divergence. PLoS One 2011 0.76
70 Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease. Blood 2002 0.76
71 Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs. BMC Syst Biol 2011 0.75
72 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest 2017 0.75
73 A sequence sub-sampling algorithm increases the power to detect distant homologues. Nucleic Acids Res 2005 0.75
74 Identification of potential small molecule peptidomimetics similar to motifs in proteins. J Chem Inf Model 2007 0.75
75 Web server to identify similarity of amino acid motifs to compounds (SAAMCO). J Chem Inf Model 2008 0.75
76 In silico protein motif discovery and structural analysis. Methods Mol Biol 2011 0.75
77 Computational approaches to developing short cyclic peptide modulators of protein-protein interactions. Methods Mol Biol 2015 0.75
78 Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet 2017 0.75
79 Correlation of disorder between S. cerevisiae interacting proteins. Mol Biosyst 2011 0.75