Published in J Neurosci Res on February 15, 2009
Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery. PLoS One (2015) 1.45
Immunologic privilege in the central nervous system and the blood-brain barrier. J Cereb Blood Flow Metab (2012) 1.30
The neurovascular unit, matrix proteases, and innate inflammation. Ann N Y Acad Sci (2010) 1.25
Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke. Dev Neurobiol (2011) 1.18
The role of the microcirculation in delayed cerebral ischemia and chronic degenerative changes after subarachnoid hemorrhage. J Cereb Blood Flow Metab (2013) 1.18
Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. J Cereb Blood Flow Metab (2011) 1.17
The role of the cerebral capillaries in acute ischemic stroke: the extended penumbra model. J Cereb Blood Flow Metab (2013) 1.12
Monocyte chemoattractant protein-1 and the blood-brain barrier. Cell Mol Life Sci (2013) 1.02
Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia. Br J Pharmacol (2014) 0.98
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun (2014) 0.94
The central role of aquaporins in the pathophysiology of ischemic stroke. Front Cell Neurosci (2015) 0.93
Ultrastructural analysis of blood-brain barrier breakdown in the peri-infarct zone in young adult and aged mice. J Cereb Blood Flow Metab (2015) 0.82
Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes. Brain Res (2013) 0.80
Hemostasis and alterations of the central nervous system. Semin Thromb Hemost (2013) 0.79
Aging and the neurovascular unit. Ann N Y Acad Sci (2012) 0.79
Mannitol induces selective astroglial death in the CA1 region of the rat hippocampus following status epilepticus. BMB Rep (2015) 0.79
Compromised blood-brain barrier competence in remote brain areas in ischemic stroke rats at the chronic stage. J Comp Neurol (2014) 0.79
Levo-tetrahydropalmatine attenuates mouse blood-brain barrier injury induced by focal cerebral ischemia and reperfusion: Involvement of Src kinase. Sci Rep (2015) 0.78
Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS One (2013) 0.76
Mean transit time on Aquilion ONE and its utilization in patients undergoing acute stroke intervention. J Vasc Interv Neurol (2014) 0.75
Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci (2004) 9.29
Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci (2003) 6.53
Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke (1995) 6.49
Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol (2007) 6.15
The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis (2004) 5.49
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci (2001) 4.99
Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke (1998) 3.58
Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem (1994) 3.37
Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J Cereb Blood Flow Metab (2000) 3.04
Matrix metalloproteinases increase very early during experimental focal cerebral ischemia. J Cereb Blood Flow Metab (1999) 2.41
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke. Stroke (2006) 2.27
Proteolytic cascade enzymes increase in focal cerebral ischemia in rat. J Cereb Blood Flow Metab (1996) 1.99
Focal cerebral ischemia induces active proteases that degrade microvascular matrix. Stroke (2004) 1.81
A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell (2004) 1.73
Integrin-matrix interactions in the cerebral microvasculature. Arterioscler Thromb Vasc Biol (2006) 1.72
Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke (1995) 1.71
Free radicals as triggers of brain edema formation after stroke. Free Radic Biol Med (2005) 1.62
Time course of aquaporin expression after transient focal cerebral ischemia in mice. J Neurosci Res (2006) 1.56
Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke. Stroke (2007) 1.47
Rapid loss of microvascular integrin expression during focal brain ischemia reflects neuron injury. J Cereb Blood Flow Metab (2001) 1.37
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia. J Cereb Blood Flow Metab (2003) 1.28
Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion. Stroke (1997) 1.28
Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure. Stroke (2003) 0.94
Preconditioning with chronic cerebral hypoperfusion reduces a focal cerebral ischemic injury and increases apurinic/apyrimidinic endonuclease/redox factor-1 and matrix metalloproteinase-2 expression. Curr Neurovasc Res (2007) 0.88
Microvascular basal lamina damage in thromboembolic stroke in a rat model. Neurosci Lett (2003) 0.84
Acute tissue response to cerebral ischemia in the gerbil. An ultrastructural study. J Neurol Sci (1977) 0.83
Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association. Stroke (2003) 4.13
Long-term mortality in patients with stroke of undetermined etiology. Stroke (2012) 3.38
Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome. BMC Neurol (2004) 2.30
Stroke statistics in Korea: part I. Epidemiology and risk factors: a report from the korean stroke society and clinical research center for stroke. J Stroke (2013) 2.19
Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke (2007) 2.10
Serum alkaline phosphatase and phosphate in cerebral atherosclerosis and functional outcomes after cerebral infarction. Stroke (2013) 2.05
An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis. J Neuroimmunol (2003) 1.97
Focal cerebral ischemia induces active proteases that degrade microvascular matrix. Stroke (2004) 1.81
Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev (2014) 1.76
Iron overload accelerates bone loss in healthy postmenopausal women and middle-aged men: a 3-year retrospective longitudinal study. J Bone Miner Res (2012) 1.63
Responses of endothelial cell and astrocyte matrix-integrin receptors to ischemia mimic those observed in the neurovascular unit. Stroke (2007) 1.58
Simple microwire and microcatheter mechanical thrombolysis with adjuvant intraarterial urokinase for treatment of hyperacute ischemic stroke patients. Acta Radiol (2008) 1.56
Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia? Comp Med (2008) 1.48
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res (2006) 1.47
Safety and outcome after thrombolytic treatment in ischemic stroke patients with high-risk cardioembolic sources and prior subtherapeutic warfarin use. J Neurol Sci (2010) 1.43
Stroke severity in concomitant cardiac sources of embolism in patients with atrial fibrillation. J Neurol Sci (2010) 1.38
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia. J Cereb Blood Flow Metab (2003) 1.28
Middle cerebral artery stenosis is a major clinical determinant in striatocapsular small, deep infarction. Arch Neurol (2002) 1.23
Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia. Mol Cell Neurosci (2008) 1.20
Stroke awareness decreases prehospital delay after acute ischemic stroke in Korea. BMC Neurol (2011) 1.18
Left atrial appendage thrombi in stroke patients: detection with two-phase cardiac CT angiography versus transesophageal echocardiography. Radiology (2009) 1.18
Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by β(1)-integrins. J Cereb Blood Flow Metab (2011) 1.17
Coxiella burnetii in bulk tank milk samples, United States. Emerg Infect Dis (2005) 1.17
Improved time intervals by implementation of computerized physician order entry-based stroke team approach. Cerebrovasc Dis (2006) 1.17
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J Cell Biochem (2008) 1.16
A new subtype classification of ischemic stroke based on treatment and etiologic mechanism. Eur Neurol (2006) 1.16
Effects of alpha-lipoic Acid on body weight in obese subjects. Am J Med (2011) 1.15
(-)-alpha-Isosparteine copper(II) diazide. Acta Crystallogr C (2002) 1.15
Transmodulation between phospholipase D and c-Src enhances cell proliferation. Mol Cell Biol (2003) 1.15
Models of focal cerebral ischemia in the nonhuman primate. ILAR J (2003) 1.12
Stroke Statistics in Korea: Part II Stroke Awareness and Acute Stroke Care, A Report from the Korean Stroke Society and Clinical Research Center For Stroke. J Stroke (2013) 1.11
Red blood cell distribution width is associated with poor clinical outcome in acute cerebral infarction. Thromb Haemost (2012) 1.10
Detection of thrombus in acute ischemic stroke: value of thin-section noncontrast-computed tomography. Stroke (2005) 1.09
Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells. Neuro Oncol (2012) 1.09
The rapid decrease in astrocyte-associated dystroglycan expression by focal cerebral ischemia is protease-dependent. J Cereb Blood Flow Metab (2007) 1.08
Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha5beta1 and alphavbeta5. J Immunol (2007) 1.05
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res (2007) 1.05
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells. Free Radic Biol Med (2009) 1.04
Involvement of c-Src kinase in the regulation of TGF-beta1-induced apoptosis. Oncogene (2004) 1.03
Use of gel zymography to examine matrix metalloproteinase (gelatinase) expression in brain tissue or in primary glial cultures. Methods Mol Biol (2012) 1.03
Sequential combination of intravenous recombinant tissue plasminogen activator and intra-arterial urokinase in acute ischemic stroke. AJNR Am J Neuroradiol (2004) 1.03
Impaired fasting glucose and risk of cardiovascular disease in Korean men and women: the Korean Heart Study. Diabetes Care (2012) 1.02
Public awareness of stroke in Korea: a population-based national survey. Stroke (2011) 1.01
Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis. J Neurol Sci (2004) 1.00
Focal cerebral ischemia preferentially affects neurons distant from their neighboring microvessels. J Cereb Blood Flow Metab (2005) 0.98
Dual-enhanced cardiac CT for detection of left atrial appendage thrombus in patients with stroke: a prospective comparison study with transesophageal echocardiography. Stroke (2011) 0.98
Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation. Carcinogenesis (2013) 0.98
New options in anticoagulation for atrial fibrillation. N Engl J Med (2011) 0.97
The frequency and risk of preclinical coronary artery disease detected using multichannel cardiac computed tomography in patients with ischemic stroke. Cerebrovasc Dis (2012) 0.97
Polyphenolic extract isolated from Korean Lonicera japonica Thunb. induce G2/M cell cycle arrest and apoptosis in HepG2 cells: involvements of PI3K/Akt and MAPKs. Food Chem Toxicol (2012) 0.97
NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia. J Biol Chem (2010) 0.96
Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program. Stroke (2009) 0.96
Different prognostic value of white blood cell subtypes in patients with acute cerebral infarction. Atherosclerosis (2012) 0.95
Brachial-ankle pulse wave velocity is a strong predictor for mortality in patients with acute stroke. Hypertension (2014) 0.94
Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure. Stroke (2003) 0.94
Development of smartphone application that aids stroke screening and identifying nearby acute stroke care hospitals. Yonsei Med J (2014) 0.93
Incidence of embolism associated with carotid artery stenting: open-cell versus closed-cell stents. J Neurosurg (2013) 0.93
Frequency and significance of cardiac sources of embolism in the TOAST classification. Cerebrovasc Dis (2007) 0.93
Patent foramen ovale: diagnosis with multidetector CT--comparison with transesophageal echocardiography. Radiology (2008) 0.92
Cocrystallization of melaminium levulinate monohydrate. Acta Crystallogr C (2004) 0.92
Wingspan stenting for intracranial atherosclerotic stenosis: clinical outcomes and risk factors for in-stent restenosis. Neurosurgery (2013) 0.92
Association of metabolically healthy obesity with subclinical coronary atherosclerosis in a Korean population. Obesity (Silver Spring) (2014) 0.91
Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation. Neuro Oncol (2011) 0.91
Circadian rhythm of serum vaspin in healthy male volunteers: relation to meals. J Clin Endocrinol Metab (2010) 0.91
Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum. J Vet Sci (2004) 0.91
Regulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from Korea Lonicera japonica THUNB. Evid Based Complement Alternat Med (2012) 0.90
Stroke units and stroke care services in Korea. Int J Stroke (2012) 0.90
Mechanism of medullary infarction based on arterial territory involvement. J Clin Neurol (2012) 0.90
An objective pronator drift test application (iPronator) using handheld device. PLoS One (2012) 0.89
Recanalization and stroke outcome. Circulation (2007) 0.89
Ischemic stroke: measurement of intracranial artery calcifications can improve prediction of asymptomatic coronary artery disease. Radiology (2013) 0.89
Interarm blood pressure difference and mortality in patients with acute ischemic stroke. Neurology (2013) 0.88
Simplified clinical risk score to predict acute kidney injury after aortic surgery. J Cardiothorac Vasc Anesth (2013) 0.88
Preconditioning with chronic cerebral hypoperfusion reduces a focal cerebral ischemic injury and increases apurinic/apyrimidinic endonuclease/redox factor-1 and matrix metalloproteinase-2 expression. Curr Neurovasc Res (2007) 0.88
The prevalence of peripheral arterial disease in korean patients with type 2 diabetes mellitus attending a university hospital. Diabetes Metab J (2011) 0.88
Paxilline enhances TRAIL-mediated apoptosis of glioma cells via modulation of c-FLIP, survivin and DR5. Exp Mol Med (2011) 0.88
The risk of incident type 2 diabetes in a Korean metabolically healthy obese population: the role of systemic inflammation. J Clin Endocrinol Metab (2014) 0.87
Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation. Carcinogenesis (2009) 0.86
Cardiac computed tomographic angiography for detection of cardiac sources of embolism in stroke patients. Stroke (2009) 0.86
Chronic cerebral hypoperfusion protects against acute focal ischemia, improves motor function, and results in vascular remodeling. Curr Neurovasc Res (2008) 0.86
Cigarette smoke promotes eosinophilic inflammation, airway remodeling, and nasal polyps in a murine polyp model. Am J Rhinol Allergy (2014) 0.85
Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling. EMBO J (2011) 0.85
Prediction of long-term outcome by percent improvement after the first day of thrombolytic treatment in stroke patients. J Neurol Sci (2009) 0.85
Vestibular imbalance associated with a lesion in the nucleus prepositus hypoglossi area. Arch Neurol (2004) 0.85
Vitamin C induces apoptosis in AGS cells by down-regulation of 14-3-3σ via a mitochondrial dependent pathway. Food Chem (2012) 0.85
Increases in cerebral atherosclerosis according to CHADS2 scores in patients with stroke with nonvalvular atrial fibrillation. Stroke (2011) 0.85
Induction of the cell cycle arrest and apoptosis by flavonoids isolated from Korean Citrus aurantium L. in non-small-cell lung cancer cells. Food Chem (2012) 0.85
Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes. Exp Mol Med (2012) 0.85
Label-free quantification for discovering novel biomarkers in the diagnosis and assessment of disease activity in inflammatory bowel disease. J Dig Dis (2013) 0.84
4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease. J Alzheimers Dis (2011) 0.84
Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage. J Gastroenterol (2015) 0.83
Decreased expression of sirtuin 6 is associated with release of high mobility group box-1 after cerebral ischemia. Biochem Biophys Res Commun (2013) 0.83
Cortex-sparing infarctions in patients with occlusion of the middle cerebral artery. J Neurol Neurosurg Psychiatry (2010) 0.83
Transoesophageal echocardiography in patients with acute stroke with sinus rhythm and no cardiac disease history. J Neurol Neurosurg Psychiatry (2009) 0.83