Published in J Am Chem Soc on October 08, 2008
The N-terminus of the intrinsically disordered protein α-synuclein triggers membrane binding and helix folding. Biophys J (2010) 1.39
Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains. Biophys J (2012) 1.13
Phase behavior and domain size in sphingomyelin-containing lipid bilayers. Biochim Biophys Acta (2013) 1.12
The molecular structure of the liquid-ordered phase of lipid bilayers. J Am Chem Soc (2014) 1.05
CHARMM all-atom additive force field for sphingomyelin: elucidation of hydrogen bonding and of positive curvature. Biophys J (2014) 1.03
Hexagonal Substructure and Hydrogen Bonding in Liquid-Ordered Phases Containing Palmitoyl Sphingomyelin. Biophys J (2015) 0.92
An NMR database for simulations of membrane dynamics. Biochim Biophys Acta (2010) 0.91
Phase-separation and domain-formation in cholesterol-sphingomyelin mixture: pulse-EPR oxygen probing. Biophys J (2011) 0.90
Solid-state ¹³C NMR reveals annealing of raft-like membranes containing cholesterol by the intrinsically disordered protein α-Synuclein. J Mol Biol (2013) 0.89
Using spin-label W-band EPR to study membrane fluidity profiles in samples of small volume. J Magn Reson (2012) 0.89
Phase separation in binary mixtures of bipolar and monopolar lipid dispersions revealed by 2H NMR spectroscopy, small angle x-ray scattering, and molecular theory. Biophys J (2009) 0.88
Phases and domains in sphingomyelin-cholesterol membranes: structure and properties using EPR spin-labeling methods. Eur Biophys J (2011) 0.88
The Affinity of Cholesterol for Different Phospholipids Affects Lateral Segregation in Bilayers. Biophys J (2016) 0.87
Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state. Biophys J (2012) 0.87
Detailed comparison of deuterium quadrupole profiles between sphingomyelin and phosphatidylcholine bilayers. Biophys J (2014) 0.86
Cholesterol's aliphatic side chain modulates membrane properties. Angew Chem Int Ed Engl (2013) 0.85
Deuterium NMR of raft model membranes reveals domain-specific order profiles and compositional distribution. Biophys J (2015) 0.82
Dynamics and ordering of lipid spin-labels along the coexistence curve of two membrane phases: an ESR study. Chem Phys Lipids (2012) 0.81
Structure and dynamics of the myristoyl lipid modification of SRC peptides determined by 2H solid-state NMR spectroscopy. Biophys J (2009) 0.80
Orientation and Order of the Amide Group of Sphingomyelin in Bilayers Determined by Solid-State NMR. Biophys J (2015) 0.80
Area per lipid and cholesterol interactions in membranes from separated local-field (13)C NMR spectroscopy. Biophys J (2014) 0.79
Critical behaviour in DOPC/DPPC/cholesterol mixtures: static (2)H NMR line shapes near the critical point. Biophys J (2014) 0.79
Hydrogen bonding of cholesterol in the lipidic cubic phase. Langmuir (2013) 0.77
Lipid Interactions and Organization in Complex Bilayer Membranes. Biophys J (2016) 0.77
Selective deuterium labeling of the sphingoid backbone: facile syntheses of 3,4,5-trideuterio-d-erythro-sphingosine and 3-deuterio-d-erythro-sphingomyelin. Chem Phys Lipids (2010) 0.77
Elastic deformation and area per lipid of membranes: atomistic view from solid-state deuterium NMR spectroscopy. Biochim Biophys Acta (2014) 0.76
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy. Oncotarget (2016) 0.76
Cholesterol-induced suppression of membrane elastic fluctuations at the atomistic level. Chem Phys Lipids (2016) 0.75
Functional rafts in cell membranes. Nature (1997) 38.89
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell (1992) 17.81
The state of lipid rafts: from model membranes to cells. Annu Rev Biophys Biomol Struct (2003) 8.51
Model systems, lipid rafts, and cell membranes. Annu Rev Biophys Biomol Struct (2004) 7.52
Phase equilibria in the phosphatidylcholine-cholesterol system. Biochim Biophys Acta (1987) 7.38
Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophys J (2003) 6.88
Lecithin bilayers. Density measurement and molecular interactions. Biophys J (1978) 6.10
Physical properties of the fluid lipid-bilayer component of cell membranes: a perspective. Q Rev Biophys (1991) 5.96
Lipid rafts: at a crossroad between cell biology and physics. Nat Cell Biol (2007) 5.17
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nat Cell Biol (1999) 4.94
Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts. Biophys J (2003) 4.48
Lipid raft microdomains and neurotransmitter signalling. Nat Rev Neurosci (2006) 3.69
Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes? Biochem Biophys Res Commun (1997) 3.67
Area per lipid and acyl length distributions in fluid phosphatidylcholines determined by (2)H NMR spectroscopy. Biophys J (2000) 3.54
Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J (1998) 3.22
The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases. J Immunol (1992) 3.05
Miscibility phase diagrams of giant vesicles containing sphingomyelin. Phys Rev Lett (2005) 2.86
Lipid traffic in animal cells. Annu Rev Cell Biol (1989) 2.78
Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains. J Biol Chem (1998) 2.78
Interaction of cholesterol with various glycerophospholipids and sphingomyelin. Biochemistry (1990) 2.77
Spectroscopic studies of specifically deuterium labeled membrane systems. Nuclear magnetic resonance investigation of the effects of cholesterol in model systems. Biochemistry (1978) 2.71
Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation. Nat Immunol (2000) 2.59
Plasma membranes contain half the phospholipid and 90% of the cholesterol and sphingomyelin in cultured human fibroblasts. J Biol Chem (1989) 2.57
Phospholipid component volumes: determination and application to bilayer structure calculations. Biophys J (1998) 2.54
Determination of component volumes of lipid bilayers from simulations. Biophys J (1997) 2.37
Theory of thermal anomalies in the specific heat of lipid bilayers containing cholesterol. Biophys J (1989) 2.24
Critical fluctuations in domain-forming lipid mixtures. Proc Natl Acad Sci U S A (2007) 2.16
Influence of docosahexaenoic acid and cholesterol on lateral lipid organization in phospholipid mixtures. Biochemistry (1998) 2.12
Sphingomyelins in bilayers and biological membranes. Biochim Biophys Acta (1980) 2.07
What's so special about cholesterol? Lipids (2004) 1.98
How principles of domain formation in model membranes may explain ambiguities concerning lipid raft formation in cells. Biochim Biophys Acta (2005) 1.90
Molecular order and dynamics of phosphatidylcholine bilayer membranes in the presence of cholesterol, ergosterol and lanosterol: a comparative study using 2H-, 13C- and 31P-NMR spectroscopy. Biochim Biophys Acta (1995) 1.84
Influence of cholesterol on the polar region of phosphatidylcholine and phosphatidylethanolamine bilayers. Biochemistry (1978) 1.76
Nonideal mixing of phosphatidylserine and phosphatidylcholine in the fluid lamellar phase. Biophys J (1993) 1.70
Molecular-level organization of saturated and polyunsaturated fatty acids in a phosphatidylcholine bilayer containing cholesterol. Biochemistry (2004) 1.62
Universal behavior of membranes with sterols. Biophys J (2005) 1.57
Simulation of the early stages of nano-domain formation in mixed bilayers of sphingomyelin, cholesterol, and dioleylphosphatidylcholine. Biophys J (2004) 1.55
Lipid bilayers, NMR relaxation, and computer simulations. Acc Chem Res (2002) 1.52
A structural model for the cholesterol-phosphatidylcholine complexes in bilayer membranes. Lipids (1977) 1.50
Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chem Phys Lipids (2004) 1.42
A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems. Biophys J (2002) 1.35
Anisotropic motion and molecular dynamics of cholesterol, lanosterol, and ergosterol in lecithin bilayers studied by quasi-elastic neutron scattering. Biochemistry (2002) 1.34
Thermodynamics of membrane domains. Biochim Biophys Acta (2006) 1.33
Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation. Biophys J (2002) 1.31
Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. J Am Chem Soc (2006) 1.29
Monte Carlo simulation of two-component bilayers: DMPC/DSPC mixtures. Biophys J (1999) 1.29
Cholesterol dynamics in membranes of raft composition: a molecular point of view from 2H and 31P solid-state NMR. Biochemistry (2003) 1.28
Phase behavior of lipid mixtures. Nat Chem Biol (2006) 1.27
Fluorescent probes alter miscibility phase boundaries in ternary vesicles. J Phys Chem B (2007) 1.26
Role of cholesterol in formation and function of a signaling complex involving alphavbeta3, integrin-associated protein (CD47), and heterotrimeric G proteins. J Cell Biol (1999) 1.26
Characterization of the ternary mixture of sphingomyelin, POPC, and cholesterol: support for an inhomogeneous lipid distribution at high temperatures. Biophys J (2008) 1.23
Docosahexaenoic acid enhances segregation of lipids between : 2H-NMR study. Biophys J (2008) 1.20
Structure of docosahexaenoic acid-containing phospholipid bilayers as studied by (2)H NMR and molecular dynamics simulations. J Am Chem Soc (2002) 1.17
Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. Biophys J (2004) 1.16
Interaction of cholesterol with a docosahexaenoic acid-containing phosphatidylethanolamine: trigger for microdomain/raft formation? Biochemistry (2003) 1.15
Sphingomyelin and ceramide as regulators of development and lifespan. Mech Ageing Dev (2001) 1.15
Use of cyclodextrin for AFM monitoring of model raft formation. Biophys J (2004) 1.11
Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine. Biophys J (2006) 1.11
Monounsaturated PE does not phase-separate from the lipid raft molecules sphingomyelin and cholesterol: role for polyunsaturation? Biochemistry (2002) 1.10
Sphingomyelin: biophysical aspects. Chem Phys Lipids (1999) 1.08
Fatty acid composition and thermal behavior of natural sphingomyelins. Biochim Biophys Acta (1979) 1.08
Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy. Biophys J (2005) 1.07
Rapid deconvolution of NMR powder spectra by weighted fast Fourier transformation. Solid State Nucl Magn Reson (1997) 1.07
Lanosterol and cholesterol-induced variations in bilayer elasticity probed by 2H NMR relaxation. Langmuir (2004) 1.06
Lipid lateral diffusion in bilayers with phosphatidylcholine, sphingomyelin and cholesterol. An NMR study of dynamics and lateral phase separation. Chem Phys Lipids (2006) 1.06
Differential effects of cholesterol, ergosterol and lanosterol on a dipalmitoyl phosphatidylcholine membrane: a molecular dynamics simulation study. J Phys Chem B (2007) 1.05
The origin of multiple quadrupole couplings in the deuterium NMR spectra of the 2 chain of 1,2 dipalmitoyl-sn-glycero-3-phosphorylcholine. FEBS Lett (1981) 1.05
Membrane rafts in host-pathogen interactions. Biochim Biophys Acta (2006) 1.04
Simulation of the gel-fluid transition in a membrane composed of lipids with two connected acyl chains: application of a dimer-move step. Biophys J (1996) 1.03
A (2)H NMR study of macroscopically aligned bilayer membranes containing interfacial hydroxyl residues. Biophys J (2000) 1.02
NMR elastometry of fluid membranes in the mesoscopic regime. Phys Rev E Stat Nonlin Soft Matter Phys (2002) 1.02
Ergosterol in POPC membranes: physical properties and comparison with structurally similar sterols. Biophys J (2006) 0.98
Molecular organization of cholesterol in polyunsaturated phospholipid membranes: a solid state 2H NMR investigation. FEBS Lett (1999) 0.92
Novel NMR tools to study structure and dynamics of biomembranes. Chem Phys Lipids (2002) 0.90
Methanolysis of sphingomyelin. Toward an epimerization-free methodology for the preparation of D-erythro-sphingosylphosphocholine. J Lipid Res (2000) 0.89
Hydration and lateral organization in phospholipid bilayers containing sphingomyelin: a 2H-NMR study. Biophys J (2003) 0.87
Controlling membrane cholesterol content. A role for polyunsaturated (docosahexaenoate) phospholipids. Biochemistry (2002) 0.85
Structural diversity of sphingomyelin microdomains. Ultramicroscopy (2004) 0.83
Float on: lipid rafts in the lifecycle of HIV. Front Biosci (2007) 0.82
Detection of unusual lipid mixing in cholesterol-rich phospholipid bilayers: the long and the short of it. J Am Chem Soc (2003) 0.82
Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes. Biophys J (2006) 2.23
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J (2010) 2.12
Selective caveolin-1-dependent endocytosis of glycosphingolipids. Mol Biol Cell (2003) 2.05
Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat Immunol (2011) 1.94
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37. Biochemistry (2004) 1.86
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. J Biol Chem (2007) 1.74
Two protonation switches control rhodopsin activation in membranes. Proc Natl Acad Sci U S A (2008) 1.74
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells. Cell Signal (2010) 1.73
Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study. J Biol Chem (2004) 1.73
Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol (2007) 1.72
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. J Clin Invest (2013) 1.72
Conformational energetics of rhodopsin modulated by nonlamellar-forming lipids. Biochemistry (2002) 1.71
BODIPY-cholesterol: a new tool to visualize sterol trafficking in living cells and organisms. Traffic (2008) 1.67
Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase. J Biol Chem (2002) 1.63
Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. J Biol Chem (2006) 1.61
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest (2013) 1.57
FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells. J Biol Chem (2009) 1.46
A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol. J Lipid Res (2011) 1.45
First synthesis of free cholesterol-BODIPY conjugates. J Org Chem (2006) 1.45
Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1. J Biol Chem (2003) 1.45
Membrane model for the G-protein-coupled receptor rhodopsin: hydrophobic interface and dynamical structure. Biophys J (2004) 1.41
Retinal counterion switch mechanism in vision evaluated by molecular simulations. J Am Chem Soc (2006) 1.40
The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors. J Pharmacol Exp Ther (2007) 1.40
The N-terminus of the intrinsically disordered protein α-synuclein triggers membrane binding and helix folding. Biophys J (2010) 1.39
FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells. J Biol Chem (2011) 1.37
A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems. Biophys J (2002) 1.35
Anisotropic motion and molecular dynamics of cholesterol, lanosterol, and ergosterol in lecithin bilayers studied by quasi-elastic neutron scattering. Biochemistry (2002) 1.34
Correlated fluorescence-atomic force microscopy of membrane domains: structure of fluorescence probes determines lipid localization. Biophys J (2005) 1.33
Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner. J Biol Chem (2009) 1.32
Y-chromosomal variation in sub-Saharan Africa: insights into the history of Niger-Congo groups. Mol Biol Evol (2010) 1.32
Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes. J Mol Biol (2007) 1.31
Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules. Cancer Res (2011) 1.28
Novel ceramide analogs as potential chemotherapeutic agents in breast cancer. J Pharmacol Exp Ther (2004) 1.28
Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma. J Biol Chem (2005) 1.27
Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate. J Cell Biochem (2010) 1.24
Rhodopsin reconstituted into a planar-supported lipid bilayer retains photoactivity after cross-linking polymerization of lipid monomers. J Am Chem Soc (2005) 1.24
(R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. Cell Signal (2011) 1.22
Docosahexaenoic acid enhances segregation of lipids between : 2H-NMR study. Biophys J (2008) 1.20
Adaptation of alphaviruses to heparan sulfate: interaction of Sindbis and Semliki forest viruses with liposomes containing lipid-conjugated heparin. J Virol (2002) 1.19
Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. J Org Chem (2009) 1.19
Binding of alpha-synuclein affects the lipid packing in bilayers of small vesicles. J Biol Chem (2006) 1.18
Structure of docosahexaenoic acid-containing phospholipid bilayers as studied by (2)H NMR and molecular dynamics simulations. J Am Chem Soc (2002) 1.17
Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. Biophys J (2004) 1.17
Inhibition of caveolar uptake, SV40 infection, and beta1-integrin signaling by a nonnatural glycosphingolipid stereoisomer. J Cell Biol (2007) 1.16
The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Cell Signal (2011) 1.15
Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies. Blood (2013) 1.14
Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation. Nat Struct Mol Biol (2011) 1.13
Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids. Chem Biol (2006) 1.13
Sterol effects and sites of sterol accumulation in Caenorhabditis elegans: developmental requirement for 4alpha-methyl sterols. J Lipid Res (2003) 1.12
Synthesis and evaluation of an alpha-C-galactosylceramide analogue that induces Th1-biased responses in human natural killer T cells. Chembiochem (2006) 1.11
Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells. Histochem Cell Biol (2008) 1.10
Deuterium NMR structure of retinal in the ground state of rhodopsin. Biochemistry (2004) 1.10
Electrostatic properties of membrane lipids coupled to metarhodopsin II formation in visual transduction. J Am Chem Soc (2002) 1.08
Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts). Biochim Biophys Acta (2007) 1.08
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. J Clin Invest (2014) 1.07
Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy. Biophys J (2005) 1.07
Solid-state 2H NMR structure of retinal in metarhodopsin I. J Am Chem Soc (2006) 1.07
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cell Signal (2010) 1.07
Lanosterol and cholesterol-induced variations in bilayer elasticity probed by 2H NMR relaxation. Langmuir (2004) 1.06
The 4,5-double bond of ceramide regulates its dipole potential, elastic properties, and packing behavior. Biophys J (2004) 1.06
Sphingolipid and cholesterol dependence of alphavirus membrane fusion. Lack of correlation with lipid raft formation in target liposomes. J Biol Chem (2002) 1.04
Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations. J Mol Biol (2007) 1.03
Role of ORPs in sterol transport from plasma membrane to ER and lipid droplets in mammalian cells. Traffic (2010) 1.03
Caveolar endocytosis and microdomain association of a glycosphingolipid analog is dependent on its sphingosine stereochemistry. J Biol Chem (2006) 1.03
Packing and viscoelasticity of polyunsaturated omega-3 and omega-6 lipid bilayers as seen by (2)H NMR and X-ray diffraction. J Am Chem Soc (2005) 1.03
Identification and characterization by electrospray mass spectrometry of endogenous Drosophila sphingadienes. J Lipid Res (2007) 1.02
NMR elastometry of fluid membranes in the mesoscopic regime. Phys Rev E Stat Nonlin Soft Matter Phys (2002) 1.02
Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. Am J Respir Cell Mol Biol (2013) 1.02
Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structures. Biochemistry (2014) 1.01
Flexibility of ras lipid modifications studied by 2H solid-state NMR and molecular dynamics simulations. Biophys J (2007) 1.01
Retracted Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid. Chem Biol (2012) 1.00
Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. J Biol Chem (2010) 1.00
The hedgehog receptor patched is involved in cholesterol transport. PLoS One (2011) 1.00
Lipid modifications of a Ras peptide exhibit altered packing and mobility versus host membrane as detected by 2H solid-state NMR. J Am Chem Soc (2005) 1.00
NKT TCR recognition of CD1d-α-C-galactosylceramide. J Immunol (2011) 0.99
Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate. J Am Chem Soc (2010) 0.99
Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. FASEB J (2011) 0.98
Fusion of alphaviruses with liposomes is a non-leaky process. FEBS Lett (2002) 0.98
Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin. Proc Natl Acad Sci U S A (2011) 0.97
Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. Anal Biochem (2010) 0.97
Elastic deformation of membrane bilayers probed by deuterium NMR relaxation. J Am Chem Soc (2002) 0.97
Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis. Cancer Res (2009) 0.96
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate. Biochem Biophys Res Commun (2009) 0.95
Synthesis of immunostimulatory alpha-C-galactosylceramide glycolipids via Sonogashira coupling, asymmetric epoxidation, and trichloroacetimidate-mediated epoxide opening. Org Lett (2010) 0.95
Interactions of very long-chain saturated fatty acids with serum albumin. J Lipid Res (2002) 0.95
Molecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes. J Am Chem Soc (2012) 0.95
Role of ceramide in membrane protein organization investigated by combined AFM and FCS. Biochim Biophys Acta (2008) 0.94
Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. Carcinogenesis (2012) 0.93
Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative. Biophys J (2009) 0.93
Ultra-high vacuum surface analysis study of rhodopsin incorporation into supported lipid bilayers. Langmuir (2008) 0.93
Synthesis of selective inhibitors of sphingosine kinase 1. Chem Commun (Camb) (2013) 0.93
Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells. J Biol Chem (2010) 0.92
Intrinsic cytotoxicity and chemomodulatory actions of novel phenethylisothiocyanate sphingoid base derivatives in HL-60 human promyelocytic leukemia cells. J Pharmacol Exp Ther (2004) 0.92
An NMR database for simulations of membrane dynamics. Biochim Biophys Acta (2010) 0.91