The MIF receptor CD74 in diabetic podocyte injury.

PubWeight™: 1.22‹?› | Rank: Top 10%

🔗 View Article (PMC 2637042)

Published in J Am Soc Nephrol on October 08, 2008

Authors

Maria Dolores Sanchez-Niño1, Ana Belen Sanz, Pekka Ihalmo, Markus Lassila, Harry Holthofer, Sergio Mezzano, Claudio Aros, Per-Henrik Groop, Moin A Saleem, Peter W Mathieson, Robert Langham, Matthias Kretzler, Viji Nair, Kevin V Lemley, Robert G Nelson, Eero Mervaala, Deborah Mattinzoli, Maria Pia Rastaldi, Marta Ruiz-Ortega, Jose Luis Martin-Ventura, Jesus Egido, Alberto Ortiz

Author Affiliations

1: Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain.

Articles citing this

Suppressors of cytokine signaling abrogate diabetic nephropathy. J Am Soc Nephrol (2010) 2.02

Molecular mechanisms of diabetic kidney disease. J Clin Invest (2014) 1.80

TNF superfamily: a growing saga of kidney injury modulators. Mediators Inflamm (2010) 1.20

Diabetic angiopathy, the complement system and the tumor necrosis factor superfamily. Nat Rev Endocrinol (2010) 1.12

TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α. Lab Invest (2011) 1.04

Elevated serum macrophage migration inhibitory factor (MIF) concentrations in chronic kidney disease (CKD) are associated with markers of oxidative stress and endothelial activation. Mol Med (2009) 0.98

Macrophage migration inhibitory factor: critical role in obesity, insulin resistance, and associated comorbidities. Mediators Inflamm (2010) 0.96

Fibrosis: a key feature of Fabry disease with potential therapeutic implications. Orphanet J Rare Dis (2013) 0.95

Inflammation in diabetic kidney disease. World J Diabetes (2014) 0.91

Is it or is it not a pathogenic mutation? Is it or is it not the podocyte? J Nephropathol (2012) 0.89

Macrophage migration inhibitory factor regulates interleukin-6 production by facilitating nuclear factor-kappa B activation during Vibrio vulnificus infection. BMC Immunol (2010) 0.88

Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. PLoS One (2013) 0.85

High glucose up-regulates angiotensin II subtype 2 receptors via interferon regulatory factor-1 in proximal tubule epithelial cells. Mol Cell Biochem (2010) 0.84

Receptor activator of NF-kappaB and podocytes: towards a function of a novel receptor-ligand pair in the survival response of podocyte injury. PLoS One (2012) 0.82

Increased urinary CD80 excretion and podocyturia in Fabry disease. J Transl Med (2016) 0.80

Urinary macrophage migration inhibitory factor serves as a potential biomarker for acute kidney injury in patients with acute pyelonephritis. Mediators Inflamm (2012) 0.80

The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice. PLoS One (2012) 0.80

TWEAK promotes peritoneal inflammation. PLoS One (2014) 0.79

Inhibition of macrophage migration inhibitory factor reduces diabetic nephropathy in type II diabetes mice. Inflammation (2014) 0.79

Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factor. J Cell Mol Med (2015) 0.79

Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging. BMC Genomics (2013) 0.79

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications. Oncotarget (2017) 0.77

Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury. Sci Rep (2016) 0.77

Chemokine profile in the sera and urine of patients with schistosomal glomerulopathy. Am J Trop Med Hyg (2013) 0.76

Macrophage Migration Inhibitory Factor in Clinical Kidney Disease. Front Immunol (2016) 0.76

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74. J Am Soc Nephrol (2015) 0.76

Macrophage Migration Inhibitory Factor: A Novel Inhibitor of Apoptosis Signal-Regulating Kinase 1-p38-Xanthine Oxidoreductase-Dependent Cigarette Smoke-Induced Apoptosis. Am J Respir Cell Mol Biol (2016) 0.75

Cinnabar-induced subchronic renal injury is associated with increased apoptosis in rats. Biomed Res Int (2015) 0.75

Fabry disease: the many faces of a single disorder. Clin Kidney J (2012) 0.75

CD74 in Kidney Disease. Front Immunol (2015) 0.75

Articles cited by this

Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci U S A (1966) 12.29

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev (2004) 9.54

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol (2002) 6.48

MIF signal transduction initiated by binding to CD74. J Exp Med (2003) 4.79

Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest (2001) 3.40

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy. Diabetes (2006) 2.85

Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci (1997) 2.80

MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis. Nat Rev Drug Discov (2006) 2.30

Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injury. Kidney Int (2004) 2.29

MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy. Am J Physiol Renal Physiol (2008) 2.00

Surface antigens of melanoma and melanocytes. Specificity of induction of Ia antigens by human gamma-interferon. J Exp Med (1984) 1.81

Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes (2007) 1.55

Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J Am Soc Nephrol (2005) 1.47

The cytokine TWEAK modulates renal tubulointerstitial inflammation. J Am Soc Nephrol (2008) 1.43

CD74 is a member of the regulated intramembrane proteolysis-processed protein family. Mol Biol Cell (2005) 1.42

The role of TNF-alpha in diabetic nephropathy: pathogenic and therapeutic implications. Cytokine Growth Factor Rev (2006) 1.38

Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys. J Investig Med (1997) 1.26

The death ligand TRAIL in diabetic nephropathy. J Am Soc Nephrol (2008) 1.25

Inflammation and diabetic nephropathy. Curr Diab Rep (2006) 1.23

Expression of macrophage migration inhibitory factor in human glomerulonephritis. Kidney Int (2000) 1.20

Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy. Am J Kidney Dis (2005) 1.19

p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. Prog Med Chem (2001) 1.16

Association of systemic concentrations of macrophage migration inhibitory factor with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg, Survey 4 (KORA S4). Diabetes Care (2006) 1.15

Insight into the biology of macrophage migration inhibitory factor (MIF) revealed by the cloning of its cell surface receptor. Cell Res (2006) 1.14

Proapoptotic Fas ligand is expressed by normal kidney tubular epithelium and injured glomeruli. J Am Soc Nephrol (2000) 1.12

Aqueous levels of macrophage migration inhibitory factor and monocyte chemotactic protein-1 in patients with diabetic retinopathy. Diabet Med (2004) 1.01

Expression of Smac/Diablo in tubular epithelial cells and during acute renal failure. Kidney Int Suppl (2003) 0.98

Transgene of MIF induces podocyte injury and progressive mesangial sclerosis in the mouse kidney. Kidney Int (2004) 0.97

Urine macrophage migration inhibitory factor reflects the severity of renal injury in human glomerulonephritis. J Am Soc Nephrol (2002) 0.97

Induction of MIF synthesis and secretion by tubular epithelial cells: a novel action of angiotensin II. Kidney Int (2003) 0.96

Mechanism of UV-induced apoptosis in human leukemia cells: roles of Ca2+/Mg(2+)-dependent endonuclease, caspase-3, and stress-activated protein kinases. Exp Cell Res (1998) 0.81

Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells. Nephrology (Carlton) (2003) 0.80

Molecular cloning and characterization of an endogenous antisense transcript of Nphs1. Genomics (2004) 0.78

Articles by these authors

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95

The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43

The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int (2009) 7.45

The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Kidney Int (2009) 7.19

Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial. Lancet (2013) 7.03

Cell biology of the glomerular podocyte. Physiol Rev (2003) 6.85

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol (2002) 6.48

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. N Engl J Med (2011) 6.34

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Evaluation of the modification of diet in renal disease study equation in a large diverse population. J Am Soc Nephrol (2007) 6.00

Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int (2011) 5.47

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet (2012) 5.10

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest (2007) 4.80

Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest (2004) 4.65

Modification of kidney barrier function by the urokinase receptor. Nat Med (2007) 4.01

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol (2011) 3.83

Mouse models of diabetic nephropathy. J Am Soc Nephrol (2009) 3.74

Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study. J Am Soc Nephrol (2005) 3.48

Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19

National Kidney Foundation's Kidney Disease Outcomes Quality Initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification. Pediatrics (2003) 3.10

Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab (2010) 3.05

Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05

Incidence of end-stage renal disease in patients with type 1 diabetes. JAMA (2005) 3.01

Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy. Kidney Int (2012) 2.97

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest (2011) 2.90

Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies. Kidney Int (2003) 2.90

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy. Diabetes (2006) 2.85

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest (2011) 2.72

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat Med (2006) 2.65

Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism. Circulation (2005) 2.55

Urinary excretion of viable podocytes in health and renal disease. Am J Physiol Renal Physiol (2003) 2.55

Females with Fabry disease frequently have major organ involvement: lessons from the Fabry Registry. Mol Genet Metab (2007) 2.51

Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50

The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility. J Immunol (2011) 2.44

Proteinuria and hyperglycemia induce endoplasmic reticulum stress. J Am Soc Nephrol (2008) 2.41

Sodium intake and hypertension. Prog Cardiovasc Dis (2006) 2.39

Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application. Kidney Int (2002) 2.34

Cilastatin protects against cisplatin-induced nephrotoxicity without compromising its anticancer efficiency in rats. Kidney Int (2012) 2.34

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. Blood (2009) 2.33

Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol (2006) 2.32

Metabolic syndrome in type 1 diabetes: association with diabetic nephropathy and glycemic control (the FinnDiane study). Diabetes Care (2005) 2.26

Inflammation and angiotensin II. Int J Biochem Cell Biol (2003) 2.22

Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy. J Am Soc Nephrol (2012) 2.21

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy. J Am Soc Nephrol (2007) 2.20

Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation. Diabetes Care (2011) 2.20

The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes. Diabetes Care (2011) 2.16

Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res (2008) 2.15

The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. Kidney Int (2010) 2.14

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2013) 2.10

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. J Cell Sci (2008) 2.09

Prorenin receptor is essential for normal podocyte structure and function. J Am Soc Nephrol (2011) 2.08

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy. Diabetes (2008) 2.07

Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians. JAMA (2006) 2.07

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell (2011) 2.06

Leisure-time physical activity and development and progression of diabetic nephropathy in type 1 diabetes: the FinnDiane Study. Diabetologia (2015) 2.05

Suppressors of cytokine signaling abrogate diabetic nephropathy. J Am Soc Nephrol (2010) 2.02

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. J Clin Invest (2007) 2.02

Lanthanum carbonate reduces FGF23 in chronic kidney disease Stage 3 patients. Nephrol Dial Transplant (2011) 2.02

Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes. Am J Physiol Renal Physiol (2003) 2.00

NF-kappaB in renal inflammation. J Am Soc Nephrol (2010) 2.00

Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue. Am J Pathol (2002) 1.96

Defining cell-type specificity at the transcriptional level in human disease. Genome Res (2013) 1.96

Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy. J Am Soc Nephrol (2013) 1.94

Tenofovir nephrotoxicity: 2011 update. AIDS Res Treat (2011) 1.94

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest (2013) 1.92

Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes. Diabetes Care (2007) 1.92

Periadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet-induced obese C57Bl/6 mice. Circ J (2010) 1.91

Nephrin mutations cause childhood- and adult-onset focal segmental glomerulosclerosis. Kidney Int (2009) 1.88

The podocyte cytoskeleton--key to a functioning glomerulus in health and disease. Nat Rev Nephrol (2011) 1.86

Early glomerular filtration defect and severe renal disease in podocin-deficient mice. Mol Cell Biol (2004) 1.85

Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. J Immunol (2011) 1.85

Competing-risk analysis of ESRD and death among patients with type 1 diabetes and macroalbuminuria. J Am Soc Nephrol (2011) 1.82

Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities. Kidney Int (2010) 1.81

Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J Am Soc Nephrol (2008) 1.81

Gene expression in the normal adult human kidney assessed by complementary DNA microarray. Mol Biol Cell (2003) 1.79

Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79

New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet (2012) 1.79

NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy. Nephrol Dial Transplant (2004) 1.78