Published in Biopolymers on January 01, 2008
Design and NMR characterization of active analogues of compstatin containing non-natural amino acids. J Med Chem (2005) 1.28
Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity. J Am Chem Soc (2003) 1.28
Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. J Mol Biol (2003) 1.20
Synthetic small-molecule complement inhibitors. Curr Opin Investig Drugs (2004) 1.20
Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. J Immunol (2005) 1.15
Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Mol Immunol (2003) 1.12
Implicit solvent simulations of DPC micelle formation. J Phys Chem B (2005) 1.09
A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization. Plant Cell (2009) 1.07
Studies of structure-activity relations of complement inhibitor compstatin. J Immunol (2003) 1.04
De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation. J Med Chem (2012) 1.04
Toward full-sequence de novo protein design with flexible templates for human beta-defensin-2. Biophys J (2007) 1.03
An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data. Biopolymers (2011) 0.99
Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization. Ann Biomed Eng (2010) 0.97
Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues. J Am Chem Soc (2005) 0.97
A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. J Exp Bot (2010) 0.96
Automated computational framework for the analysis of electrostatic similarities of proteins. Biotechnol Prog (2011) 0.95
Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations. Proteins (2010) 0.95
Conformational interconversion in compstatin probed with molecular dynamics simulations. Proteins (2003) 0.94
Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics. Biophys J (2006) 0.94
Complement: structure, functions, evolution, and viral molecular mimicry. Immunol Res (2003) 0.93
Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity. J Biol Chem (2007) 0.92
Immunophysical exploration of C3d-CR2(CCP1-2) interaction using molecular dynamics and electrostatics. J Mol Biol (2007) 0.92
A new generation of potent complement inhibitors of the Compstatin family. Chem Biol Drug Des (2011) 0.91
Molecular dynamics in drug design: new generations of compstatin analogs. Chem Biol Drug Des (2012) 0.90
Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin. J Biol Chem (2004) 0.89
Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water. J Mol Graph Model (2007) 0.88
Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin. Proteins (2011) 0.88
The effect of electrostatics on factor H function and related pathologies. J Mol Graph Model (2011) 0.88
The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity. PLoS Comput Biol (2012) 0.86
Proteomic profiling of aging in the mouse heart: Altered expression of mitochondrial proteins. Arch Biochem Biophys (2008) 0.85
Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties. BMC Biophys (2012) 0.85
Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data. Biopolymers (2010) 0.84
Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures. Exp Eye Res (2013) 0.83
Contribution of specific amino acid changes in penicillin binding protein 1 to amoxicillin resistance in clinical Helicobacter pylori isolates. Antimicrob Agents Chemother (2010) 0.83
Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus. J Immunol (2010) 0.82
Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops. PLoS One (2012) 0.79
Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex. Protein Sci (2015) 0.79
pH dependence of stability of the 10th human fibronectin type III domain: a computational study. Biotechnol Prog (2007) 0.79
Engineering pre-SUMO4 as efficient substrate of SENP2. Protein Eng Des Sel (2014) 0.78
Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics. Biopolymers (2008) 0.78
Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan. Mol Immunol (2011) 0.78
NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides. Biopolymers (2009) 0.77
A predictive model for HIV type 1 coreceptor selectivity. AIDS Res Hum Retroviruses (2013) 0.77
Solution structure of a bent alpha-helix. Biochemistry (2007) 0.77
New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics. J Med Chem (2014) 0.76
Proteomics and systems biology: application in drug discovery and development. Methods Mol Biol (2010) 0.76
Comparison of SYPRO Ruby and Flamingo fluorescent stains for application in proteomic research. Anal Biochem (2009) 0.75