Published in Biopolymers on January 01, 2009
Molecular diagnostic tools in mycobacteriology. J Microbiol Methods (2008) 1.66
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). Br J Pharmacol (2013) 1.56
Design and NMR characterization of active analogues of compstatin containing non-natural amino acids. J Med Chem (2005) 1.28
Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity. J Am Chem Soc (2003) 1.28
Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. J Mol Biol (2003) 1.20
Synthetic small-molecule complement inhibitors. Curr Opin Investig Drugs (2004) 1.20
Mechanism of Cu(A) assembly. Nat Chem Biol (2008) 1.17
IL-1 cytokines in cardiovascular disease: diagnostic, prognostic and therapeutic implications. Cardiovasc Hematol Agents Med Chem (2008) 1.16
Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. J Immunol (2005) 1.15
Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Mol Immunol (2003) 1.12
A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization. Plant Cell (2009) 1.07
Studies of structure-activity relations of complement inhibitor compstatin. J Immunol (2003) 1.04
De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation. J Med Chem (2012) 1.04
Toward full-sequence de novo protein design with flexible templates for human beta-defensin-2. Biophys J (2007) 1.03
An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data. Biopolymers (2011) 0.99
The delivery of copper for thylakoid import observed by NMR. Proc Natl Acad Sci U S A (2006) 0.98
Development of a quasi-dynamic pharmacophore model for anti-complement peptide analogues. J Am Chem Soc (2005) 0.97
Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization. Ann Biomed Eng (2010) 0.97
K-ras mutation, HPV infection and smoking or alcohol abuse positively correlate with esophageal squamous carcinoma. Pathol Oncol Res (2008) 0.97
A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. J Exp Bot (2010) 0.96
Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations. Proteins (2010) 0.95
Automated computational framework for the analysis of electrostatic similarities of proteins. Biotechnol Prog (2011) 0.95
NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes. J Biol Chem (2008) 0.94
Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics. Biophys J (2006) 0.94
Conformational interconversion in compstatin probed with molecular dynamics simulations. Proteins (2003) 0.94
CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thromb Res (2007) 0.94
NOD2 insertion mutation in a Cretan Crohn's disease population. Gastroenterology (2003) 0.93
Complement: structure, functions, evolution, and viral molecular mimicry. Immunol Res (2003) 0.93
Immunophysical exploration of C3d-CR2(CCP1-2) interaction using molecular dynamics and electrostatics. J Mol Biol (2007) 0.92
Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity. J Biol Chem (2007) 0.92
A new generation of potent complement inhibitors of the Compstatin family. Chem Biol Drug Des (2011) 0.91
Molecular dynamics in drug design: new generations of compstatin analogs. Chem Biol Drug Des (2012) 0.90
RING finger E(3) ubiquitin ligases: structure and drug discovery. Curr Pharm Des (2009) 0.89
Mycobacterial species diversity at a general hospital on the island of Crete: first detection of Mycobacterium lentiflavum in Greece. Scand J Infect Dis (2007) 0.89
Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin. J Biol Chem (2004) 0.89
RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis. Pediatr Infect Dis J (2008) 0.89
Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water. J Mol Graph Model (2007) 0.88
Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin. Proteins (2011) 0.88
The effect of electrostatics on factor H function and related pathologies. J Mol Graph Model (2011) 0.88
Chemokines in vascular pathology (review). Int J Mol Med (2006) 0.86
The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity. PLoS Comput Biol (2012) 0.86
Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties. BMC Biophys (2012) 0.85
Conformational properties of HIV-1 gp120/V3 immunogenic domains. Curr Med Chem (2005) 0.85
A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells. Toxicol Lett (2006) 0.85
Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: implications of the interaction with chemokine receptor CCR5. Int J Mol Med (2007) 0.85
Structure-function discrimination of the N- and C- catalytic domains of human angiotensin-converting enzyme: implications for Cl- activation and peptide hydrolysis mechanisms. Protein Eng (2003) 0.84
Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data. Biopolymers (2010) 0.84
Simulated interactions between angiotensin-converting enzyme and substrate gonadotropin-releasing hormone: novel insights into domain selectivity. Biochemistry (2007) 0.83
Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures. Exp Eye Res (2013) 0.83
Enzymatic stability, solution structure, and antiproliferative effect on prostate cancer cells of leuprolide and new gonadotropin-releasing hormone peptide analogs. Biopolymers (2011) 0.83
Low molecular weight inhibitors of the protease anthrax lethal factor. Mini Rev Med Chem (2008) 0.83
Three isoforms of complement properdin factor P in trout: cloning, expression, gene organization and constrained modeling. Dev Comp Immunol (2008) 0.83
Contribution of specific amino acid changes in penicillin binding protein 1 to amoxicillin resistance in clinical Helicobacter pylori isolates. Antimicrob Agents Chemother (2010) 0.83
Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus. J Immunol (2010) 0.82
HIV-1 gp120/V3-derived epitopes promote activation-induced cell death to superantigen-stimulated CD4+/CD45RO+ T cells. Immunol Lett (2006) 0.82
CCR2-64I and CXCL12 3'A alleles confer a favorable prognosis to AIDS patients undergoing HAART therapy. J Clin Virol (2005) 0.81
Miliary tuberculosis with no pulmonary involvement in myelodysplastic syndromes: a curable, yet rarely diagnosed, disease: case report and review of the literature. Ann Clin Microbiol Antimicrob (2008) 0.81
Peripheral monocytes from diabetic patients with coronary artery disease display increased bFGF and VEGF mRNA expression. J Transl Med (2003) 0.81
Mapping protein-protein interaction by 13C'-detected heteronuclear NMR spectroscopy. J Biomol NMR (2006) 0.81
The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature. J Transl Med (2011) 0.80
Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular inflammation and atherogenesis. J Thromb Thrombolysis (2010) 0.80
Ionic interaction of the HIV-1 V3 domain with CCR5 and deregulation of T lymphocyte function. Biochem Biophys Res Commun (2002) 0.79
pH dependence of stability of the 10th human fibronectin type III domain: a computational study. Biotechnol Prog (2007) 0.79
Activation-induced cell death signalling in CD4+ T cells by staphylococcal enterotoxin A. Toxicol Lett (2007) 0.79
Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex. Protein Sci (2015) 0.79
Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops. PLoS One (2012) 0.79
Solid-phase synthesis and conformational properties of angiotensin converting enzyme catalytic-site peptides: the basis for a structural study on the enzyme-substrate interaction. Biopolymers (2004) 0.79
A computational approach to the study of the binding mode of dual ACE/NEP inhibitors. J Chem Inf Model (2010) 0.79
The stability of the cytochrome c scaffold as revealed by NMR spectroscopy. J Inorg Biochem (2004) 0.78
Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics. Biopolymers (2008) 0.78
Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan. Mol Immunol (2011) 0.78
Study of the interaction between the amyloid beta peptide (1-40) and antioxidant compounds by nuclear magnetic resonance spectroscopy. Biopolymers (2011) 0.78
Light scattering characterization of synthetic MUC-1 peptides and their behavior in dilute solution. Int J Mol Med (2003) 0.78
Conformational dynamics of the anthrax lethal factor catalytic center. Biochemistry (2010) 0.78
A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro. J Cell Biochem (2011) 0.78
Engineering pre-SUMO4 as efficient substrate of SENP2. Protein Eng Des Sel (2014) 0.78
In vitro inhibition of R5 HIV-1 infectivity by X4 V3-derived synthetic peptides. Int J Mol Med (2005) 0.78
A predictive model for HIV type 1 coreceptor selectivity. AIDS Res Hum Retroviruses (2013) 0.77
Biophysical characterization of V3-lipopeptide liposomes influencing HIV-1 infectivity. Biochem Biophys Res Commun (2007) 0.77
Solution structure of a bent alpha-helix. Biochemistry (2007) 0.77
Backbone and side chain NMR assignment, along with the secondary structure prediction of RRM2 domain of La protein from a lower eukaryote exhibiting identical structural organization with its human homolog. Biomol NMR Assign (2014) 0.77
Zinc binding in peptide models of angiotensin-I converting enzyme active sites studied through 1H-NMR and chemical shift perturbation mapping. Biopolymers (2003) 0.77
Study of a lipophilic captopril analogue binding to angiotensin I converting enzyme. J Pept Sci (2010) 0.77
High yield expression and NMR characterization of Arkadia E3 ubiquitin ligase RING-H2 finger domain. Biochem Biophys Res Commun (2008) 0.77
Unravelling the conformational plasticity of the extracellular domain of a prokaryotic nAChR homologue in solution by NMR. Biochemistry (2011) 0.77
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. Int J Gastrointest Cancer (2002) 0.77
Putative bioactive conformations of amide linked cyclic myelin basic protein peptide analogues associated with experimental autoimmune encephalomyelitis. J Med Chem (2007) 0.76
Molecular size determination of a membrane protein in surfactants by light scattering. Biochim Biophys Acta (2003) 0.76
NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase. Proteins (2012) 0.76
A 40.7 kDa Rpp30/Rpp1 homologue is a protein subunit of Dictyostelium discoideum RNase P holoenzyme. Biochimie (2006) 0.76
Structural study of Ac-Phe-[Orn-Pro-dCha-Trp-Arg], a potent C5a receptor antagonist, by NMR. Biopolymers (2008) 0.76
New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics. J Med Chem (2014) 0.76
A comparative approach towards thylakoid membrane proteome analysis of unicellular green alga Scenedesmus obliquus. Biochim Biophys Acta (2007) 0.76
¹H, ¹⁵N, ¹³C assignment and secondary structure determination of two domains of La protein from D. discoideum. Biomol NMR Assign (2012) 0.75