Published in Proc Natl Acad Sci U S A on October 14, 2008
Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications. Curr Opin Chem Biol (2010) 1.61
Enantioselective synthesis of tryptophan derivatives by a tandem Friedel-Crafts conjugate addition/asymmetric protonation reaction. J Am Chem Soc (2012) 0.96
Exploring the substrate range of wild-type aminoacyl-tRNA synthetases. Chembiochem (2014) 0.86
Importance of single molecular determinants in the fidelity of expanded genetic codes. Proc Natl Acad Sci U S A (2011) 0.81
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration. Beilstein J Org Chem (2014) 0.80
Multivalent protein polymers with controlled chemical and physical properties. Adv Drug Deliv Rev (2010) 0.80
Fluorescence anisotropy and resonance energy transfer: powerful tools for measuring real time protein dynamics in a physiological environment. Curr Opin Pharmacol (2010) 0.79
N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3. FEBS J (2015) 0.78
Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties. Org Lett (2014) 0.76
Tryptophan-based fluorophores for studying protein conformational changes. Bioorg Med Chem (2014) 0.75
Specific covalent labeling of recombinant protein molecules inside live cells. Science (1998) 9.32
Annexins: from structure to function. Physiol Rev (2002) 6.78
The effect of amino acid analogues on growth and protein synthesis in microorganisms. Bacteriol Rev (1962) 3.89
High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli. Eur J Biochem (1995) 2.44
The crystal and molecular structure of human annexin V, an anticoagulant protein that binds to calcium and membranes. EMBO J (1990) 2.19
New caged coumarin fluorophores with extraordinary uncaging cross sections suitable for biological imaging applications. J Am Chem Soc (2004) 1.74
Prolegomena to future experimental efforts on genetic code engineering by expanding its amino acid repertoire. Angew Chem Int Ed Engl (2004) 1.39
Incorporation of azatryptophan into proteins of bacteria and bacteriophage. Biochim Biophys Acta (1956) 1.39
Expansion of the genetic code enables design of a novel "gold" class of green fluorescent proteins. J Mol Biol (2003) 1.34
Enhancement of protein spectra with tryptophan analogs: fluorescence spectroscopy of protein-protein and protein-nucleic acid interactions. Methods Enzymol (1997) 1.30
Genetic and kinetic evidence for different types of postreplication repair in Escherichia coli B. J Bacteriol (1975) 1.27
Atomic mutations at the single tryptophan residue of human recombinant annexin V: effects on structure, stability, and activity. Biochemistry (1999) 1.05
A rapid and efficient purification method for recombinant annexin V for biophysical studies. FEBS Lett (1993) 1.01
Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code. Biol Chem (2004) 0.95
Fluorescent amino acid analogs. Methods Enzymol (2003) 0.94
Designing novel spectral classes of proteins with a tryptophan-expanded genetic code. Biol Chem (2004) 0.90
Biosynthetic incorporation of 7-azatryptophan into the phage lambda lysozyme: estimation of tryptophan accessibility, effect on enzymatic activity and protein stability. Protein Eng (1995) 0.90
Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors. Angew Chem Int Ed Engl (2002) 0.88
Lactococcus lactis as expression host for the biosynthetic incorporation of tryptophan analogues into recombinant proteins. Biochem J (2008) 0.85
Efficient biosynthetic incorporation of tryptophan and indole analogs in an integral membrane protein. Protein Sci (2003) 0.85
Aminotryptophan-containing barstar: structure--function tradeoff in protein design and engineering with an expanded genetic code. Biochim Biophys Acta (2006) 0.85
PCR mutagenesis and overexpression of tryptophan synthase from Salmonella typhimurium: on the roles of beta2 subunit Lys-382. Protein Expr Purif (1996) 0.85
An evaluation of the Escherichia coli WP2 and WP2 uvrA reverse mutation assay. Mutat Res (1980) 0.81
In vivo engineering of proteins with nitrogen-containing tryptophan analogs. Appl Microbiol Biotechnol (2006) 0.80
Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base. Spectrochim Acta A Mol Biomol Spectrosc (2002) 0.80
Excited state tautomerization of azaindole. Org Biomol Chem (2005) 0.78
Expansion of the genetic code enables design of a novel "gold" class of green fluorescent proteins. J Mol Biol (2003) 1.34
Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein. Proc Natl Acad Sci U S A (2009) 1.10
Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline. PLoS One (2008) 1.07
Slow exchange in the chromophore of a green fluorescent protein variant. J Am Chem Soc (2002) 1.02
Recent advances in genetic code engineering in Escherichia coli. Curr Opin Biotechnol (2012) 1.01
Performance analysis of orthogonal pairs designed for an expanded eukaryotic genetic code. PLoS One (2012) 0.95
Congeneric lantibiotics from ribosomal in vivo peptide synthesis with noncanonical amino acids. Angew Chem Int Ed Engl (2011) 0.93
In vivo incorporation of multiple noncanonical amino acids into proteins. Angew Chem Int Ed Engl (2011) 0.92
Fine tuning the N-terminal residue excision with methionine analogues. Chembiochem (2009) 0.91
Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds. Chem Commun (Camb) (2011) 0.87
Blue fluorescent amino acids as in vivo building blocks for proteins. Chembiochem (2010) 0.87
Sense codon emancipation for proteome-wide incorporation of noncanonical amino acids: rare isoleucine codon AUA as a target for genetic code expansion. FEMS Microbiol Lett (2014) 0.85
Site-directed and global incorporation of orthogonal and isostructural noncanonical amino acids into the ribosomal lasso peptide capistruin. Chembiochem (2014) 0.85
Aminotryptophan-containing barstar: structure--function tradeoff in protein design and engineering with an expanded genetic code. Biochim Biophys Acta (2006) 0.85
Peptidyl prolyl cis/trans-isomerases: comparative reactivities of cyclophilins, FK506-binding proteins, and parvulins with fluorinated oligopeptide and protein substrates. Biochemistry (2005) 0.85
Covalent attachment of cyclic TAT peptides to GFP results in protein delivery into live cells with immediate bioavailability. Angew Chem Int Ed Engl (2014) 0.85
Expanding the genetic code of Saccharomyces cerevisiae with methionine analogues. Yeast (2008) 0.84
In vivo double and triple labeling of proteins using synthetic amino acids. Angew Chem Int Ed Engl (2010) 0.84
Conjugation of proteins by installing BIO-orthogonally reactive groups at their N-termini. PLoS One (2012) 0.83
Structural and spectral response of Aequorea victoria green fluorescent proteins to chromophore fluorination. Biochemistry (2005) 0.83
Engineering protein sequence composition for folding robustness renders efficient noncanonical amino acid incorporations. Chembiochem (2010) 0.82
Intracellular uptake and inhibitory activity of aromatic fluorinated amino acids in human breast cancer cells. ChemMedChem (2008) 0.82
On the road towards chemically modified organisms endowed with a genetic firewall. Angew Chem Int Ed Engl (2011) 0.82
Crystallographic evidence for isomeric chromophores in 3-fluorotyrosyl-green fluorescent protein. Chembiochem (2004) 0.81
Natural history and experimental evolution of the genetic code. Appl Microbiol Biotechnol (2007) 0.81
In vivo chemoenzymatic control of N-terminal processing in recombinant human epidermal growth factor. Chembiochem (2007) 0.80
Directed manipulation of a flavoprotein photocycle. Angew Chem Int Ed Engl (2013) 0.80
In vivo engineering of proteins with nitrogen-containing tryptophan analogs. Appl Microbiol Biotechnol (2006) 0.80
Synthetic biology of protein folding. Chemphyschem (2010) 0.80
Efficient N-terminal glycoconjugation of proteins by the N-end rule. Chembiochem (2008) 0.80
Parallel incorporation of different fluorinated amino acids: on the way to "teflon" proteins. Chembiochem (2010) 0.79
Gold fluorescent annexin A5 as a novel apoptosis detection tool. Cytometry A (2009) 0.79
Enhancing the thermal stability of a single-chain Fv fragment by in vivo global fluorination of the proline residues. Mol Biosyst (2010) 0.79
Improved method to retain cytosolic reporter protein fluorescence while staining for nuclear proteins. Cytometry A (2014) 0.78
Bioconjugation of L-3,4-dihydroxyphenylalanine containing protein with a polysaccharide. Bioconjug Chem (2011) 0.78
Protein iodination by click chemistry. Chembiochem (2009) 0.77
Expanding and engineering the genetic code in a single expression experiment. Chembiochem (2011) 0.77
Genetically encoded photocrosslinkers as molecular probes to study G-protein-coupled receptors (GPCRs). Angew Chem Int Ed Engl (2011) 0.76
Convenient syntheses of homopropargylglycine. J Pept Sci (2008) 0.76
Docking of tryptophanyl [corrected tryptophan] analogs to trytophanyl-tRNA synthetase: implications for non-canonical amino acid incorporations. Biol Chem (2008) 0.76
Evaluation of bicinchoninic acid as a ligand for copper(I)-catalyzed azide-alkyne bioconjugations. Org Biomol Chem (2012) 0.76
Congeneric bio-adhesive mussel foot proteins designed by modified prolines revealed a chiral bias in unnatural translation. Biochem Biophys Res Commun (2012) 0.75
Electrospray ionization mass spectrometric studies of nucleophilic carbenes derived from pyrazolium and indazolium carboxylates. Rapid Commun Mass Spectrom (2005) 0.75
Site-specific conjugation of 8-ethynyl-BODIPY to a protein by [2 + 3] cycloaddition. Org Biomol Chem (2015) 0.75
Amide rotation trajectories probed by symmetry. Org Biomol Chem (2017) 0.75
Design of protein congeners containing β-cyclopropylalanine. Mol Biosyst (2012) 0.75
Orthogonal translation meets electron transfer: in vivo labeling of cytochrome c for probing local electric fields. Chembiochem (2015) 0.75
A peptidyl-prolyl model study: How does the electronic effect influence the amide bond conformation? J Org Chem (2017) 0.75
Azatryptophans as tools to study polarity requirements for folding of green fluorescent protein. J Pept Sci (2010) 0.75
Applying γ-substituted prolines in the foldon peptide: polarity contradicts preorganization. Chembiochem (2014) 0.75