D Lamarre

Author PubWeight™ 31.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors. J Virol 1996 3.39
2 Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors. J Virol 1997 3.29
3 Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell 1991 1.53
4 The effect of poly(ADP-ribosyl)ation on native and H1-depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure. J Biol Chem 1989 1.46
5 Modulation of chromatin superstructure induced by poly(ADP-ribose) synthesis and degradation. J Biol Chem 1986 1.30
6 Persistence and determinants of statin therapy among middle-aged patients for primary and secondary prevention. Br J Clin Pharmacol 2005 1.29
7 In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus. J Biol Chem 2001 1.17
8 Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere. Structure 1995 1.10
9 Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors. J Virol 1998 1.07
10 Peptide-based inhibitors of the hepatitis C virus serine protease. Bioorg Med Chem Lett 1998 1.03
11 Determination of kinetic rate constants for the binding of inhibitors to HIV-1 protease and for the association and dissociation of active homodimer. Biochemistry 1994 1.00
12 Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors. Bioorg Med Chem Lett 2000 0.96
13 The role of the pharmacist in humanitarian aid in Bosnia-Herzegovina: the experience of Pharmaciens Sans Frontières. Ann Pharmacother 2000 0.93
14 Immunoelectron microscopical distribution of poly(ADP-ribose)polymerase in the mammalian cell nucleus. Exp Cell Res 1988 0.89
15 Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease. Bioorg Med Chem Lett 1998 0.87
16 Production and characterization of monoclonal antibodies specific for the functional domains of poly(ADP-ribose) polymerase. Biochem Cell Biol 1986 0.87
17 Possible role of ADP-ribosylation of adenovirus core proteins in virus infection. Virus Res 1986 0.86
18 Visualization of poly(ADP-ribose) synthetase associated with polynucleosomes by immunoelectron microscopy. Biochim Biophys Acta 1986 0.86
19 Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain. J Biol Chem 1999 0.85
20 Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. Proc Natl Acad Sci U S A 1993 0.85
21 A positive signal is transduced via surface CD4 molecules. Res Immunol 1989 0.83
22 Microtube batch protein crystallization: applications to human immunodeficiency virus type 2 (HIV-2) protease and human renin. Proteins 1994 0.82
23 High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors. J Mol Biol 1995 0.80
24 NMR line-broadening and transferred NOESY as a medicinal chemistry tool for studying inhibitors of the hepatitis C virus NS3 protease domain. Bioorg Med Chem Lett 2000 0.80
25 Enzymatic characterization of purified recombinant human renin. Biochem Cell Biol 1995 0.79
26 Potent HIV protease inhibitors containing a novel (hydroxyethyl)amide isostere. J Med Chem 1997 0.78
27 2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors. J Med Chem 2000 0.78
28 Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. J Biol Chem 1995 0.76
29 Quantification of cytosolic steroid receptors in secretory and non-secretory epithelial cells of the canine prostate. J Steroid Biochem 1985 0.75
30 Time-resolved ligand exchange reactions: kinetic models for competitive inhibitors with recombinant human renin. J Med Chem 1995 0.75
31 Kinetic analysis of attached growth nitrification in cold climates. Water Sci Technol 2009 0.75
32 The human renin infused rat: use as an in vivo model for the biological evaluation of human renin inhibitors. Can J Physiol Pharmacol 1999 0.75