Published in Neoplasia on November 01, 2008
HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. J Biol Chem (2010) 1.24
Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms. Oncogene (2012) 1.14
Production of Monoclonal Antibody against Human Nestin. Avicenna J Med Biotechnol (2010) 1.06
MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer. Expert Rev Mol Diagn (2009) 1.02
An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch. Cancer Lett (2012) 0.89
Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis. Neoplasia (2011) 0.86
Altered expression of p120catenin predicts poor outcome in invasive breast cancer. J Cancer Res Clin Oncol (2010) 0.85
Genetically engineered mice as experimental tools to dissect the critical events in breast cancer. Adv Cancer Res (2014) 0.84
A novel role of EMMPRIN/CD147 in transformation of quiescent fibroblasts to cancer-associated fibroblasts by breast cancer cells. Cancer Lett (2013) 0.84
Assembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes. Biochemistry (2013) 0.83
Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints. J Cell Sci (2013) 0.82
Single and Multiple Gene Manipulations in Mouse Models of Human Cancer. Cancer Growth Metastasis (2015) 0.80
Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. Am J Transl Res (2015) 0.80
Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development. Cancer Lett (2012) 0.80
Altered localization of p120 catenin in the cytoplasm rather than the membrane correlates with poor prognosis in esophageal squamous cell carcinoma. PLoS One (2015) 0.79
Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype. Sci Rep (2017) 0.77
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer. PLoS One (2015) 0.75
Signaling mechanisms that suppress the cytostatic actions of rapamycin. PLoS One (2014) 0.75
The War on Cancer rages on. Neoplasia (2009) 0.75
Cyclin-Dependent Kinase Inhibitors as Anticancer Therapeutics. Mol Pharmacol (2015) 0.75
Neoplasia: the second decade. Neoplasia (2008) 0.75
Dinosaurs and ancient civilizations: reflections on the treatment of cancer. Neoplasia (2010) 0.75
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A (2001) 71.82
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell (2006) 27.36
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA (2006) 24.01
Molecular definition of breast tumor heterogeneity. Cancer Cell (2007) 12.67
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci U S A (1986) 12.14
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res (2008) 6.95
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol (2006) 6.86
CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res (2006) 6.35
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature (1994) 5.34
The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Res (2008) 4.63
Expression of luminal and basal cytokeratins in human breast carcinoma. J Pathol (2004) 3.80
Expression and amplification of cyclin genes in human breast cancer. Oncogene (1993) 3.79
Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell (2007) 3.44
Nestin expression--a property of multi-lineage progenitor cells? Cell Mol Life Sci (2004) 3.26
Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science (2006) 3.26
Nestin expression in hair follicle sheath progenitor cells. Proc Natl Acad Sci U S A (2003) 3.07
Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes. Hum Pathol (2006) 2.92
Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition. J Cell Sci (2005) 2.88
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia (2004) 2.60
The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer. Cancer Res (2004) 2.38
Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. Oncogene (2001) 2.33
An interaction between zyxin and alpha-actinin. J Cell Biol (1992) 2.23
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc Natl Acad Sci U S A (2007) 2.18
Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin. J Cell Biol (2003) 2.14
The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer. Mol Cell Biol Res Commun (1999) 1.88
Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma. Cancer Res (2001) 1.88
Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis. Cancer Res (2007) 1.76
Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance. Eur J Cancer (2006) 1.76
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis. Cancer Cell (2008) 1.75
Cyclins and breast cancer. J Mammary Gland Biol Neoplasia (2004) 1.73
Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition. Cancer Res (2008) 1.68
Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. Cancer Res (2005) 1.49
Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. Oncogene (1991) 1.45
Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. Oncogene (2004) 1.39
Cytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors. Mod Pathol (2005) 1.38
Basoluminal carcinoma: a new biologically and prognostically distinct entity between basal and luminal breast cancer. Clin Cancer Res (2006) 1.38
A mouse model of basal-like breast carcinoma with metaplastic elements. J Pathol (2007) 1.36
The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene (2002) 1.33
The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression. Proc Natl Acad Sci U S A (2008) 1.25
Basal phenotype of ductal carcinoma in situ: recognition and immunohistologic profile. Mod Pathol (2006) 1.22
Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells. Clin Cancer Res (1995) 1.18
Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia (2008) 1.18
Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors. Cancer Res (2007) 1.17
Tumor suppressor activity of RB and p53 genes in human breast carcinoma cells. Oncogene (1993) 1.15
BRCA1-associated tumorigenesis: what have we learned from knockout mice? Trends Genet (2001) 1.11
Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer. Am J Pathol (2004) 1.04
Cytokeratin 14 is expressed in immature cells in rat taste buds. J Mol Histol (2007) 1.02
Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland. J Cell Biol (1981) 1.01
Cyclin D1 and mammary carcinoma: new insights from transgenic mouse models. Breast Cancer Res (2001) 1.00
Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression. Cancer Res (2007) 0.98
Rapid development of tamoxifen-stimulated mutant p53 breast tumors (T47D) in athymic mice. Clin Cancer Res (2000) 0.95
Hepatocellular carcinoma expressing both hepatocellular and biliary markers also expresses cytokeratin 14, a marker of bipotential progenitor cells. J Hepatol (1999) 0.95
Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes. J Biol Chem (2004) 0.94
Novel identification of zyxin upregulations in the motile phenotype of hepatocellular carcinoma. Mod Pathol (2006) 0.91
Functional analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during development. Oncogene (2002) 0.91
Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2. Cancer Res (2005) 0.90
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma. Oncogene (2003) 0.88
Bovine mammary myoepithelial cells. 1. Isolation, culture, and characterization. J Dairy Sci (1992) 0.83
[Dysfunction of E-cadherin-catenin system in invasion and metastasis of colorectal cancer]. Nihon Geka Gakkai Zasshi (1998) 0.82
Establishment and characterization of a bovine mammary myoepithelial cell line. In Vitro Cell Dev Biol Anim (1996) 0.79
Bovine mammary myoepithelial cells. 2. Interactions with epithelial cells in vitro. J Dairy Sci (1992) 0.78
Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species. J Biol Chem (2004) 3.00
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia (2004) 2.60
Participation and enjoyment of leisure activities in school-aged children with cerebral palsy. Dev Med Child Neurol (2008) 2.18
Information transfer: what do decision makers want and need from researchers? Implement Sci (2007) 1.88
Should intensive care medicine itself be on the critical list? Chest (2009) 1.79
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem (2002) 1.56
Transition to adult-oriented health care: perspectives of youth and adults with complex physical disabilities. Phys Occup Ther Pediatr (2009) 1.56
Psychometric evaluation of the Participation and Environment Measure for Children and Youth. Dev Med Child Neurol (2011) 1.54
A comparison of shear bond strengths of orthodontic brackets using various light sources, light guides, and cure times. Am J Orthod Dentofacial Orthop (2002) 1.45
Occupational therapy interventions for chronic diseases: a scoping review. Am J Occup Ther (2011) 1.43
Predictors of change in participation rates following acquired brain injury: results of a longitudinal study. Dev Med Child Neurol (2012) 1.42
Comparative Effectiveness Research and Children With Cerebral Palsy: Identifying a Conceptual Framework and Specifying Measures. Pediatr Phys Ther (2016) 1.39
MRI screening before standard tissue plasminogen activator therapy is feasible and safe. Stroke (2005) 1.35
The Canadian Occupational Performance Measure: a research and clinical literature review. Can J Occup Ther (2004) 1.33
The birth of the Canadian Academy of Health Sciences. Clin Invest Med (2005) 1.33
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res (2003) 1.32
Intranasal administration of naloxone by paramedics. Prehosp Emerg Care (2002) 1.29
Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation. Mol Pharmacol (2009) 1.28
Determinants of life quality in school-age children with cerebral palsy. J Pediatr (2007) 1.28
A conceptual model of the factors affecting the recreation and leisure participation of children with disabilities. Phys Occup Ther Pediatr (2003) 1.28
Leisure activity preferences for 6- to 12-year-old children with cerebral palsy. Dev Med Child Neurol (2009) 1.19
Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein. Protein Expr Purif (2003) 1.13
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. J Pharmacol Exp Ther (2010) 1.13
Differences in patterns of participation between youths with cerebral palsy and typically developing peers. Am J Occup Ther (2009) 1.13
Determinants of participation in leisure activities in children and youth with cerebral palsy: systematic review. Phys Occup Ther Pediatr (2008) 1.11
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Autophagy (2014) 1.11
Community participation, supports, and barriers of school-age children with and without disabilities. Arch Phys Med Rehabil (2012) 1.05
The B56gamma3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition. J Biol Chem (2010) 1.05
How do changes in body functions and structures, activity, and participation relate in children with cerebral palsy? Dev Med Child Neurol (2008) 1.04
Development of the participation and environment measure for children and youth: conceptual basis. Disabil Rehabil (2012) 1.04
Scoping review of patient-centered care approaches in healthcare. BMC Health Serv Res (2014) 1.03
Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta. J Biol Chem (2006) 1.01
A review of evidence on the conceptual elements informing client-centred practice. Can J Occup Ther (2006) 1.01
Successful participation: the lived experience among children with disabilities. Can J Occup Ther (2007) 0.99
Porphyromonas gingivalis strain specific interactions with human coronary artery endothelial cells: a comparative study. PLoS One (2012) 0.98
Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression. Cancer Res (2007) 0.98
Simulation: about safety, not fantasy. Chest (2008) 0.98
The effect of the environment on participation of children and youth with disabilities: a scoping review. Disabil Rehabil (2013) 0.98
Intracranial EEG in temporal lobe epilepsy: location of seizure onset relates to degree of hippocampal pathology. Epilepsia (2004) 0.97
The Porphyromonas gingivalis clpB gene is involved in cellular invasion in vitro and virulence in vivo. FEMS Immunol Med Microbiol (2007) 0.95
αB-crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Mol Cancer Res (2011) 0.95
Mysteries and mazes: parents' experiences of children with developmental coordination disorder. Can J Occup Ther (2006) 0.95
A measure of community members' perceptions of the impacts of research partnerships in health and social services. Eval Program Plann (2009) 0.93
Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents. Mol Cancer Ther (2013) 0.92
Determinants of participation in leisure activities among adolescents with cerebral palsy. Res Dev Disabil (2013) 0.91
Reliability in the ratings of quality of life between parents and their children of school age with cerebral palsy. Qual Life Res (2008) 0.91
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. J Cell Biochem (2008) 0.90
A novel class of cyclin-dependent kinase inhibitors identified by molecular docking act through a unique mechanism. J Biol Chem (2009) 0.90
An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch. Cancer Lett (2012) 0.89
Impact of culture on children's community participation in Israel. Am J Occup Ther (2007) 0.89
The health and quality of life outcomes among youth and young adults with cerebral palsy. Arch Phys Med Rehabil (2010) 0.88
The effects of family-centred functional therapy on the occupational performance of children with cerebral palsy. Can J Occup Ther (2003) 0.88
A critical appraisal of literature reviews about the transition to adulthood for youth with disabilities. Phys Occup Ther Pediatr (2006) 0.88
Impact of caring for a school-aged child with a disability: understanding mothers' perspectives. Aust Occup Ther J (2010) 0.87
Identification of genes, including the gene encoding p27Kip1, regulated by serine 276 phosphorylation of the p65 subunit of NF-kappaB. Cancer Lett (2008) 0.87
Targeted applications of the Canadian Occupational Performance Measure. Can J Occup Ther (2005) 0.87
Porphyromonas gingivalis and the autophagic pathway: an innate immune interaction? Front Biosci (2008) 0.87
Behavioral difficulties in adolescents with cerebral palsy. J Child Neurol (2012) 0.87
Outcome measurement in pediatric rehabilitation. Phys Occup Ther Pediatr (2003) 0.86
Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein. Breast Cancer Res (2004) 0.86
Research utilization and evidence-based practice in occupational therapy: a scoping study. Am J Occup Ther (2013) 0.86
Level of motivation in mastering challenging tasks in children with cerebral palsy. Dev Med Child Neurol (2010) 0.85
Predictors of Change Over Time in the Activity Participation of Children and Youth with Physical Disabilities. Child Health Care (2009) 0.85
Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development. Biochemistry (2009) 0.85
Defining the effect and mediators of two knowledge translation strategies designed to alter knowledge, intent and clinical utilization of rehabilitation outcome measures: a study protocol [NCT00298727]. Implement Sci (2006) 0.85
Epithelial-to-mesenchymal transition confers pericyte properties on cancer cells. J Clin Invest (2016) 0.84
Behavioural problems in school age children with cerebral palsy. Eur J Paediatr Neurol (2011) 0.84
The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition. J Biol Chem (2013) 0.84
A trajectory of troubles: parents' impressions of the impact of developmental coordination disorder. Phys Occup Ther Pediatr (2007) 0.84
Neighbourhood influences on participation in activities among older adults with chronic health conditions. Health Place (2012) 0.84
Psychosocial determinants of out of school activity participation for children with and without physical disabilities. Phys Occup Ther Pediatr (2013) 0.84
Assembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes. Biochemistry (2013) 0.83
Youth and young adults with cerebral palsy: their use of physician and hospital services. Arch Phys Med Rehabil (2007) 0.82
Indicators of distress in families of children with cerebral palsy. Disabil Rehabil (2012) 0.82
Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints. J Cell Sci (2013) 0.82
Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-kappaB using in silico molecular docking. Cancer Lett (2009) 0.82
Serum YKL-40 concentrations in newly diagnosed multiple myeloma patients and YKL-40 expression in malignant plasma cells. Eur J Haematol (2006) 0.81
The patient handoff: medicine's Formula One moment. Chest (2008) 0.81
Self-reported mental health of mothers with a school-aged child with a disability in Victoria: a mixed method study. J Paediatr Child Health (2011) 0.80
Geographical patterns in the recreation and leisure participation of children and youth with cerebral palsy: a CAPE international collaborative network study. Dev Neurorehabil (2013) 0.80
Complexities during transitions to adulthood for youth with disabilities: person-environment interactions. Disabil Rehabil (2014) 0.80
Features and impacts of five multidisciplinary community-university research partnerships. Health Soc Care Community (2009) 0.80
Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development. Cancer Lett (2012) 0.80
Exploring and visualizing multidimensional data in translational research platforms. Brief Bioinform (2016) 0.79
Exploring the use of cognitive intervention for children with acquired brain injury. Phys Occup Ther Pediatr (2010) 0.79
Developmental and functional abilities in children with cerebral palsy as related to pattern and level of motor function. J Child Neurol (2010) 0.79
Picture me playing-a portrait of participation and enjoyment of leisure activities in adolescents with cerebral palsy. Res Dev Disabil (2013) 0.79
The relationship between manual ability and ambulation in adolescents with cerebral palsy. Phys Occup Ther Pediatr (2013) 0.79
Relationships between sleep disruptions, health and care responsibilities among mothers of school-aged children with disabilities. J Paediatr Child Health (2013) 0.79
The transition study: a look at youth and adults with cerebral palsy, spina bifida and acquired brain injury. Phys Occup Ther Pediatr (2006) 0.79
Play and be happy? Leisure participation and quality of life in school-aged children with cerebral palsy. Int J Pediatr (2012) 0.79
Recovery after hip fracture: what can we learn from the Canadian Occupational Performance Measure? Am J Occup Ther (2007) 0.78
Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest. Differentiation (2009) 0.78
Examination of the Perceived Efficacy and Goal Setting System (PEGS) with children with disabilities, their parents, and teachers. Am J Occup Ther (2006) 0.78
"Push" versus "Pull" for mobilizing pain evidence into practice across different health professions: a protocol for a randomized trial. Implement Sci (2012) 0.78
Pursuit of Complementary and Alternative Medicine Treatments in Adolescents With Cerebral Palsy. J Child Neurol (2013) 0.77