Published in J Biol Chem on August 08, 2013
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Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res (2006) 2.62
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LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells. Nat Cell Biol (2011) 1.76
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol (2013) 1.72
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression. Proc Natl Acad Sci U S A (2012) 1.59
LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis. Proc Natl Acad Sci U S A (2009) 1.58
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell (2011) 1.55
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A. Proc Natl Acad Sci U S A (2013) 1.50
MBT domain proteins in development and disease. Semin Cell Dev Biol (2009) 1.49
Histone demethylase LSD1 regulates neural stem cell proliferation. Mol Cell Biol (2010) 1.47
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol Cell (2012) 1.44
Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells. Mol Cell Biol (2011) 1.42
Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition. Mol Cell Biol (2011) 1.34
Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation. Mol Cell Biol (2009) 1.29
Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3. FEBS Lett (2007) 1.25
Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells. Oncogene (2012) 1.15
p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo. Mol Cell Biol (2008) 1.15
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function. Neoplasia (2009) 1.13
The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals. Free Radic Biol Med (2012) 1.08
Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation. EMBO J (2009) 1.00
SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. Genes Dev (2013) 0.97
Positive expression of LSD1 and negative expression of E-cadherin correlate with metastasis and poor prognosis of colon cancer. Dig Dis Sci (2013) 0.96
Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast. BMC Clin Pathol (2012) 0.92
H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development. PLoS Genet (2011) 0.88
Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program. J Biol Chem (2013) 0.85
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. J Biol Chem (2012) 0.83
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol (2009) 9.25
Epidemiology of human infections with avian influenza A(H7N9) virus in China. N Engl J Med (2013) 7.52
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Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol (2009) 4.49
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma. Acta Neuropathol (2009) 3.97
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J (2010) 3.90
Gradient-index meta-surfaces as a bridge linking propagating waves and surface waves. Nat Mater (2012) 3.42
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A (2009) 3.39
MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J Biol Chem (2010) 2.85
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia (2004) 2.60
High-efficiency broadband anomalous reflection by gradient meta-surfaces. Nano Lett (2012) 2.53
Non-continuous versus continuous wound drainage after total knee arthroplasty: a meta-analysis. Int Orthop (2013) 2.53
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res (2010) 2.52
Potential savings from greater use of $4 generic drugs. Arch Intern Med (2011) 2.48
The emergence of Ug99 races of the stem rust fungus is a threat to world wheat production. Annu Rev Phytopathol (2011) 2.35
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet (2003) 2.30
Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One (2008) 2.28
Catalytic carbene insertion into C-H bonds. Chem Rev (2010) 2.27
Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis. Mol Cell Biol (2007) 2.25
Structure of adeno-associated virus serotype 8, a gene therapy vector. J Virol (2007) 2.15
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat Struct Mol Biol (2013) 2.14
Entrapment of carbon dioxide in the active site of carbonic anhydrase II. J Biol Chem (2008) 1.98
Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. J Virol (2006) 1.97
BOLD study of stimulation-induced neural activity and resting-state connectivity in medetomidine-sedated rat. Neuroimage (2007) 1.91
Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China. Clin Infect Dis (2011) 1.87
High-efficiency broadband meta-hologram with polarization-controlled dual images. Nano Lett (2013) 1.85
Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism. Biochemistry (2007) 1.83
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. Genes Dev (2006) 1.79
Cooperative astrocyte and dendritic spine dynamics at hippocampal excitatory synapses. J Neurosci (2006) 1.79
Sex, depression, and risk of hospitalization and mortality in chronic obstructive pulmonary disease. Arch Intern Med (2007) 1.77
Solvent-mediated proton transfer in catalysis by carbonic anhydrase. Acc Chem Res (2007) 1.75
Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry (2007) 1.72
Human influenza A (H5N1) cases, urban areas of People's Republic of China, 2005-2006. Emerg Infect Dis (2007) 1.71
Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II. Biochemistry (2005) 1.69
Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation. Mol Cell Biol (2005) 1.65
Transcatheter closure of perimembranous ventricular septal defect in children: safety and efficiency with symmetric and asymmetric occluders. Catheter Cardiovasc Interv (2010) 1.61
Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. Clin Cancer Res (2009) 1.61
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Mol Cell (2007) 1.60
Increased genomic copy number of DEFA1/DEFA3 is associated with susceptibility to severe sepsis in Chinese Han population. Anesthesiology (2010) 1.58
Phylogenetic analysis of porcine epidemic diarrhea virus field strains prevailing recently in China. Arch Virol (2012) 1.57
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem (2002) 1.56
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Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol. Mol Cancer (2010) 1.50
Triggering receptor expressed on myeloid cells-2 protects against polymicrobial sepsis by enhancing bacterial clearance. Am J Respir Crit Care Med (2013) 1.49
Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation. EMBO J (2005) 1.48
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IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. J Clin Invest (2011) 1.46
Heparin binding induces conformational changes in Adeno-associated virus serotype 2. J Struct Biol (2008) 1.44
Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors. Proc Natl Acad Sci U S A (2008) 1.43
Structural characterization of the dual glycan binding adeno-associated virus serotype 6. J Virol (2010) 1.42
Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice. J Virol (2005) 1.41
The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer. Acta Crystallogr D Biol Crystallogr (2002) 1.39
Asymmetric somatic stem cells division plays a critical role in cell senescence. Med Hypotheses (2006) 1.38
Elucidation of the proton transport mechanism in human carbonic anhydrase II. J Am Chem Soc (2009) 1.37
Knowledge, attitudes and practices (KAP) relating to avian influenza in urban and rural areas of China. BMC Infect Dis (2010) 1.36
MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis. Mol Cancer Ther (2011) 1.33
Prolonged follow-up and CSF antibody titers in a patient with anti-NMDA receptor encephalitis. Neurology (2011) 1.33
A short, strong hydrogen bond in the active site of human carbonic anhydrase II. Biochemistry (2010) 1.33
Epigenetic blocking of an enhancer region controls irradiation-induced proapoptotic gene expression in Drosophila embryos. Dev Cell (2008) 1.33
Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. Genes Cancer (2010) 1.33
The notch regulator MAML1 interacts with p53 and functions as a coactivator. J Biol Chem (2007) 1.33
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res (2003) 1.32
Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys. Endocrinology (2012) 1.30
Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation. Free Radic Biol Med (2005) 1.29
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network. Gastroenterology (2010) 1.29
Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation. Mol Pharmacol (2009) 1.28
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease. EMBO Mol Med (2012) 1.28
Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease. Biochemistry (2004) 1.28
Neutron structure of human carbonic anhydrase II: implications for proton transfer. Biochemistry (2010) 1.26
Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus. J Bacteriol (2002) 1.24
Glucose oxidation modulates anoikis and tumor metastasis. Mol Cell Biol (2012) 1.23
Structural basis for the cAMP-dependent gating in the human HCN4 channel. J Biol Chem (2010) 1.22
Manipulating electromagnetic wave polarizations by anisotropic metamaterials. Phys Rev Lett (2007) 1.22
Access to and use of $4 generic programs in Medicare. J Gen Intern Med (2012) 1.22
p37 Induces tumor invasiveness. Mol Cancer Ther (2005) 1.21
Topical voriconazole as a novel treatment for fungal keratitis. Antimicrob Agents Chemother (2006) 1.20
Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2. J Leukoc Biol (2009) 1.20
Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance. Cancer Res (2013) 1.19
Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway. Oncogene (2004) 1.19
Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels. J Gen Physiol (2007) 1.19
PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. PLoS One (2011) 1.18
Structural insight into the unique properties of adeno-associated virus serotype 9. J Virol (2012) 1.18
Chemical rescue in catalysis by human carbonic anhydrases II and III. Biochemistry (2002) 1.18
Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation. J Biol Chem (2006) 1.17
Microwave absorption properties of carbon nanocoils coated with highly controlled magnetic materials by atomic layer deposition. ACS Nano (2012) 1.17
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallogr D Biol Crystallogr (2008) 1.17
Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 1.17
A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation. J Biol Chem (2004) 1.17
Genetic mapping of stem rust resistance gene Sr13 in tetraploid wheat (Triticum turgidum ssp. durum L.). Theor Appl Genet (2010) 1.17
Comparative analysis of adeno-associated virus capsid stability and dynamics. J Virol (2013) 1.16
Cemented versus uncemented hemiarthroplasty for femoral neck fractures in elderly patients: a meta-analysis. PLoS One (2013) 1.16