Published in Diabetes on November 04, 2008
IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells. J Exp Med (2010) 2.21
Activation of retinoid receptor-mediated signaling ameliorates diabetes-induced cardiac dysfunction in Zucker diabetic rats. J Mol Cell Cardiol (2013) 1.49
Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer. Cancer Immunol Immunother (2013) 1.43
All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus. PLoS One (2011) 1.20
Vitamin A and immune regulation: role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance. Mol Aspects Med (2011) 1.17
Vitamin A and retinoic acid in T cell-related immunity. Am J Clin Nutr (2012) 1.11
The impact of Th17 cells on transplant rejection and the induction of tolerance. Curr Opin Organ Transplant (2010) 1.07
Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation. Clin Exp Immunol (2009) 1.04
High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. J Cell Physiol (2012) 1.00
Retinoic acid signaling pathways in development and diseases. Bioorg Med Chem (2013) 0.99
Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice. J Clin Invest (2011) 0.98
Retinoic acid receptor-mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: role of the renin-angiotensin system. J Cell Physiol (2011) 0.91
Leukocyte homing, fate, and function are controlled by retinoic acid. Physiol Rev (2015) 0.88
Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditions. Cell Immunol (2012) 0.86
Seeing through the dark: New insights into the immune regulatory functions of vitamin A. Eur J Immunol (2015) 0.85
IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2. J Immunol (2013) 0.85
Retinoid metabolism and diabetes mellitus. Diabetes Metab J (2012) 0.83
Treg inducing adjuvants for therapeutic vaccination against chronic inflammatory diseases. Front Immunol (2013) 0.83
Retinoic Acid as a Modulator of T Cell Immunity. Nutrients (2016) 0.83
Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres. J Mater Chem B Mater Biol Med (2014) 0.82
Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques. J Neuroimmunol (2013) 0.80
New insight into the immunomodulatory mechanisms of Tretinoin in NMRI mice. Iran J Basic Med Sci (2014) 0.80
Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells. J Leukoc Biol (2013) 0.79
Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice. Cardiovasc Diabetol (2014) 0.77
Treating arthritis by immunomodulation: is there a role for regulatory T cells? Rheumatology (Oxford) (2010) 0.77
Taking a daily vitamin to prevent type 1 diabetes? Diabetes (2009) 0.77
All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study. Stem Cells Int (2015) 0.76
Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice. J Immunol (2015) 0.76
Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation. Biomed Res Int (2015) 0.76
Prevention and Reversal of Diabetes by All-Trans Retinoid Acid and Exendin-4 in NOD Mice. Int J Endocrinol (2014) 0.76
Retinoids: novel immunomodulators and tumour-suppressive agents? Br J Pharmacol (2012) 0.75
Positive evidence for vitamin A role in prevention of type 1 diabetes. World J Diabetes (2016) 0.75
Molecular Mechanisms of Retinoid Receptors in Diabetes-Induced Cardiac Remodeling. J Clin Med (2014) 0.75
Vitamin A: a missing link in diabetes? Diabetes Manag (Lond) (2015) 0.75
Clinical Potential of Regulatory T Cell Therapy in Liver Diseases: An Overview and Current Perspectives. Front Immunol (2016) 0.75
Immune response after autologous hematopoietic stem cell transplantation in type 1 diabetes mellitus. Stem Cell Res Ther (2017) 0.75
Butyrate and retinoic acid synergistically imprint mucosal-like dendritic cell development from bone marrow cells. Clin Exp Immunol (2017) 0.75
A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell (2000) 17.61
IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol (2007) 14.99
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science (2007) 12.79
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med (2007) 11.82
Increased expression of interleukin 17 in inflammatory bowel disease. Gut (2003) 9.16
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med (1996) 8.54
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol (2005) 7.44
FOXP3: of mice and men. Annu Rev Immunol (2006) 6.89
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol (2006) 6.82
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med (2007) 5.96
All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood (1990) 4.36
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med (2006) 3.57
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood (2007) 3.33
Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science (1990) 3.17
Death by a thousand cuts: granzyme pathways of programmed cell death. Annu Rev Immunol (2008) 2.97
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol (2007) 2.60
Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proc Natl Acad Sci U S A (1996) 2.53
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol (2005) 2.26
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes (1994) 2.16
Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc Natl Acad Sci U S A (1989) 2.15
Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation. Eur J Immunol (2007) 2.10
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J Exp Med (2004) 1.88
In vitamin A deficiency multiple mechanisms establish a regulatory T helper cell imbalance with excess Th1 and insufficient Th2 function. J Immunol (1994) 1.67
Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. J Exp Med (1998) 1.65
Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling. J Immunol (2002) 1.64
Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer. J Clin Invest (1992) 1.64
Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc Natl Acad Sci U S A (2001) 1.62
Therapy for acne vulgaris. N Engl J Med (1997) 1.52
Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. Proc Natl Acad Sci U S A (1997) 1.52
Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor. J Exp Med (2001) 1.32
Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis. Mol Pharmacol (2006) 1.16
Retinoic acid reduces autoimmune renal injury and increases survival in NZB/W F1 mice. J Immunol (2003) 1.11
Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J Nutr (2007) 1.11
IFN-gamma affects homing of diabetogenic T cells. J Immunol (2001) 1.10
IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. J Clin Invest (2000) 1.06
Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex. J Immunol (2001) 1.03
Decreased vitamin A levels in common variable immunodeficiency: vitamin A supplementation in vivo enhances immunoglobulin production and downregulates inflammatory responses. Eur J Clin Invest (2000) 1.01
Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid. Diabetes (2006) 0.96
Vitamin A deficiency exacerbates inflammation in a rat model of colitis through activation of nuclear factor-kappaB and collagen formation. J Nutr (2002) 0.90
Polarized development of memory cell-like IFN-gamma-producing cells in the absence of TCR zeta-chain. J Immunol (2005) 0.88
Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J Immunol (2004) 0.85
Vitamin A status affects the development of diabetes and insulitis in BB rats. Metabolism (1996) 0.84
Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction. Diabetes (1996) 0.82
Effector lymphocytes in islet cell autoimmunity. Rev Endocr Metab Disord (2003) 0.81
Effect of synthetic retinoid, TAC-101, on experimental autoimmune disease. Pharmacology (2003) 0.81
Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells. J Immunol (2005) 0.79
Mesenchymal stem cells suppress B-cell terminal differentiation. Exp Hematol (2009) 1.25
Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides. J Immunol (2003) 1.11
IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. J Exp Clin Cancer Res (2013) 1.07
Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes. J Immunol (2003) 1.03
A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. PLoS One (2008) 0.99
Venomic and transcriptomic analysis of centipede Scolopendra subspinipes dehaani. J Proteome Res (2012) 0.98
Identification and characterization of novel reptile cathelicidins from elapid snakes. Peptides (2008) 0.97
Regulatory T cells can mediate their function through the stimulation of APCs to produce immunosuppressive nitric oxide. J Immunol (2006) 0.95
Molecular characterization of Trimeresurus stejnegeri venom L-amino acid oxidase with potential anti-HIV activity. Biochem Biophys Res Commun (2003) 0.94
Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice. J Immunol (2004) 0.92
Isolation, expression and characterization of a novel dual serine protease inhibitor, OH-TCI, from king cobra venom. Peptides (2008) 0.91
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. PLoS One (2009) 0.90
Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs. J Proteome Res (2011) 0.89
Efficacy of OH-CATH30 and its analogs against drug-resistant bacteria in vitro and in mouse models. Antimicrob Agents Chemother (2012) 0.89
Polarized development of memory cell-like IFN-gamma-producing cells in the absence of TCR zeta-chain. J Immunol (2005) 0.88
Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells. Proc Natl Acad Sci U S A (2011) 0.87
Identification of novel semenogelin I-derived antimicrobial peptide from liquefied human seminal plasma. Peptides (2008) 0.86
Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2. Viral Immunol (2005) 0.85
Bm-TFF2, a trefoil factor protein with platelet activation activity from frog Bombina maxima skin secretions. Biochem Biophys Res Commun (2005) 0.84
Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection. Proc Natl Acad Sci U S A (2014) 0.83
Isolation and cloning of a metalloproteinase from king cobra snake venom. Toxicon (2007) 0.83
Purification and characterization of an irreversible serine protease inhibitor from skin secretions of Bufo andrewsi. Toxicon (2005) 0.83
Trefoil factor 1 gene alternations and expression in colorectal carcinomas. Tumori (2014) 0.83
Down-regulation of protease-activated receptor 4 in lung adenocarcinoma is associated with a more aggressive phenotype. Asian Pac J Cancer Prev (2013) 0.82
Regulatory function of a novel population of mouse autoantigen-specific Foxp3 regulatory T cells depends on IFN-gamma, NO, and contact with target cells. PLoS One (2009) 0.81
Frog albumin is expressed in skin and characterized as a novel potent trypsin inhibitor. Protein Sci (2005) 0.81
CD4+ CD25+ regulatory T cells prevent type 1 diabetes preceded by dendritic cell-dominant invasive insulitis by affecting chemotaxis and local invasiveness of dendritic cells. J Immunol (2010) 0.81
Comparative analyses of differentially induced T-cell receptor-mediated phosphorylation pathways in T lymphoma cells. Exp Biol Med (Maywood) (2010) 0.80
Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways. J Immunol (2004) 0.80
Molecular cloning and characterization of a complement-depleting factor from king cobra, Ophiophagus hannah. Toxicon (2012) 0.80
Naturally occurring antimicrobial peptide OH-CATH30 selectively regulates the innate immune response to protect against sepsis. J Med Chem (2013) 0.80
Image-guided analyses reveal that non-CD4 splenocytes contribute to CD4+ T cell-mediated inflammation leading to islet destruction by altering their local function and not systemic trafficking patterns. Mol Imaging (2007) 0.80
Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals. PLoS One (2013) 0.79
Isolation and preliminary characterization of a 22-kDa protein with trypsin inhibitory activity from toad Bufo andrewsi skin. Toxicon (2005) 0.79
Purification, characterization and gene cloning of Da-36, a novel serine protease from Deinagkistrodon acutus venom. Toxicon (2013) 0.79
Maximins S, a novel group of antimicrobial peptides from toad Bombina maxima. Biochem Biophys Res Commun (2005) 0.78
Structure-function relationship of king cobra cathelicidin. Peptides (2010) 0.78
A snake venom metalloproteinase that inhibited cell proliferation and induced morphological changes of ECV304 cells. Toxicon (2006) 0.78
Blood cells as targets of snake toxins. Blood Cells Mol Dis (2006) 0.78
Molecular characterization of L-amino acid oxidase from king cobra venom. Toxicon (2007) 0.78
Molecular cloning of serine proteases from elapid snake venoms. Toxicon (2007) 0.78
Apoptotic activity of frog Bombina maxima skin albumin. Comp Biochem Physiol B Biochem Mol Biol (2005) 0.77
Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A (2012) 0.77
Two bacterial infection models in tree shrew for evaluating the efficacy of antimicrobial agents. Dongwuxue Yanjiu (2012) 0.77
Acute toxicity of betagamma-CAT, a naturally existing non-lens betagamma-crystallin and trefoil factor complex from frog Bombina maxima skin secretions. Toxicon (2008) 0.77
Cloning of two novel P-III class metalloproteinases from Trimeresurus stejnegeri venom gland. Toxicon (2006) 0.77
Mesenchymal stem cells facilitate mixed hematopoietic chimerism induction and prevent onset of diabetes in nonobese diabetic mice. Pancreas (2011) 0.77
Jerdonuxin, a novel snaclec (snake C-type lectin) with platelet aggregation activity from Trimeresurus jerdonii venom. Toxicon (2010) 0.77
Differential expression and subcellular localization of Prohibitin 1 are related to tumorigenesis and progression of non-small cell lung cancer. Int J Clin Exp Pathol (2013) 0.76
Purification of a lysozyme from skin secretions of Bufo andrewsi. Comp Biochem Physiol C Toxicol Pharmacol (2005) 0.75
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. Toxicon (2013) 0.75
Bacterial expression and purification of biologically active human TFF2. Dongwuxue Yanjiu (2012) 0.75
[Expression and identification of Bm-TFF2 in Pichia pastoris]. Dongwuxue Yanjiu (2010) 0.75
Cloning of novel bombesin precursor cDNAs from skin of Bombina maxima. Regul Pept (2005) 0.75
Development of T cells expressing an altered TCR complex. Eur J Immunol (2003) 0.75
[Status of vaccination against hepatitis B among postgraduate students in medical higher education institutions in Guangzhou]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi (2007) 0.75
A novel heme-containing protein with anti-HIV-1 activity from skin secretions of Bufo andrewsi. Toxicon (2005) 0.75
[Expression of Bm-TFF2 mutants in Escherichia coli and their cell migration-promoting activity]. Dongwuxue Yanjiu (2011) 0.75
Biological activities of skin secretions of the salamander Tylototriton verrucosus. J Nat Toxins (2002) 0.75