Intraductal papillary mucinous neoplasm of the pancreas with loss of mismatch repair in a patient with Lynch syndrome.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 2631097)

Published in Am J Surg Pathol on February 01, 2009

Authors

Jennifer A Sparr1, Prathap Bandipalliam, Mark S Redston, Sapna Syngal

Author Affiliations

1: Division of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Articles cited by this

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology (1999) 11.94

Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer (1999) 6.73

The molecular basis of Turcot's syndrome. N Engl J Med (1995) 6.65

Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet (1999) 4.16

Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer (1993) 3.86

Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroenterology (1996) 3.54

The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer (2008) 2.95

STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol (2001) 1.89

High incidence of extrapancreatic neoplasms in patients with intraductal papillary mucinous neoplasms. Arch Surg (2006) 1.78

Precursors to pancreatic cancer. Gastroenterol Clin North Am (2007) 1.75

Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity. Am J Pathol (2000) 1.69

Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer). Cancer (1991) 1.48

The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncystic carcinoma and ductal adenocarcinoma. Am J Surg Pathol (2001) 1.48

Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+. Am J Pathol (1998) 1.42

Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: a family study. Br J Cancer (1985) 1.34

Extrapancreatic neoplasms occur with unusual frequency in patients with intraductal papillary mucinous tumors of the pancreas. Am J Gastroenterol (1999) 1.28

Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. Cancer Res (2001) 1.20

Incidence of additional primary cancers in patients with invasive intraductal papillary mucinous neoplasms and sporadic pancreatic adenocarcinomas. J Am Coll Surg (2007) 1.12

Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol (2006) 1.02

Intraductal papillary mucinous neoplasm of the pancreas in a patient with attenuated familial adenomatous polyposis. J Clin Pathol (2005) 1.02

Pancreatic mucinous noncystic (colloid) carcinomas and intraductal papillary mucinous carcinomas are usually microsatellite stable. Mod Pathol (2003) 0.93

Correlation between patterns of DNA mismatch repair hmlh1 and hmsh2 protein expression and progression of dysplasia in intraductal papillary mucinous neoplasms of the pancreas. Virchows Arch (2004) 0.85

Articles by these authors

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev (2003) 8.27

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A (2006) 5.90

High-resolution characterization of the pancreatic adenocarcinoma genome. Proc Natl Acad Sci U S A (2004) 3.75

ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov (2011) 3.27

American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. J Clin Oncol (2014) 3.07

Does this patient have a family history of cancer? An evidence-based analysis of the accuracy of family cancer history. JAMA (2004) 2.99

Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma. J Invest Dermatol (2006) 2.87

Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population. Cancer Prev Res (Phila) (2010) 2.86

Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology (2009) 2.75

Prediction of MLH1 and MSH2 mutations in Lynch syndrome. JAMA (2006) 2.73

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterology (2012) 2.69

Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res (2002) 2.33

Risk of pancreatic cancer in families with Lynch syndrome. JAMA (2009) 2.32

A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med (2008) 2.31

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts. Gut (2012) 2.17

A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res (2002) 2.07

Pancreatic cancer genetic epidemiology consortium. Cancer Epidemiol Biomarkers Prev (2006) 2.04

Obesity increases the risks of diverticulitis and diverticular bleeding. Gastroenterology (2008) 2.01

O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors. Clin Cancer Res (2009) 2.00

Mutant TP53 in duodenal samples of pancreatic juice from patients with pancreatic cancer or high-grade dysplasia. Clin Gastroenterol Hepatol (2012) 1.99

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. Lancet Oncol (2010) 1.98

The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history. Gastroenterology (2010) 1.88

Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients. Clin Gastroenterol Hepatol (2004) 1.76

Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk. Genet Med (2011) 1.70

Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. Cancer Prev Res (Phila) (2012) 1.65

Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer. J Mol Diagn (2004) 1.62

Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy. Am J Gastroenterol (2009) 1.62

Knowledge of quality performance measures associated with endoscopy among gastroenterology trainees and the impact of a web-based intervention. Gastrointest Endosc (2012) 1.59

Risk factors for mortality in lower intestinal bleeding. Clin Gastroenterol Hepatol (2008) 1.55

Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome. Obstet Gynecol (2005) 1.50

Successful treatment of cap polyposis with infliximab. Gastroenterology (2004) 1.49

Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying. Cancer Prev Res (Phila) (2008) 1.47

Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology (2010) 1.46

Nut, corn, and popcorn consumption and the incidence of diverticular disease. JAMA (2008) 1.46

The comprehensiveness of family cancer history assessments in primary care. Community Genet (2007) 1.42

Impact of preoperative staging and chemoradiation versus postoperative chemoradiation on outcome in patients with rectal cancer: a decision analysis. J Natl Cancer Inst (2004) 1.42

Hereditary colorectal cancer syndromes. Cancer Causes Control (2005) 1.40

Factors associated with enrollment in cancer genetics research. Cancer Epidemiol Biomarkers Prev (2006) 1.31

Hereditary pancreatic cancer. Gastroenterology (2010) 1.31

Cancer risk assessment: quality and impact of the family history interview. Am J Prev Med (2004) 1.30

Timing of colonoscopy: impact on length of hospital stay in patients with acute lower intestinal bleeding. Am J Gastroenterol (2003) 1.28

Colorectal cancers with microsatellite instability display unique miRNA profiles. Clin Cancer Res (2011) 1.27

F18-fluorodeoxyglucose-positron emission tomography/computed tomography screening in Li-Fraumeni syndrome. JAMA (2008) 1.26

Sharing genetic test results in Lynch syndrome: communication with close and distant relatives. Clin Gastroenterol Hepatol (2008) 1.20

Early predictors of severity in acute lower intestinal tract bleeding. Arch Intern Med (2003) 1.19

Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States. Cancer Epidemiol Biomarkers Prev (2008) 1.16

Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients. Gastroenterology (2007) 1.16

Elevated risk of prostate cancer among men with Lynch syndrome. J Clin Oncol (2013) 1.14

Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases. Cancer Res (2009) 1.14

Enhanced retrieval of DNA from human fecal samples results in improved performance of colorectal cancer screening test. J Mol Diagn (2004) 1.11

Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer). Cancer Prev Res (Phila) (2008) 1.11

Determinants of colorectal cancer screening in women undergoing mammography. Am J Gastroenterol (2003) 1.10

Colorectal cancer in young adults. Dig Dis Sci (2014) 1.08

Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome. Gastroenterology (2006) 1.08

Recurrence and variability of germline EPCAM deletions in Lynch syndrome. Hum Mutat (2011) 1.07

Inherited colorectal cancer syndromes. Cancer J (2011) 1.06

Gastric cancer in individuals with Li-Fraumeni syndrome. Genet Med (2011) 1.05

Validation of a clinical prediction rule for severe acute lower intestinal bleeding. Am J Gastroenterol (2005) 1.04

Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome. Am J Gastroenterol (2010) 1.03

The impact of family history of diabetes on glucose testing and counseling behavior in primary care. Diabetes Care (2004) 1.02

Genetic testing in gastroenterology: Lynch syndrome. Best Pract Res Clin Gastroenterol (2009) 1.02

Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer. Gut (2012) 0.99

Predictors of utilization of early colonoscopy vs. radiography for severe lower intestinal bleeding. Gastrointest Endosc (2005) 0.98

Colon cancer screening strategies. Curr Opin Gastroenterol (2005) 0.98

Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry. JAMA Oncol (2015) 0.96

Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. J Clin Oncol (2009) 0.96

Colorectal cancer screening: prevalence among low-income groups with health insurance. Health Aff (Millwood) (2009) 0.96

Recently identified colon cancer predispositions: MYH and MSH6 mutations. Semin Oncol (2007) 0.94

Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome. Gynecol Oncol (2012) 0.94

Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the U.S. Multi-Society Task Force on Colorectal Cancer. Gastrointest Endosc (2014) 0.94

Risk assessment, genetic testing, and management of Lynch syndrome. J Natl Compr Canc Netw (2010) 0.92

Screening patients with colorectal cancer for Lynch syndrome: what are we waiting for? J Clin Oncol (2012) 0.92

Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis. Am J Gastroenterol (2007) 0.90

Performance of PREMM(1,2,6), MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases. Genet Med (2012) 0.87

Racial and ethnic variations in the effects of family history of colorectal cancer on screening compliance. Gastroenterology (2013) 0.86

Clinical presentation correlates with the type of mismatch repair gene involved in hereditary nonpolyposis colon cancer. Gastroenterology (2004) 0.86

Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer. Dis Colon Rectum (2014) 0.85

Colorectal cancer screening awareness and intentions among low income, sociodemographically diverse adults under age 50. Cancer Causes Control (2008) 0.85

Identification of germline genomic copy number variation in familial pancreatic cancer. Hum Genet (2012) 0.85

Correlation of polyp number and family history of colon cancer with germline MYH mutations. Clin Gastroenterol Hepatol (2005) 0.84

Prediction models in Lynch syndrome. Fam Cancer (2013) 0.84

Data reduction for prediction: a case study on robust coding of age and family history for the risk of having a genetic mutation. Stat Med (2007) 0.83

Adenomas in young patients: what is the optimal evaluation? Am J Gastroenterol (2005) 0.81

Clinical guidelines versus universal molecular testing: are we ready to choose an optimal strategy for Lynch syndrome identification? Am J Gastroenterol (2008) 0.80

Recurrences are common after endoscopic ampullectomy for adenoma in the familial adenomatous polyposis (FAP) syndrome. Surg Endosc (2014) 0.80

Linkage analysis of chromosome 4 in families with familial pancreatic cancer. Cancer Biol Ther (2007) 0.80

Multivitamin use among multi-ethnic, low-income adults. Cancer Causes Control (2009) 0.79

An American founder mutation in MLH1. Int J Cancer (2011) 0.79

Surveillance of patients at high risk for colorectal cancer. Med Clin North Am (2005) 0.78

One less thing to worry about: the shrinking spectrum of tumors in BRCA founder mutation carriers. J Natl Cancer Inst (2004) 0.78

Dysplasia in Barrett esophagus. Cancer (2004) 0.78

Attitudes toward childbearing and prenatal testing in individuals undergoing genetic testing for Lynch syndrome. Fam Cancer (2011) 0.77