Thomas O Metz

Author PubWeight™ 54.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics. PLoS Pathog 2010 2.48
2 A statistical framework for protein quantitation in bottom-up MS-based proteomics. Bioinformatics 2009 2.07
3 Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics. Anal Chem 2005 1.87
4 Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes 2009 1.51
5 Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. PLoS Pathog 2012 1.45
6 Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation. Mol Syst Biol 2012 1.41
7 Combined statistical analyses of peptide intensities and peptide occurrences improves identification of significant peptides from MS-based proteomics data. J Proteome Res 2010 1.34
8 A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease. J Proteome Res 2009 1.31
9 Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications. Diabetes 2012 1.24
10 A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation. J Biol Chem 2001 1.19
11 Enrichment and analysis of nonenzymatically glycated peptides: boronate affinity chromatography coupled with electron-transfer dissociation mass spectrometry. J Proteome Res 2007 1.17
12 Improved quality control processing of peptide-centric LC-MS proteomics data. Bioinformatics 2011 1.15
13 A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection. PLoS One 2013 1.14
14 Application of electron transfer dissociation mass spectrometry in analyses of non-enzymatically glycated peptides. Rapid Commun Mass Spectrom 2007 1.13
15 Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease. J Proteome Res 2003 1.11
16 Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J Virol 2013 1.08
17 Separation and classification of lipids using differential ion mobility spectrometry. J Am Soc Mass Spectrom 2011 1.07
18 In silico identification software (ISIS): a machine learning approach to tandem mass spectral identification of lipids. Bioinformatics 2012 1.06
19 Elimination of systematic mass measurement errors in liquid chromatography-mass spectrometry based proteomics using regression models and a priori partial knowledge of the sample content. Anal Chem 2007 1.06
20 Making broad proteome protein measurements in 1-5 min using high-speed RPLC separations and high-accuracy mass measurements. Anal Chem 2005 1.04
21 Capillary LC coupled with high-mass measurement accuracy mass spectrometry for metabolic profiling. Anal Chem 2007 1.04
22 Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. MBio 2013 1.04
23 A reversed-phase capillary ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for comprehensive top-down/bottom-up lipid profiling. Anal Bioanal Chem 2012 1.03
24 Salmonella modulates metabolism during growth under conditions that induce expression of virulence genes. Mol Biosyst 2013 1.02
25 Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranes. J Proteome Res 2008 1.01
26 A comparative analysis of computational approaches to relative protein quantification using peptide peak intensities in label-free LC-MS proteomics experiments. Proteomics 2012 1.01
27 Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis. J Virol 2011 1.00
28 Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. J Exp Med 2012 0.98
29 Application of the accurate mass and time tag approach in studies of the human blood lipidome. J Chromatogr B Analyt Technol Biomed Life Sci 2008 0.98
30 GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data. Bioinformatics 2013 0.98
31 MultiAlign: a multiple LC-MS analysis tool for targeted omics analysis. BMC Bioinformatics 2013 0.95
32 Targeted protein degradation by Salmonella under phagosome-mimicking culture conditions investigated using comparative peptidomics. Mol Cell Proteomics 2007 0.95
33 Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics. J Proteome Res 2012 0.94
34 Comprehensive identification of glycated peptides and their glycation motifs in plasma and erythrocytes of control and diabetic subjects. J Proteome Res 2011 0.93
35 Decreased abundance of type III secretion system-inducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae. Proc Natl Acad Sci U S A 2014 0.92
36 Analysis of non-enzymatically glycated peptides: neutral-loss-triggered MS(3) versus multi-stage activation tandem mass spectrometry. Rapid Commun Mass Spectrom 2008 0.90
37 The succinated proteome. Mass Spectrom Rev 2013 0.89
38 Technologies and approaches to elucidate and model the virulence program of salmonella. Front Microbiol 2011 0.88
39 A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. PLoS One 2013 0.87
40 Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice. BMC Syst Biol 2013 0.86
41 A multi-omic systems approach to elucidating Yersinia virulence mechanisms. Mol Biosyst 2012 0.86
42 Metabolomic response of human skin tissue to low dose ionizing radiation. Mol Biosyst 2012 0.85
43 Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics. Rapid Commun Mass Spectrom 2011 0.85
44 Sequential projection pursuit principal component analysis--dealing with missing data associated with new -omics technologies. Biotechniques 2013 0.84
45 Perturbations in the lipid profile of individuals with newly diagnosed type 1 diabetes mellitus: lipidomics analysis of a Diabetes Antibody Standardization Program sample subset. Clin Biochem 2010 0.82
46 Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease. Mol Cell Proteomics 2004 0.82
47 The fungus gardens of leaf-cutter ants undergo a distinct physiological transition during biomass degradation. Environ Microbiol Rep 2014 0.82
48 Improved methods for the enrichment and analysis of glycated peptides. Anal Chem 2008 0.81
49 Performing comparative peptidomics analyses of Salmonella from different growth conditions. Methods Mol Biol 2010 0.78
50 Studying Salmonellae and Yersiniae host-pathogen interactions using integrated 'omics and modeling. Curr Top Microbiol Immunol 2013 0.76
51 Development of a fibrinogen-specific sandwich enzyme-linked immunosorbent assay microarray assay for distinguishing between blood plasma and serum samples. Anal Biochem 2011 0.76
52 LIQUID: an-open source software for identifying lipids in LC-MS/MS-based lipidomics data. Bioinformatics 2017 0.76
53 Measurement of fructose-asparagine concentrations in human and animal foods. J Agric Food Chem 2017 0.75
54 A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants. bioRxiv 2022 0.75