Published in Bioorg Med Chem on October 17, 2008
Cyano Diels-Alder and cyano ene reactions. Applications in a formal [2 + 2 + 2] cycloaddition strategy for the synthesis of pyridines. J Am Chem Soc (2010) 0.89
3-Cyano-3-aza-β-amino Acid Derivatives as Inhibitors of Human Cysteine Cathepsins. ACS Med Chem Lett (2014) 0.78
TERT promoter mutations in familial and sporadic melanoma. Science (2013) 7.82
Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction. J Clin Oncol (2009) 4.38
Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial. Lancet (2011) 3.54
Early experience alters brain function and structure. Pediatrics (2004) 3.08
Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism. Pharmacogenetics (2002) 2.68
Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients. Eur Urol (2010) 2.49
Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics (2004) 2.32
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nat Med (2009) 2.08
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. Hum Mol Genet (2008) 1.98
Safety and efficacy of exercise training in various forms of pulmonary hypertension. Eur Respir J (2012) 1.83
Is atherosclerosis in diabetes and impaired fasting glucose driven by elevated LDL cholesterol or by decreased HDL cholesterol? Diabetes Care (2005) 1.79
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. Diabetes (2005) 1.75
Assessment and prognostic relevance of right ventricular contractile reserve in patients with severe pulmonary hypertension. Circulation (2013) 1.62
2-Fluoro-5-(4-fluoro-phen-yl)pyridine. Acta Crystallogr Sect E Struct Rep Online (2012) 1.58
Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some yemeni medicinal plants. Evid Based Complement Alternat Med (2008) 1.56
Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus. Mol Microbiol (2010) 1.49
Outcome of surgery for primary hyperaldosteronism. World J Surg (2011) 1.47
The stringent response of Staphylococcus aureus and its impact on survival after phagocytosis through the induction of intracellular PSMs expression. PLoS Pathog (2012) 1.46
Antimicrobial activity of some medicinal plants of the island Soqotra. J Ethnopharmacol (2005) 1.45
Deficits in the management of patients with adrenocortical carcinoma in Germany. Dtsch Arztebl Int (2010) 1.44
Reduced complication rate after modified binding purse-string-mattress sutures pancreatogastrostomy versus duct-to-mucosa pancreaticojejunostomy. Surgeon (2013) 1.41
Methyl 5-chloro-2-hydr-oxy-3-(4-methoxy-phen-yl)-4,6-dimethyl-benzoate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.39
Niemann-Pick disease type C clinical database: cognitive and coordination deficits are early disease indicators. Orphanet J Rare Dis (2013) 1.33
Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. J Ethnopharmacol (2007) 1.32
Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23. Kidney Int (2002) 1.32
Role of the (p)ppGpp synthase RSH, a RelA/SpoT homolog, in stringent response and virulence of Staphylococcus aureus. Infect Immun (2010) 1.29
Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra. BMC Complement Altern Med (2009) 1.29
Familial pancreatic cancer--current knowledge. Nat Rev Gastroenterol Hepatol (2012) 1.27
Nitric oxide stress induces different responses but mediates comparable protein thiol protection in Bacillus subtilis and Staphylococcus aureus. J Bacteriol (2008) 1.27
5-(4-Chloro-phen-yl)-2-fluoro-pyridine. Acta Crystallogr Sect E Struct Rep Online (2012) 1.24
Transcriptome and functional analysis of the eukaryotic-type serine/threonine kinase PknB in Staphylococcus aureus. J Bacteriol (2009) 1.22
Mutations in ROGDI Cause Kohlschütter-Tönz Syndrome. Am J Hum Genet (2012) 1.21
Thuja occidentalis (Arbor vitae): A Review of its Pharmaceutical, Pharmacological and Clinical Properties. Evid Based Complement Alternat Med (2005) 1.19
Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis. Nat Commun (2010) 1.19
Assessment of selected Yemeni medicinal plants for their in vitro antimicrobial, anticancer, and antioxidant activities. Pharm Biol (2010) 1.18
SuperToxic: a comprehensive database of toxic compounds. Nucleic Acids Res (2008) 1.17
Genome-wide responses to carbonyl electrophiles in Bacillus subtilis: control of the thiol-dependent formaldehyde dehydrogenase AdhA and cysteine proteinase YraA by the MerR-family regulator YraB (AdhR). Mol Microbiol (2008) 1.16
The metabolic syndrome, insulin resistance, and cardiovascular risk in diabetic and nondiabetic patients. J Clin Endocrinol Metab (2005) 1.15
Metaproteomics of a gutless marine worm and its symbiotic microbial community reveal unusual pathways for carbon and energy use. Proc Natl Acad Sci U S A (2012) 1.14
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues. J Pathol (2012) 1.14
Surgical management of pancreatic endocrine tumors. Nat Rev Clin Oncol (2009) 1.13
Diamide triggers mainly S Thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus. J Bacteriol (2009) 1.12
Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy. PLoS One (2010) 1.12
Lipase activity in insect oral secretions mediates defense responses in Arabidopsis. Plant Physiol (2011) 1.11
Adult Treatment Panel III 2001 but not International Diabetes Federation 2005 criteria of the metabolic syndrome predict clinical cardiovascular events in subjects who underwent coronary angiography. Diabetes Care (2006) 1.10
Advantage of upregulation of succinate dehydrogenase in Staphylococcus aureus biofilms. J Bacteriol (2010) 1.10
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival. EMBO Mol Med (2010) 1.09
Familial temporal lobe epilepsy with aphasic seizures and linkage to chromosome 10q22-q24. Epilepsia (2002) 1.09
A defect in menadione biosynthesis induces global changes in gene expression in Staphylococcus aureus. J Bacteriol (2008) 1.07
Assessment of antimalarial activity against Plasmodium falciparum and phytochemical screening of some Yemeni medicinal plants. Evid Based Complement Alternat Med (2007) 1.07
German national case collection for familial pancreatic cancer (FaPaCa): ten years experience. Fam Cancer (2011) 1.06
Lyngbyazothrins A-D, antimicrobial cyclic undecapeptides from the cultured Cyanobacterium lyngbya sp. J Nat Prod (2009) 1.06
An aggressive surgical approach leads to long-term survival in patients with pancreatic endocrine tumors. Ann Surg (2006) 1.06
Characterization of the oxygen-responsive NreABC regulon of Staphylococcus aureus. J Bacteriol (2008) 1.05
5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex. Eur J Gastroenterol Hepatol (2010) 1.04
Global analysis of the Staphylococcus aureus response to mupirocin. Antimicrob Agents Chemother (2011) 1.04
A protocol for the investigation of the intracellular Staphylococcus aureus metabolome. Anal Biochem (2010) 1.03
Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations. Respir Res (2011) 1.01
Phytochemical screening and antiviral activity of some medicinal plants from the island Soqotra. Phytother Res (2006) 1.01
Depletion of thiol-containing proteins in response to quinones in Bacillus subtilis. Mol Microbiol (2008) 1.01
A metabolomics and proteomics study of the adaptation of Staphylococcus aureus to glucose starvation. Mol Biosyst (2011) 0.99
A metabolomic view of Staphylococcus aureus and its ser/thr kinase and phosphatase deletion mutants: involvement in cell wall biosynthesis. Chem Biol (2010) 0.99
Familial pancreatic cancer syndromes. Endocrinol Metab Clin North Am (2006) 0.99
The novel human SHOX allelic variant database. Hum Mutat (2007) 0.99
Antiviral Terpenoid Constituents of Ganoderma pfeifferi. J Nat Prod (2005) 0.99
Outcome of duodenopancreatic resections in patients with multiple endocrine neoplasia type 1. Ann Surg (2005) 0.98
Pyruvate formate lyase acts as a formate supplier for metabolic processes during anaerobiosis in Staphylococcus aureus. J Bacteriol (2010) 0.98
Ethyl 4-chloro-2'-fluoro-3-hy-droxy-5-methyl-biphenyl-2-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online (2011) 0.98
Surface molecules on HaCaT keratinocytes after interaction with non-thermal atmospheric pressure plasma. Cell Biol Int (2012) 0.97
Characterization of central carbon metabolism of Streptococcus pneumoniae by isotopologue profiling. J Biol Chem (2011) 0.96
A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults. Hepatology (2008) 0.96
Chemical characterization of soil extract as growth media for the ecophysiological study of bacteria. Appl Microbiol Biotechnol (2009) 0.96
Impact of non-thermal plasma treatment on MAPK signaling pathways of human immune cell lines. Immunobiology (2013) 0.96
The human pseudoautosomal regions: a review for genetic epidemiologists. Eur J Hum Genet (2008) 0.96
Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients. Clin Rheumatol (2004) 0.95
Plasma Medicine - its perspective for wound therapy. GMS Krankenhhyg Interdiszip (2008) 0.95
Influence of non-thermal atmospheric pressure plasma on cellular structures and processes in human keratinocytes (HaCaT). J Dermatol Sci (2013) 0.94
Proteolysis during long-term glucose starvation in Staphylococcus aureus COL. Proteomics (2009) 0.94
Sensitization of melanoma cells for death ligand-induced apoptosis by an indirubin derivative--Enhancement of both extrinsic and intrinsic apoptosis pathways. Biochem Pharmacol (2010) 0.93
Exometabolome analysis identifies pyruvate dehydrogenase as a target for the antibiotic triphenylbismuthdichloride in multiresistant bacterial pathogens. J Biol Chem (2011) 0.93
Exercise training in pulmonary arterial hypertension associated with connective tissue diseases. Arthritis Res Ther (2012) 0.93
Screening of patients with multiple endocrine neoplasia type 1 (MEN-1): a critical analysis of its value. World J Surg (2009) 0.92
6-thioguanosine diphosphate and triphosphate levels in red blood cells and response to azathioprine therapy in Crohn's disease. Clin Gastroenterol Hepatol (2005) 0.92
Functional relevance of DNA polymorphisms within the promoter region of the prion protein gene and their association to BSE infection. FASEB J (2007) 0.92
Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders. Pharmacogenet Genomics (2009) 0.92
Non-thermal atmospheric-pressure plasma can influence cell adhesion molecules on HaCaT-keratinocytes. Exp Dermatol (2010) 0.91
Balticols A-F, new naphthalenone derivatives with antiviral activity, from an ascomycetous fungus. Chem Biodivers (2009) 0.91
Synthesis and structure-activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents. Bioorg Med Chem (2005) 0.91
The human SHOX mutation database. Hum Mutat (2002) 0.90
Screening for new metabolites from marine microorganisms. Adv Biochem Eng Biotechnol (2005) 0.90