Chronic stress, drug use, and vulnerability to addiction.

Cognitive neuroscience of self-regulation failure. Trends Cogn Sci (2011) 2.89

Disrupted ventromedial prefrontal function, alcohol craving, and subsequent relapse risk. JAMA Psychiatry (2013) 2.54

The relationship between discrimination and substance use disorders among lesbian, gay, and bisexual adults in the United States. Am J Public Health (2010) 2.46

Dynorphin, stress, and depression. Brain Res (2009) 2.45

Modeling stress and drug craving in the laboratory: implications for addiction treatment development. Addict Biol (2008) 2.06

Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. Arch Gen Psychiatry (2011) 2.01

Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front Neuroanat (2011) 1.85

Stressful life experiences, alcohol consumption, and alcohol use disorders: the epidemiologic evidence for four main types of stressors. Psychopharmacology (Berl) (2011) 1.83

Social deprivation enhances VTA synaptic plasticity and drug-induced contextual learning. Neuron (2013) 1.64

Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther (2010) 1.62

Increased serum brain-derived neurotrophic factor is predictive of cocaine relapse outcomes: a prospective study. Biol Psychiatry (2011) 1.61

Neuroscience of behavioral and pharmacological treatments for addictions. Neuron (2011) 1.57

Influence of affective manipulations on cigarette craving: a meta-analysis. Addiction (2013) 1.56

Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies. Neurosci Biobehav Rev (2013) 1.54

Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization. Biol Psychiatry (2011) 1.54

Shared brain vulnerabilities open the way for nonsubstance addictions: carving addiction at a new joint? Ann N Y Acad Sci (2010) 1.46

Effects of stress on alcohol drinking: a review of animal studies. Psychopharmacology (Berl) (2011) 1.33

Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels. Diabetes Care (2012) 1.32

Stress as a common risk factor for obesity and addiction. Biol Psychiatry (2013) 1.32

Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment. Arch Pediatr Adolesc Med (2011) 1.31

Interoception and drug addiction. Neuropharmacology (2013) 1.30

Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions. Biol Psychiatry (2012) 1.29

The effects of stress on physical activity and exercise. Sports Med (2014) 1.28

Prenatal cocaine exposure and gray matter volume in adolescent boys and girls: relationship to substance use initiation. Biol Psychiatry (2013) 1.27

Corticotropin-releasing factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors: relation to stress-induced sensitization. J Pharmacol Exp Ther (2009) 1.20

The role of progestins in the behavioral effects of cocaine and other drugs of abuse: human and animal research. Neurosci Biobehav Rev (2010) 1.16

Exogenous cortisol acutely influences motivated decision making in healthy young men. Psychopharmacology (Berl) (2009) 1.16

Role of corticotropin-releasing factor in drug addiction: potential for pharmacological intervention. CNS Drugs (2011) 1.15

Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans. Biol Psychiatry (2013) 1.14

Banishing the Control Homunculi in Studies of Action Control and Behavior Change. Perspect Psychol Sci (2014) 1.12

Clonidine blocks stress-induced craving in cocaine users. Psychopharmacology (Berl) (2011) 1.12

Resilience in the Context of Chronic Stress and Health in Adults. Soc Personal Psychol Compass (2011) 1.11

Sex differences in the effects of allopregnanolone on yohimbine-induced reinstatement of cocaine seeking in rats. Drug Alcohol Depend (2009) 1.11

Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption. Alcohol Res (2012) 1.10

Biological mechanisms underlying the relationship between stress and smoking: state of the science and directions for future work. Biol Psychol (2011) 1.09

New findings on biological factors predicting addiction relapse vulnerability. Curr Psychiatry Rep (2011) 1.09

Reconsolidation of drug memories. Neurosci Biobehav Rev (2012) 1.08

Alcohol stress response dampening: selective reduction of anxiety in the face of uncertain threat. J Psychopharmacol (2011) 1.07

Pharmacotherapy of PTSD: premises, principles, and priorities. Brain Res (2009) 1.07

Effects of acute psychosocial stress on cigarette craving and smoking. Nicotine Tob Res (2010) 1.06

β-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Biol Psychiatry (2011) 1.05

Should Hypersexual Disorder be Classified as an Addiction? Sex Addict Compulsivity (2013) 1.05

Brief meditation training induces smoking reduction. Proc Natl Acad Sci U S A (2013) 1.05

Neonatal maternal separation exacerbates the reward-enhancing effect of acute amphetamine administration and the anhedonic effect of repeated social defeat in adult rats. Neuroscience (2010) 1.04

Gene profiling reveals a role for stress hormones in the molecular and behavioral response to food restriction. Biol Psychiatry (2012) 1.04

Positive affective vocalizations during cocaine and sucrose self-administration: a model for spontaneous drug desire in rats. Neuropharmacology (2011) 1.03

Stress and alcohol: epidemiologic evidence. Alcohol Res (2012) 1.03

Two modes of intense cocaine bingeing: increased persistence after social defeat stress and increased rate of intake due to extended access conditions in rats. Psychopharmacology (Berl) (2009) 1.02

Sex differences in behavioral and neural cross-sensitization and escalated cocaine taking as a result of episodic social defeat stress in rats. Psychopharmacology (Berl) (2012) 1.02

Psychosocial stress and cigarette smoking persistence, cessation, and relapse over 9-10 years: a prospective study of middle-aged adults in the United States. Cancer Causes Control (2013) 1.02

Predictors of motivation for abstinence at the end of outpatient substance abuse treatment. J Subst Abuse Treat (2010) 1.02

Stressing zebrafish for behavioral genetics. Rev Neurosci (2011) 1.02

Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology (2010) 1.01

Sex differences in salivary cortisol in response to acute stressors among healthy participants, in recreational or pathological gamblers, and in those with posttraumatic stress disorder. Horm Behav (2009) 1.01

Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans. Neuropsychopharmacology (2012) 1.00

Stress and addiction: a dynamic interplay of genes, environment, and drug intake. Biol Psychiatry (2009) 1.00

The clinical neurobiology of drug craving. Curr Opin Neurobiol (2013) 0.99

Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice. Psychopharmacology (Berl) (2012) 0.99

Stress and VTA synapses: implications for addiction and depression. Eur J Neurosci (2014) 0.99

How does stress lead to risk of alcohol relapse? Alcohol Res (2012) 0.98

Stress modulates reinforcement learning in younger and older adults. Psychol Aging (2012) 0.98

Effects of cumulative stress and impulsivity on smoking status. Hum Psychopharmacol (2012) 0.98

Emotional valence and context of social influences on drug abuse-related behavior in animal models of social stress and prosocial interaction. Psychopharmacology (Berl) (2012) 0.97

Sex differences in decreased limbic and cortical grey matter volume in cocaine dependence: a voxel-based morphometric study. Addict Biol (2012) 0.96

Interactive effects of cumulative stress and impulsivity on alcohol consumption. Alcohol Clin Exp Res (2010) 0.96

Adult hippocampal neurogenesis in the pathogenesis of addiction and dual diagnosis disorders. Drug Alcohol Depend (2012) 0.96

Characteristics of emerging adulthood and e-cigarette use: Findings from a pilot study. Addict Behav (2015) 0.96

Early-Life Stress, HPA Axis Adaptation, and Mechanisms Contributing to Later Health Outcomes. Front Endocrinol (Lausanne) (2014) 0.95

Social subordination impairs hypothalamic-pituitary-adrenal function in female rhesus monkeys. Horm Behav (2012) 0.95

In vivo ethanol experience increases D(2) autoinhibition in the ventral tegmental area. Neuropsychopharmacology (2011) 0.95

Alcohol stress response dampening during imminent versus distal, uncertain threat. J Abnorm Psychol (2013) 0.95

BDNF overexpression in the ventral tegmental area prolongs social defeat stress-induced cross-sensitization to amphetamine and increases ΔFosB expression in mesocorticolimbic regions of rats. Neuropsychopharmacology (2013) 0.94

Nothing to fear? Neural systems supporting avoidance behavior in healthy youths. Neuroimage (2010) 0.94

A transdiagnostic minority stress treatment approach for gay and bisexual men's syndemic health conditions. Arch Sex Behav (2015) 0.93

The Relationship Between the Accumulated Number of Role Transitions and Hard Drug Use among Hispanic Emerging Adults. J Psychoactive Drugs (2015) 0.93

Activation of physiological stress responses by a natural reward: Novel vs. repeated sucrose intake. Physiol Behav (2015) 0.93

The limbic-hypothalamic-pituitary-adrenal axis and the development of alcohol use disorders in youth. Alcohol Clin Exp Res (2011) 0.93

Perceived discrimination among African American adolescents and allostatic load: a longitudinal analysis with buffering effects. Child Dev (2014) 0.93

Human laboratory paradigms in alcohol research. Alcohol Clin Exp Res (2012) 0.92

Coping and emotion regulation profiles as predictors of nonmedical prescription drug and illicit drug use among high-risk young adults. Drug Alcohol Depend (2013) 0.92

Preclinical evidence implicating corticotropin-releasing factor signaling in ethanol consumption and neuroadaptation. Genes Brain Behav (2015) 0.92

Neural correlates of stress and favorite-food cue exposure in adolescents: a functional magnetic resonance imaging study. Hum Brain Mapp (2012) 0.92

The effect of adverse rearing environments on persistent memories in young rats: removing the brakes on infant fear memories. Transl Psychiatry (2012) 0.91

Biological contributions to addictions in adolescents and adults: prevention, treatment, and policy implications. J Adolesc Health (2013) 0.91

A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation. J Psychopharmacol (2014) 0.91

Optogenetic strategies to investigate neural circuitry engaged by stress. Behav Brain Res (2013) 0.91

Reinstatement in a cocaine versus food choice situation: reversal of preference between drug and non-drug rewards. Addict Biol (2013) 0.90

Hazardous drinking and dimensions of impulsivity, behavioral approach, and inhibition in adult men and women. Alcohol Clin Exp Res (2012) 0.90

Neuroimaging mechanisms of change in psychotherapy for addictive behaviors: emerging translational approaches that bridge biology and behavior. Psychol Addict Behav (2013) 0.90

The role of guanfacine as a therapeutic agent to address stress-related pathophysiology in cocaine-dependent individuals. Adv Pharmacol (2014) 0.90

Is the rodent maternal separation model a valid and effective model for studies on the early-life impact on ethanol consumption? Psychopharmacology (Berl) (2013) 0.90

Pharmacological treatment of comorbid PTSD and substance use disorder: recent progress. Addict Behav (2013) 0.89

The Effect of Acute and Chronic Social Stress on the Hippocampal Transcriptome in Mice. PLoS One (2015) 0.89

Body mass index, metabolic factors, and striatal activation during stressful and neutral-relaxing states: an FMRI study. Neuropsychopharmacology (2010) 0.89

Variations in risk and protective factors for life satisfaction and mental wellbeing with deprivation: a cross-sectional study. BMC Public Health (2012) 0.89

Inter-individual diversity and intra-individual stability of amphetamine-induced sensitization of frequency-modulated 50-kHz vocalization in Sprague-Dawley rats. Psychopharmacology (Berl) (2012) 0.88

Noradrenergic synaptic function in the bed nucleus of the stria terminalis varies in animal models of anxiety and addiction. Neuropsychopharmacology (2013) 0.88

Risk-taking and decision-making in youth: relationships to addiction vulnerability. J Behav Addict (2013) 0.88

Cumulative adversity sensitizes neural response to acute stress: association with health symptoms. Neuropsychopharmacology (2013) 0.88

Self-reported impulsivity, but not behavioral choice or response impulsivity, partially mediates the effect of stress on drinking behavior. Stress (2012) 0.88

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61

The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev (1993) 19.60

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci (2005) 16.18

Role of genotype in the cycle of violence in maltreated children. Science (2002) 13.50

Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull (1997) 13.33

The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry (2005) 12.53

Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Brain Res Rev (1998) 12.19

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci U S A (1988) 11.96

Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev (2007) 11.15

The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry (2003) 10.60

The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl) (2002) 9.90

Addiction motivation reformulated: an affective processing model of negative reinforcement. Psychol Rev (2004) 9.30

Delay of gratification in children. Science (1989) 8.83

Drug abuse: hedonic homeostatic dysregulation. Science (1997) 8.22

Self-regulation and depletion of limited resources: does self-control resemble a muscle? Psychol Bull (2000) 7.88

Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med (2002) 7.72

Stress and depression. Annu Rev Clin Psychol (2005) 7.01

Addiction. Annu Rev Psychol (2002) 6.70

Limbic activation during cue-induced cocaine craving. Am J Psychiatry (1999) 6.66

Stress and hippocampal plasticity. Annu Rev Neurosci (1999) 6.31

Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons. Neuron (2003) 6.19

The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. Am J Psychiatry (1985) 6.16

Synaptic plasticity and addiction. Nat Rev Neurosci (2007) 6.08

How does stress increase risk of drug abuse and relapse? Psychopharmacology (Berl) (2001) 6.00

Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J Neurosci (2006) 5.69

Is there a common molecular pathway for addiction? Nat Neurosci (2005) 5.43

The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization. Am J Orthopsychiatry (1996) 4.93

Acute effects of cocaine on human brain activity and emotion. Neuron (1997) 4.88

Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biol Psychiatry (2005) 4.84

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nat Neurosci (2005) 4.83

Anticraving medications for relapse prevention: a possible new class of psychoactive medications. Am J Psychiatry (2005) 4.80

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev (1999) 4.77

Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cereb Cortex (2000) 4.61

Addiction and the brain: the neurobiology of compulsion and its persistence. Nat Rev Neurosci (2001) 4.58

The smoking problem: a review of the research and theory in behavioral risk modification. Psychol Bull (1980) 4.48

The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction (2000) 4.48

Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A (2004) 4.42

Stress, dysregulation of drug reward pathways, and the transition to drug dependence. Am J Psychiatry (2007) 4.37

Characteristics of children of alcoholics: putative risk factors, substance use and abuse, and psychopathology. J Abnorm Psychol (1991) 4.37

Plasticity of reward neurocircuitry and the 'dark side' of drug addiction. Nat Neurosci (2005) 4.36

Activation of memory circuits during cue-elicited cocaine craving. Proc Natl Acad Sci U S A (1996) 4.31

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Brain Res Mol Brain Res (1993) 4.13

Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse (1993) 4.13

Childhood abuse and lifetime psychopathology in a community sample. Am J Psychiatry (2001) 4.07

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res Brain Res Rev (1992) 4.03

Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am J Psychiatry (2005) 4.01

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry (2006) 3.97

Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J Neurosci (2006) 3.96

Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nat Neurosci (2002) 3.89

Neural activity related to drug craving in cocaine addiction. Arch Gen Psychiatry (2001) 3.84

A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Res Brain Res Rev (1997) 3.80

Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature (1997) 3.76

Endocrinology of the stress response. Annu Rev Physiol (2005) 3.74

Conditioning factors in drug abuse: can they explain compulsion? J Psychopharmacol (1998) 3.65

The measurement of drug craving. Addiction (2000) 3.64

Early onset cannabis use and psychosocial adjustment in young adults. Addiction (1997) 3.60

Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes. Arch Gen Psychiatry (2006) 3.55

Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Neurosci (1999) 3.54

Dopamine and drug addiction: the nucleus accumbens shell connection. Neuropharmacology (2004) 3.52

Executive dysfunction in cocaine addiction: evidence for discordant frontal, cingulate, and cerebellar activity. J Neurosci (2004) 3.27

Posttraumatic stress disorder and the incidence of nicotine, alcohol, and other drug disorders in persons who have experienced trauma. Arch Gen Psychiatry (2003) 3.17

The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse? Neurosci Biobehav Rev (2005) 3.17

PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys. Nat Neurosci (2006) 3.13

Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. Biol Psychiatry (2005) 3.04

Neural activation patterns of methamphetamine-dependent subjects during decision making predict relapse. Arch Gen Psychiatry (2005) 3.03

Psychological stress, drug-related cues and cocaine craving. Psychopharmacology (Berl) (2000) 3.00

Incubation of cocaine craving after withdrawal: a review of preclinical data. Neuropharmacology (2004) 2.99

Direct activation of the ventral striatum in anticipation of aversive stimuli. Neuron (2003) 2.99

Neurobiological mechanisms in the transition from drug use to drug dependence. Neurosci Biobehav Rev (2004) 2.97

Cingulate hypoactivity in cocaine users during a GO-NOGO task as revealed by event-related functional magnetic resonance imaging. J Neurosci (2003) 2.96

Drug dependence: stress and dysregulation of brain reward pathways. Drug Alcohol Depend (1998) 2.94

Dopamine release in response to a psychological stress in humans and its relationship to early life maternal care: a positron emission tomography study using [11C]raclopride. J Neurosci (2004) 2.93

Child maltreatment. Annu Rev Clin Psychol (2005) 2.92

Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. Am J Psychiatry (2007) 2.90

The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis. Neuropsychopharmacology (2004) 2.87

Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. Am J Psychiatry (2004) 2.84

Lifetime traumas and mental health: the significance of cumulative adversity. J Health Soc Behav (1995) 2.83

Concomitance between childhood sexual and physical abuse and substance use problems. A review. Clin Psychol Rev (2002) 2.81

Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. Neuron (2003) 2.81

Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. J Neurosci (2005) 2.76

Endocannabinoid control of food intake and energy balance. Nat Neurosci (2005) 2.74

Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biol Psychiatry (2001) 2.70

Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl) (2004) 2.69

The dopamine hypothesis of reward: past and current status. Trends Neurosci (1999) 2.68

Motivational influences on cigarette smoking. Annu Rev Psychol (2004) 2.61

Emotional distress regulation takes precedence over impulse control: if you feel bad, do it! J Pers Soc Psychol (2001) 2.58

Drug addiction: the neurobiology of disrupted self-control. Trends Mol Med (2006) 2.57

Reward circuitry activation by noxious thermal stimuli. Neuron (2001) 2.56

Imaging stress- and cue-induced drug and alcohol craving: association with relapse and clinical implications. Drug Alcohol Rev (2007) 2.56

Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J Neurobiol (2001) 2.50

Trajectories of marijuana use from adolescence to young adulthood: predictors and outcomes. Dev Psychopathol (2004) 2.49

Neurobiology of craving, conditioned reward and relapse. Curr Opin Pharmacol (2005) 2.47

Impact of adolescent drug use and social support on problems of young adults: a longitudinal study. J Abnorm Psychol (1988) 2.46

Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biol Psychiatry (2005) 2.45

Long-term behavioral and neuroendocrine adaptations to adverse early experience. Prog Brain Res (2000) 2.45

Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons. Annu Rev Pharmacol Toxicol (1996) 2.43

Coping dimensions, life stress, and adolescent substance use: a latent growth analysis. J Abnorm Psychol (2001) 2.41

The neural correlates of cue-induced craving in cocaine-dependent women. Am J Psychiatry (2004) 2.34

Developmental determinants of sensitivity and resistance to stress. Psychoneuroendocrinology (2005) 2.29