Published in J Clin Invest on February 01, 1991
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med (1996) 6.36
The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol (1992) 3.21
Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduodenal mucosa. J Clin Pathol (1994) 3.16
Macrophage inflammatory protein-1 alpha. A novel chemotactic cytokine for macrophages in rheumatoid arthritis. J Clin Invest (1994) 2.15
Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol (1994) 2.04
Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis. J Clin Invest (1995) 1.76
Long-term impaired neutrophil migration in mice overexpressing human interleukin-8. J Clin Invest (1994) 1.51
Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis. Gut (2002) 1.45
Localized expression of mRNA for phagocyte-specific chemotactic cytokines in human periodontal infections. Infect Immun (1994) 1.39
Interleukin 8: cells of origin in inflammatory bowel disease. Gut (1996) 1.35
Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis. Gut (1993) 1.33
Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis. J Exp Med (1997) 1.31
Roles of proinflammatory and anti-inflammatory cytokines in pathophysiology of bacterial meningitis and effect of adjunctive therapy. Infect Immun (1996) 1.19
Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion. Eur J Immunol (2009) 1.11
Interferon-gamma inhibits interleukin-8 production by human polymorphonuclear leucocytes. Immunology (1993) 1.09
Polarised interleukin 8 secretion by HT 29/19A cells. Gut (1994) 1.08
Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis. J Clin Invest (1992) 1.04
Interleukin-8 primes human neutrophils for enhanced superoxide anion production. Immunology (1993) 1.02
CXCR2: From Bench to Bedside. Front Immunol (2012) 1.01
IL-8 as a circulating cytokine: induction by recombinant tumour necrosis factor-alpha. Clin Exp Immunol (1992) 0.99
Differential normalization of mucosal interleukin-8 and interleukin-6 activity after Helicobacter pylori eradication. Infect Immun (1998) 0.97
Kinetics of cytokine secretion by mononuclear cells of the blood from rheumatoid arthritis patients are different from those of healthy controls. Clin Exp Immunol (1992) 0.96
Flare-up of experimental arthritis in mice with murine recombinant IL-1. Clin Exp Immunol (1992) 0.96
Progress toward the total synthesis of frondosin C. Org Lett (2006) 0.96
Anti-inflammatory mechanism of tocilizumab, a humanized anti-IL-6R antibody: effect on the expression of chemokine and adhesion molecule. Rheumatol Int (2009) 0.95
Surface expression of CC- and CXC-chemokine receptors on leucocyte subsets in inflammatory joint diseases. Clin Exp Immunol (2001) 0.95
Anti-CagA immunoglobulin G responses correlate with interleukin-8 induction in human gastric mucosal biopsy culture. Clin Diagn Lab Immunol (2000) 0.93
The organocatalytic three-step total synthesis of (+)-frondosin B. Chem Sci (2010) 0.90
Neutrophil chemotactic factors produced by malignant fibrous histiocytoma cell lines. Br J Cancer (1993) 0.86
Beta 2 (CD18) and beta 1 (CD29) integrin mechanisms in migration of human polymorphonuclear leucocytes and monocytes through lung fibroblast barriers: shared and distinct mechanisms. Immunology (1997) 0.85
Glucocorticoids as cytokine inhibitors: role in neuroendocrine control and therapy of inflammatory diseases. Mediators Inflamm (1993) 0.85
Chemokines and angiogenesis in rheumatoid arthritis. Front Biosci (Elite Ed) (2009) 0.84
Synthesis of cycloheptanoid natural products via tandem 5-exo cyclization/Claisen rearrangement process. ARKIVOC (2010) 0.82
Dexamethasone prevents autoimmune nephritis and reduces renal expression of Ia but not costimulatory signals. Am J Pathol (1992) 0.82
Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes. MAbs (2014) 0.82
Pharmacogenetics of chronic pain and its treatment. Mediators Inflamm (2013) 0.81
The effect of infliximab on chemokines in patients with rheumatoid arthritis. Clin Rheumatol (2006) 0.79
Interleukin-8 in Hodgkin's disease. Preferential expression by reactive cells and association with neutrophil density. Am J Pathol (1996) 0.77
Immunohistochemical studies on NAP-1/IL-8 in contact eczema and atopic dermatitis. Arch Dermatol Res (1992) 0.77
Phytochemical composition and anti-inflammatory activity of extracts from the whole-meal flour of Italian durum wheat cultivars. Int J Mol Sci (2015) 0.77
Hyperalgesia and edema responses induced by rat peripheral blood mononuclear cells incubated with carrageenin. Inflammation (2001) 0.77
Gene Expression Deconvolution for Uncovering Molecular Signatures in Response to Therapy in Juvenile Idiopathic Arthritis. PLoS One (2016) 0.75
A factor released by monocytes in the presence of dexamethasone stimulates neutrophil locomotion. Br J Pharmacol (1993) 0.75
H-2g, a glucose analog of blood group H antigen, mediates monocyte recruitment in vitro and in vivo via IL-8/CXCL8. Open Access Rheumatol (2012) 0.75
Piperine Suppresses the Expression of CXCL8 in Lipopolysaccharide-Activated SW480 and HT-29 Cells via Downregulating the Mitogen-Activated Protein Kinase Pathways. Inflammation (2015) 0.75
ERK2 and JNK1 contribute to TNF-α-induced IL-8 expression in synovial fibroblasts. PLoS One (2017) 0.75
Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene. Sci Rep (2017) 0.75
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum (1988) 111.05
Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest (1989) 10.59
Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature (1980) 9.25
Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest (1985) 8.70
Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab Invest (1987) 7.95
Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors. J Immunol (1985) 7.20
Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol (1976) 7.06
Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines. Proc Natl Acad Sci U S A (1987) 6.90
Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions. J Immunol (1978) 6.04
An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism. J Immunol (1986) 5.14
A novel neutrophil-activating factor produced by human mononuclear phagocytes. J Exp Med (1988) 4.86
In vitro synthesis of immunoglobulin by rheumatoid synovial membrane. J Clin Invest (1968) 4.01
Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes. Biochem Biophys Res Commun (1987) 3.77
Synthesis and expression in Escherichia coli of the gene encoding monocyte-derived neutrophil-activating factor: biological equivalence between natural and recombinant neutrophil-activating factor. Proc Natl Acad Sci U S A (1988) 3.37
Immunglobulin classes, subclasses and complexes of IgG rheumatoid factor in rheumatoid plasma cells. Clin Exp Immunol (1972) 2.70
Monokine-induced neutrophil chemotactic factor gene expression in human fibroblasts. J Biol Chem (1989) 2.43
In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes. Am J Pathol (1989) 2.37
Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts. Scand J Immunol (1983) 2.10
Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP). Biochem Biophys Res Commun (1988) 2.10
Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. II. Low levels of synovial fluid and synovial tissue interferon suggest that gamma-interferon is not the primary macrophage activating factor. Arthritis Rheum (1987) 2.04
Secretion of novel and homologous neutrophil-activating peptides by LPS-stimulated human endothelial cells. J Immunol (1989) 2.04
Appearance of anti-HLA-DR-reactive cells in normal and rheumatoid synovial tissue. Scand J Immunol (1981) 2.02
Immunohistochemical studies of interleukin-2 and gamma-interferon in rheumatoid arthritis. Arthritis Rheum (1985) 1.62
In vitro and in vivo activation of human mononuclear phagocytes by interferon-gamma. Studies with normal and AIDS monocytes. J Immunol (1987) 1.51
Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor. Biochem Biophys Res Commun (1988) 1.46
Neutrophil accumulation and plasma leakage induced in vivo by neutrophil-activating peptide-1. J Leukoc Biol (1990) 1.33
IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. J Immunol (1988) 1.30
Elevation of PMN cytosolic free calcium and locomotion stimulated by novel peptides from IL-1-treated human synovial cell cultures. Biochem Biophys Res Commun (1988) 1.27
Characterization of blood mononuclear cells of rheumatoid arthritis patients. I. Depressed lymphocyte proliferation and enhanced prostanoid release from monocytes. Clin Immunol Immunopathol (1982) 1.18
Interleukin-1-like activities in synovial fluids of patients with rheumatoid arthritis and traumatic synovitis. Rheumatol Int (1985) 1.16
Inflammatory cytokines induce synthesis and secretion of gro protein and a neutrophil chemotactic factor but not beta 2-microglobulin in human synovial cells and fibroblasts. Biochem J (1989) 1.15
Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. I. A cytofluorographic study of monocyte differentiation antigens and class II antigens and their regulation by gamma-interferon. Arthritis Rheum (1987) 1.14
Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. Ann Rheum Dis (1985) 1.05
Cellular mechanisms of proteinase release from inflammatory cells and the degradation of extracellular proteins. Ciba Found Symp (1979) 1.05
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay. Biochem Pharmacol (1987) 1.05
Enhanced phospholipase activity in peripheral blood monocytes from patients with rheumatoid arthritis. Arthritis Rheum (1986) 1.03
Impaired mitogen-induced interferon-gamma production in rheumatoid arthritis and related diseases. Scand J Immunol (1988) 0.96
Reduced production of interferon alpha and interferon gamma in leukocyte cultures from patients with active rheumatoid arthritis. Scand J Rheumatol (1987) 0.92
Phagocytosis, bactericidal capacity, and PGE2 production of monocytes in systemic lupus erythematosus and rheumatoid arthritis. Diagn Immunol (1984) 0.83
Interleukin 1 activity produced by human rheumatoid and normal dendritic cells. Scand J Immunol (1986) 0.82
Uptake of fatty acids and their mobilization from phospholipids in cultured monocyte-macrophages from rheumatoid arthritis patients. Clin Immunol Immunopathol (1986) 0.80
Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines. Adv Immunol (1994) 11.21
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature (1996) 9.25
Human chemokines: an update. Annu Rev Immunol (1997) 8.43
International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev (2000) 7.17
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med (1996) 6.36
A novel neutrophil-activating factor produced by human mononuclear phagocytes. J Exp Med (1988) 4.86
Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation. J Cell Biol (1969) 4.36
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J (1997) 4.04
CCR5 is characteristic of Th1 lymphocytes. Nature (1998) 3.92
Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes. Biochem Biophys Res Commun (1987) 3.77
Biochemical and morphological characterization of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes. J Cell Biol (1974) 3.71
HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med (1997) 3.71
B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med (1998) 3.60
Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem (1994) 3.50
Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration. Nature (1987) 3.39
Synthesis and expression in Escherichia coli of the gene encoding monocyte-derived neutrophil-activating factor: biological equivalence between natural and recombinant neutrophil-activating factor. Proc Natl Acad Sci U S A (1988) 3.37
Association of lactoferrin with specific granules in rabbit heterophil leukocytes. J Exp Med (1970) 3.32
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med (1996) 3.30
Further biochemical and morphological studies of granule fractions from rabbit heterophil leukocytes. J Cell Biol (1970) 3.06
Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8. J Exp Med (1991) 2.96
Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J (1988) 2.83
Subcellular localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes. J Exp Med (1975) 2.64
HIV blocked by chemokine antagonist. Nature (1996) 2.50
Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. Eur J Immunol (1995) 2.48
Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. J Exp Med (1991) 2.46
Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci U S A (1993) 2.45
Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J Exp Med (1990) 2.42
In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes. Am J Pathol (1989) 2.37
Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33
Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J Exp Med (1978) 2.32
Neutrophil activation by monomeric interleukin-8. Science (1994) 2.31
Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med (1994) 2.29
Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes. FASEB J (1994) 2.27
Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol (1990) 2.25
The rate of decline of diphenylhydantoin in human plasma. Clin Pharmacol Ther (1970) 2.23
Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest (1982) 2.21
Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. Biochemistry (1991) 2.20
Neutrophil-activating properties of the melanoma growth-stimulatory activity. J Exp Med (1990) 2.17
Structure-activity relationships of chemokines. J Leukoc Biol (1995) 2.15
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur J Immunol (1998) 2.15
The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4. Eur J Immunol (1997) 2.14
The importance of measuring cotinine levels to identify smokers in clinical trials. Clin Pharmacol Ther (1994) 2.11
Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood (1991) 2.10
Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg. Proc Natl Acad Sci U S A (1993) 2.09
High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest (1997) 2.09
Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med (1996) 2.08
Activation of NK cells by CC chemokines. Chemotaxis, Ca2+ mobilization, and enzyme release. J Immunol (1996) 1.99
Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. J Exp Med (1989) 1.98
Human alveolar macrophage gene expression of interleukin-8 by tumor necrosis factor-alpha, lipopolysaccharide, and interleukin-1 beta. Am J Respir Cell Mol Biol (1990) 1.98
BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. J Clin Invest (1999) 1.94
Use of gallium to treat Paget's disease of bone: a pilot study. Lancet (1990) 1.93
The interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma activate human neutrophil and basophil leukocytes. J Biol Chem (1993) 1.92
The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3. J Biol Chem (2000) 1.86
Assay of H2O2 production by macrophages and neutrophils with homovanillic acid and horse-radish peroxidase. J Immunol Methods (1983) 1.85
Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. J Clin Invest (2001) 1.84
Neutrophil-activating peptide 2 and gro/melanoma growth-stimulatory activity interact with neutrophil-activating peptide 1/interleukin 8 receptors on human neutrophils. J Biol Chem (1991) 1.83
Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol (1986) 1.82
Role of phagocytosis in the activation of macrophages. J Exp Med (1978) 1.77
Cytochemical localization of acid phosphatase activity in granule fractions from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.74
A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils. Biochem Biophys Res Commun (1989) 1.71
Neutrophil signal transduction and activation of the respiratory burst. Physiol Rev (1993) 1.69
Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr Biol (1997) 1.68
Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens. Biochem J (1982) 1.66
Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol (1990) 1.65
The neutrophil-activating peptide NAF/NAP-1 induces histamine and leukotriene release by interleukin 3-primed basophils. J Exp Med (1989) 1.65
Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids. J Biol Chem (1994) 1.64
The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes. Biochem J (1980) 1.64
Two transduction sequences are necessary for neutrophil activation by receptor agonists. J Biol Chem (1988) 1.62
Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis. Am J Pathol (1999) 1.62
Metabolism of the human immunodeficiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome P4503A4/3A5: mechanism-based inactivation of cytochrome P4503A by ritonavir. Drug Metab Dispos (1998) 1.57
Collagenase is a component of the specific granules of human neutrophil leucocytes. Biochem J (1977) 1.55
Calcium fluxes and calcium buffering in human neutrophils. J Biol Chem (1986) 1.52
Chemiluminescence detection of H2O2 produced by human neutrophils during the respiratory burst. Anal Biochem (1987) 1.51
Medical histories may be unreliable in screening volunteers for clinical trials. Clin Pharmacol Ther (1996) 1.49
RANTES and related chemokines activate human basophil granulocytes through different G protein-coupled receptors. Eur J Immunol (1993) 1.46
Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. Biochem Biophys Res Commun (1989) 1.46
Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues. Exp Cell Res (1987) 1.45
High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils. Proc Natl Acad Sci U S A (1992) 1.45
Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med (1997) 1.43
The polymorphonuclear leukocyte. Agents Actions (1978) 1.43