A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils.

PubWeight™: 1.71‹?› | Rank: Top 3%

🔗 View Article (PMID 2522778)

Published in Biochem Biophys Res Commun on March 31, 1989

Authors

A Walz1, M Baggiolini

Author Affiliations

1: Theodor-Kocher-Institut, University of Bern, Switzerland.

Articles citing this

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest (1989) 10.59

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes. J Exp Med (1992) 3.25

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. J Exp Med (1992) 3.20

Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. J Exp Med (1991) 2.46

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. J Exp Med (1989) 1.98

Lipopolysaccharide-stimulated human monocytes secrete, apart from neutrophil-activating peptide 1/interleukin 8, a second neutrophil-activating protein. NH2-terminal amino acid sequence identity with melanoma growth stimulatory activity. J Exp Med (1990) 1.53

Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor. J Clin Invest (1997) 1.49

Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue. Mol Cell Biol (1990) 1.22

Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases. J Exp Med (1990) 1.16

Release of CXC-chemokines by human lung microvascular endothelial cells (LMVEC) compared with macrovascular umbilical vein endothelial cells. Clin Exp Immunol (1999) 1.14

Interferon-gamma (IFN-gamma) and macrophage inflammatory proteins (MIP)-1 and -2 are involved in the regulation of the T cell-dependent chronic peritoneal neutrophilia of mice infected with mycobacteria. Clin Exp Immunol (1992) 1.02

Monocyte-derived CXCL7 peptides in the marrow microenvironment. Blood (2006) 0.95

Relationship of one form of human histamine-releasing factor to connective tissue activating peptide-III. J Clin Invest (1990) 0.92

CXCL7-Mediated Stimulation of Lymphangiogenic Factors VEGF-C, VEGF-D in Human Breast Cancer Cells. J Oncol (2010) 0.91

G-protein activation by interleukin 8 and related cytokines in human neutrophil plasma membranes. Biochem J (1992) 0.82

Novel roles of osteopontin and CXC chemokine ligand 7 in the defence against mycobacterial infection. Clin Exp Immunol (2006) 0.81

Bovine ENA, a new monocyte-macrophage derived cytokine of the interleukin-8 family. Structure, function, and expression in acute pulmonary inflammation. Am J Pathol (1994) 0.80

Formation of neutrophil-activating peptide 2 from platelet-derived connective-tissue-activating peptide III by different tissue proteinases. Biochem J (1991) 0.79

Overexpression of chemokine ligand 7 is associated with the progression of canine transmissible venereal tumor. BMC Vet Res (2012) 0.75

Articles by these authors

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature (1996) 9.25

International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev (2000) 7.17

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med (1996) 6.36

A novel neutrophil-activating factor produced by human mononuclear phagocytes. J Exp Med (1988) 4.86

Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation. J Cell Biol (1969) 4.36

Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J (1997) 4.04

CCR5 is characteristic of Th1 lymphocytes. Nature (1998) 3.92

Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes. Biochem Biophys Res Commun (1987) 3.77

Biochemical and morphological characterization of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes. J Cell Biol (1974) 3.71

HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med (1997) 3.71

B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med (1998) 3.60

Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem (1994) 3.50

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration. Nature (1987) 3.39

Association of lactoferrin with specific granules in rabbit heterophil leukocytes. J Exp Med (1970) 3.32

Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med (1996) 3.30

Further biochemical and morphological studies of granule fractions from rabbit heterophil leukocytes. J Cell Biol (1970) 3.06

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8. J Exp Med (1991) 2.96

Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J (1988) 2.83

Subcellular localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes. J Exp Med (1975) 2.64

Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities. J Biol Chem (1991) 2.50

HIV blocked by chemokine antagonist. Nature (1996) 2.50

Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. Eur J Immunol (1995) 2.48

Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. J Exp Med (1991) 2.46

Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci U S A (1993) 2.45

Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J Exp Med (1990) 2.42

In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes. Am J Pathol (1989) 2.37

Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33

Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J Exp Med (1978) 2.32

Neutrophil activation by monomeric interleukin-8. Science (1994) 2.31

Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med (1994) 2.29

Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes. FASEB J (1994) 2.27

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol (1990) 2.25

Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest (1982) 2.21

Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. Biochemistry (1991) 2.20

Neutrophil-activating properties of the melanoma growth-stimulatory activity. J Exp Med (1990) 2.17

Structure-activity relationships of chemokines. J Leukoc Biol (1995) 2.15

The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur J Immunol (1998) 2.15

The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4. Eur J Immunol (1997) 2.14

Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood (1991) 2.10

Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg. Proc Natl Acad Sci U S A (1993) 2.09

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest (1997) 2.09

Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med (1996) 2.08

Enhanced production of neutrophil-activating peptide-1/interleukin-8 in rheumatoid arthritis. J Clin Invest (1991) 2.04

Activation of NK cells by CC chemokines. Chemotaxis, Ca2+ mobilization, and enzyme release. J Immunol (1996) 1.99

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. J Exp Med (1989) 1.98

Human alveolar macrophage gene expression of interleukin-8 by tumor necrosis factor-alpha, lipopolysaccharide, and interleukin-1 beta. Am J Respir Cell Mol Biol (1990) 1.98

BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. J Clin Invest (1999) 1.94

The interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma activate human neutrophil and basophil leukocytes. J Biol Chem (1993) 1.92

The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3. J Biol Chem (2000) 1.86

Assay of H2O2 production by macrophages and neutrophils with homovanillic acid and horse-radish peroxidase. J Immunol Methods (1983) 1.85

Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity. J Clin Invest (2001) 1.84

Neutrophil-activating peptide 2 and gro/melanoma growth-stimulatory activity interact with neutrophil-activating peptide 1/interleukin 8 receptors on human neutrophils. J Biol Chem (1991) 1.83

Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol (1986) 1.82

Role of phagocytosis in the activation of macrophages. J Exp Med (1978) 1.77

Cytochemical localization of acid phosphatase activity in granule fractions from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.74

Neutrophil signal transduction and activation of the respiratory burst. Physiol Rev (1993) 1.69

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr Biol (1997) 1.68

Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens. Biochem J (1982) 1.66

Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol (1990) 1.65

The neutrophil-activating peptide NAF/NAP-1 induces histamine and leukotriene release by interleukin 3-primed basophils. J Exp Med (1989) 1.65

Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids. J Biol Chem (1994) 1.64

The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes. Biochem J (1980) 1.64

IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucyl-phenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway. J Immunol (1992) 1.63

Two transduction sequences are necessary for neutrophil activation by receptor agonists. J Biol Chem (1988) 1.62

Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis. Am J Pathol (1999) 1.62

Collagenase is a component of the specific granules of human neutrophil leucocytes. Biochem J (1977) 1.55

Calcium fluxes and calcium buffering in human neutrophils. J Biol Chem (1986) 1.52

Chemiluminescence detection of H2O2 produced by human neutrophils during the respiratory burst. Anal Biochem (1987) 1.51

RANTES and related chemokines activate human basophil granulocytes through different G protein-coupled receptors. Eur J Immunol (1993) 1.46

Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. Biochem Biophys Res Commun (1989) 1.46

High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils. Proc Natl Acad Sci U S A (1992) 1.45

Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues. Exp Cell Res (1987) 1.45

Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med (1997) 1.43

The polymorphonuclear leukocyte. Agents Actions (1978) 1.43

Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines. Arthritis Rheum (2000) 1.41

Mature dendritic cells respond to SDF-1, but not to several beta-chemokines. Immunobiology (1998) 1.40

Interleukin-8 antagonists generated by N-terminal modification. J Biol Chem (1993) 1.38

Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes. Eur J Immunol (2001) 1.38

Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. J Exp Med (1996) 1.38

Stimulation of phagocytosis in bone marrow-derived mouse macrophages by bacterial lipopolysaccharide: correlation with biochemical and functional parameters. J Immunol (1984) 1.36

Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2. Proc Natl Acad Sci U S A (1996) 1.36

Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood (1992) 1.36

Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes. Eur J Immunol (2001) 1.36

Identification of CCR8, the receptor for the human CC chemokine I-309. J Biol Chem (1997) 1.35

Exocytosis by neutrophils. Contemp Top Immunobiol (1984) 1.34

[Ca2+]i changes and respiratory burst in human neutrophils and monocytes induced by NAP-1/interleukin-8, NAP-2, and gro/MGSA. J Leukoc Biol (1991) 1.34

Neutrophil accumulation and plasma leakage induced in vivo by neutrophil-activating peptide-1. J Leukoc Biol (1990) 1.33

Expression of transcripts for two interleukin 8 receptors in human phagocytes, lymphocytes and melanoma cells. Biochem J (1993) 1.32

Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3. FEBS Lett (1994) 1.31

Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1. Eur J Immunol (1997) 1.31

The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process. J Biol Chem (1987) 1.28

RANTES and MCP-3 antagonists bind multiple chemokine receptors. J Biol Chem (1996) 1.27

Differential effects of neutrophil-activating peptide 1/IL-8 and its homologues on leukocyte adhesion and phagocytosis. J Immunol (1991) 1.26

Association of the alkaline phosphatase of rabbit polymorphonuclear leukocytes with the membrane of the specific granules. J Cell Biol (1973) 1.25

Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood (2001) 1.25

Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. Blood (2000) 1.24

Methods for assessing exocytosis by neutrophil leukocytes. Methods Enzymol (1986) 1.24

Chemokines and their receptors in lymphocyte traffic and HIV infection. Adv Immunol (2000) 1.24