Published in Dev Cell on November 01, 2008
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (2011) 2.82
Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol (2009) 2.67
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science (2009) 2.12
Cellular plasticity within the pancreas--lessons learned from development. Dev Cell (2010) 1.58
Extensive genetic variation in somatic human tissues. Proc Natl Acad Sci U S A (2012) 1.56
New school in liver development: lessons from zebrafish. Hepatology (2009) 1.36
Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. Cell Stem Cell (2014) 1.30
Sox9b is a key regulator of pancreaticobiliary ductal system development. PLoS Genet (2012) 1.30
Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Dev Cell (2010) 1.16
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish. Proc Natl Acad Sci U S A (2009) 1.10
Patterning and plasticity in development of the respiratory lineage. Dev Dyn (2010) 1.05
Concise review: clinical programs of stem cell therapies for liver and pancreas. Stem Cells (2013) 1.03
Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development. Development (2011) 1.01
Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish. BMC Biol (2011) 0.98
Restriction of hepatic competence by Fgf signaling. Development (2011) 0.97
Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. Dev Cell (2012) 0.95
Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell (2014) 0.95
Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening. Stem Cell Res (2010) 0.94
Orchestrating liver development. Development (2015) 0.94
Pancreas cell fate. Birth Defects Res C Embryo Today (2009) 0.91
Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses. PLoS One (2011) 0.91
Molecular pathways controlling pancreas induction. Semin Cell Dev Biol (2012) 0.91
Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol (2013) 0.90
Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates. Semin Cell Dev Biol (2011) 0.88
Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc Natl Acad Sci U S A (2012) 0.88
The transcriptomics of glucocorticoid receptor signaling in developing zebrafish. PLoS One (2013) 0.87
Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence. Genes Dev (2013) 0.86
Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas. Mol Biol Cell (2012) 0.86
Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol (2012) 0.86
Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio. PLoS One (2013) 0.85
The origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomes. BMC Evol Biol (2009) 0.85
Zebrafish models of human liver development and disease. Compr Physiol (2013) 0.84
Cellular and molecular basis of liver development. Compr Physiol (2013) 0.84
EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality. Dev Cell (2016) 0.83
Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development (2013) 0.83
Vibratome sectioning for enhanced preservation of the cytoarchitecture of the mammalian organ of Corti. J Vis Exp (2011) 0.82
Wnt/β-catenin signaling cell-autonomously converts non-hepatic endodermal cells to a liver fate. Biol Open (2012) 0.80
Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development. Development (2011) 0.80
Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biol (2015) 0.79
Laminin β1a controls distinct steps during the establishment of digestive organ laterality. Development (2013) 0.78
Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Dev Biol (2016) 0.78
Recent advances in pancreas development: from embryonic pathways to programming renewable sources of beta cells. F1000 Biol Rep (2010) 0.78
FGF signaling is required for anterior but not posterior specification of the murine liver bud. Dev Dyn (2014) 0.77
Chromatin "pre-pattern" and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm. Nucleus (2012) 0.77
The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration. Curr Opin Genet Dev (2015) 0.76
Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype. Mech Dev (2013) 0.76
Frogs as integrative models for understanding digestive organ development and evolution. Semin Cell Dev Biol (2016) 0.76
Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration. PLoS Genet (2016) 0.75
Id2a is required for hepatic outgrowth during liver development in zebrafish. Mech Dev (2015) 0.75
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (2002) 12.21
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development (1996) 9.58
Mesodermal Wnt2b signalling positively regulates liver specification. Nature (2006) 3.69
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev (2001) 3.04
BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol (2006) 3.02
A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development (2001) 2.85
A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula. Nature (2006) 2.42
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev (2006) 2.15
The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development (1997) 2.14
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Dev Biol (2003) 2.10
Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev Biol (1998) 2.10
Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Dev Biol (2001) 2.04
Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina. Development (2005) 2.00
Retinoic acid signaling restricts the cardiac progenitor pool. Science (2005) 1.95
Origin and development of the zebrafish endoderm. Development (1999) 1.94
Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues. Dev Biol (2005) 1.94
Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. Dev Genet (1998) 1.91
The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis. Dev Cell (2008) 1.77
Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation. Development (2001) 1.71
Transgenic zebrafish reveal stage-specific roles for Bmp signaling in ventral and posterior mesoderm development. Development (2005) 1.68
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (2007) 1.66
Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol (2007) 1.58
Multicolor whole-mount in situ hybridization. Methods Mol Biol (2000) 1.53
Conservation of BMP signaling in zebrafish mesoderm patterning. Mech Dev (1997) 1.46
From endoderm formation to liver and pancreas development in zebrafish. Mech Dev (2003) 1.45
The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development (2001) 1.44
Intra-endodermal interactions are required for pancreatic beta cell induction. Dev Cell (2008) 1.41
Sonic hedgehog is required early in pancreatic islet development. Dev Biol (2002) 1.31
Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol (2001) 1.28
Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo. Curr Biol (2001) 1.24
BMP signalling regulates anteroposterior endoderm patterning in zebrafish. Mech Dev (2002) 1.23
The Xenopus tadpole gut: fate maps and morphogenetic movements. Development (2000) 1.16
Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling. Dev Biol (2004) 1.05
Origin of the zebrafish endocrine and exocrine pancreas. Dev Dyn (2007) 1.05
Study of hepatocyte differentiation using embryonic stem cells. J Cell Biochem (2005) 1.01
dlx3b and dlx4b function in the development of Rohon-Beard sensory neurons and trigeminal placode in the zebrafish neurula. Dev Biol (2004) 0.99
The location of the pregut endoderm in the chick embryo at the primitive streak stage as determined by radioautographic mapping. Dev Biol (1971) 0.96
Immunocytochemistry as a tool for zebrafish developmental neurobiology. Methods Cell Sci (2003) 0.94
Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis (2001) 0.90
Vertebrate Smoothened functions at the primary cilium. Nature (2005) 9.24
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature (2010) 6.69
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
Selective plane illumination microscopy techniques in developmental biology. Development (2009) 5.07
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development (2005) 5.06
Haematopoietic stem cells derive directly from aortic endothelium during development. Nature (2010) 4.42
Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet (2002) 3.81
Mesodermal Wnt2b signalling positively regulates liver specification. Nature (2006) 3.69
Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies. Dev Dyn (2007) 3.44
The perivascular niche regulates breast tumour dormancy. Nat Cell Biol (2013) 3.36
Fibronectin regulates epithelial organization during myocardial migration in zebrafish. Dev Cell (2004) 3.34
Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat Rev Mol Cell Biol (2011) 3.25
Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM). Opt Lett (2007) 3.16
Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol (2007) 3.07
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature (2004) 2.95
Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. Science (2009) 2.82
Optogenetic control of cardiac function. Science (2010) 2.63
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell (2008) 2.60
Formation of the digestive system in zebrafish. I. Liver morphogenesis. Dev Biol (2003) 2.48
Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis. Nat Genet (2007) 2.47
Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev (2008) 2.44
A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula. Nature (2006) 2.42
Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Dev Biol (2005) 2.38
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (2005) 2.32
Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish. Development (2003) 2.22
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nat Genet (2007) 2.14
Zebrafish model for human long QT syndrome. Proc Natl Acad Sci U S A (2007) 2.13
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Dev Biol (2003) 2.10
Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol (2008) 2.08
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest (2009) 1.98
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A (2011) 1.92
Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling. Proc Natl Acad Sci U S A (2009) 1.90
Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. Nat Protoc (2008) 1.87
Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint. Development (2003) 1.84
microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A (2008) 1.80
In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature (2013) 1.79
High-speed imaging of developing heart valves reveals interplay of morphogenesis and function. Development (2008) 1.70
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors. Dev Cell (2007) 1.68
Transcriptional silencing and reactivation in transgenic zebrafish. Genetics (2009) 1.67
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (2007) 1.66
In vivo cell biology: following the zebrafish trend. Trends Cell Biol (2006) 1.66
A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Dev Biol (2007) 1.65
Hepatic stellate cells in liver development, regeneration, and cancer. J Clin Invest (2013) 1.64
A cellular framework for gut-looping morphogenesis in zebrafish. Science (2003) 1.63
A dual role for ErbB2 signaling in cardiac trabeculation. Development (2010) 1.59
Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biol (2004) 1.59
MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circ Res (2012) 1.56
Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors. Development (2012) 1.55
The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. Development (2002) 1.55
Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae. Biochemistry (2006) 1.51
Endothelial signals modulate hepatocyte apicobasal polarization in zebrafish. Curr Biol (2008) 1.49
The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Curr Biol (2008) 1.47
The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish. Development (2006) 1.46
From endoderm formation to liver and pancreas development in zebrafish. Mech Dev (2003) 1.45
Adenosine signaling promotes regeneration of pancreatic β cells in vivo. Cell Metab (2012) 1.45
Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. PLoS Genet (2007) 1.43
Intra-endodermal interactions are required for pancreatic beta cell induction. Dev Cell (2008) 1.41
Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol (2009) 1.40
The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr Biol (2009) 1.39
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nat Chem Biol (2012) 1.39
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development (2011) 1.31
Sox9b is a key regulator of pancreaticobiliary ductal system development. PLoS Genet (2012) 1.30
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes Dev (2008) 1.26
A mutation in zebrafish hmgcr1b reveals a role for isoprenoids in vertebrate heart-tube formation. Curr Biol (2007) 1.24
Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circ Res (2009) 1.23
Vegfc is required for vascular development and endoderm morphogenesis in zebrafish. EMBO Rep (2004) 1.21
Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis. Cell (2013) 1.21
Tbx5 and Bmp signaling are essential for proepicardium specification in zebrafish. Circ Res (2010) 1.21
Cardiac conduction is required to preserve cardiac chamber morphology. Proc Natl Acad Sci U S A (2010) 1.17
ETS factors regulate Vegf-dependent arterial specification. Dev Cell (2013) 1.16
Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Dev Cell (2010) 1.16
Hand2 regulates epithelial formation during myocardial diferentiation. Curr Biol (2005) 1.12
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish. Proc Natl Acad Sci U S A (2009) 1.10
Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens. Dev Biol (2010) 1.08
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. Gen Comp Endocrinol (2010) 1.07
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology (2008) 1.07
Multiple roles for Med12 in vertebrate endoderm development. Dev Biol (2008) 1.06
Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Dev Dyn (2005) 1.04
Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Dev Biol (2011) 1.02
A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. Genes Dev (2012) 1.02
Regulation of neurocoel morphogenesis by Pard6 gamma b. Dev Biol (2008) 1.01
Zebrafish in the study of early cardiac development. Circ Res (2012) 1.01
High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development (2014) 0.99
A window to the heart: can zebrafish mutants help us understand heart disease in humans? Trends Genet (2002) 0.99
Restriction of hepatic competence by Fgf signaling. Development (2011) 0.97
Cse1l is a negative regulator of CFTR-dependent fluid secretion. Curr Biol (2010) 0.96
Metabolic regulation of cellular plasticity in the pancreas. Curr Biol (2013) 0.96
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. J Cell Biol (2012) 0.95
Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS Genet (2013) 0.94
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Dis Model Mech (2010) 0.93
Suppression of Ptf1a activity induces acinar-to-endocrine conversion. Curr Biol (2011) 0.92
Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. Dev Biol (2011) 0.91
Antagonistic interaction between Wnt and Notch activity modulates the regenerative capacity of a zebrafish fibrotic liver model. Hepatology (2014) 0.90
3D imaging of transition metals in the zebrafish embryo by X-ray fluorescence microtomography. Metallomics (2014) 0.90
Notch signaling can regulate endoderm formation in zebrafish. Dev Dyn (2004) 0.90
Intrinsic and extrinsic modifiers of the regulative capacity of the developing liver. Mech Dev (2012) 0.90