|
1
|
Influence of controllable lifestyle on recent trends in specialty choice by US medical students.
|
JAMA
|
2003
|
14.06
|
|
2
|
Detection of microRNA expression in human peripheral blood microvesicles.
|
PLoS One
|
2008
|
8.04
|
|
3
|
The influence of controllable lifestyle and sex on the specialty choices of graduating U.S. medical students, 1996-2003.
|
Acad Med
|
2005
|
3.32
|
|
4
|
Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia.
|
J Clin Oncol
|
2008
|
2.79
|
|
5
|
Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway.
|
Blood
|
2009
|
2.39
|
|
6
|
Administrative coding data, compared with CDC/NHSN criteria, are poor indicators of health care-associated infections.
|
Am J Infect Control
|
2008
|
2.38
|
|
7
|
Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia.
|
Blood
|
2008
|
2.22
|
|
8
|
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.
|
Blood
|
2010
|
2.07
|
|
9
|
Discovery of anticancer agents of diverse natural origin.
|
Pure Appl Chem
|
2009
|
2.00
|
|
10
|
IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro.
|
Blood
|
2008
|
1.86
|
|
11
|
The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo.
|
Blood
|
2009
|
1.83
|
|
12
|
A comparison of normalization techniques for microRNA microarray data.
|
Stat Appl Genet Mol Biol
|
2008
|
1.82
|
|
13
|
FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma.
|
Blood
|
2007
|
1.69
|
|
14
|
In-hospital treatment of obstructive sleep apnea during decompensation of heart failure.
|
Chest
|
2009
|
1.63
|
|
15
|
Tetraspanin CD37 directly mediates transduction of survival and apoptotic signals.
|
Cancer Cell
|
2012
|
1.52
|
|
16
|
Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical.
|
Blood
|
2007
|
1.51
|
|
17
|
One-day quadruple therapy compared with 7-day triple therapy for Helicobacter pylori infection.
|
Arch Intern Med
|
2003
|
1.51
|
|
18
|
Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity.
|
Cancer Res
|
2006
|
1.45
|
|
19
|
Transtheoretical model-chronic disease care for obesity in primary care: a randomized trial.
|
Obes Res
|
2005
|
1.38
|
|
20
|
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody.
|
Blood
|
2009
|
1.25
|
|
21
|
IL-12 enhances the antitumor actions of trastuzumab via NK cell IFN-γ production.
|
J Immunol
|
2011
|
1.25
|
|
22
|
Piwil2 is expressed in various stages of breast cancers and has the potential to be used as a novel biomarker.
|
Int J Clin Exp Pathol
|
2010
|
1.24
|
|
23
|
Predicting control of primary tumor and survival by DCE MRI during early therapy in cervical cancer.
|
Invest Radiol
|
2009
|
1.24
|
|
24
|
Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
|
Circulation
|
2008
|
1.23
|
|
25
|
The relationship between body mass index and thyroid cancer pathology features and outcomes: a clinicopathological cohort study.
|
J Clin Endocrinol Metab
|
2010
|
1.22
|
|
26
|
Effectiveness of a postdischarge care management model for stroke and transient ischemic attack: a randomized trial.
|
J Stroke Cerebrovasc Dis
|
2007
|
1.20
|
|
27
|
Effectiveness of a group exercise program in a long-term care facility: a randomized pilot trial.
|
J Am Med Dir Assoc
|
2003
|
1.20
|
|
28
|
Comparative assessment of clinically utilized CD20-directed antibodies in chronic lymphocytic leukemia cells reveals divergent NK cell, monocyte, and macrophage properties.
|
J Immunol
|
2013
|
1.18
|
|
29
|
A novel Raji-Burkitt's lymphoma model for preclinical and mechanistic evaluation of CD52-targeted immunotherapeutic agents.
|
Clin Cancer Res
|
2008
|
1.17
|
|
30
|
Prevalence of exercise-induced bronchospasm in a cohort of varsity college athletes.
|
Med Sci Sports Exerc
|
2007
|
1.15
|
|
31
|
Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias.
|
Blood
|
2012
|
1.13
|
|
32
|
Piwil2 expressed in various stages of cervical neoplasia is a potential complementary marker for p16.
|
Am J Transl Res
|
2010
|
1.13
|
|
33
|
FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus.
|
J Immunol
|
2009
|
1.11
|
|
34
|
Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents.
|
ACS Med Chem Lett
|
2012
|
1.11
|
|
35
|
Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells.
|
AAPS J
|
2011
|
1.11
|
|
36
|
The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo.
|
PLoS One
|
2010
|
1.11
|
|
37
|
Assessing dietary and exercise stage of change to optimize weight loss interventions.
|
Obes Res
|
2003
|
1.09
|
|
38
|
Workplace based mindfulness practice and inflammation: a randomized trial.
|
Brain Behav Immun
|
2012
|
1.08
|
|
39
|
In-hospital testing for sleep-disordered breathing in hospitalized patients with decompensated heart failure: report of prevalence and patient characteristics.
|
J Card Fail
|
2009
|
1.07
|
|
40
|
Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate.
|
Cancer Genet
|
2011
|
1.06
|
|
41
|
Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol.
|
Clin Cancer Res
|
2012
|
1.04
|
|
42
|
Central sleep apnea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure.
|
J Card Fail
|
2012
|
1.02
|
|
43
|
The proteasome inhibitor carfilzomib functions independently of p53 to induce cytotoxicity and an atypical NF-κB response in chronic lymphocytic leukemia cells.
|
Clin Cancer Res
|
2013
|
0.99
|
|
44
|
Dose-dependency of massage-like compressive loading on recovery of active muscle properties following eccentric exercise: rabbit study with clinical relevance.
|
Br J Sports Med
|
2012
|
0.99
|
|
45
|
Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.
|
PLoS One
|
2010
|
0.99
|
|
46
|
CYP2D6 genotypes, endoxifen levels, and disease recurrence in 224 Filipino and Vietnamese women receiving adjuvant tamoxifen for operable breast cancer.
|
Springerplus
|
2013
|
0.99
|
|
47
|
Transcriptional control of human T-BET expression: the role of Sp1.
|
Eur J Immunol
|
2007
|
0.96
|
|
48
|
Modulation of sodium/iodide symporter expression in the salivary gland.
|
Thyroid
|
2013
|
0.96
|
|
49
|
Reciprocal regulation of activating and inhibitory Fc{gamma} receptors by TLR7/8 activation: implications for tumor immunotherapy.
|
Clin Cancer Res
|
2010
|
0.96
|
|
50
|
Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells.
|
Blood
|
2006
|
0.94
|
|
51
|
Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion.
|
Endocr Relat Cancer
|
2010
|
0.93
|
|
52
|
Survival after adjuvant oophorectomy and tamoxifen in operable breast cancer in premenopausal women.
|
J Clin Oncol
|
2007
|
0.93
|
|
53
|
Reliability of surgical skills scores in otolaryngology residents: analysis using generalizability theory.
|
Eval Health Prof
|
2008
|
0.93
|
|
54
|
Massage timing affects postexercise muscle recovery and inflammation in a rabbit model.
|
Med Sci Sports Exerc
|
2013
|
0.92
|
|
55
|
Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells.
|
Blood
|
2010
|
0.92
|
|
56
|
IgG is transported across the mouse yolk sac independently of FcgammaRIIb.
|
J Reprod Immunol
|
2009
|
0.92
|
|
57
|
Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer.
|
PLoS Med
|
2007
|
0.91
|
|
58
|
Thyroid-specific ablation of the Carney complex gene, PRKAR1A, results in hyperthyroidism and follicular thyroid cancer.
|
Endocr Relat Cancer
|
2012
|
0.90
|
|
59
|
Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia.
|
Blood
|
2012
|
0.90
|
|
60
|
Growth hormone injections improve bone quality in a mouse model of osteogenesis imperfecta.
|
J Bone Miner Res
|
2005
|
0.89
|
|
61
|
A scoring system for the prognosis and treatment of malignant bowel obstruction.
|
Surgery
|
2012
|
0.89
|
|
62
|
Fully moderated T-statistic for small sample size gene expression arrays.
|
Stat Appl Genet Mol Biol
|
2011
|
0.88
|
|
63
|
Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.
|
J Clin Endocrinol Metab
|
2014
|
0.88
|
|
64
|
Endothelial dysfunction in the microcirculation of patients with obstructive sleep apnea.
|
Am J Respir Crit Care Med
|
2010
|
0.87
|
|
65
|
Toll-like receptor 2 ligands regulate monocyte Fcγ receptor expression and function.
|
J Biol Chem
|
2013
|
0.87
|
|
66
|
Bone mineral density following surgical oophorectomy and tamoxifen adjuvant therapy for breast cancer.
|
Cancer
|
2013
|
0.86
|
|
67
|
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia.
|
Blood
|
2011
|
0.86
|
|
68
|
Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.
|
Leuk Res
|
2010
|
0.86
|
|
69
|
Milatuzumab-conjugated liposomes as targeted dexamethasone carriers for therapeutic delivery in CD74+ B-cell malignancies.
|
Clin Cancer Res
|
2012
|
0.86
|
|
70
|
Autoschizis: a new form of cell death for human ovarian carcinoma cells following ascorbate:menadione treatment. Nuclear and DNA degradation.
|
Tissue Cell
|
2004
|
0.84
|
|
71
|
Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.
|
Endocr Relat Cancer
|
2012
|
0.84
|
|
72
|
Epigenetic regulation of beta2-adrenergic receptor expression in T(H)1 and T(H)2 cells.
|
Brain Behav Immun
|
2010
|
0.84
|
|
73
|
The AD-LIFE trial: working to integrate medical and psychosocial care management models.
|
Home Healthc Nurse
|
2007
|
0.83
|
|
74
|
Differential effects of IL-2 and IL-21 on expansion of the CD4+ CD25+ Foxp3+ T regulatory cells with redundant roles in natural killer cell mediated antibody dependent cellular cytotoxicity in chronic lymphocytic leukemia.
|
MAbs
|
2010
|
0.83
|
|
75
|
Effects on survival of menstrual cycle phase of adjuvant surgical oophorectomy in premenopausal women with breast cancer.
|
Breast Cancer Res Treat
|
2011
|
0.83
|
|
76
|
Targeted drug delivery and cross-linking induced apoptosis with anti-CD37 based dual-ligand immunoliposomes in B chronic lymphocytic leukemia cells.
|
Biomaterials
|
2013
|
0.83
|
|
77
|
A randomized trial testing the superiority of a postdischarge care management model for stroke survivors.
|
J Stroke Cerebrovasc Dis
|
2009
|
0.82
|
|
78
|
Glycovariant anti-CD37 monospecific protein therapeutic exhibits enhanced effector cell-mediated cytotoxicity against chronic and acute B cell malignancies.
|
MAbs
|
2013
|
0.82
|
|
79
|
Development of p21 activated kinase-targeted multikinase inhibitors that inhibit thyroid cancer cell migration.
|
J Clin Endocrinol Metab
|
2013
|
0.81
|
|
80
|
Cardiac effects of continuous and bilevel positive airway pressure for patients with heart failure and obstructive sleep apnea: a pilot study.
|
Chest
|
2008
|
0.81
|
|
81
|
LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.
|
PLoS One
|
2011
|
0.81
|
|
82
|
The after discharge care management of low income frail elderly (AD-LIFE) randomized trial: theoretical framework and study design.
|
Popul Health Manag
|
2011
|
0.80
|
|
83
|
Pharmacokinetics and tissue disposition of lenalidomide in mice.
|
AAPS J
|
2012
|
0.80
|
|
84
|
Use of the hollow fiber assay for the discovery of novel anticancer agents from fungi.
|
Methods Mol Biol
|
2012
|
0.79
|
|
85
|
OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway.
|
Br J Haematol
|
2011
|
0.78
|
|
86
|
Sample size re-estimation in a breast cancer trial.
|
Clin Trials
|
2010
|
0.78
|
|
87
|
Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma.
|
J Asthma
|
2008
|
0.76
|
|
88
|
Prevalence of obstructive sleep apnea in patients with chronic wounds.
|
J Clin Sleep Med
|
2010
|
0.75
|
|
89
|
Biopsychosocial characteristics of overweight and obese primary care patients: do psychosocial and behavior factors mediate sociodemographic effects?
|
Prev Med
|
2003
|
0.75
|
|
90
|
Nesiritide in acute decompensated heart failure: a pooled analysis of randomized controlled trials.
|
Clin Cardiol
|
2010
|
0.75
|