Inherited susceptibility to common cancers.

BRCA1 and BRCA2: different roles in a common pathway of genome protection. Nat Rev Cancer (2011) 3.85

A survey of tools for variant analysis of next-generation genome sequencing data. Brief Bioinform (2013) 3.60

New insights into the aetiology of colorectal cancer from genome-wide association studies. Nat Rev Genet (2009) 3.22

Susceptibility pathways in Fanconi's anemia and breast cancer. N Engl J Med (2010) 2.79

The molecular pathology of cancer. Nat Rev Clin Oncol (2010) 1.86

BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs. J Transl Med (2012) 1.76

Biomarkers in early-stage non-small-cell lung cancer: current concepts and future directions. J Thorac Oncol (2014) 1.56

Genetic architecture of cancer and other complex diseases: lessons learned and future directions. Carcinogenesis (2011) 1.39

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res (2010) 1.32

Germline DNA copy number variation in familial and early-onset breast cancer. Breast Cancer Res (2012) 1.24

Genetic testing for familial/hereditary breast cancer-comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany. J Community Genet (2011) 1.23

Bridging the gap between biologic, individual, and macroenvironmental factors in cancer: a multilevel approach. Cancer Epidemiol Biomarkers Prev (2013) 1.22

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice. J Clin Invest (2011) 1.20

Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer. Proc Natl Acad Sci U S A (2014) 1.12

BRCA1 is an essential regulator of heart function and survival following myocardial infarction. Nat Commun (2011) 1.11

Fragile X syndrome: the FMR1 CGG repeat distribution among world populations. Ann Hum Genet (2011) 1.08

Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery. Cell Cycle (2013) 1.07

Sun exposure causes somatic second-hit mutations and angiofibroma development in tuberous sclerosis complex. Hum Mol Genet (2013) 1.06

Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases. Breast Cancer Res (2012) 1.05

High frequency of BRCA1 founder mutations in Polish women with nonfamilial breast cancer. Fam Cancer (2012) 1.02

BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies. Cell Cycle (2012) 1.00

Hereditary breast cancer: ever more pieces to the polygenic puzzle. Hered Cancer Clin Pract (2013) 0.99

A novel clinician interface to improve clinician access to up-to-date genetic results. J Am Med Inform Assoc (2013) 0.97

Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma. Cell Cycle (2012) 0.95

Germline mutation in the RAD51B gene confers predisposition to breast cancer. BMC Cancer (2013) 0.95

Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers. Carcinogenesis (2013) 0.95

Common breast cancer risk variants in the post-COGS era: a comprehensive review. Breast Cancer Res (2013) 0.94

Description of selected characteristics of familial glioma patients - results from the Gliogene Consortium. Eur J Cancer (2013) 0.94

Current strategies for the prevention of breast cancer. Breast Cancer (Dove Med Press) (2014) 0.93

PinX1: a sought-after major tumor suppressor at human chromosome 8p23. Oncotarget (2011) 0.92

Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial. Cancer Epidemiol Biomarkers Prev (2009) 0.92

Association of microRNA-499 rs3746444 polymorphism with cancer risk: evidence from 7188 cases and 8548 controls. PLoS One (2012) 0.89

DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas. Carcinogenesis (2011) 0.87

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. PLoS One (2013) 0.86

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence". Cancer Metastasis Rev (2013) 0.86

Enhancing radiotherapy through a greater understanding of homologous recombination. Semin Radiat Oncol (2010) 0.85

Cancer and longevity--is there a trade-off? A study of cooccurrence in Danish twin pairs born 1900-1918. J Gerontol A Biol Sci Med Sci (2012) 0.85

Proteomic approaches in biomarker discovery: new perspectives in cancer diagnostics. ScientificWorldJournal (2014) 0.85

Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent. BMC Med Genet (2013) 0.84

Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example. Sci Rep (2015) 0.84

Association between NFKB1 -94ins/del ATTG Promoter Polymorphism and Cancer Susceptibility: An Updated Meta-Analysis. Int J Genomics (2014) 0.83

Dysregulation of the homeobox transcription factor gene HOXB13: role in prostate cancer. Pharmgenomics Pers Med (2014) 0.83

SNP variants at the MAP3K1/SETD9 locus 5q11.2 associate with somatic PIK3CA variants in breast cancers. Eur J Hum Genet (2016) 0.82

Recent advances in understanding of interactions between genes and diet in the etiology of colorectal cancer. World J Gastrointest Oncol (2010) 0.82

Systematic evaluation of cancer risk associated with DNMT3B polymorphisms. J Cancer Res Clin Oncol (2014) 0.82

Chromosomal aberrations associated with clonal evolution and leukemic transformation in fanconi anemia: clinical and biological implications. Anemia (2012) 0.82

Utility of genome-wide association study findings: prostate cancer as a translational research paradigm. J Intern Med (2012) 0.81

Common low-penetrance risk variants associated with breast cancer in Polish women. BMC Cancer (2013) 0.81

Heterozygote FANCD2 mutations associated with childhood T Cell ALL and testicular seminoma. Fam Cancer (2012) 0.81

Colorectal Cancer Incidence Rates in the Louisiana Acadian Parishes Demonstrated to be Among the Highest in the United States. Clin Transl Gastroenterol (2014) 0.81

Consistency of BRCA1 and BRCA2 Variant Classifications Among Clinical Diagnostic Laboratories. JCO Precis Oncol (2017) 0.80

2011 Presidential Address: from classroom to courtroom to clinic-closing the gaps in human genetics education. Am J Hum Genet (2012) 0.80

HOXB13 and other high penetrant genes for prostate cancer. Asian J Androl (2016) 0.80

The emerging role of QSOX1 in cancer. Antioxid Redox Signal (2014) 0.79

NFKB1 -94insertion/deletion ATTG polymorphism and cancer risk: Evidence from 50 case-control studies. Oncotarget (2017) 0.79

Central nervous system abnormalities in Fanconi anaemia: patterns and frequency on magnetic resonance imaging. Br J Radiol (2015) 0.78

Management of the asymptomatic BRCA mutation carrier. Appl Clin Genet (2010) 0.78

Breast cancer in the young: role of the geneticist. J Thorac Dis (2013) 0.78

Statins and Breast Cancer: Future Directions in Chemoprevention. Curr Breast Cancer Rep (2013) 0.78

Association between mitogen-activated protein kinase kinase kinase 1 polymorphisms and breast cancer susceptibility: a meta-analysis of 20 case-control studies. PLoS One (2014) 0.77

Could triaging family history of cancer during palliative care enable earlier genetic counseling intervention? J Palliat Med (2013) 0.77

Genetic association between NFKB1 -94 ins/del ATTG Promoter Polymorphism and cancer risk: a meta-analysis of 42 case-control studies. Sci Rep (2016) 0.77

Prostate cancer: from the pathophysiologic implications of some genetic risk factors to translation in personalized cancer treatments. Cancer Gene Ther (2014) 0.77

Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer. J Pathol (2017) 0.77

Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy. Case Rep Oncol Med (2014) 0.76

Evaluation of functional genetic variants for breast cancer risk: results from the Shanghai breast cancer study. Am J Epidemiol (2011) 0.76

Cancer survivors: familial risk perception and management advice given to their relatives. Fam Cancer (2011) 0.76

ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry. PLoS One (2016) 0.76

Association between the COMT Val158Met polymorphism and risk of cancer: evidence from 99 case-control studies. Onco Targets Ther (2015) 0.75

Translating genetics beyond bench and bedside: A comparative perspective on health care infrastructures for 'familial' breast cancer. Appl Transl Genom (2016) 0.75

FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome. Int J Cancer (2016) 0.75

Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras. Oncotarget (2016) 0.75

Identification of genetic markers with synergistic survival effect in cancer. BMC Syst Biol (2013) 0.75

Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series. Gynecol Oncol Rep (2015) 0.75

Precision targeted therapy of ovarian cancer. J Control Release (2016) 0.75

Dysregulation of ubiquitin ligases in cancer. Drug Resist Updat (2015) 0.75

A model for patient-direct screening and referral for familial cancer risk. Fam Cancer (2016) 0.75

Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples. Oncotarget (2016) 0.75

The Angelina Jolie Effect in Jewish Law: Prophylactic Mastectomy and Oophorectomy in BRCA Carriers. Rambam Maimonides Med J (2015) 0.75

An updated meta-analysis of 37 case-control studies on the association between NFKB1 -94ins/del ATTG promoter polymorphism and cancer susceptibility. Oncotarget (2016) 0.75

Gynecologic care for breast cancer survivors: assisting in the transition to wellness. Am J Obstet Gynecol (2011) 0.75

DNA repair/replication transcripts are down regulated in patients with Fragile X Syndrome. BMC Res Notes (2013) 0.75

Exploring the Mechanisms of Gastrointestinal Cancer Development Using Deep Sequencing Analysis. Cancers (Basel) (2015) 0.75

Multiple malignancies in a single patient : a glimpse into 30 years of interdisciplinary oncology. Strahlenther Onkol (2012) 0.75

[Genes beyond BRCA1 and BRCA2 for hereditary breast cancer]. Wien Med Wochenschr (2010) 0.75

Current condition of genetic medicine for hereditary breast cancer. Mol Clin Oncol (2017) 0.75

Preoperative genetic testing impacts surgical decision making in BRCA mutation carriers with breast cancer: a retrospective cohort analysis. Hered Cancer Clin Pract (2017) 0.75

Other cancers in lung cancer families are overwhelmingly smoking-related cancers. ERJ Open Res (2017) 0.75

CASP8 -652 6N insertion/deletion polymorphism and overall cancer risk: evidence from 49 studies. Oncotarget (2017) 0.75