Published in J Neurochem on April 01, 1991
Active efflux across the blood-brain barrier: role of the solute carrier family. NeuroRx (2005) 1.11
The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication. Front Cell Neurosci (2014) 0.80
Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility. BMJ (2001) 2.74
Diet, antioxidant status, and smoking habits in French men. Am J Clin Nutr (1998) 2.41
A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res (1999) 2.13
Segregation analysis and variance components analysis of bone mineral density in healthy families. J Bone Miner Res (1995) 1.55
Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight. Ann Hum Genet (2000) 1.53
Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J (2005) 1.53
Choroid plexus in the central nervous system: biology and physiopathology. J Neuropathol Exp Neurol (2000) 1.48
Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood. Clin Chem (1991) 1.42
Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics. J Neurosci (1999) 1.40
Aspartate aminotransferase and alanine aminotransferase activities in plasma: statistical distributions, individual variations, and reference values. Clin Chem (1975) 1.39
An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene. Hum Genet (1990) 1.36
The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence. DNA Cell Biol (1991) 1.35
Intima-media thickness and diameter of carotid and femoral arteries in children, adolescents and adults from the Stanislas cohort: effect of age, sex, anthropometry and blood pressure. J Hypertens (1998) 1.29
Determination of serum cystatin C: biological variation and reference values. Clin Chem Lab Med (2001) 1.26
gamma-Glutamyltransferase dependent generation of reactive oxygen species from a glutathione/transferrin system. Free Radic Biol Med (1998) 1.26
Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease. Neurobiol Aging (2000) 1.24
Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits. Clin Chem (1995) 1.24
Allele frequency distribution of the (TG)n(AG)m microsatellite in the apolipoprotein C-II gene. Genomics (1992) 1.20
Cloning of the cDNA encoding human brain trypsinogen and characterization of its product. Gene (1993) 1.18
Total bone and liver alkaline phosphatases in plasma: biological variations and reference limits. Clin Chem (1983) 1.16
Physiology of blood-brain interfaces in relation to brain disposition of small compounds and macromolecules. Mol Pharm (2013) 1.15
UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. Biochem Pharmacol (1983) 1.14
Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients. J Neurochem (1998) 1.11
Evidence for neurogenic transmission inducing degenerative cartilage damage distant from local inflammation. Arthritis Rheum (1999) 1.07
Apolipoprotein E serum concentration and polymorphism in six European countries: the ApoEurope Project. Atherosclerosis (2000) 1.06
Need for revisiting the concept of reference values. Clin Chem Lab Med (2000) 1.04
Subcellular distribution of cytochrome P-450 in the brain. Brain Res (1986) 1.04
Dietary intakes, eating style and overweight in the Stanislas Family Study. Int J Obes Relat Metab Disord (2000) 1.03
Pefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen. Antimicrob Agents Chemother (2000) 1.03
Human aminopeptidases: a review of the literature. J Clin Chem Clin Biochem (1988) 1.03
Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4. J Biol Chem (1993) 1.03
Wine, beer, and mortality in middle-aged men from eastern France. Arch Intern Med (1999) 1.03
A multilocus genotyping assay for cardiovascular disease. Clin Chem Lab Med (1998) 1.01
Drug metabolizing enzymes in the brain and cerebral microvessels. Brain Res Brain Res Rev (1991) 1.01
Transendothelial permeability changes induced by free radicals in an in vitro model of the blood-brain barrier. Free Radic Biol Med (1999) 1.00
Multivariate genetic analysis of high density lipoprotein particles. Atherosclerosis (1992) 1.00
Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain. Biochem Pharmacol (1993) 0.98
High sensitivity C-reactive protein: biological variations and reference limits. Clin Chem Lab Med (2000) 0.98
Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J Neurochem (1994) 0.98
Genetics strongly determines the wall thickness of the left and right carotid arteries. Hum Genet (1998) 0.98
Serum myeloperoxidase concentration in a healthy population: biological variations, familial resemblance and new genetic polymorphisms. Eur J Hum Genet (2001) 0.97
Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Neurobiol Aging (2001) 0.97
Effect of alcohol consumption on blood antioxidant nutrients and oxidative stress indicators. Am J Clin Nutr (1994) 0.97
Expression of multiple gamma-glutamyltransferase genes in man. Biochem J (1994) 0.96
In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability. J Neuropathol Exp Neurol (2000) 0.96
An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data. Am J Hum Genet (1989) 0.95
Blood activity of Cu/Zn superoxide dismutase, glutathione peroxidase and catalase in Alzheimer's disease: a case-control study. Gerontology (1990) 0.95
Metabolic determinants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations: a family study with part of the Stanislas Cohort. Arterioscler Thromb Vasc Biol (1998) 0.94
Five-year alterations in BMI are associated with clustering of changes in cardiovascular risk factors in a gender-dependant way: the Stanislas study. Int J Obes (Lond) (2008) 0.94
Biological variations and genetic reference values for apolipoprotein E serum concentrations: results from the STANISLAS cohort study. Clin Chem (1998) 0.93
In vitro N-glucuronidation of a novel antiepileptic drug, lamotrigine, by human liver microsomes. J Pharmacol Exp Ther (1992) 0.92
Association of a functional 5-HT transporter gene polymorphism with anorexia nervosa and food intake. Mol Psychiatry (2001) 0.92
Relations between reported alcohol consumption and certain biological variables in an "unselected" population. Clin Chem (1979) 0.92
Conformation of apolipoprotein E both in free and in lipid-bound form may determine the avidity of triglyceride-rich lipoproteins to the LDL receptor: structural and kinetic study. Biochim Biophys Acta (2000) 0.91
Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain. Cell Mol Biol (Noisy-le-grand) (1999) 0.91
Family study of lipoprotein lipase gene polymorphisms and plasma triglyceride levels. Genet Epidemiol (1996) 0.91
ELISA of 6-beta-hydroxycortisol in human urine: diurnal variations and effects of antiepileptic therapy. Clin Chim Acta (1986) 0.90
Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry. FEBS Lett (1998) 0.90
The chemical modification of human liver UDP-glucuronosyltransferase UGT1*6 reveals the involvement of a carboxyl group in catalysis. FEBS Lett (1994) 0.89
Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including man. Xenobiotica (1986) 0.89
An improved method for phenotyping individuals for the human serum paraoxonase arylesterase polymorphism. Ann Biol Clin (Paris) (1986) 0.89
Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues. Biochem Pharmacol (1992) 0.89
Electrophoretic mobility, rosette formation and surface immunoglobulins of gradient fractionated human blood lymphocytes. Biomedicine (1974) 0.88
5-HT2A receptor gene polymorphism is associated with food and alcohol intake in obese people. Int J Obes Relat Metab Disord (2000) 0.88
Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. J Lipid Res (1996) 0.88
Genetic Polymorphism of CYP2C19 gene in the Stanislas cohort. A link with inflammation. Ann Hum Genet (2008) 0.88
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. Biochem J (1999) 0.88
Glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes: enzyme inhibition by drugs and steroid hormones. Biochim Biophys Acta (1992) 0.88
Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis. Brain Res Mol Brain Res (2001) 0.87
Stable expression of two human UDP-glucuronosyltransferase cDNAs in V79 cell cultures. Mol Pharmacol (1991) 0.87
Soluble transferrin receptor (sTfR): biological variations and reference limits. Clin Chem Lab Med (2001) 0.87
Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. J Lipid Res (2001) 0.87
Proteoglycan and collagen biochemical variations during fluoroquinolone-induced chondrotoxicity in mice. Antimicrob Agents Chemother (1999) 0.87
LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women. Eur J Clin Invest (2001) 0.86
Frequencies of five genetic polymorphisms in coronarographed patients and effects on lipid levels in a supposedly healthy population. Clin Genet (1996) 0.86
Total cholinesterase in plasma: biological variations and reference limits. Clin Chem (1985) 0.86
Biological variations in hyperlipidemic children and adolescents treated with fenofibrate. Clin Chim Acta (1981) 0.86
Weights at birth and in early infancy, systolic pressure, and left ventricular structure in subjects aged 8 to 24 years. Hypertension (1996) 0.86
Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease. J Neurol Sci (1997) 0.85
Differential oxidation of apolipoprotein E isoforms and interaction with phospholipids. Free Radic Biol Med (2000) 0.85
Kinetic study of glutamate transport in rat brain mitochondria. J Neurochem (1977) 0.85
Albendazole sulfonation by rat liver cytochrome P-450c. J Pharmacol Exp Ther (1988) 0.85
A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-O-glucosides of bile acids in human liver microsomes. J Biol Chem (1993) 0.85
Evidence for the pro-oxidant effect of gamma-glutamyltranspeptidase-related enzyme. Free Radic Biol Med (2000) 0.85
The glucuronosyltransferases: what progress can pharmacologists expect from molecular biology and cellular enzymology? Biochem Pharmacol (1987) 0.85
A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. Mol Pharmacol (1994) 0.85
Association of CYP2A6*1B genetic variant with the amount of smoking in French adults from the Stanislas cohort. Pharmacogenomics J (2005) 0.84
Changes in serum apolipoprotein and lipoprotein profile induced by chronic alcohol consumption and withdrawal: determinant effect on heart disease? Clin Chem (1996) 0.84
Phenobarbital inducible UDP-glucuronosyltransferase is responsible for glucuronidation of 3'-azido-3'-deoxythymidine: characterization of the enzyme in human and rat liver microsomes. Arch Biochem Biophys (1990) 0.84
Heritability of serum hs-CRP concentration and 5-year changes in the Stanislas family study: association with apolipoprotein E alleles. Genes Immun (2007) 0.84
Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. Biochem Biophys Res Commun (1993) 0.84
Stereoselective esterase activity of human serum albumin toward ketoprofen glucuronide. Mol Pharmacol (1995) 0.83
Glucuronidation of apomorphine. Life Sci (2000) 0.83
Inducibility of rat brain drug-metabolizing enzymes. Eur J Drug Metab Pharmacokinet (1988) 0.83