Published in Histochem Cell Biol on November 13, 2008
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Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis. Am J Pathol (2010) 1.68
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Chick chorioallantoic membrane (CAM) assay as an in vivo model to study the effect of newly identified molecules on ovarian cancer invasion and metastasis. Int J Mol Sci (2012) 1.29
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Morphologic characterization of osteosarcoma growth on the chick chorioallantoic membrane. BMC Res Notes (2010) 1.03
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A rapid in vivo assay system for analyzing the organogenetic capacity of human kidney cells. Organogenesis (2011) 0.87
IRX1 influences peritoneal spreading and metastasis via inhibiting BDKRB2-dependent neovascularization on gastric cancer. Oncogene (2011) 0.85
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The in ovo CAM-assay as a xenograft model for sarcoma. J Vis Exp (2013) 0.83
MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma. Oncotarget (2016) 0.82
Chicken chorioallantoic membrane as a reliable model to evaluate osteosarcoma-an experimental approach using SaOS2 cell line. Biol Proced Online (2015) 0.82
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Re-characterization of established human retinoblastoma cell lines. Histochem Cell Biol (2014) 0.82
Dynamic interactions between cancer cells and the embryonic microenvironment regulate cell invasion and reveal EphB6 as a metastasis suppressor. Mol Cancer Res (2014) 0.82
Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth. J Exp Clin Cancer Res (2016) 0.82
Repurposing the antipsychotic trifluoperazine as an antimetastasis agent. Mol Pharmacol (2014) 0.81
Invadosomes in their natural habitat. Eur J Cell Biol (2014) 0.81
INPP4B suppresses prostate cancer cell invasion. Cell Commun Signal (2014) 0.79
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Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells. Oncotarget (2016) 0.79
SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases. Mol Biol Cell (2016) 0.79
The chick chorioallantoic membrane: a model of molecular, structural, and functional adaptation to transepithelial ion transport and barrier function during embryonic development. J Biomed Biotechnol (2010) 0.79
IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells. BMC Cancer (2015) 0.79
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The chick chorioallantoic membrane as an in vivo xenograft model for Burkitt lymphoma. BMC Cancer (2014) 0.77
Marine compounds inhibit growth of multiple myeloma in vitro and in vivo. Oncotarget (2015) 0.77
Application of the chick embryo chorioallantoic membrane in neurosurgery disease. Int J Med Sci (2014) 0.77
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miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. Sci Rep (2016) 0.76
Long noncoding RNA OR3A4 promotes metastasis and tumorigenicity in gastric cancer. Oncotarget (2016) 0.76
Establishment of a human multiple myeloma xenograft model in the chicken to study tumor growth, invasion and angiogenesis. J Vis Exp (2015) 0.76
Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing. Sci Rep (2017) 0.75
Feasibility Study of Ex Ovo Chick Chorioallantoic Artery Model for Investigating Pulsatile Variation of Arterial Geometry. PLoS One (2015) 0.75
Effect of Laryngeal Squamous Cell Carcinoma Tissue Implantation on the Chick Embryo Chorioallantoic Membrane: Morphometric Measurements and Vascularity. Biomed Res Int (2015) 0.75
Fluorescence characteristics of human Barrett tissue specimens grafted on chick chorioallantoic membrane. Lasers Med Sci (2015) 0.75
The CAM cancer xenograft as a model for initial evaluation of MR labelled compounds. Sci Rep (2017) 0.75
The Effect of Sodium Valproate on the Glioblastoma U87 Cell Line Tumor Development on the Chicken Embryo Chorioallantoic Membrane and on EZH2 and p53 Expression. Biomed Res Int (2017) 0.75
Monitoring brain development of chick embryos in vivo using 3.0 T MRI: subdivision volume change and preliminary structural quantification using DTI. BMC Dev Biol (2015) 0.75
Use of the Chick Embryo Model in Uveal Melanoma. Ocul Oncol Pathol (2015) 0.75
The chick eye in vision research: An excellent model for the study of ocular disease. Prog Retin Eye Res (2017) 0.75
Extending the knowledge in histochemistry and cell biology. Histochem Cell Biol (2009) 0.75
Live-cell confocal microscopy and quantitative 4D image analysis of anchor-cell invasion through the basement membrane in Caenorhabditis elegans. Nat Protoc (2017) 0.75
Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays. Int J Oncol (2017) 0.75
Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell (2006) 13.79
Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med (2008) 13.54
Paradoxical roles of the immune system during cancer development. Nat Rev Cancer (2006) 10.57
Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell (2005) 9.06
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Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene (2003) 1.59
Inflammation, proteases and cancer. Eur J Cancer (2006) 1.52
CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am J Pathol (2008) 1.52
Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene (2001) 1.51
Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination. Cancer Res (2005) 1.47
Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). J Biol Chem (2004) 1.41
Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol (2008) 1.38
Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor-specific fluorescent ligands. Int J Cancer (2008) 1.34
Experimental model for quantitative study of metastasis. Cancer Res (1980) 1.32
Transepithelial invasion and intramesenchymal infiltration of the chick embryo chorioallantois by tumor cell lines. Cancer Res (1982) 1.22
Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood (2005) 1.17
Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells. FEBS Lett (2007) 1.16
Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry. Cytometry A (2005) 1.16
Detection of circulating tumor cells in patients with urothelial cancer. Ann Oncol (2008) 1.08
Avian heterophils in inflammation and disease resistance. Poult Sci (1998) 1.03
Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor. J Biol Chem (2008) 0.95
Targeting the proteome/epitome, implementation of subtractive immunization. Biochem Biophys Res Commun (2003) 0.89
Capillary plexus development in the day five to day six chick chorioallantoic membrane is inhibited by cytochalasin D and suramin. J Exp Zool (2002) 0.88
Detection of tumor-associated circulating mRNA in serum, plasma and blood cells from patients with disseminated malignant melanoma. Oncol Rep (2001) 0.86
IFN-gamma priming of chicken heterophils upregulates the expression of proinflammatory and Th1 cytokine mRNA following receptor-mediated phagocytosis of Salmonella enterica serovar enteritidis. J Interferon Cytokine Res (2005) 0.85
Fate and characterization of circulating tumor cells in a NOD/SCID mouse model of human hepatocellular carcinoma. Oncogene (2006) 0.82
Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev (2006) 7.92
Viral nanoparticles as tools for intravital vascular imaging. Nat Med (2006) 2.46
Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Rev (2003) 2.39
The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell (2008) 2.27
Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis. Proc Natl Acad Sci U S A (2007) 2.27
A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction. Cancer Res (2002) 1.97
Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene (2003) 1.59
Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination. Cancer Res (2005) 1.47
Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions. Biochim Biophys Acta (2009) 1.46
Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). J Biol Chem (2004) 1.41
Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol (2008) 1.38
Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation. Am J Pathol (2011) 1.37
Twist1 induces CCL2 and recruits macrophages to promote angiogenesis. Cancer Res (2013) 1.24
Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Mol Cancer Res (2009) 1.18
Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. Biochem J (2003) 1.18
Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood (2005) 1.17
Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion. Am J Pathol (2009) 1.15
Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. J Biol Chem (2009) 1.14
Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. J Biol Chem (2006) 1.12
The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges. IUBMB Life (2009) 1.11
The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles. Front Biosci (2008) 1.11
Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem (2008) 1.09
Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis. Thromb Haemost (2003) 1.08
Genetic reprogramming of tumor cells by zinc finger transcription factors. Proc Natl Acad Sci U S A (2005) 1.07
Cell surface remodeling by plasmin: a new function for an old enzyme. J Biomed Biotechnol (2012) 1.04
Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9. Blood (2013) 1.03
The primacy of β1 integrin activation in the metastatic cascade. PLoS One (2012) 1.03
Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination. Cancer Res (2013) 0.96
Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesity. Arterioscler Thromb Vasc Biol (2009) 0.94
Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells. Neoplasia (2011) 0.93
Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems. Clin Exp Metastasis (2009) 0.92
A novel mode of intervention with serine protease activity: targeting zymogen activation. J Biol Chem (2008) 0.91
Targeting the proteome/epitome, implementation of subtractive immunization. Biochem Biophys Res Commun (2003) 0.89
The DARC side of metastasis: shining a light on KAI1-mediated metastasis suppression in the vascular tunnel. Cancer Cell (2006) 0.86
Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol Pharm (2010) 0.86
Contribution of leptin receptor N-linked glycans to leptin binding. Biochem J (2008) 0.86
Combating angiogenesis early: potential of targeting tumor-recruited neutrophils in cancer therapy. Future Oncol (2012) 0.80
Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism. Mol Cancer Res (2012) 0.79
Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha 2-macroglobulin. Evidence for two forms differing primarily in their bait region sequences. J Biol Chem (2002) 0.79
Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies. Biochem J (2011) 0.79
Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors. Biol Chem (2003) 0.75
Human/chicken urokinase chimeras demonstrate sequences outside the serine protease domain that dictate autoactivation. Thromb Haemost (2003) 0.75