PubRank

James P Quigley

Author PubWeight™ 58.62‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 2006 7.92
2 Viral nanoparticles as tools for intravital vascular imaging. Nat Med 2006 2.46
3 Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Rev 2003 2.39
4 The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell 2008 2.27
5 Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis. Proc Natl Acad Sci U S A 2007 2.27
6 A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction. Cancer Res 2002 1.97
7 Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochem Cell Biol 2008 1.59
8 Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 2003 1.59
9 Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination. Cancer Res 2005 1.47
10 Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions. Biochim Biophys Acta 2009 1.46
11 Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). J Biol Chem 2004 1.41
12 Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol 2008 1.38
13 Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation. Am J Pathol 2011 1.37
14 Twist1 induces CCL2 and recruits macrophages to promote angiogenesis. Cancer Res 2013 1.24
15 Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta. J Biol Chem 2010 1.19
16 Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Mol Cancer Res 2009 1.18
17 Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. Biochem J 2003 1.18
18 Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood 2005 1.17
19 Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion. Am J Pathol 2009 1.15
20 Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. J Biol Chem 2009 1.14
21 Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. J Biol Chem 2006 1.12
22 The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges. IUBMB Life 2009 1.11
23 The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles. Front Biosci 2008 1.11
24 Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem 2008 1.09
25 Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis. Thromb Haemost 2003 1.08
26 Genetic reprogramming of tumor cells by zinc finger transcription factors. Proc Natl Acad Sci U S A 2005 1.07
27 Cell surface remodeling by plasmin: a new function for an old enzyme. J Biomed Biotechnol 2012 1.04
28 Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9. Blood 2013 1.03
29 The primacy of β1 integrin activation in the metastatic cascade. PLoS One 2012 1.03
30 Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination. Cancer Res 2013 0.96
31 Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis. J Biol Chem 2007 0.95
32 Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesity. Arterioscler Thromb Vasc Biol 2009 0.94
33 Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells. Neoplasia 2011 0.93
34 Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems. Clin Exp Metastasis 2009 0.92
35 A novel mode of intervention with serine protease activity: targeting zymogen activation. J Biol Chem 2008 0.91
36 Targeting the proteome/epitome, implementation of subtractive immunization. Biochem Biophys Res Commun 2003 0.89
37 The DARC side of metastasis: shining a light on KAI1-mediated metastasis suppression in the vascular tunnel. Cancer Cell 2006 0.86
38 Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol Pharm 2010 0.86
39 Contribution of leptin receptor N-linked glycans to leptin binding. Biochem J 2008 0.86
40 Combating angiogenesis early: potential of targeting tumor-recruited neutrophils in cancer therapy. Future Oncol 2012 0.80
41 Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies. Biochem J 2011 0.79
42 Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha 2-macroglobulin. Evidence for two forms differing primarily in their bait region sequences. J Biol Chem 2002 0.79
43 Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism. Mol Cancer Res 2012 0.79
44 Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors. Biol Chem 2003 0.75
45 Human/chicken urokinase chimeras demonstrate sequences outside the serine protease domain that dictate autoactivation. Thromb Haemost 2003 0.75