Published in Genes Chromosomes Cancer on February 01, 2009
PTTG1 overexpression in adrenocortical cancer is associated with poor survival and represents a potential therapeutic target. Surgery (2013) 0.95
Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+ depletion in fermenting yeast. J Biol Chem (2013) 0.87
Inhibitory effects of a selective Jak2 inhibitor on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT20 cells. Onco Targets Ther (2017) 0.75
Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis. Nat Genet (2002) 2.32
Supercomplex assembly determines electron flux in the mitochondrial electron transport chain. Science (2013) 2.24
Cerebellar ataxia with coenzyme Q10 deficiency: diagnosis and follow-up after coenzyme Q10 supplementation. J Neurol Sci (2006) 1.95
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis. Hum Mol Genet (2007) 1.67
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy. Autophagy (2009) 1.65
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J (2008) 1.41
Caloric restriction increases learning consolidation and facilitates synaptic plasticity through mechanisms dependent on NR2B subunits of the NMDA receptor. J Neurosci (2007) 1.33
Transgenic tobacco plants overexpressing chitinases of fungal origin show enhanced resistance to biotic and abiotic stress agents. Plant Physiol (2006) 1.18
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease. Arthritis Res Ther (2010) 1.18
Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency. J Med Genet (2012) 1.16
Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts. FASEB J (2011) 1.16
Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons. FEBS Lett (2005) 1.11
Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J Biol Chem (2004) 1.09
Analysis of coenzyme Q10 in muscle and fibroblasts for the diagnosis of CoQ10 deficiency syndromes. Clin Biochem (2008) 1.07
The way to determine coenzyme Q. J Am Coll Cardiol (2013) 1.07
Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines. Free Radic Biol Med (2005) 1.04
Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation. Mol Biol Cell (2009) 0.98
N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes. Chem Biol Interact (2009) 0.96
Molecular bases of caloric restriction regulation of neuronal synaptic plasticity. Mol Neurobiol (2008) 0.96
The role of ubiquinone in Caenorhabditis elegans longevity. Ageing Res Rev (2004) 0.96
Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice. PLoS One (2010) 0.96
Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma. PLoS One (2011) 0.95
Specificity of coenzyme Q10 for a balanced function of respiratory chain and endogenous ubiquinone biosynthesis in human cells. Biochim Biophys Acta (2005) 0.92
The apoptotic microtubule network preserves plasma membrane integrity during the execution phase of apoptosis. Apoptosis (2007) 0.92
Coenzyme Q distribution in HL-60 human cells depends on the endomembrane system. Biochim Biophys Acta (2005) 0.91
Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis elegans. FASEB J (2003) 0.91
Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet. Exp Gerontol (2005) 0.90
Expression of hpttg proto-oncogene in lymphoid neoplasias. Oncogene (2002) 0.90
NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast. Aging Cell (2009) 0.90
Securin is a target of the UV response pathway in mammalian cells. Mol Cell Biol (2004) 0.89
Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis. PLoS One (2009) 0.89
Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans. Mech Ageing Dev (2008) 0.89
Prognostic significance of human pituitary tumor-transforming gene immunohistochemical expression in differentiated thyroid cancer. J Clin Endocrinol Metab (2006) 0.89
Is coenzyme Q a key factor in aging? Mech Ageing Dev (2010) 0.88
PTTG1/securin modulates microtubule nucleation and cell migration. Mol Biol Cell (2011) 0.88
The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction. Biosci Rep (2012) 0.88
UV-induced degradation of securin is mediated by SKP1-CUL1-beta TrCP E3 ubiquitin ligase. J Cell Sci (2008) 0.88
Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet. Exp Gerontol (2007) 0.88
Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J (2011) 0.88
Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells. Biochem J (2003) 0.88
The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction. J Gerontol A Biol Sci Med Sci (2012) 0.87
Clinical, biochemical and molecular aspects of cerebellar ataxia and Coenzyme Q10 deficiency. Cerebellum (2007) 0.87
Hydrogen peroxide- and cell-density-regulated expression of NADH-cytochrome b5 reductase in HeLa cells. J Bioenerg Biomembr (2003) 0.87
Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+ depletion in fermenting yeast. J Biol Chem (2013) 0.87
Coenzyme Q and the regulation of intracellular steady-state levels of superoxide in HL-60 cells. Biofactors (2005) 0.86
Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease. Br J Pharmacol (2012) 0.85
Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria. Apoptosis (2011) 0.85
Coenzyme Q10 deficiencies in neuromuscular diseases. Adv Exp Med Biol (2009) 0.84
Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats. J Gerontol A Biol Sci Med Sci (2013) 0.84
The characterization of the Caenorhabditis elegans mitochondrial thioredoxin system uncovers an unexpected protective role of thioredoxin reductase 2 in β-amyloid peptide toxicity. Antioxid Redox Signal (2012) 0.83
Mitochondrial responsibility in ageing process: innocent, suspect or guilty. Biogerontology (2015) 0.83
Coenzyme Q10 deficiency associated with a mitochondrial DNA depletion syndrome: a case report. Clin Biochem (2008) 0.83
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs. Anticancer Drugs (2010) 0.83
CYB5R3: a key player in aerobic metabolism and aging? Aging (Albany NY) (2009) 0.82
Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90. Mol Cancer Ther (2008) 0.82
C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development. Biofactors (2005) 0.82
Genetic evidence for the requirement of the endocytic pathway in the uptake of coenzyme Q6 in Saccharomyces cerevisiae. Biochim Biophys Acta (2009) 0.82
NAD(P)H:quinone oxidoreductase 1 expression, hydrogen peroxide levels, and growth phase in HeLa cells. Methods Enzymol (2004) 0.82
A novel plasma membrane quinone reductase and NAD(P)H:quinone oxidoreductase 1 are upregulated by serum withdrawal in human promyelocytic HL-60 cells. J Bioenerg Biomembr (2002) 0.81
Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice. Age (Dordr) (2012) 0.81
Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane of Caenorhabditis elegans. FEBS Lett (2006) 0.81
Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues. Free Radic Biol Med (2011) 0.81
Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver. Toxicol Lett (2011) 0.81
Characterization of CoQ₁₀ biosynthesis in fibroblasts of patients with primary and secondary CoQ₁₀ deficiency. J Inherit Metab Dis (2013) 0.80
Dietary oil modifies the plasma proteome during aging in the rat. Age (Dordr) (2011) 0.80
Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2. Antioxid Redox Signal (2014) 0.80
Differential regulation of hepatic apoptotic pathways by dietary olive and sunflower oils in the aging rat. Exp Gerontol (2006) 0.80
Coenzyme Q10 and alpha-tocopherol protect against amitriptyline toxicity. Toxicol Appl Pharmacol (2009) 0.80
Novel small RNA expression libraries uncover hsa-miR-30b and hsa-miR-30c as important factors in anoikis resistance. RNA (2013) 0.79
Ubiquinol inhibition of neutral sphingomyelinase in liver plasma membrane: specific inhibition of the Mg(2+)-dependent enzyme and role of isoprenoid chain. Biochem Biophys Res Commun (2002) 0.78
Caenorhabditis elegans ubiquinone biosynthesis genes. Biofactors (2003) 0.78
Modulation of endogenous antioxidant activity by resveratrol and exercise in mouse liver is age dependent. J Gerontol A Biol Sci Med Sci (2013) 0.78
Physical activity affects plasma coenzyme Q10 levels differently in young and old humans. Biogerontology (2014) 0.78
Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients. Clin Biochem (2010) 0.78
Muscle physiology changes induced by every other day feeding and endurance exercise in mice: effects on physical performance. PLoS One (2010) 0.77
Stabilization of extracellular ascorbate mediated by coenzyme Q transmembrane electron transport. Methods Enzymol (2004) 0.77
Survival transcriptome in the coenzyme Q10 deficiency syndrome is acquired by epigenetic modifications: a modelling study for human coenzyme Q10 deficiencies. BMJ Open (2013) 0.77
"AcCoA"lade for energy and life span. Cell Metab (2009) 0.77
Protein kinase C as an effector of lipid-derived second messengers. Methods Mol Biol (2009) 0.77
Post-transcriptional control of a glucoamylase gene from Trichoderma harzianum under stress conditions. Mol Microbiol (2005) 0.76