Published in J Chromatogr B Analyt Technol Biomed Life Sci on November 06, 2008
High-sensitivity analytical approaches for the structural characterization of glycoproteins. Chem Rev (2013) 1.23
Addressing the challenge of defining valid proteomic biomarkers and classifiers. BMC Bioinformatics (2010) 1.16
Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease. PLoS One (2014) 0.95
Urinary proteomics as a novel tool for biomarker discovery in kidney diseases. J Zhejiang Univ Sci B (2010) 0.93
Analytical glycobiology at high sensitivity: current approaches and directions. Glycoconj J (2012) 0.90
Advances in urinary proteome analysis and biomarker discovery in pediatric renal disease. Pediatr Nephrol (2009) 0.87
Seminal plasma as a source of prostate cancer peptide biomarker candidates for detection of indolent and advanced disease. PLoS One (2013) 0.82
Protein interactome of muscle invasive bladder cancer. PLoS One (2015) 0.82
Mass spectrometry-based proteomics for pre-eclampsia and preterm birth. Int J Mol Sci (2015) 0.81
Urinary Proteomics Pilot Study for Biomarker Discovery and Diagnosis in Heart Failure with Reduced Ejection Fraction. PLoS One (2016) 0.80
Proteomics, lipidomics, metabolomics: a mass spectrometry tutorial from a computer scientist's point of view. BMC Bioinformatics (2014) 0.80
Novel Urinary Peptidomic Classifier Predicts Incident Heart Failure. J Am Heart Assoc (2017) 0.76
iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination. PLoS One (2016) 0.75
Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study. Crit Care (2016) 0.75
Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency? Int J Chron Obstruct Pulmon Dis (2017) 0.75
Prediction of acute coronary syndromes by urinary proteome analysis. PLoS One (2017) 0.75
Comparison of different statistical approaches for urinary peptide biomarker detection in the context of coronary artery disease. BMC Bioinformatics (2016) 0.75
Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis. Int J Mol Sci (2016) 0.75
Regulation and role of Raf-1/B-Raf heterodimerization. Mol Cell Biol (2006) 4.84
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity. Hum Mol Genet (2005) 3.49
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol Cell (2007) 3.47
Signalling ballet in space and time. Nat Rev Mol Cell Biol (2010) 3.32
Clinical proteomics: A need to define the field and to begin to set adequate standards. Proteomics Clin Appl (2007) 2.84
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. Science (2004) 2.66
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier. Sci Signal (2010) 2.40
Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis. Lancet Oncol (2006) 2.29
Urinary proteomics in diabetes and CKD. J Am Soc Nephrol (2008) 2.12
Urine in clinical proteomics. Mol Cell Proteomics (2008) 2.05
Regulation of Raf-1 activation and signalling by dephosphorylation. EMBO J (2002) 1.99
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease. Mol Cell Proteomics (2010) 1.90
SNPHarvester: a filtering-based approach for detecting epistatic interactions in genome-wide association studies. Bioinformatics (2008) 1.85
Comparison of public peak detection algorithms for MALDI mass spectrometry data analysis. BMC Bioinformatics (2009) 1.84
Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell (2004) 1.79
Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis. Clin Cancer Res (2005) 1.78
Advances in urinary proteome analysis and biomarker discovery. J Am Soc Nephrol (2007) 1.77
Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition. Cancer Res (2010) 1.74
Raf family kinases: old dogs have learned new tricks. Genes Cancer (2011) 1.72
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway. Biochem J (2005) 1.70
Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. J Clin Oncol (2006) 1.67
Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proc Natl Acad Sci U S A (2008) 1.65
Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Mol Cell Biol (2002) 1.63
Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int (2005) 1.63
Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res (2004) 1.61
Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells. Lab Chip (2009) 1.61
Recommendations for biomarker identification and qualification in clinical proteomics. Sci Transl Med (2010) 1.59
Mass spectrometry for the detection of differentially expressed proteins: a comparison of surface-enhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry. Rapid Commun Mass Spectrom (2004) 1.57
CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics. Proteomics Clin Appl (2008) 1.57
Untying the regulation of the Raf-1 kinase. Arch Biochem Biophys (2002) 1.57
Quantitative urinary proteome analysis for biomarker evaluation in chronic kidney disease. J Proteome Res (2009) 1.56
Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species. Sci Signal (2010) 1.54
Extracellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK)-independent functions of Raf kinases. J Cell Sci (2002) 1.53
Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future. J Proteome Res (2007) 1.52
Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Nat Med (2006) 1.52
Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models. Bioinformatics (2008) 1.51
Computational approaches for analyzing information flow in biological networks. Sci Signal (2012) 1.49
Urinary proteome analysis identifies infants but not older children requiring pyeloplasty. Pediatr Nephrol (2010) 1.48
Urinary proteomic biomarkers in coronary artery disease. Mol Cell Proteomics (2007) 1.47
Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. Mol Cell (2011) 1.44
Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease. Circ Cardiovasc Genet (2014) 1.44
Urinary proteome analysis to exclude severe vesicoureteral reflux. Pediatrics (2012) 1.42
Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells. Cancer Res (2005) 1.41
Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway. J Cell Sci (2009) 1.41
Identification and validation of urinary biomarkers for differential diagnosis and evaluation of therapeutic intervention in anti-neutrophil cytoplasmic antibody-associated vasculitis. Mol Cell Proteomics (2009) 1.41
Systems biology-embedded target validation: improving efficacy in drug discovery. Wiley Interdiscip Rev Syst Biol Med (2013) 1.41
Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system. Cytokine Growth Factor Rev (2004) 1.39
Improved and Promising Identification of Human MicroRNAs by Incorporating a High-Quality Negative Set. IEEE/ACM Trans Comput Biol Bioinform (2015) 1.39
Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells. Diabetes (2003) 1.39
Urinary proteomics for early diagnosis in diabetic nephropathy. Diabetes (2012) 1.38
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5. Nat Cell Biol (2006) 1.36
When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling. Cell Commun Signal (2013) 1.36
Biomarker discovery by CE-MS enables sequence analysis via MS/MS with platform-independent separation. Electrophoresis (2006) 1.33
Proteomics applied to the clinical follow-up of patients after allogeneic hematopoietic stem cell transplantation. Blood (2004) 1.33
Inferring microRNA-disease associations by random walk on a heterogeneous network with multiple data sources. IEEE/ACM Trans Comput Biol Bioinform (2016) 1.33
The role of MAPK pathways in the action of chemotherapeutic drugs. Carcinogenesis (2002) 1.32
Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions. Mol Syst Biol (2009) 1.31
Proteomic patterns established with capillary electrophoresis and mass spectrometry for diagnostic purposes. Kidney Int (2004) 1.29
Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis. Hepatology (2011) 1.28
Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases. Electrophoresis (2007) 1.26
Capillary electrophoresis-mass spectrometry as a powerful tool in clinical diagnosis and biomarker discovery. Mass Spectrom Rev (2005) 1.26
Modeling and simulation of intracellular dynamics: choosing an appropriate framework. IEEE Trans Nanobioscience (2004) 1.25
Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise. BMC Syst Biol (2012) 1.25
Detection of acute tubulointerstitial rejection by proteomic analysis of urinary samples in renal transplant recipients. Am J Transplant (2005) 1.24
Pilot study of capillary electrophoresis coupled to mass spectrometry as a tool to define potential prostate cancer biomarkers in urine. Electrophoresis (2005) 1.24
Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells. Cell Signal (2011) 1.21
Urinary proteomics for prediction of preeclampsia. Hypertension (2011) 1.20
MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability. Mol Cell Biol (2009) 1.20
Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells. Anal Chem (2009) 1.20
PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells. Cell Signal (2010) 1.18
Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and Akt. Cancer Res (2010) 1.17
Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β. Cancer Res (2011) 1.17
Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway. J Biol Chem (2002) 1.17
Addressing the challenge of defining valid proteomic biomarkers and classifiers. BMC Bioinformatics (2010) 1.16
Crosstalk and signaling switches in mitogen-activated protein kinase cascades. Front Physiol (2012) 1.16
Determination of peptides and proteins in human urine with capillary electrophoresis-mass spectrometry, a suitable tool for the establishment of new diagnostic markers. J Chromatogr A (2003) 1.16
Phosphatase and feedback regulation of Raf-1 signaling. Cell Cycle (2007) 1.15
Impact of diabetic nephropathy and angiotensin II receptor blockade on urinary polypeptide patterns. Kidney Int (2005) 1.13
The secret life of kinases: functions beyond catalysis. Cell Commun Signal (2011) 1.13
Urinary proteomic biomarkers for diagnosis and risk stratification of autosomal dominant polycystic kidney disease: a multicentric study. PLoS One (2013) 1.12
Identification of a unique urinary biomarker profile in patients with autosomal dominant polycystic kidney disease. Kidney Int (2009) 1.12
Discovery of biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis coupled to mass spectrometry: towards new diagnostic and therapeutic approaches. Electrophoresis (2005) 1.12
Identification of urinary protein pattern in type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysis. J Diabetes Complications (2005) 1.12
Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy. PLoS One (2010) 1.12
Comprehensive human urine standards for comparability and standardization in clinical proteome analysis. Proteomics Clin Appl (2010) 1.12
Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. Gut (2012) 1.11
The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease. Proteomics (2009) 1.11
Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha. J Biol Chem (2003) 1.11
Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury. Kidney Int (2010) 1.10
Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals. J Hypertens (2010) 1.09
High-precision FLIM-FRET in fixed and living cells reveals heterogeneity in a simple CFP-YFP fusion protein. Biophys Chem (2007) 1.08