Published in J Biol Chem on November 19, 2008
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Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol (2006) 2.09
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Structural and functional analysis of SGT1 reveals that its interaction with HSP90 is required for the accumulation of Rx, an R protein involved in plant immunity. Plant Cell (2007) 1.51
Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae. EMBO J (2004) 1.39
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Naf1p, an essential nucleoplasmic factor specifically required for accumulation of box H/ACA small nucleolar RNPs. Mol Cell Biol (2002) 1.36
Structural and functional characterization of human telomerase RNA processing and cajal body localization signals. Mol Cell (2007) 1.35
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H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A (2007) 1.19
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The hsp90 molecular chaperone modulates multiple telomerase activities. Mol Cell Biol (2007) 1.08
Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants. EMBO Rep (2008) 1.01
Localization of sites of interaction between p23 and Hsp90 in solution. J Biol Chem (2006) 1.01
The box H/ACA RNP assembly factor Naf1p contains a domain homologous to Gar1p mediating its interaction with Cbf5p. J Mol Biol (2007) 0.99
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Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 7.29
The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science (2008) 4.94
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet (2004) 4.20
Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function. Mol Cell (2005) 3.16
Atomic view of a toxic amyloid small oligomer. Science (2012) 3.13
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating. Proc Natl Acad Sci U S A (2008) 2.82
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. Proc Natl Acad Sci U S A (2003) 2.18
Structure and function of telomerase RNA. Curr Opin Struct Biol (2006) 2.09
Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci (2007) 2.01
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci (2010) 1.95
Molecular mechanisms for protein-encoded inheritance. Nat Struct Mol Biol (2009) 1.94
Architecture of human telomerase RNA. Proc Natl Acad Sci U S A (2011) 1.93
Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin). Protein Sci (2008) 1.89
Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme. Protein Sci (2007) 1.87
RNAse III-mediated degradation of unspliced pre-mRNAs and lariat introns. Mol Cell (2003) 1.83
New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes. J Biomol NMR (2004) 1.81
Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions. J Mol Biol (2002) 1.79
Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A (2011) 1.76
Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA. Mol Cell (2009) 1.73
Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs. Structure (2011) 1.69
Structural origin of weakly ordered nitroxide motion in spin-labeled proteins. Protein Sci (2009) 1.68
DNA A-tract bending in three dimensions: solving the dA4T4 vs. dT4A4 conundrum. Proc Natl Acad Sci U S A (2004) 1.66
Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III. Proc Natl Acad Sci U S A (2004) 1.66
Site-directed spin labeling of a genetically encoded unnatural amino acid. Proc Natl Acad Sci U S A (2009) 1.65
Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol (2006) 1.61
Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation. Channels (Austin) (2009) 1.57
Structural determinants for the binding of ubiquitin-like domains to the proteasome. EMBO J (2003) 1.56
The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes Dev (2010) 1.55
The crystal structure of a cyanobacterial water-soluble carotenoid binding protein. Structure (2003) 1.54
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. J Mol Biol (2011) 1.53
Specificity of the interaction between ubiquitin-associated domains and ubiquitin. J Biol Chem (2004) 1.52
Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis. J Biol Chem (2008) 1.49
Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J Mol Biol (2004) 1.43
The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif. J Biol Chem (2006) 1.42
The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis. Proc Natl Acad Sci U S A (2007) 1.41
Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy. Proc Natl Acad Sci U S A (2011) 1.41
Structure of a 16-nm cage designed by using protein oligomers. Science (2012) 1.40
The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding. J Mol Biol (2002) 1.39
Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA. J Mol Biol (2008) 1.39
Monitoring RNA base structure and dynamics using site-directed spin labeling. Biochemistry (2003) 1.36
Structural and functional characterization of human telomerase RNA processing and cajal body localization signals. Mol Cell (2007) 1.35
An approach to crystallizing proteins by synthetic symmetrization. Proc Natl Acad Sci U S A (2006) 1.33
The architecture of Tetrahymena telomerase holoenzyme. Nature (2013) 1.32
Crystal structure of the excisionase-DNA complex from bacteriophage lambda. J Mol Biol (2004) 1.31
Granulysin crystal structure and a structure-derived lytic mechanism. J Mol Biol (2003) 1.30
The Shq1p.Naf1p complex is required for box H/ACA small nucleolar ribonucleoprotein particle biogenesis. J Biol Chem (2002) 1.30
Cotranscriptional recruitment of the pseudouridylsynthetase Cbf5p and of the RNA binding protein Naf1p during H/ACA snoRNP assembly. Mol Cell Biol (2005) 1.26
Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J Biol Chem (2005) 1.26
Multiple RNA surveillance pathways limit aberrant expression of iron uptake mRNAs and prevent iron toxicity in S. cerevisiae. Mol Cell (2005) 1.24
Structural insight into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. J Biol Chem (2010) 1.24
Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA. Proc Natl Acad Sci U S A (2010) 1.22
H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A (2007) 1.19
Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. RNA (2006) 1.17
Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure (2005) 1.16
Structure of the dimerization domain of DiGeorge critical region 8. Protein Sci (2010) 1.16
Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics. J Am Chem Soc (2011) 1.13
The roles of endonucleolytic cleavage and exonucleolytic digestion in the 5'-end processing of S. cerevisiae box C/D snoRNAs. RNA (2003) 1.13
Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1. J Biol Chem (2007) 1.12
Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic Acids Res (2013) 1.11
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity. Proc Natl Acad Sci U S A (2014) 1.11
Structure of the cooperative Xis-DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly. Proc Natl Acad Sci U S A (2007) 1.11
A web-based comparative genomics tutorial for investigating microbial genomes. Microbiol Educ (2004) 1.11
Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo. Proc Natl Acad Sci U S A (2013) 1.08
Fis targets assembly of the Xis nucleoprotein filament to promote excisive recombination by phage lambda. J Mol Biol (2007) 1.06
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J Mol Biol (2004) 1.06
Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell (2012) 1.06
Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J Mol Biol (2007) 1.06
Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain. EMBO J (2010) 1.06
Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. J Mol Biol (2005) 1.05
The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Sci (2012) 1.05
Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res (2010) 1.04
Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J Biol Chem (2010) 1.01
Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA. RNA (2006) 1.00
Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control. RNA (2011) 1.00
YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA. RNA (2003) 1.00
Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins. Protein Sci (2013) 0.99
Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element. Nucleic Acids Res (2006) 0.98
An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci (2011) 0.98
Structural determinants for ligand capture by a class II preQ1 riboswitch. Proc Natl Acad Sci U S A (2014) 0.98
Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain. Angew Chem Int Ed Engl (2012) 0.96
Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome. Nucleic Acids Res (2002) 0.95
Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophys Chem (2003) 0.95
The crystal structure of the Mycobacterium tuberculosis Rv3019c-Rv3020c ESX complex reveals a domain-swapped heterotetramer. Protein Sci (2010) 0.94
Atomic structures suggest determinants of transmission barriers in mammalian prion disease. Biochemistry (2011) 0.93
Structural and functional studies of γ-carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium. J Mol Biol (2013) 0.93
A cotranscriptional model for 3'-end processing of the Saccharomyces cerevisiae pre-ribosomal RNA precursor. RNA (2004) 0.93
Synthesis, structure, and metalation of two new highly porous zirconium metal-organic frameworks. Inorg Chem (2012) 0.92
Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae. FEBS J (2005) 0.92
Structure determination of protein/RNA complexes by NMR. Methods Enzymol (2005) 0.91
Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function. Nucleic Acids Res (2013) 0.91
Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR. J Am Chem Soc (2005) 0.90
Structure and identification of a pterin dehydratase-like protein as a ribulose-bisphosphate carboxylase/oxygenase (RuBisCO) assembly factor in the α-carboxysome. J Biol Chem (2014) 0.90
Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub. Mol Cell Biol (2013) 0.90
Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr D Biol Crystallogr (2002) 0.90
Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II). Biochemistry (2002) 0.89