Published in J Biomed Opt on November 21, 2008
Near-infrared fluorescent proteins. Nat Methods (2010) 2.52
A rapidly maturing far-red derivative of DsRed-Express2 for whole-cell labeling. Biochemistry (2009) 2.12
A photoswitchable orange-to-far-red fluorescent protein, PSmOrange. Nat Methods (2011) 1.69
FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography. Nat Methods (2012) 1.44
Red fluorescent proteins: advanced imaging applications and future design. Angew Chem Int Ed Engl (2012) 1.25
From seeing to believing: labelling strategies for in vivo cell-tracking experiments. Interface Focus (2013) 1.17
An Improved BAC Transgenic Fluorescent Reporter Line for Sensitive and Specific Identification of Striatonigral Medium Spiny Neurons. Front Syst Neurosci (2011) 1.15
In vivo optical imaging and dynamic contrast methods for biomedical research. Philos Trans A Math Phys Eng Sci (2011) 1.08
Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett (2009) 1.07
A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging. J Antimicrob Chemother (2012) 1.02
In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast. Cancer Res (2015) 1.01
In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express (2011) 1.00
Excitation spectroscopy in multispectral optical fluorescence tomography: methodology, feasibility and computer simulation studies. Phys Med Biol (2009) 0.99
Recombinant canine distemper virus strain Snyder Hill expressing green or red fluorescent proteins causes meningoencephalitis in the ferret. J Virol (2012) 0.88
A novel luciferase fusion protein for highly sensitive optical imaging: from single-cell analysis to in vivo whole-body bioluminescence imaging. Anal Bioanal Chem (2014) 0.87
Beyond the rainbow: new fluorescent proteins brighten the infrared scene. Nat Methods (2011) 0.87
In vivo monitoring of adult neurogenesis in health and disease. Front Neurosci (2011) 0.87
A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins. Oncotarget (2015) 0.85
Cytokine reporter mice in immunological research: perspectives and lessons learned. Immunology (2010) 0.85
An orthotopic model of serous ovarian cancer in immunocompetent mice for in vivo tumor imaging and monitoring of tumor immune responses. J Vis Exp (2010) 0.84
Development and application of reporter-expressing mononegaviruses: current challenges and perspectives. Antiviral Res (2014) 0.83
Preclinical whole body time domain fluorescence lifetime multiplexing of fluorescent proteins. J Biomed Opt (2014) 0.82
Genetically Targeted All-Optical Electrophysiology with a Transgenic Cre-Dependent Optopatch Mouse. J Neurosci (2016) 0.80
A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes. PLoS One (2013) 0.80
Fiber optic microendoscopy for preclinical study of bacterial infection dynamics. Biomed Opt Express (2011) 0.80
Self-illuminating quantum dots for non-invasive bioluminescence imaging of mammalian gametes. J Nanobiotechnology (2015) 0.80
Mass spectrometric imaging of red fluorescent protein in breast tumor xenografts. J Am Soc Mass Spectrom (2012) 0.79
In vivo fluorescence imaging and urinary monoamines as surrogate biomarkers of disease progression in a mouse model of pheochromocytoma. Endocrinology (2014) 0.78
In Vivo Imaging of Far-red Fluorescent Proteins after DNA Electrotransfer to Muscle Tissue. Biol Proced Online (2009) 0.77
Molecular Imaging Probe Development using Microfluidics. Curr Org Synth (2011) 0.76
Usefulness of a Darwinian system in a biotechnological application: evolution of optical window fluorescent protein variants under selective pressure. PLoS One (2014) 0.76
A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging. PLoS One (2015) 0.76
Performance of computer vision in vivo flow cytometry with low fluorescence contrast. J Biomed Opt (2015) 0.75
A Novel Reporter Rat Strain That Conditionally Expresses the Bright Red Fluorescent Protein tdTomato. PLoS One (2016) 0.75
Formulation of image fusion as a constrained least squares optimization problem. J Med Imaging (Bellingham) (2017) 0.75
MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter. Nat Biotechnol (2016) 0.75
Far-red fluorescent cell line for preclinical study of HER2-targeted agents. Dokl Biochem Biophys (2016) 0.75
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol (2004) 36.25
Deep tissue two-photon microscopy. Nat Methods (2005) 14.95
Shedding light onto live molecular targets. Nat Med (2003) 8.47
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol (1999) 8.46
Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy. Biophys J (1997) 6.26
The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer (2005) 5.83
Bright far-red fluorescent protein for whole-body imaging. Nat Methods (2007) 5.68
Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci U S A (2004) 4.37
Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer (2002) 3.96
Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol Rev (2005) 3.27
Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A (2000) 3.24
Optimized large-scale production of high titer lentivirus vector pseudotypes. J Virol Methods (2004) 2.84
Absorption spectra of human fetal and adult oxyhemoglobin, de-oxyhemoglobin, carboxyhemoglobin, and methemoglobin. Clin Chem (1991) 2.52
In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus. Nat Med (2006) 2.27
Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A (2005) 2.16
Intrinsic fluorescence spectroscopy in turbid media: disentangling effects of scattering and absorption. Appl Opt (2001) 1.98
A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. J Surg Res (2003) 1.82
Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncol (2002) 1.67
Near-infrared fluorescence optical imaging and tomography. Dis Markers (2004) 1.51
Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer. Neoplasia (2006) 1.45
Molecular imaging of gene therapy for cancer. Gene Ther (2004) 1.28
Planar fluorescence imaging using normalized data. J Biomed Opt (2006) 1.27
Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors. Proc Natl Acad Sci U S A (2001) 1.26
Normalized transillumination of fluorescent proteins in small animals. Mol Imaging (2006) 1.07
From finite to infinite volumes: removal of boundaries in diffuse wave imaging. Phys Rev Lett (2006) 0.98
Presenting antigen presentation in living cells using biophysical techniques. Curr Opin Microbiol (2005) 0.81
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 11.51
Shedding light onto live molecular targets. Nat Med (2003) 8.47
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med (2011) 7.82
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol (2008) 5.21
A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods (2008) 3.31
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res (2007) 2.90
Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res (2009) 2.74
A highly sensitive assay for monitoring the secretory pathway and ER stress. PLoS One (2007) 2.63
In vivo imaging of proteolytic activity in atherosclerosis. Circulation (2002) 2.62
A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Med Phys (2003) 2.58
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell (2008) 2.57
Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Circulation (2006) 2.56
Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation (2008) 2.52
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A (2009) 2.47
Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo. Nat Med (2011) 2.44
Real-time intraoperative fluorescence imaging system using light-absorption correction. J Biomed Opt (2010) 2.34
Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo. Circulation (2007) 2.19
Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A (2005) 2.16
Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio. IEEE Trans Med Imaging (2005) 2.15
Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy. Brain (2014) 2.14
Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Mol Cell Biol (2009) 2.06
Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett (2007) 2.04
Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A (2008) 2.00
Human glioma growth is controlled by microRNA-10b. Cancer Res (2011) 1.96
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell (2010) 1.94
miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. Oncotarget (2010) 1.92
Identification of genes conferring resistance to 5-fluorouracil. Proc Natl Acad Sci U S A (2009) 1.92
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer. Proc Natl Acad Sci U S A (2005) 1.91
Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett (2007) 1.91
Tomographic fluorescence mapping of tumor targets. Cancer Res (2005) 1.89
In vivo tracking of neural progenitor cell migration to glioblastomas. Hum Gene Ther (2003) 1.89
Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging. Part Fibre Toxicol (2010) 1.89
Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas. Nat Neurosci (2011) 1.84
Optical-based molecular imaging: contrast agents and potential medical applications. Eur Radiol (2002) 1.83
Optical imaging of cancer heterogeneity with multispectral optoacoustic tomography. Radiology (2012) 1.81
In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods (2007) 1.78
Volumetric real-time multispectral optoacoustic tomography of biomarkers. Nat Protoc (2011) 1.78
Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography. J Opt Soc Am A Opt Image Sci Vis (2004) 1.65
Molecular mechanism of chemoresistance by astrocyte elevated gene-1. Cancer Res (2010) 1.64
Intraoperative near-infrared fluorescence tumor imaging with vascular endothelial growth factor and human epidermal growth factor receptor 2 targeting antibodies. J Nucl Med (2011) 1.62
Experimental fluorescence tomography of tissues with noncontact measurements. IEEE Trans Med Imaging (2004) 1.62
Hybrid system for simultaneous fluorescence and x-ray computed tomography. IEEE Trans Med Imaging (2009) 1.62
Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip (2009) 1.61
Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. J Am Coll Cardiol (2011) 1.60
Bioluminescence imaging: progress and applications. Trends Biotechnol (2011) 1.59
Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques. Sci Transl Med (2011) 1.54
Fast semi-analytical model-based acoustic inversion for quantitative optoacoustic tomography. IEEE Trans Med Imaging (2010) 1.52
Multispectral imaging using multiple-bandpass filters. Opt Lett (2008) 1.52
Microvesicle-associated AAV vector as a novel gene delivery system. Mol Ther (2012) 1.49
TRAIL on trial: preclinical advances in cancer therapy. Trends Mol Med (2013) 1.49
Time-resolved imaging of optical coefficients through murine chest cavities. J Biomed Opt (2007) 1.46
Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology (2007) 1.45
FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography. Nat Methods (2012) 1.44
Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques. J Biomed Opt (2010) 1.42
In vivo imaging of beta-galactosidase activity using far red fluorescent switch. Cancer Res (2004) 1.41
Intraoperative multispectral fluorescence imaging for the detection of the sentinel lymph node in cervical cancer: a novel concept. Mol Imaging Biol (2011) 1.41
Astrocyte elevated gene-1: a novel target for human glioma therapy. Mol Cancer Ther (2010) 1.39
Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases. PLoS One (2009) 1.37
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci (2008) 1.36
High-sensitivity compact ultrasonic detector based on a pi-phase-shifted fiber Bragg grating. Opt Lett (2011) 1.35
Gaussia luciferase variant for high-throughput functional screening applications. Anal Chem (2009) 1.35
Fluorescent protein tomography scanner for small animal imaging. IEEE Trans Med Imaging (2005) 1.34
Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL. Neoplasia (2007) 1.33
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model. Hepatology (2012) 1.32
Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging. Opt Express (2009) 1.30
Real-time imaging of cardiovascular dynamics and circulating gold nanorods with multispectral optoacoustic tomography. Opt Express (2010) 1.30
Complete-angle projection diffuse optical tomography by use of early photons. Opt Lett (2005) 1.30
Free-space propagation of diffuse light: theory and experiments. Phys Rev Lett (2003) 1.28
Imaging of stem cell recruitment to ischemic infarcts in a murine model. Stroke (2004) 1.28
Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice. Radiology (2003) 1.28
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models. Cancer Res (2010) 1.28
Compressive sensing for biomedical imaging. IEEE Trans Med Imaging (2011) 1.27
Video rate optoacoustic tomography of mouse kidney perfusion. Opt Lett (2010) 1.25
Noncontact optical imaging in mice with full angular coverage and automatic surface extraction. Appl Opt (2007) 1.23
Fluorescence fluctuation analysis of Arabidopsis thaliana somatic embryogenesis receptor-like kinase and brassinosteroid insensitive 1 receptor oligomerization. Biophys J (2007) 1.23
Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest Radiol (2005) 1.22
Multispectral optoacoustic tomography of matrix metalloproteinase activity in vulnerable human carotid plaques. Mol Imaging Biol (2012) 1.22
Mutant sodium channel for tumor therapy. Mol Ther (2009) 1.22
Development of fluorescent materials for Diffuse Fluorescence Tomography standards and phantoms. Opt Express (2007) 1.22
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare. Lancet Oncol (2008) 1.20
Performance dependence of hybrid x-ray computed tomography/fluorescence molecular tomography on the optical forward problem. J Opt Soc Am A Opt Image Sci Vis (2009) 1.20
Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep (2012) 1.19
Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys (2007) 1.19
Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett (2002) 1.19
Optimization of 360 degrees projection fluorescence molecular tomography. Med Image Anal (2007) 1.18
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther (2008) 1.18
Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy. Neoplasia (2003) 1.18
Brain cancer stem cells. J Mol Med (Berl) (2009) 1.18
Normalized Born ratio for fluorescence optical projection tomography. Opt Lett (2009) 1.17
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther (2008) 1.16
Fluorescence molecular tomography in the presence of background fluorescence. Phys Med Biol (2006) 1.16
Noncontact optical tomography of turbid media. Opt Lett (2003) 1.16
Three-dimensional optoacoustic tomography using a conventional ultrasound linear detector array: whole-body tomographic system for small animals. Med Phys (2013) 1.16
Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging (2007) 1.15
Real-time handheld multispectral optoacoustic imaging. Opt Lett (2013) 1.15