Published in J Am Soc Mass Spectrom on November 27, 2012
Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer. Proc Natl Acad Sci U S A (2014) 1.02
MALDI-Mass Spectrometric Imaging Revealing Hypoxia-Driven Lipids and Proteins in a Breast Tumor Model. Anal Chem (2015) 0.83
Choline metabolism-based molecular diagnosis of cancer: an update. Expert Rev Mol Diagn (2015) 0.81
Emerging proteomic technologies for elucidating context-dependent cellular signaling events: A big challenge of tiny proportions. Proteomics (2015) 0.76
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol (2004) 36.25
A monomeric red fluorescent protein. Proc Natl Acad Sci U S A (2002) 21.56
Fluorescent proteins from nonbioluminescent Anthozoa species. Nat Biotechnol (1999) 14.64
Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral. Proc Natl Acad Sci U S A (2000) 7.68
The structure of the chromophore within DsRed, a red fluorescent protein from coral. Proc Natl Acad Sci U S A (2000) 5.88
Mass spectrometric imaging for biomedical tissue analysis. Chem Rev (2010) 2.51
Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt (2008) 1.93
Refolding and oriented insertion of a membrane protein into a lipid bilayer. Proc Natl Acad Sci U S A (1992) 1.86
Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer. Neoplasia (2006) 1.45
Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model. Cancer Res (2006) 1.41
Spontaneous oligomerization of a staphylococcal alpha-hemolysin conformationally constrained by removal of residues that form the transmembrane beta-barrel. Protein Eng (1997) 1.36
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer. PLoS One (2012) 1.25
Green fluorescent protein rendered susceptible to proteolysis: positions for protease-sensitive insertions. Arch Biochem Biophys (2001) 1.00
Fiducial markers for combined 3-dimensional mass spectrometric and optical tissue imaging. Anal Chem (2012) 0.94
Localized hypoxia results in spatially heterogeneous metabolic signatures in breast tumor models. Neoplasia (2012) 0.93
Combined MR, fluorescence and histology imaging strategy in a human breast tumor xenograft model. NMR Biomed (2012) 0.86
TdTomato and EGFP identification in histological sections: insight and alternatives. Biotech Histochem (2010) 0.84
Mass spectrometry-based structural dissection of fluorescent proteins. Biochemistry (2009) 0.78
HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell (2007) 4.81
Artificial reporter gene providing MRI contrast based on proton exchange. Nat Biotechnol (2007) 3.87
Imaging mass spectrometry. Mass Spectrom Rev (2007) 3.79
MRI of the tumor microenvironment. J Magn Reson Imaging (2002) 2.87
Choline metabolism in malignant transformation. Nat Rev Cancer (2011) 2.85
Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene (2003) 2.71
Mass spectrometric imaging for biomedical tissue analysis. Chem Rev (2010) 2.51
Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res (2004) 2.43
Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer. Cancer Res (2005) 2.32
Essential role for proteinase-activated receptor-2 in arthritis. J Clin Invest (2003) 2.22
Choline phospholipid metabolism: a target in cancer cells? J Cell Biochem (2003) 2.12
Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer. Biochem Biophys Res Commun (2007) 2.06
Magnetic resonance molecular imaging of the HER-2/neu receptor. Cancer Res (2003) 2.05
Analysis of copy number variations among diverse cattle breeds. Genome Res (2010) 2.02
A concise review of mass spectrometry imaging. J Chromatogr A (2010) 2.01
MicroRNA-138 suppresses invasion and promotes apoptosis in head and neck squamous cell carcinoma cell lines. Cancer Lett (2009) 1.92
Comparative analysis of Alu repeats in primate genomes. Genome Res (2009) 1.85
Natural D-glucose as a biodegradable MRI contrast agent for detecting cancer. Magn Reson Med (2012) 1.84
Monitoring macromolecular complexes involved in the chaperonin-assisted protein folding cycle by mass spectrometry. Nat Methods (2005) 1.79
RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation. Cancer Res (2005) 1.77
MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles. Magn Reson Med (2003) 1.76
Systematic evaluation of antioxidant capacities of the ethanolic extract of different tissues of jujube (Ziziphus jujuba Mill.) from China. Food Chem Toxicol (2010) 1.73
Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Anal Chem (2006) 1.71
Developing MR reporter genes: promises and pitfalls. NMR Biomed (2007) 1.70
Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia (2004) 1.70
Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells. Cancer Res (2010) 1.65
Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression. Neoplasia (2009) 1.60
MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics (2009) 1.55
Choline metabolism in cancer: implications for diagnosis and therapy. Expert Rev Mol Diagn (2006) 1.54
Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. Cancer Res (2008) 1.52
Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry. Anal Chem (2005) 1.46
Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer. Neoplasia (2006) 1.45
Imaging of peptides in the rat brain using MALDI-FTICR mass spectrometry. J Am Soc Mass Spectrom (2006) 1.42
imzML--a common data format for the flexible exchange and processing of mass spectrometry imaging data. J Proteomics (2012) 1.42
Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model. Cancer Res (2006) 1.41
Unique penetrance of hearing loss in a five-generation Chinese family with the mitochondrial 12S rRNA 1555A > G mutation. Acta Otolaryngol (2011) 1.40
Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions. Mol Pharm (2006) 1.37
Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography. Cancer Res (2010) 1.32
Sample preparation issues for tissue imaging by imaging MS. Proteomics (2009) 1.29
The transcription factor encyclopedia. Genome Biol (2012) 1.28
Self-assembled three dimensional radio frequency (RF) shielded containers for cell encapsulation. Biomed Microdevices (2005) 1.28
Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells. Cancer Res (2007) 1.27
Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft. Cancer Res (2009) 1.27
High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface. Anal Chem (2004) 1.26
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer. PLoS One (2012) 1.25
The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. Proc Natl Acad Sci U S A (2011) 1.24
On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry. J Am Soc Mass Spectrom (2009) 1.23
Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.22
Tandem mass spectrometry of intact GroEL-substrate complexes reveals substrate-specific conformational changes in the trans ring. J Am Chem Soc (2006) 1.22
Metabolic tumor imaging using magnetic resonance spectroscopy. Semin Oncol (2011) 1.22
Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard. Anal Chem (2012) 1.21
Metabolomics of cancer. Methods Mol Biol (2009) 1.21
HOXA5-twist interaction alters p53 homeostasis in breast cancer cells. J Biol Chem (2004) 1.19
Magnetic resonance imaging of cell surface receptors using targeted contrast agents. Curr Pharm Biotechnol (2004) 1.17
Subcellular imaging mass spectrometry of brain tissue. J Mass Spectrom (2005) 1.16
Imaging mass spectrometry at cellular length scales. Nat Protoc (2007) 1.15
Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging. Cancer Res (2005) 1.15
Silencing of cyclooxygenase-2 inhibits metastasis and delays tumor onset of poorly differentiated metastatic breast cancer cells. Mol Cancer Res (2007) 1.14
PAMAM dendrimer-based contrast agents for MR imaging of Her-2/neu receptors by a three-step pretargeting approach. Magn Reson Med (2008) 1.13
NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Cytokine (2008) 1.12
Hypoxic tumor microenvironments reduce collagen I fiber density. Neoplasia (2010) 1.12
Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. Carcinogenesis (2010) 1.12
Comparative proteomics approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics (2008) 1.11
Realistic modeling of ion cloud motion in a Fourier transform ion cyclotron resonance cell by use of a particle-in-cell approach. Rapid Commun Mass Spectrom (2007) 1.10
Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts. Neoplasia (2009) 1.10
Effect of local matrix crystal variations in matrix-assisted ionization techniques for mass spectrometry. Anal Chem (2003) 1.09
Literacy promotion for families participating in the women, infants and children program. Pediatrics (2011) 1.09
Combined dynamic contrast enhanced breast MR and proton spectroscopic imaging: a feasibility study. J Magn Reson Imaging (2005) 1.08
Collagen I fiber density increases in lymph node positive breast cancers: pilot study. J Biomed Opt (2012) 1.08
Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide. PLoS One (2011) 1.07
Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer. Chem Rev (2010) 1.06
Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models. Cancer Res (2010) 1.06
Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models. J Lipid Res (2012) 1.04