Published in Autophagy on January 23, 2009
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The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation. Proc Natl Acad Sci U S A (2014) 0.99
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy. Autophagy (2012) 0.99
Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma. Clin Epigenetics (2013) 0.98
Lithium treatment increases endothelial cell survival and autophagy in a mouse model of Fuchs endothelial corneal dystrophy. Br J Ophthalmol (2013) 0.90
Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. Elife (2017) 0.88
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy. Invest Ophthalmol Vis Sci (2013) 0.88
Techniques to study autophagy in plants. Int J Plant Genomics (2009) 0.85
Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases. Inflamm Bowel Dis (2010) 0.83
TM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cells. Oncogene (2015) 0.80
Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration. BMC Genomics (2015) 0.80
Conserved function of the lysine-based KXD/E motif in Golgi retention for endomembrane proteins among different organisms. Mol Biol Cell (2015) 0.79
Comparative analysis of nonaspanin protein sequences and expression studies in zebrafish. Immunogenetics (2010) 0.79
PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1. Autophagy (2014) 0.78
Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene (2015) 0.78
DHRSX, a novel non-classical secretory protein associated with starvation induced autophagy. Int J Med Sci (2014) 0.76
Homozygosity mapping and sequencing identify two genes that might contribute to pointing behavior in hunting dogs. Canine Genet Epidemiol (2015) 0.75
Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells. PLoS One (2015) 0.75
MARCH2 regulates autophagy by promoting CFTR ubiquitination and degradation and PIK3CA-AKT-MTOR signaling. Autophagy (2016) 0.75
SZRD1 is a Novel Protein that Functions as a Potential Tumor Suppressor in Cervical Cancer. J Cancer (2017) 0.75
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science (2011) 3.49
Design and implementation of a secure wireless mote-based medical sensor network. Sensors (Basel) (2009) 2.83
HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infect Dis (2013) 2.82
Dysregulation of HSG triggers vascular proliferative disorders. Nat Cell Biol (2004) 2.75
Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. J Biol Chem (2005) 2.68
JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell (2011) 2.56
Hepatitis C virus infection in former commercial plasma/blood donors in rural Shanxi Province, China: the China Integrated Programs for Research on AIDS. J Infect Dis (2005) 2.47
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A (2012) 2.27
Risk Factors Associated with Left-Sided Cardiac Valve Calcification: A Case Control Study. Cardiology (2016) 2.04
Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy. J Gastroenterol (2015) 2.01
Phytochrome-interacting factor 4 (PIF4) regulates auxin biosynthesis at high temperature. Proc Natl Acad Sci U S A (2011) 2.00
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. ACS Chem Biol (2006) 1.97
All in the family: the impact of caring for grandchildren on grandparents' health. J Gerontol B Psychol Sci Soc Sci (2007) 1.97
Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua. Science (2011) 1.96
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature (2013) 1.86
The development of HIV/AIDS surveillance in China. AIDS (2007) 1.86
Sam68 up-regulation correlates with, and its down-regulation inhibits, proliferation and tumourigenicity of breast cancer cells. J Pathol (2010) 1.82
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage (2009) 1.72
A radar-enabled collaborative sensor network integrating COTS technology for surveillance and tracking. Sensors (Basel) (2012) 1.65
PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol Biol Cell (2007) 1.61
Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. ACS Chem Biol (2009) 1.60
Intimate partner violence in China: national prevalence, risk factors and associated health problems. Int Fam Plan Perspect (2004) 1.59
Evaluation of the human transmission risk of an atypical bovine spongiform encephalopathy prion strain. J Virol (2008) 1.59
Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway. Am J Pathol (2009) 1.54
Hybrid male sterility in rice controlled by interaction between divergent alleles of two adjacent genes. Proc Natl Acad Sci U S A (2008) 1.52
MicroRNAs in osteosarcoma: diagnostic and therapeutic aspects. Tumour Biol (2013) 1.52
Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells. Cancer Res (2005) 1.51
Collaborative computational anatomy: an MRI morphometry study of the human brain via diffeomorphic metric mapping. Hum Brain Mapp (2009) 1.50
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders. Cell (2013) 1.49
A sequence-based survey of the complex structural organization of tumor genomes. Genome Biol (2008) 1.45
Local Rank Inference for Varying Coefficient Models. J Am Stat Assoc (2009) 1.45
Optimization of local methylprednisolone delivery to inhibit inflammatory reaction and neointimal hyperplasia of coated coronary stents. J Invasive Cardiol (2002) 1.44
Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China. Ann Occup Hyg (2004) 1.44
Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers. Cancer Res (2005) 1.42
Prevalence of HIV infection and predictors for syphilis infection among female sex workers in southern China. Southeast Asian J Trop Med Public Health (2009) 1.42
Allogeneic periodontal ligament stem cell therapy for periodontitis in swine. Stem Cells (2010) 1.40
An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression. J Cell Sci (2004) 1.39
Gender-specific response to isoflurane preconditioning in focal cerebral ischemia. J Cereb Blood Flow Metab (2007) 1.38
Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3K/Akt/NF-κB pathway in human non-small cell lung cancer. Clin Cancer Res (2011) 1.38
Integrative genomic analysis of the human immune response to influenza vaccination. Elife (2013) 1.37
Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis. PLoS Med (2006) 1.36
No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo. Diabetes (2004) 1.35
Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses. J Allergy Clin Immunol (2011) 1.34
Sub-retinal drusenoid deposits in human retina: organization and composition. Exp Eye Res (2008) 1.33
The cerebral microvasculature in schizophrenia: a laser capture microdissection study. PLoS One (2008) 1.29
A cell-permeable synthetic transcription factor mimic. Angew Chem Int Ed Engl (2007) 1.29
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor. Nat Struct Biol (2002) 1.27
Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). J Med Chem (2012) 1.27
CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Res (2009) 1.27
Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy. Exp Eye Res (2011) 1.25
Tracking the evolution of HIV/AIDS in China from 1989-2009 to inform future prevention and control efforts. PLoS One (2011) 1.22
Widening social inequalities in risk for sudden infant death syndrome. Am J Public Health (2005) 1.21
Secreted protein prediction system combining CJ-SPHMM, TMHMM, and PSORT. Mamm Genome (2003) 1.19
Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism. Blood (2004) 1.19
Nested genes in the human genome. Genomics (2005) 1.18
Design and synthesis of a cell-permeable synthetic transcription factor mimic. J Comb Chem (2007) 1.17
TGF-beta- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling. Am J Physiol Heart Circ Physiol (2007) 1.16
TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis. Apoptosis (2007) 1.14
T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci U S A (2011) 1.13
Low temperatures induce rapid changes in chromatin state and transcript levels of the cereal VERNALIZATION1 gene. J Exp Bot (2013) 1.12
An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant (2007) 1.12
IL-35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells. Biochem Biophys Res Commun (2012) 1.12
Low histologic grade follicular lymphoma with high proliferation index: morphologic and clinical features. Am J Surg Pathol (2005) 1.11
Development of new microsatellite DNA markers from Apostichopus japonicus and their cross-species application in Parastichopus parvimensis and Pathallus mollis. Int J Mol Sci (2011) 1.10
Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells. Mol Cancer Res (2009) 1.10
High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg Med Chem (2008) 1.09
VSTM1-v2, a novel soluble glycoprotein, promotes the differentiation and activation of Th17 cells. Cell Immunol (2012) 1.09
Canadian perspectives in glaucoma management: setting target intraocular pressure range. Can J Ophthalmol (2003) 1.08
2-(4-Fluoro-benzyl-idene)-N-(4-meth-oxy-benzylidene)-1,3,4-thia-diazol-2-amine. Acta Crystallogr Sect E Struct Rep Online (2010) 1.08
High responsivity photoconductors based on iron pyrite nanowires using sulfurization of anodized iron oxide nanotubes. Nano Lett (2014) 1.08
Coronary artery bypass surgery provokes Alzheimer's disease-like changes in the cerebrospinal fluid. J Alzheimers Dis (2010) 1.06
[Epidemic characteristics of HIV/AIDS among men who have sex with men from 2006 to 2010 in China]. Zhonghua Liu Xing Bing Xue Za Zhi (2012) 1.06
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. Neoplasia (2009) 1.06
Controlling the morphology of electrospray-generated PLGA microparticles for drug delivery. J Colloid Interface Sci (2009) 1.06
[Comparative studies on pharmacological effects of angong niuhuang pill with its simplified prescicription]. Zhongguo Zhong Yao Za Zhi (2003) 1.05
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches. Front Med (2012) 1.05
Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Genomics (2003) 1.04
BNC Protects H9c2 Cardiomyoblasts from H 2 O 2 -Induced Oxidative Injury through ERK1/2 Signaling Pathway. Evid Based Complement Alternat Med (2013) 1.04
Identification of metastasis-related proteins and their clinical relevance to triple-negative human breast cancer. Clin Cancer Res (2008) 1.03
Microarray analysis of differential gene expression in temporomandibular joint condylar cartilage after experimentally induced osteoarthritis. Osteoarthritis Cartilage (2005) 1.03
AC3-33, a novel secretory protein, inhibits Elk1 transcriptional activity via ERK pathway. Mol Biol Rep (2010) 1.03
Comparison of neuroimaging modalities for the prediction of conversion from mild cognitive impairment to Alzheimer's dementia. Neurobiol Aging (2013) 1.02
Isolation and characterization of coactivator-binding peptoids from a combinatorial library. Mol Biosyst (2006) 1.02
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Mol Biosyst (2007) 1.02
Regional differences in HIV prevalence among drug users in China: potential for future spread of HIV? BMC Infect Dis (2008) 1.02
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations. Blood (2011) 1.02
RhesusBase: a knowledgebase for the monkey research community. Nucleic Acids Res (2012) 1.02
Open-door laminoplasty with plate fixation at alternating levels for treatment of multilevel degenerative cervical disease. J Spinal Disord Tech (2013) 1.00
On-site variety discrimination of tomato plant using visible-near infrared reflectance spectroscopy. J Zhejiang Univ Sci B (2009) 1.00
Adenovirus-expressed human hyperplasia suppressor gene induces apoptosis in cancer cells. Mol Cancer Ther (2008) 1.00
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature (2013) 0.99
Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration. Hepatology (2009) 0.99
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy. Autophagy (2012) 0.99
Anti-breast cancer effects and mechanisms of Xihuang pill on human breast cancer cell lines. J Tradit Chin Med (2013) 0.98