Published in Autophagy on November 01, 2011
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
The machinery of macroautophagy. Cell Res (2013) 3.13
Canonical and non-canonical autophagy: variations on a common theme of self-eating? Nat Rev Mol Cell Biol (2011) 2.52
Autophagic processes in yeast: mechanism, machinery and regulation. Genetics (2013) 1.78
Developing a set of guidelines for your research field: a practical approach. Mol Biol Cell (2016) 1.44
Autophagy in the regulation of pathogen replication and adaptive immunity. Trends Immunol (2012) 1.21
Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Am J Physiol Heart Circ Physiol (2013) 1.12
Molecular mechanisms of autophagy in the cardiovascular system. Circ Res (2015) 1.10
The complex landscape of pancreatic cancer metabolism. Carcinogenesis (2014) 1.08
Ume6 transcription factor is part of a signaling cascade that regulates autophagy. Proc Natl Acad Sci U S A (2012) 1.08
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis. J Immunol (2013) 1.06
Programmed necrosis and autophagy in immune function. Immunol Rev (2012) 1.05
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy. Biol Chem (2013) 1.04
Features of autophagic cell death in Plasmodium liver-stage parasites. Autophagy (2013) 1.00
Targeting autophagy in breast cancer. World J Clin Oncol (2014) 0.99
Metabolic Dependencies in RAS-Driven Cancers. Clin Cancer Res (2015) 0.98
Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy (2013) 0.98
Phosphatidylinositol 4-kinases are required for autophagic membrane trafficking. J Biol Chem (2012) 0.96
Peroxisome degradation in mammals: mechanisms of action, recent advances, and perspectives. Front Physiol (2013) 0.96
Histone deacetylase inhibitors potentiate vesicular stomatitis virus oncolysis in prostate cancer cells by modulating NF-κB-dependent autophagy. J Virol (2013) 0.95
Androgens promote prostate cancer cell growth through induction of autophagy. Mol Endocrinol (2012) 0.95
Coming soon to a journal near you — the updated guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2014) 0.92
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy (2014) 0.87
Molecular events underlying Parkinson's disease - an interwoven tapestry. Front Neurol (2013) 0.86
Inhibition of human immunodeficiency virus type-1 through autophagy. Curr Opin Microbiol (2013) 0.85
Autophagy: mechanism and physiological relevance 'brewed' from yeast studies. Front Biosci (Schol Ed) (2012) 0.85
Autophagy in renal diseases. Pediatr Nephrol (2015) 0.85
The pleiotropic roles of sphingolipid signaling in autophagy. Cell Death Dis (2014) 0.84
HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy. PLoS One (2014) 0.84
Infection with Usutu virus induces an autophagic response in mammalian cells. PLoS Negl Trop Dis (2013) 0.83
Phosphorylation of Atg9 regulates movement to the phagophore assembly site and the rate of autophagosome formation. Autophagy (2016) 0.83
Ksp1 kinase regulates autophagy via the target of rapamycin complex 1 (TORC1) pathway. J Biol Chem (2012) 0.82
Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Autophagy (2015) 0.82
Functional role of autophagy in gastric cancer. Oncotarget (2016) 0.81
Look people, "Atg" is an abbreviation for "autophagy-related." That's it. Autophagy (2012) 0.81
Immunohistochemical and ultrastructural visualization of different routes of oocyte elimination in adult rats. Eur J Histochem (2012) 0.81
Co-delivery of Gefitinib and chloroquine by chitosan nanoparticles for overcoming the drug acquired resistance. J Nanobiotechnology (2015) 0.81
Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver. Am J Physiol Gastrointest Liver Physiol (2014) 0.81
Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. G3 (Bethesda) (2014) 0.81
Autophagy-inducing peptides from mammalian VSV and fish VHSV rhabdoviral G glycoproteins (G) as models for the development of new therapeutic molecules. Autophagy (2014) 0.80
Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases. World J Gastroenterol (2014) 0.80
The Role of Deoxycytidine Kinase (dCK) in Radiation-Induced Cell Death. Int J Mol Sci (2016) 0.78
Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose. Oncotarget (2015) 0.78
Implications of therapy-induced selective autophagy on tumor metabolism and survival. Int J Cell Biol (2012) 0.78
Connexins: substrates and regulators of autophagy. BMC Cell Biol (2016) 0.78
Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and microRNAs: Role in the Antibody Response. Front Immunol (2015) 0.77
Interactions between Autophagy and Bacterial Toxins: Targets for Therapy? Toxins (Basel) (2015) 0.77
Autophagy and Tumor Metabolism. Cell Metab (2017) 0.77
Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer. Cells (2012) 0.76
Chaperone-mediated autophagy in the kidney: the road more traveled. Semin Nephrol (2013) 0.76
Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins. Cells (2012) 0.76
Degradation-mediated protein quality control at the inner nuclear membrane. Nucleus (2016) 0.76
Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense. Sci Rep (2017) 0.75
Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci (2016) 0.75
Autophagy regulates odontoblast differentiation by suppressing NF-κB activation in an inflammatory environment. Cell Death Dis (2016) 0.75
Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance. Oncol Lett (2016) 0.75
New horizon in autophagy research. Acta Pharmacol Sin (2013) 0.75
Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway. Oncotarget (2017) 0.75
Why just eat in, when you can also eat out? Autophagy (2012) 0.75
Modulation of Autophagy as a Therapeutic Target for Alzheimer's Disease. Postdoc J (2013) 0.75
The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription. EMBO J (2017) 0.75
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol (2005) 18.23
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol (2008) 17.81
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol (2011) 15.71
Autophagy regulates lipid metabolism. Nature (2009) 13.33
Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol (2009) 13.01
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem (2009) 12.73
A protein conjugation system essential for autophagy. Nature (1998) 12.71
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J (2007) 11.72
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science (2010) 11.29
A ubiquitin-like system mediates protein lipidation. Nature (2000) 10.61
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J (2007) 9.65
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell (2006) 9.47
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol (2008) 9.37
Formation process of autophagosome is traced with Apg8/Aut7p in yeast. J Cell Biol (1999) 9.33
A unified nomenclature for yeast autophagy-related genes. Dev Cell (2003) 9.18
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct (1998) 9.18
Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science (2006) 9.17
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol (2006) 9.17
Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol (2008) 8.92
TFEB links autophagy to lysosomal biogenesis. Science (2011) 8.87
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J (2001) 8.84
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci U S A (1982) 8.71
Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell (2004) 8.53
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol (2007) 8.29
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci U S A (2009) 8.25
FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab (2007) 8.05
Bidirectional transport of amino acids regulates mTOR and autophagy. Cell (2009) 7.88
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature (2007) 7.74
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell (2008) 7.61
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol (2000) 7.48
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev (2011) 7.43
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol (2009) 7.35
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe (2007) 7.34
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature (2007) 7.21
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol (2008) 7.16
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell (2008) 7.14
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell (2007) 7.09
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci (2006) 6.98
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell (2009) 6.88
Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature (2009) 6.74
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol (2009) 6.69
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature (2000) 6.34
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J Biol Chem (2005) 6.27
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol (2007) 6.22
Pancreatic cancers require autophagy for tumor growth. Genes Dev (2011) 6.17
The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem (1997) 6.09
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell (2009) 5.97
The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol (2010) 5.95
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem (2005) 5.89
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell (2009) 5.85
Autophagy, immunity, and microbial adaptations. Cell Host Microbe (2009) 5.84
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol (2009) 5.83
Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell (2009) 5.77
Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci U S A (2001) 5.59
Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. Cell (2005) 5.57
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene (1997) 5.53
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat Cell Biol (2008) 5.50
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A (2008) 5.48
Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol (1995) 5.41
Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol (2005) 5.21
Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci (2004) 5.19
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ (2006) 5.18
NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci U S A (2007) 5.14
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell (2010) 5.09
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol (2009) 5.06
Induction of autophagy by spermidine promotes longevity. Nat Cell Biol (2009) 5.00
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem (2009) 4.90
A receptor for the selective uptake and degradation of proteins by lysosomes. Science (1996) 4.89
Methods for monitoring autophagy from yeast to human. Autophagy (2007) 4.89
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell (2004) 4.72
Endogenous HMGB1 regulates autophagy. J Cell Biol (2010) 4.71
Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (2008) 4.71
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell (1999) 4.68
A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science (1989) 4.58
Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway. Dev Cell (2002) 4.49
Discovery of drug mode of action and drug repositioning from transcriptional responses. Proc Natl Acad Sci U S A (2010) 4.35
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. J Biol Chem (2007) 4.33
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol (2000) 4.30
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ (2006) 4.29
Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. J Cell Biol (2001) 4.25
Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J Cell Biol (1990) 4.20
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Regulation of autophagy by the inositol trisphosphate receptor. Cell Death Differ (2007) 4.12
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell (2005) 4.02
Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol (1995) 4.01
A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Mol Cell (2006) 3.98
Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J (1999) 3.97
The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways. J Biol Chem (2000) 3.97
Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae. J Biol Chem (1998) 3.93
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J (2010) 3.90
Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene (1997) 3.88
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem (2008) 3.86
Autophagic control of listeria through intracellular innate immune recognition in drosophila. Nat Immunol (2008) 3.78
Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell (2005) 3.71
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell (2005) 21.01
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Methods in mammalian autophagy research. Cell (2010) 20.08
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol (2005) 18.60
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 16.67
Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol (2007) 15.47
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell (2007) 14.63
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet (2004) 14.31
The hallmarks of aging. Cell (2013) 14.29
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90
The pathophysiology of mitochondrial cell death. Science (2004) 13.87
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell (2004) 12.71
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature (2004) 11.82
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J (2007) 11.72
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol (2005) 11.63
Autophagy and the integrated stress response. Mol Cell (2010) 11.21
Autophagy in immunity and inflammation. Nature (2011) 11.16
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science (2004) 10.77
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med (2006) 10.54
Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol (2005) 10.27
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J (2007) 9.65
Autophagy defends cells against invading group A Streptococcus. Science (2004) 9.53
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20
A unified nomenclature for yeast autophagy-related genes. Dev Cell (2003) 9.18
Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science (2006) 9.17
Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science (2003) 9.17
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell (2009) 9.14
Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol (2010) 9.06
TFEB links autophagy to lysosomal biogenesis. Science (2011) 8.87
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol (2004) 8.85
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med (2007) 8.82
Autophagy in human health and disease. N Engl J Med (2013) 8.71
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res (2007) 8.44
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature (2007) 7.74
Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (2007) 7.65
Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol (2007) 7.43
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe (2007) 7.34
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell (2008) 7.32
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol (2008) 7.16
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell (2008) 7.14
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell (2007) 7.09
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci (2006) 6.98
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell (2009) 6.88
Alpha-Synuclein is degraded by both autophagy and the proteasome. J Biol Chem (2003) 6.84
Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol (2008) 6.78
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 6.73
Escape of intracellular Shigella from autophagy. Science (2004) 6.64
Immunological aspects of cancer chemotherapy. Nat Rev Immunol (2008) 6.61
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron (2007) 6.60
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet (2002) 6.56
Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat Cell Biol (2010) 6.41
Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell (2007) 6.39
Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev (2010) 6.35
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26