Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6.

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Published in Hum Mol Genet on November 26, 2008

Authors

Hayley J Little1, Nicholas K Rorick, Ling-I Su, Clair Baldock, Saimon Malhotra, Tom Jowitt, Lokesh Gakhar, Ramaswamy Subramanian, Brian C Schutte, Michael J Dixon, Paul Shore

Author Affiliations

1: Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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