Paul M Hassoun

Author PubWeight™ 123.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 2009 3.96
2 Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med 2006 3.59
3 Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. Am J Respir Crit Care Med 2004 3.59
4 Endothelial dysfunction in pulmonary hypertension. Circulation 2004 2.82
5 Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am J Respir Crit Care Med 2004 2.73
6 Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation 2013 2.64
7 Tricuspid annular plane systolic excursion is a robust outcome measure in systemic sclerosis-associated pulmonary arterial hypertension. J Rheumatol 2011 2.48
8 Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype. Chest 2010 2.35
9 Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation 2009 2.17
10 Clinical differences between idiopathic and scleroderma-related pulmonary hypertension. Arthritis Rheum 2006 2.04
11 Perspectives on oral pulmonary hypertension therapies recently approved by the U.S. Food and Drug Administration. Ann Am Thorac Soc 2015 2.02
12 Pulmonary capillary wedge pressure augments right ventricular pulsatile loading. Circulation 2011 1.92
13 Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT. Circulation 2011 1.91
14 Use of consomic rats for genomic insights into ventilator-associated lung injury. Am J Physiol Lung Cell Mol Physiol 2007 1.86
15 Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension. J Am Coll Cardiol 2009 1.78
16 PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support. Circ Heart Fail 2008 1.75
17 Epidermal growth factor receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice. Transl Res 2008 1.57
18 Treatment of sarcoidosis-associated pulmonary hypertension. A two-center experience. Chest 2008 1.57
19 Modulation of inducible nitric oxide synthase by hypoxia in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 2002 1.55
20 Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice. J Immunol 2009 1.53
21 Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension. Am J Respir Crit Care Med 2010 1.44
22 Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways. Am J Physiol Lung Cell Mol Physiol 2006 1.42
23 Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. Am J Respir Crit Care Med 2007 1.41
24 Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease. Arthritis Rheum 2009 1.40
25 Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2. J Biol Chem 2002 1.40
26 Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 2008 1.38
27 Inducible nitric oxide synthase contributes to ventilator-induced lung injury. Am J Respir Crit Care Med 2005 1.35
28 Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Heart Circ Physiol 2003 1.34
29 Regulation of endothelial barrier function by reactive oxygen and nitrogen species. Microvasc Res 2008 1.34
30 Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Am J Pathol 2010 1.33
31 Regression of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Lung Cell Mol Physiol 2007 1.30
32 Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Transl Res 2008 1.27
33 Activation of the STAT pathway in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2004 1.25
34 Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury. PLoS One 2009 1.24
35 Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail 2013 1.21
36 Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways. Am J Physiol Cell Physiol 2005 1.18
37 Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 2008 1.18
38 Myocardial delayed enhancement in pulmonary hypertension: pulmonary hemodynamics, right ventricular function, and remodeling. AJR Am J Roentgenol 2011 1.15
39 Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. Am J Respir Cell Mol Biol 2009 1.12
40 Redox imbalance and ventilator-induced lung injury. Antioxid Redox Signal 2007 1.10
41 Long-term outcome of bosentan treatment in idiopathic pulmonary arterial hypertension and pulmonary arterial hypertension associated with the scleroderma spectrum of diseases. J Heart Lung Transplant 2005 1.09
42 Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice. J Immunol 2009 1.09
43 Activated protein C protects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol 2009 1.09
44 Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med 2010 1.09
45 Vascular receptor autoantibodies in pulmonary arterial hypertension. Am J Respir Crit Care Med 2015 1.08
46 Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury. J Appl Physiol (1985) 2008 1.08
47 Trials and Tribulations of Therapies for the Acute Respiratory Distress Syndrome. Crit Care Med 2016 1.07
48 Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung. Acta Pharmacol Sin 2010 1.06
49 The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice. Am J Respir Crit Care Med 2009 1.05
50 One hundred years of research in the pathogenesis of pulmonary hypertension. Am J Respir Cell Mol Biol 2005 1.05
51 Immune and inflammatory mechanisms in pulmonary arterial hypertension. Prog Cardiovasc Dis 2012 1.03
52 Systemic sclerosis-associated pulmonary arterial hypertension. Am J Respir Crit Care Med 2010 1.03
53 EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation. Am J Respir Cell Mol Biol 2006 1.02
54 Xanthine oxidoreductase in respiratory and cardiovascular disorders. Am J Physiol Lung Cell Mol Physiol 2008 1.02
55 An official American Thoracic Society Statement: pulmonary hypertension phenotypes. Am J Respir Crit Care Med 2014 1.02
56 Portopulmonary hypertension: a tale of two circulations. Chest 2003 1.00
57 p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor. Am J Respir Cell Mol Biol 2010 1.00
58 Systemic sclerosis-associated pulmonary arterial hypertension. Chest 2013 1.00
59 Right and left ventricular myocardial perfusion reserves correlate with right ventricular function and pulmonary hemodynamics in patients with pulmonary arterial hypertension. Radiology 2010 0.99
60 Pulmonary artery measurements in pulmonary hypertension: the role of computed tomography. J Thorac Imaging 2013 0.98
61 Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase. J Immunol 2012 0.97
62 Outcomes of noncardiac, nonobstetric surgery in patients with PAH: an international prospective survey. Eur Respir J 2012 0.96
63 A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension. Circulation 2011 0.96
64 Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry. Chest 2014 0.96
65 Pulmonary arterial hypertension associated with systemic sclerosis. Expert Rev Respir Med 2011 0.95
66 Pulmonary arterial hypertension: MR imaging-derived first-pass bolus kinetic parameters are biomarkers for pulmonary hemodynamics, cardiac function, and ventricular remodeling. Radiology 2012 0.95
67 Scleroderma lung disease. Clin Rev Allergy Immunol 2011 0.93
68 Cardiac complications of systemic sclerosis: recent progress in diagnosis. Curr Opin Rheumatol 2010 0.92
69 Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma. J Clin Microbiol 2002 0.92
70 Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 2015 0.91
71 Systemic sclerosis-related pulmonary hypertension associated with interstitial lung disease: impact of pulmonary arterial hypertension therapies. Arthritis Rheum 2011 0.91
72 Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study. Radiology 2012 0.91
73 Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004 0.90
74 Increased right ventricular Septomarginal trabeculation mass is a novel marker for pulmonary hypertension: comparison with ventricular mass index and right ventricular mass. Invest Radiol 2011 0.90
75 Upregulation of xanthine oxidase by tobacco smoke condensate in pulmonary endothelial cells. Toxicol Appl Pharmacol 2003 0.89
76 Differential gene expression in chronic hypoxic pulmonary hypertension: effect of simvastatin treatment. Chest 2005 0.87
77 Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3. Am J Respir Cell Mol Biol 2014 0.87
78 Pulmonary endothelial cell NOX. Am J Respir Cell Mol Biol 2012 0.87
79 Pulmonary arterial hypertension in connective tissue diseases. Heart Fail Clin 2012 0.86
80 Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis. Free Radic Biol Med 2013 0.85
81 Macrophage migration inhibitory factor is a novel determinant of cigarette smoke-induced lung damage. Am J Respir Cell Mol Biol 2014 0.85
82 Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients. PLoS One 2012 0.85
83 Estrogen modulates xanthine dehydrogenase/xanthine oxidase activity by a receptor-independent mechanism. Antioxid Redox Signal 2003 0.82
84 Right ventricular dysfunction in chronic lung disease. Cardiol Clin 2012 0.82
85 Therapy for pulmonary arterial hypertension associated with systemic sclerosis. Curr Opin Rheumatol 2009 0.80
86 Right ventricle dysfunction in pulmonary hypertension: mechanisms and modes of detection. Curr Opin Pulm Med 2015 0.79
87 Real-time single-heartbeat fast strain-encoded imaging of right ventricular regional function: normal versus chronic pulmonary hypertension. Magn Reson Med 2010 0.79
88 Interleukin-6 and tumor necrosis factor-α are associated with quality of life-related symptoms in pulmonary arterial hypertension. Ann Am Thorac Soc 2015 0.79
89 N-terminal brain natriuretic peptide in scleroderma-associated pulmonary arterial hypertension. Eur Heart J 2006 0.78
90 Severity of systemic sclerosis-associated pulmonary arterial hypertension in African Americans. Medicine (Baltimore) 2014 0.78
91 Severe respiratory muscle weakness related to long-term colchicine therapy. Respir Care 2004 0.77
92 Pulmonary hypertension due to lung disease and/or hypoxia. Clin Chest Med 2013 0.77
93 Is pulmonary arterial hypertension really a late complication of systemic sclerosis? Chest 2010 0.77
94 Drumming up prognostic significance in a heartbeat in pulmonary arterial hypertension. Am J Respir Crit Care Med 2012 0.77
95 Linking new and old concepts: inflammation meets the Warburg phenomenon in pulmonary arterial hypertension. J Mol Med (Berl) 2011 0.76
96 Prediction of pulmonary artery pressure. Chest 2005 0.75
97 Drs. Mathai and Hassoun reply. J Rheumatol 2013 0.75
98 Inflammatory mechanisms in the pathogenesis of pulmonary arterial hypertension. Compr Physiol 2011 0.75
99 Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome: Clinical Determinants and Association With Outcome From the Fluid and Catheter Treatment Trial Cohort. Crit Care Med 2016 0.75
100 Survival in systemic sclerosis-related pulmonary arterial hypertension in the modern treatment era. Am J Respir Crit Care Med 2009 0.75
101 Moving beyond the "Allegory of the Cave" in the assessment of pulmonary arterial hypertension. J Appl Physiol (1985) 2011 0.75
102 Can we still miss tetrachloroethylene-induced lung disease? The emperor returns in new clothes. Respiration 2005 0.75
103 [Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology]. Turk Kardiyol Dern Ars 2014 0.75
104 Correction: Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice. J Immunol 2017 0.75