From ion channels to complex networks: magic bullet versus magic shotgun approaches to anticonvulsant pharmacotherapy.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 19046822)

Published in Med Hypotheses on November 28, 2008

Authors

Matt T Bianchi1, Jay Pathmanathan, Sydney S Cash

Author Affiliations

1: Beth Israel Deaconess Medical Center, Sleep Medicine, 300 Brookline Ave, KS-4, Boston, MA 02115, United States. thebianchi@gmail.com

Articles by these authors

Reach and grasp by people with tetraplegia using a neurally controlled robotic arm. Nature (2012) 7.87

Single-neuron dynamics in human focal epilepsy. Nat Neurosci (2011) 4.26

Sequential processing of lexical, grammatical, and phonological information within Broca's area. Science (2009) 2.70

Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. Proc Natl Acad Sci U S A (2012) 2.10

Laminar analysis of slow wave activity in humans. Brain (2010) 1.80

Epilepsy as a disorder of cortical network organization. Neuroscientist (2012) 1.70

Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain (2010) 1.62

Individualized localization and cortical surface-based registration of intracranial electrodes. Neuroimage (2011) 1.50

Human seizures self-terminate across spatial scales via a critical transition. Proc Natl Acad Sci U S A (2012) 1.42

Coalescence and fragmentation of cortical networks during focal seizures. J Neurosci (2010) 1.38

Advantages of closed-loop calibration in intracortical brain-computer interfaces for people with tetraplegia. J Neural Eng (2013) 1.38

Obstructive sleep apnea alters sleep stage transition dynamics. PLoS One (2010) 1.26

Network inference with confidence from multivariate time series. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 1.23

Emergence of stable functional networks in long-term human electroencephalography. J Neurosci (2012) 1.20

Avalanche Analysis from Multielectrode Ensemble Recordings in Cat, Monkey, and Human Cerebral Cortex during Wakefulness and Sleep. Front Physiol (2012) 1.18

First-pass selectivity for semantic categories in human anteroventral temporal lobe. J Neurosci (2011) 1.16

Local cortical dynamics of burst suppression in the anaesthetized brain. Brain (2013) 1.12

Spatiotemporal dynamics of neocortical excitation and inhibition during human sleep. Proc Natl Acad Sci U S A (2012) 1.10

Multimodal imaging of repetition priming: Using fMRI, MEG, and intracranial EEG to reveal spatiotemporal profiles of word processing. Neuroimage (2010) 1.09

Emergence of persistent networks in long-term intracranial EEG recordings. J Neurosci (2011) 1.07

Decoding word and category-specific spatiotemporal representations from MEG and EEG. Neuroimage (2010) 1.02

Magnetoencephalography demonstrates multiple asynchronous generators during human sleep spindles. J Neurophysiol (2010) 1.00

Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model. PLoS One (2013) 0.99

An algorithm for seizure onset detection using intracranial EEG. Epilepsy Behav (2011) 0.99

Case records of the Massachusetts General Hospital. Case 19-2005. A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami. N Engl J Med (2005) 0.97

Topographical frequency dynamics within EEG and MEG sleep spindles. Clin Neurophysiol (2010) 0.97

Divergent cortical generators of MEG and EEG during human sleep spindles suggested by distributed source modeling. PLoS One (2010) 0.96

A transition in brain state during propofol-induced unconsciousness. J Neurosci (2014) 0.95

A candidate mechanism underlying the variance of interictal spike propagation. J Neurosci (2012) 0.93

Reducing motion artifacts for long-term clinical NIRS monitoring using collodion-fixed prism-based optical fibers. Neuroimage (2013) 0.91

Comparative power spectral analysis of simultaneous elecroencephalographic and magnetoencephalographic recordings in humans suggests non-resistive extracellular media. J Comput Neurosci (2010) 0.91

Parallel versus serial processing dependencies in the perisylvian speech network: a Granger analysis of intracranial EEG data. Brain Lang (2009) 0.90

Independence of early speech processing from word meaning. Cereb Cortex (2012) 0.87

Calculating the risk benefit equation for aggressive treatment of non-convulsive status epilepticus. Neurocrit Care (2013) 0.86

Real-time segmentation of burst suppression patterns in critical care EEG monitoring. J Neurosci Methods (2013) 0.86

Intracranial microprobe for evaluating neuro-hemodynamic coupling in unanesthetized human neocortex. J Neurosci Methods (2009) 0.86

Emergence of synchronous EEG spindles from asynchronous MEG spindles. Hum Brain Mapp (2011) 0.86

Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies. Neuropharmacology (2009) 0.85

Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG. Front Hum Neurosci (2011) 0.85

Real-time segmentation and tracking of brain metabolic state in ICU EEG recordings of burst suppression. Conf Proc IEEE Eng Med Biol Soc (2013) 0.85

Revising the "Rule of Three" for inferring seizure freedom. Epilepsia (2011) 0.82

Intracranial cortical responses during visual-tactile integration in humans. J Neurosci (2014) 0.81

Modulation of EEG functional connectivity networks in subjects undergoing repetitive transcranial magnetic stimulation. Brain Topogr (2013) 0.81

Probabilistic sleep architecture models in patients with and without sleep apnea. J Sleep Res (2011) 0.81

Network analysis: applications for the developing brain. J Child Neurol (2011) 0.81

Incorporating uncertainty into medical decision making: an approach to unexpected test results. Med Decis Making (2008) 0.81

Absence of early epileptiform abnormalities predicts lack of seizures on continuous EEG. Neurology (2012) 0.80

Contribution of the superior colliculus and the mesencephalic reticular formation to gaze control. Ann N Y Acad Sci (2002) 0.78

Adaptive offset correction for intracortical brain-computer interfaces. IEEE Trans Neural Syst Rehabil Eng (2014) 0.78

Comparative power spectral analysis of simultaneous electroencephalographic and magnetoencephalographic recordings in humans suggests non-resistive extracellular media : EEG and MEG power spectra. J Comput Neurosci (2010) 0.78

Information theoretic quantification of diagnostic uncertainty. Open Med Inform J (2012) 0.78

Wireless behind-the-ear EEG recording device with wireless interface to a mobile device (iPhone/iPod touch). Conf Proc IEEE Eng Med Biol Soc (2014) 0.78

An in silico approach for pre-surgical evaluation of an epileptic cortex. Conf Proc IEEE Eng Med Biol Soc (2014) 0.77

Finding synchrony in the desynchronized EEG: the history and interpretation of gamma rhythms. Front Integr Neurosci (2013) 0.76

Weighing the value of memory loss in the surgical evaluation of left temporal lobe epilepsy: a decision analysis. Epilepsia (2014) 0.76

Early detection of human focal seizures based on cortical multiunit activity. Conf Proc IEEE Eng Med Biol Soc (2014) 0.75

Inferring seizure frequency from brief EEG recordings. J Clin Neurophysiol (2013) 0.75

Review: Human Intracortical recording and neural decoding for brain-computer interfaces. IEEE Trans Neural Syst Rehabil Eng (2017) 0.75

Predicting seizures from local field potentials recorded via intracortical microelectrode arrays. Conf Proc IEEE Eng Med Biol Soc (2016) 0.75

Low-Power, 8-Channel EEG Recorder and Seizure Detector ASIC for a Subdermal Implantable System. IEEE Trans Biomed Circuits Syst (2016) 0.75

A modular, closed-loop platform for intracranial stimulation in people with neurological disorders. Conf Proc IEEE Eng Med Biol Soc (2016) 0.75

Automated epileptiform spike detection via affinity propagation-based template matching. Conf Proc IEEE Eng Med Biol Soc (2017) 0.75