Published in Cardiovasc Res on December 01, 2008
Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev (2010) 2.68
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
CaMKII in the cardiovascular system: sensing redox states. Physiol Rev (2011) 1.67
Role of microRNAs in the reperfused myocardium towards post-infarct remodelling. Cardiovasc Res (2011) 1.47
Mitochondrial aldehyde dehydrogenase and cardiac diseases. Cardiovasc Res (2010) 1.39
Extracellular matrix roles during cardiac repair. Life Sci (2010) 1.32
Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage. Dis Markers (2013) 1.16
NADPH oxidases and cardiac remodelling. Heart Fail Rev (2011) 1.14
Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol (2011) 1.14
Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction. J Mol Cell Cardiol (2009) 1.09
Safety and efficacy of high-dose adeno-associated virus 9 encoding sarcoplasmic reticulum Ca(2+) adenosine triphosphatase delivered by molecular cardiac surgery with recirculating delivery in ovine ischemic cardiomyopathy. J Thorac Cardiovasc Surg (2014) 1.06
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion. Proc Natl Acad Sci U S A (2011) 1.05
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction. Antioxid Redox Signal (2012) 1.04
Exercise training inhibits inflammatory cytokines and more than prevents myocardial dysfunction in rats with sustained beta-adrenergic hyperactivity. J Physiol (2010) 1.02
Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutr Metab (Lond) (2009) 1.01
Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis. Antioxid Redox Signal (2012) 1.00
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system. Sci Transl Med (2014) 0.99
Thymosin beta 4 prevents oxidative stress by targeting antioxidant and anti-apoptotic genes in cardiac fibroblasts. PLoS One (2011) 0.98
Molecular targets for anti-oxidative protection of green tea polyphenols against myocardial ischemic injury. Biomedicine (Taipei) (2014) 0.98
MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart. Am J Physiol Heart Circ Physiol (2011) 0.97
miR-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction. Stem Cell Reports (2014) 0.97
How can we cure a heart "in flame"? A translational view on inflammation in heart failure. Basic Res Cardiol (2013) 0.94
Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus. Inflamm Res (2013) 0.94
Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation. PLoS One (2012) 0.93
Oxidative stress-induced Notch1 signaling promotes cardiogenic gene expression in mesenchymal stem cells. Stem Cell Res Ther (2013) 0.93
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity. PLoS One (2012) 0.92
Azelnidipine protects myocardium in hyperglycemia-induced cardiac damage. Cardiovasc Diabetol (2010) 0.92
Administration of pigment epithelium-derived factor inhibits left ventricular remodeling and improves cardiac function in rats with acute myocardial infarction. Am J Pathol (2011) 0.91
Attenuation of myocardial injury in mice with functional deletion of the circadian rhythm gene mPer2. Am J Physiol Heart Circ Physiol (2010) 0.91
Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism. PLoS One (2013) 0.90
Evaluation of inflammatory response to acute ischemia using near-infrared fluorescent reactive oxygen sensors. Mol Imaging Biol (2013) 0.89
Exercise training prior to myocardial infarction attenuates cardiac deterioration and cardiomyocyte dysfunction in rats. Clinics (Sao Paulo) (2013) 0.88
Alteration of energy substrates and ROS production in diabetic cardiomyopathy. Mediators Inflamm (2013) 0.88
Myocardial matrix metalloproteinase-2: inside out and upside down. J Mol Cell Cardiol (2014) 0.88
Deficiency of ataxia telangiectasia mutated kinase modulates cardiac remodeling following myocardial infarction: involvement in fibrosis and apoptosis. PLoS One (2013) 0.87
Molecular and cellular mechanisms of cigarette smoke-induced myocardial injury: prevention by vitamin C. PLoS One (2012) 0.87
Oxidative stress: Predictive marker for coronary artery disease. Exp Clin Cardiol (2013) 0.86
The role of oxidative stress and lipid peroxidation in ventricular remodeling induced by tobacco smoke exposure after myocardial infarction. Clinics (Sao Paulo) (2009) 0.85
An emerging role for the miR-26 family in cardiovascular disease. Trends Cardiovasc Med (2014) 0.84
Proteomic analysis reveals late exercise effects on cardiac remodeling following myocardial infarction. J Proteomics (2010) 0.84
Specific antioxidant selenoproteins are induced in the heart during hypertrophy. Arch Biochem Biophys (2011) 0.84
Inhibition of apoptosis signal-regulating kinase 1 reduces myocardial ischemia-reperfusion injury in the mouse. J Am Heart Assoc (2012) 0.84
A nonthoracotomy myocardial infarction model in an ovine using autologous platelets. Biomed Res Int (2013) 0.82
Molecular basis of cardioprotective effect of antioxidant vitamins in myocardial infarction. Biomed Res Int (2013) 0.82
Modification of oxidative stress on gene expression profiling in the rat infarcted heart. Mol Cell Biochem (2013) 0.82
Co-treatment with conjugated linoleic acid and nitrite protects against myocardial infarction. Redox Biol (2013) 0.82
N-acetylcysteine administration prevents nonthyroidal illness syndrome in patients with acute myocardial infarction: a randomized clinical trial. J Clin Endocrinol Metab (2014) 0.81
Role of apoptosis signal-regulating kinase-1-c-Jun NH2-terminal kinase-p38 signaling in voltage-gated K+ channel remodeling of the failing heart: regulation by thioredoxin. Antioxid Redox Signal (2010) 0.81
Beneficial and harmful effects of exercise in hypertensive patients: the role of oxidative stress. Hypertens Res (2016) 0.81
Stem cells in the diabetic infarcted heart. Heart Fail Rev (2010) 0.80
Experimental Myocardial Infarction Upregulates Circulating Fibroblast Growth Factor-23. J Bone Miner Res (2015) 0.80
Aerobic interval training attenuates mitochondrial dysfunction in rats post-myocardial infarction: roles of mitochondrial network dynamics. Int J Mol Sci (2014) 0.80
Beneficial effects of muscone on cardiac remodeling in a mouse model of myocardial infarction. Int J Mol Med (2014) 0.79
VEGF-C/VEGFR-3 pathway promotes myocyte hypertrophy and survival in the infarcted myocardium. Am J Transl Res (2015) 0.79
The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity. Invest New Drugs (2010) 0.79
Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats. Inflamm Res (2011) 0.78
Superoxide scavenging and Akt inhibition in myocardium ameliorate pressure overload-induced NF-κB activation and cardiac hypertrophy. Physiol Genomics (2010) 0.78
Effective Components of Panax quinquefolius and Corydalis tuber Protect Myocardium through Attenuating Oxidative Stress and Endoplasmic Reticulum Stress. Evid Based Complement Alternat Med (2013) 0.78
Temporal and spatial changes in collateral formation and function during chronic myocardial ischemia. J Am Coll Surg (2010) 0.78
Atrophic cardiac remodeling induced by taurine deficiency in Wistar rats. PLoS One (2012) 0.78
Impaired High-Density Lipoprotein Anti-Oxidant Function Predicts Poor Outcome in Critically Ill Patients. PLoS One (2016) 0.78
Iron-induced myocardial injury: an alarming side effect of superparamagnetic iron oxide nanoparticles. J Cell Mol Med (2015) 0.78
Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy. Heart Int (2011) 0.78
Nanomedicines for Endothelial Disorders. Nano Today (2015) 0.77
Redox regulation of ion channels in the pulmonary circulation. Antioxid Redox Signal (2014) 0.77
Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway. Int J Mol Med (2016) 0.77
TM-1-1DP exerts protective effect against myocardial ischemia reperfusion injury via AKT-eNOS pathway. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.77
Pretreatment of therapeutic cells with poly(ADP-ribose) polymerase inhibitor enhances their efficacy in an in vitro model of cell-based therapy in myocardial infarct. Int J Mol Med (2012) 0.77
Oxidative stress decreases microtubule growth and stability in ventricular myocytes. J Mol Cell Cardiol (2016) 0.77
NADPH Oxidase/ROS-Dependent VCAM-1 Induction on TNF-α-Challenged Human Cardiac Fibroblasts Enhances Monocyte Adhesion. Front Pharmacol (2016) 0.76
Allicin improves cardiac function by protecting against apoptosis in rat model of myocardial infarction. Chin J Integr Med (2016) 0.76
Decrease in plasma cyclophilin A concentration at 1 month after myocardial infarction predicts better left ventricular performance and synchronicity at 6 months: a pilot study in patients with ST elevation myocardial infarction. Int J Biol Sci (2015) 0.75
Action mechanism and cardiovascular effect of anthocyanins: a systematic review of animal and human studies. J Transl Med (2016) 0.75
Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats. BMC Pharmacol Toxicol (2017) 0.75
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nat Commun (2017) 0.75
Compatibility of Astragalus and Salvia extract inhibits myocardial fibrosis and ventricular remodeling by regulation of protein kinase D1 protein. Int J Clin Exp Med (2015) 0.75
Autophagy decreases alveolar macrophage apoptosis by attenuating endoplasmic reticulum stress and oxidative stress. Oncotarget (2016) 0.75
Modification of Caffeic Acid with Pyrrolidine Enhances Antioxidant Ability by Activating AKT/HO-1 Pathway in Heart. PLoS One (2016) 0.75
Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion. EJNMMI Res (2015) 0.75
Plasma von Willebrand factor level is transiently elevated in a rat model of acute myocardial infarction. Exp Ther Med (2015) 0.75
A novel high throughput approach to screen for cardiac arrhythmic events following stem cell treatment. Med Hypotheses (2015) 0.75
The emerging role of interleukin-37 in cardiovascular diseases. Immun Inflamm Dis (2017) 0.75
Peri-infarct zone characterized by cardiac magnetic resonance imaging is directly associated with the inflammatory activity during acute phase myocardial infarction. Inflammation (2014) 0.75
Proteomic footprint of myocardial ischemia/reperfusion injury: Longitudinal study of the at-risk and remote regions in the pig model. Sci Rep (2017) 0.75
Protective effects of Xinji'erkang on myocardial infarction induced cardiac injury in mice. BMC Complement Altern Med (2017) 0.75
Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells Attenuate Cigarette Smoke-Induced Cardiac Remodeling and Dysfunction. Front Pharmacol (2017) 0.75
Vitamin C Deficiency Reduces Muscarinic Receptor Coronary Artery Vasoconstriction and Plasma Tetrahydrobiopterin Concentration in Guinea Pigs. Nutrients (2017) 0.75
Fasudil ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats: a possible role of Rho kinase. Naunyn Schmiedebergs Arch Pharmacol (2017) 0.75
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med (2007) 8.82
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature (2012) 4.46
Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation (2002) 2.50
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis. J Clin Invest (2004) 1.79
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc Natl Acad Sci U S A (2003) 1.73
Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy (2010) 1.70
Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy. J Mol Cell Cardiol (2004) 1.68
Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure. J Mol Cell Cardiol (2009) 1.42
Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy. J Mol Cell Cardiol (2002) 1.29
The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. J Am Coll Cardiol (2002) 1.28
The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression. Circ Res (2009) 1.20
Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophy. Circulation (2008) 1.12
Cardiac-specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy. FASEB J (2002) 1.11
Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion. Biochem Biophys Res Commun (2003) 1.05
Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling. FASEB J (2005) 1.04
Classic cadherins regulate tangential migration of precerebellar neurons in the caudal hindbrain. Development (2006) 1.01
Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death. Biochem Biophys Res Commun (2005) 1.01
The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B. J Biol Chem (2003) 0.99
Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing. Neural Dev (2008) 0.95
Progression of heart failure was suppressed by inhibition of apoptosis signal-regulating kinase 1 via transcoronary gene transfer. J Am Coll Cardiol (2007) 0.93
Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period. J Biol Chem (2013) 0.89
Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure. J Am Coll Cardiol (2008) 0.88
The antioxidant edaravone attenuates pressure overload-induced left ventricular hypertrophy. Hypertension (2005) 0.87
Pressure overload induces cardiac dysfunction and dilation in signal transducer and activator of transcription 6-deficient mice. Circulation (2004) 0.86
CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy. Biochem Biophys Res Commun (2005) 0.84
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading. Biochem Biophys Res Commun (2013) 0.83
Calpain protects the heart from hemodynamic stress. J Biol Chem (2011) 0.82
Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes. J Mol Cell Cardiol (2008) 0.81
Toll-like receptor signaling: defensive or offensive for the heart? Circ Res (2008) 0.79
In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model. Eur J Neurosci (2015) 0.75
Inflammation and metabolic cardiomyopathy. Cardiovasc Res (2017) 0.75
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