Published in Mol Cell Biol on December 01, 2008
Ligand-directed signalling at beta-adrenoceptors. Br J Pharmacol (2010) 1.40
New Insights into the p38γ and p38δ MAPK Pathways. J Signal Transduct (2011) 1.01
The beta2-adrenergic receptor on T and B lymphocytes: do we understand it yet? Brain Behav Immun (2011) 1.00
Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure. Br J Pharmacol (2011) 1.00
Neuroendocrine regulation of inflammation. Semin Immunol (2014) 0.95
Adrenergic signaling and oxidative stress: a role for sirtuins? Front Physiol (2013) 0.93
Role of peripheral nerve fibres in acute and chronic inflammation in arthritis. Nat Rev Rheumatol (2012) 0.91
Activation of p38 mitogen-activated protein kinase by norepinephrine in T-lineage cells. Immunology (2010) 0.83
Adrenergic regulation of IgE involves modulation of CD23 and ADAM10 expression on exosomes. J Immunol (2013) 0.79
Regulation of the IgE response. F1000 Biol Rep (2010) 0.77
Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine. BMC Pharmacol Toxicol (2013) 0.77
Probable role of Beta 2-adrenergic receptor gene haplotype in toluene diisocyanate-induced asthma. Allergy Asthma Immunol Res (2010) 0.76
β2-adrenoceptor agonists can both stimulate and inhibit glucose uptake in mouse soleus muscle through ligand-directed signalling. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.75
Seven-transmembrane receptors. Nat Rev Mol Cell Biol (2002) 11.50
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science (1994) 10.99
Transduction of receptor signals by beta-arrestins. Science (2005) 9.87
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem (1995) 9.56
Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med (1989) 6.22
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem (2005) 4.91
cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell (1997) 3.93
Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proc Natl Acad Sci U S A (2003) 3.75
Epac: a new cAMP target and new avenues in cAMP research. Nat Rev Mol Cell Biol (2003) 3.42
T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation. Science (1990) 3.23
PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. Physiol Rev (2005) 3.12
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol Cell Biol (2000) 2.96
Protein tyrosine phosphatases and the immune response. Nat Rev Immunol (2005) 2.88
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science (1997) 2.86
The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol (2006) 2.68
Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav Immun (2007) 2.66
Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem J (2003) 2.42
Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J Biol Chem (1993) 2.02
Protein tyrosine phosphatases in autoimmunity. Annu Rev Immunol (2008) 1.90
The CH series of murine B cell lymphomas: neoplastic analogues of Ly-1+ normal B cells. Immunol Rev (1986) 1.81
Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies. Mol Pharmacol (2004) 1.79
MAP kinase pathways activated by stress: the p38 MAPK pathway. Crit Care Med (2000) 1.78
Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase. Nat Cell Biol (1999) 1.62
Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody. J Exp Med (1996) 1.61
Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation. Proc Natl Acad Sci U S A (1992) 1.55
Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system. J Biol Chem (2002) 1.50
Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation. J Biol Chem (2005) 1.50
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J Immunol (1996) 1.45
Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice. Blood (2007) 1.45
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.40
The activation of p38 MAPK by the beta-adrenergic agonist isoproterenol in rat epididymal fat cells. FEBS Lett (1998) 1.32
beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes. J Biol Chem (2000) 1.32
p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes. J Immunol (1998) 1.26
IgE in asthma and atopy: cellular and molecular connections. J Clin Invest (1999) 1.25
Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades. Biochem Pharmacol (1998) 1.23
p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta -adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation. J Biol Chem (2000) 1.22
Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location. Biochem J (2004) 1.20
Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest (2007) 1.17
Adverse effects of beta-agonists: are they clinically relevant? Am J Respir Med (2003) 1.14
Stimulation of the B cell receptor, CD86 (B7-2), and the beta 2-adrenergic receptor intrinsically modulates the level of IgG1 and IgE produced per B cell. J Immunol (2000) 1.14
Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase). Eur J Immunol (1992) 1.13
Protein tyrosine phosphatases in T cell physiology. Mol Immunol (2004) 1.12
Strategies for developing protein tyrosine phosphatase inhibitors. Methods (2007) 1.10
Selective regulation of mature IgG1 transcription by CD86 and beta 2-adrenergic receptor stimulation. J Immunol (2003) 1.10
Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation. Mol Cell Biol (2001) 1.08
CD86 and beta2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B Expression and binding to the 3'-IgH enhancer in B cells. J Biol Chem (2004) 1.04
Suppression of antigen-specific Th2 cell-dependent IgM and IgG1 production following norepinephrine depletion in vivo. J Immunol (1999) 1.03
The level of IgE produced by a B cell is regulated by norepinephrine in a p38 MAPK- and CD23-dependent manner. J Immunol (2006) 1.02
Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site. J Mol Biol (2005) 1.00
Cutting edge: IL-4 induces suppressor of cytokine signaling-3 expression in B cells by a mechanism dependent on activation of p38 MAPK. J Immunol (2005) 0.95
B cell receptor- and beta 2-adrenergic receptor-induced regulation of B7-2 (CD86) expression in B cells. J Immunol (2002) 0.92
Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors. J Immunol (2001) 0.92
Phenylarsine oxide augments tyrosine phosphorylation in hematopoietic cells. Eur J Haematol (1992) 0.86
Activation of antigen-specific CD4+ Th2 cells and B cells in vivo increases norepinephrine release in the spleen and bone marrow. J Immunol (2000) 0.83
Beta 2-adrenoceptor stimulation increases the number of antigen-specific precursor B lymphocytes that differentiate into IgM-secreting cells without affecting burst size. J Immunol (1992) 0.81
Impaired proliferation and survival of activated B cells in transgenic mice that express a dominant-negative cAMP-response element-binding protein transcription factor in B cells. J Biol Chem (2002) 0.81
Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav Immun (2007) 2.66
CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation. J Neurosci (2004) 1.71
Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation. Exp Neurol (2007) 1.52
It takes nerve to tell T and B cells what to do. J Leukoc Biol (2006) 1.51
Natural killer cells do not mediate facial motoneuron survival after facial nerve transection. Brain Behav Immun (2003) 1.50
CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection. Brain Behav Immun (2003) 1.46
Spinal cord injury triggers systemic autoimmunity: evidence for chronic B lymphocyte activation and lupus-like autoantibody synthesis. J Neurochem (2006) 1.25
Immune-mediated neuroprotection of axotomized mouse facial motoneurons is dependent on the IL-4/STAT6 signaling pathway in CD4(+) T cells. Exp Neurol (2006) 1.21
CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. Eur J Immunol (2005) 1.20
Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice. Brain Behav Immun (2005) 1.20
Role of the immune system in the maintenance of mouse facial motoneuron viability after nerve injury. Brain Behav Immun (2005) 1.14
Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury. J Neurochem (2009) 1.11
Selective regulation of mature IgG1 transcription by CD86 and beta 2-adrenergic receptor stimulation. J Immunol (2003) 1.10
CD86 and beta2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B Expression and binding to the 3'-IgH enhancer in B cells. J Biol Chem (2004) 1.04
CD86 regulates IgG1 production via a CD19-dependent mechanism. J Immunol (2007) 1.03
The level of IgE produced by a B cell is regulated by norepinephrine in a p38 MAPK- and CD23-dependent manner. J Immunol (2006) 1.02
Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy. Brain Behav Immun (2007) 1.01
CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase C gamma 2/protein kinase C alpha beta signaling pathways. J Immunol (2006) 1.00
IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection. Brain Behav Immun (2010) 0.97
Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice. ASN Neuro (2009) 0.96
B cell receptor- and beta 2-adrenergic receptor-induced regulation of B7-2 (CD86) expression in B cells. J Immunol (2002) 0.92
Multifunctional microbubbles for image-guided antivascular endothelial growth factor therapy. J Biomed Opt (2010) 0.92
Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice. J Comp Neurol (2011) 0.90
Functional recovery after facial nerve crush is delayed in severe combined immunodeficient mice. Brain Behav Immun (2002) 0.88
Functional recovery and facial motoneuron survival are influenced by immunodeficiency in crush-axotomized mice. Exp Neurol (2009) 0.86
Use of laser microdissection in the investigation of facial motoneuron and neuropil molecular phenotypes after peripheral axotomy. Exp Neurol (2010) 0.86
CD4+ T cell-mediated neuroprotection is independent of T cell-derived BDNF in a mouse facial nerve axotomy model. Brain Behav Immun (2012) 0.85
CD86 and beta2-adrenergic receptor stimulation regulate B-cell activity cooperatively. Trends Immunol (2005) 0.85
Differential actions of pituitary adenylyl cyclase-activating polypeptide and interferon gamma on Th2- and Th1-associated chemokine expression in cultured murine microglia. J Neurodegener Regen (2008) 0.85
CD8+ T cells negatively regulate IL-4-dependent, IgG1-dominant posttransplant alloantibody production. J Immunol (2010) 0.84
Epigenetic regulation of beta2-adrenergic receptor expression in T(H)1 and T(H)2 cells. Brain Behav Immun (2010) 0.84
CD4+CD25+ regulatory T cells and CD1-restricted NKT cells do not mediate facial motoneuron survival after axotomy. J Neuroimmunol (2006) 0.82
Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice. J Neuroimmunol (2009) 0.81
Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy. Neurosci Lett (2010) 0.81
Axotomy-induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice. J Comp Neurol (2014) 0.80
Adrenergic regulation of IgE involves modulation of CD23 and ADAM10 expression on exosomes. J Immunol (2013) 0.79
Effects of facial nerve axotomy on Th2-associated and Th1-associated chemokine mRNA expression in the facial motor nucleus of wild-type and presymptomatic SOD1 mice. J Neurodegener Regen (2009) 0.78
Tissue specific effects of the beta 2-adrenergic agonist salbutamol on LPS-induced IFN-gamma, IL-10 and TGF-beta responses in vivo. J Neuroimmunol (2004) 0.78
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes. J Immunol (2012) 0.78
Immune cell-mediated neuroprotection is independent of estrogen action through estrogen receptor-alpha. Metab Brain Dis (2012) 0.75